R Senior

Summary

Publications

  1. doi request reprint Comparison of sulfur hexafluoride microbubble (SonoVue)-enhanced myocardial contrast echocardiography with gated single-photon emission computed tomography for detection of significant coronary artery disease: a large European multicenter study
    Roxy Senior
    Department of Cardiology, Royal Brompton Hospital and Northwick Park Hospital, London, Harrow, United Kingdom Electronic address
    J Am Coll Cardiol 62:1353-61. 2013
  2. pmc To revascularize or not to revascularize: a dilemma in heart failure
    Roxy Senior
    Department of Cardiovascular Medicine, Northwick Park Hospital and Institute for Medical Research, Harrow, Middlesex, UK
    CMAJ 175:372. 2006
  3. ncbi request reprint Myocardial contrast echocardiography: an innovative technique to assess myocardial perfusion in hypertensive patients
    Roxy Senior
    Department of Cardiovascular Medicine, Northwick Park Hospital and Institute for Medical Research, Harrow Middlesex, United Kingdom
    Am J Hypertens 20:539-40. 2007
  4. ncbi request reprint Imagify (perflubutane polymer microspheres) injectable suspension for the assessment of coronary artery disease
    Roxy Senior
    Department of Cardiovascular Medicine and Institute of Postgraduate Medical Education and Research, Northwick Park Hospital, Harrow, Middlesex, UK
    Expert Rev Cardiovasc Ther 5:413-21. 2007
  5. doi request reprint Detection of coronary artery disease with perfusion stress echocardiography using a novel ultrasound imaging agent: two Phase 3 international trials in comparison with radionuclide perfusion imaging
    Roxy Senior
    Department of Cardiovascular Medicine, Northwick Park Hospital, Watford Road, Harrow, Middlesex HAI 3UJ, UK
    Eur J Echocardiogr 10:26-35. 2009
  6. doi request reprint Contrast echocardiography: evidence-based recommendations by European Association of Echocardiography
    Roxy Senior
    Department of Cardiology, Northwick Park Hospital, Imperial College, London, Harrow HA1 3UJ, UK
    Eur J Echocardiogr 10:194-212. 2009
  7. pmc Ethnic differences in the prevalence and aetiology of left ventricular systolic dysfunction in the community: the Harrow heart failure watch
    G I W Galasko
    Department of Cardiovascular Medicine, Northwick Park Hospital, Harrow, Middlesex, UK
    Heart 91:595-600. 2005
  8. ncbi request reprint An update on contrast echocardiography
    R Chelliah
    Department of Cardiology, Middlesex University London, Northwick Park Hospital, Harrow, UK
    Minerva Cardioangiol 57:483-93. 2009
  9. ncbi request reprint Power doppler harmonic imaging: a feasibility study of a new technique for the assessment of myocardial perfusion
    R Senior
    Department of Cardiovascular Medicine, Northwick Park Hospital, and Institute for Medical Research, Harrow, UK
    Am Heart J 139:245-51. 2000
  10. ncbi request reprint Effect of revascularization on left ventricular remodeling in patients with heart failure from severe chronic ischemic left ventricular dysfunction
    R Senior
    Department of Cardiovascular Medicine, Northwick Park, Harrow, United Kingdom
    Am J Cardiol 88:624-9. 2001

Collaborators

Detail Information

Publications68

  1. doi request reprint Comparison of sulfur hexafluoride microbubble (SonoVue)-enhanced myocardial contrast echocardiography with gated single-photon emission computed tomography for detection of significant coronary artery disease: a large European multicenter study
    Roxy Senior
    Department of Cardiology, Royal Brompton Hospital and Northwick Park Hospital, London, Harrow, United Kingdom Electronic address
    J Am Coll Cardiol 62:1353-61. 2013
    ....
  2. pmc To revascularize or not to revascularize: a dilemma in heart failure
    Roxy Senior
    Department of Cardiovascular Medicine, Northwick Park Hospital and Institute for Medical Research, Harrow, Middlesex, UK
    CMAJ 175:372. 2006
  3. ncbi request reprint Myocardial contrast echocardiography: an innovative technique to assess myocardial perfusion in hypertensive patients
    Roxy Senior
    Department of Cardiovascular Medicine, Northwick Park Hospital and Institute for Medical Research, Harrow Middlesex, United Kingdom
    Am J Hypertens 20:539-40. 2007
  4. ncbi request reprint Imagify (perflubutane polymer microspheres) injectable suspension for the assessment of coronary artery disease
    Roxy Senior
    Department of Cardiovascular Medicine and Institute of Postgraduate Medical Education and Research, Northwick Park Hospital, Harrow, Middlesex, UK
    Expert Rev Cardiovasc Ther 5:413-21. 2007
    ..This article provides an overview of Imagify, a new ultrasound contrast agent...
  5. doi request reprint Detection of coronary artery disease with perfusion stress echocardiography using a novel ultrasound imaging agent: two Phase 3 international trials in comparison with radionuclide perfusion imaging
    Roxy Senior
    Department of Cardiovascular Medicine, Northwick Park Hospital, Watford Road, Harrow, Middlesex HAI 3UJ, UK
    Eur J Echocardiogr 10:26-35. 2009
    ..PSE is a novel technique for evaluating myocardial perfusion. RAMP (real-time assessment of myocardial perfusion)-1 and -2 were international, Phase 3 trials that evaluated the ability of PSE with Imagify, to detect CAD...
  6. doi request reprint Contrast echocardiography: evidence-based recommendations by European Association of Echocardiography
    Roxy Senior
    Department of Cardiology, Northwick Park Hospital, Imperial College, London, Harrow HA1 3UJ, UK
    Eur J Echocardiogr 10:194-212. 2009
    ..Based on the evidence, recommendations are proposed for the clinical use of contrast echocardiography...
  7. pmc Ethnic differences in the prevalence and aetiology of left ventricular systolic dysfunction in the community: the Harrow heart failure watch
    G I W Galasko
    Department of Cardiovascular Medicine, Northwick Park Hospital, Harrow, Middlesex, UK
    Heart 91:595-600. 2005
    ..To assess ethnic differences in the prevalence and aetiology of left ventricular systolic dysfunction (LVSD) in the community...
  8. ncbi request reprint An update on contrast echocardiography
    R Chelliah
    Department of Cardiology, Middlesex University London, Northwick Park Hospital, Harrow, UK
    Minerva Cardioangiol 57:483-93. 2009
    ..Contrast agents therefore have a significant role in cardiovascular diagnostics and its use can only improve patient care...
  9. ncbi request reprint Power doppler harmonic imaging: a feasibility study of a new technique for the assessment of myocardial perfusion
    R Senior
    Department of Cardiovascular Medicine, Northwick Park Hospital, and Institute for Medical Research, Harrow, UK
    Am Heart J 139:245-51. 2000
    ..The aim of the study was to assess the feasibility of a new technique, power Doppler harmonic imaging (PDHI), for assessing myocardial perfusion through a venous injection of microbubbles, with the use of a new ultrasound contrast agent...
  10. ncbi request reprint Effect of revascularization on left ventricular remodeling in patients with heart failure from severe chronic ischemic left ventricular dysfunction
    R Senior
    Department of Cardiovascular Medicine, Northwick Park, Harrow, United Kingdom
    Am J Cardiol 88:624-9. 2001
    ..Improvement in LV geometry contributes to better LV systolic function, which in turn is the best predictor of survival after revascularization...
  11. doi request reprint Effects of left bundle-branch block on cardiac structure, function, perfusion, and perfusion reserve: implications for myocardial contrast echocardiography versus radionuclide perfusion imaging for the detection of coronary artery disease
    S A Hayat
    Department of Cardiology and Institute of Postgraduate Medical Education and Research, Northwick Park Hospital, Harrow, UK
    Circulation 117:1832-41. 2008
    ....
  12. pmc Is echocardiography a valid tool to screen for left ventricular systolic dysfunction in chronic survivors of acute myocardial infarction? A comparison with radionuclide ventriculography
    G I W Galasko
    Department of Cardiovascular Medicine, Northwick Park Hospital, Harrow, Middlesex HA1 3UJ, UK
    Heart 90:1422-6. 2004
    ....
  13. ncbi request reprint Effect of aging on the prognostic significance of ambulatory systolic, diastolic, and pulse pressure in essential hypertension
    R S Khattar
    Department of Cardiovascular Medicine, Northwick Park and St. Mark's Hospital NHS Trust and Institute for Medical Research, Harrow, Middlesex, United Kingdom
    Circulation 104:783-9. 2001
    ..This may reflect differing underlying hemodynamic mechanisms of hypertension in these age groups...
  14. ncbi request reprint Evaluation of N-terminal pro-B type natriuretic peptide analysis on the Elecsys 1010 and 2010 analysers
    S C Barnes
    Department of Chemical Pathology, St George s Hospital, London, UK
    Ann Clin Biochem 41:459-63. 2004
    ..N-terminal pro-B type natriuretic peptide (NTpBNP) is a potential marker of cardiac failure...
  15. doi request reprint Independent value of left atrial volume index for the prediction of mortality in patients with suspected heart failure referred from the community
    T K Lim
    Department of Cardiovascular Medicine, Institute of Postgraduate Medical, Education and Research, Northwick Park Hospital, Harrow, UK
    Heart 95:1172-8. 2009
    ..However, its value for the prediction of mortality in patients referred for suspected heart failure (HF) is unknown...
  16. ncbi request reprint Wall thickening assessment with tissue harmonic echocardiography results in improved risk stratification for patients with non-ST-segment elevation acute chest pain
    M Hickman
    Department of Cardiovascular Medicine, Northwick Park Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK
    Eur J Echocardiogr 5:142-8. 2004
    ....
  17. pmc Myocardial contrast echocardiography is superior to other known modalities for assessing myocardial reperfusion after acute myocardial infarction
    K Greaves
    Department of Cardiology, St Thomas Hospital, London, UK
    Heart 89:139-44. 2003
    ..Angiographic flow measurements do not define perfusion accurately at a microvascular level, so other techniques which assess flow at a tissue level are to be preferred...
  18. pmc Myocardial viability assessed by dobutamine stress echocardiography predicts reduced mortality early after acute myocardial infarction: determining the risk of events after myocardial infarction (DREAM) study
    J M A Swinburn
    Department of Cardiovascular Medicine, Northwick Park Hospital, Harrow, Middlesex, UK
    Heart 92:44-8. 2006
    ..212 stable consenting patients underwent DSE a mean (SD) of 4.8 (1.5) days after AMI. Patients were then followed up for 803 (297) days...
  19. pmc A prospective comparison of echocardiographic wall motion score index and radionuclide ejection fraction in predicting outcome following acute myocardial infarction
    G I Galasko
    Department of Cardiovascular Medicine, Northwick Park Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK
    Heart 86:271-6. 2001
    ....
  20. ncbi request reprint Intravenous myocardial contrast echocardiography predicts recovery of dysynergic myocardium early after acute myocardial infarction
    J M Swinburn
    Department of Cardiac Research, Northwick Park Hospital, Harrow, United Kingdom
    J Am Coll Cardiol 38:19-25. 2001
    ..CONCLUSIONS: Intravenous delayed triggered MCE can independently detect myocardial viability early after AMI...
  21. ncbi request reprint Enhanced left ventricular endocardial border delineation with an intravenous injection of SonoVue, a new echocardiographic contrast agent: A European multicenter study
    R Senior
    Northwick Park Hospital and Institute of Medical Research, Department of Cardiovascular Medicine, Harrow, Middlesex, United Kingdom
    Echocardiography 17:705-11. 2000
    ..It was concluded that SonoVue is safe and effective in delineating endocardial border, including in patients with suboptimal baseline images...
  22. doi request reprint The increased prevalence of left ventricular hypertrophy and concentric remodeling in U.K. Indian Asians compared with European whites
    N S Chahal
    Department of Cardiovascular Medicine, Northwick Park Hospital, Royal Brompton Hospital, Harrow, London, UK
    J Hum Hypertens 27:288-93. 2013
    ..Investigation of the mechanisms underlying the pathogenesis of LV remodeling and blood pressure etiology may help redress the excess CVD mortality observed in Indian Asians...
  23. ncbi request reprint Contrast echocardiography and acute coronary syndromes
    R Senior
    Northwick Park Hospital and Institute of Medical Research, Harrow, Middlesex, UK
    Ann Cardiol Angeiol (Paris) 51:205-6. 2002
    ..Recent studies have demonstrated the role of MCE to evaluate the value of perfusion and function during rest and dobutamine stress echo in patients early after AMI in terms of risk stratification and management of these patients...
  24. ncbi request reprint Apical hypertrophic cardiomyopathy: bedside diagnosis by intravenous contrast echocardiography
    P Soman
    Department of Cardiovascular Medicine, Northwick Park Hospital, and the Institute of Medical Research, Harrow, United Kingdom
    J Am Soc Echocardiogr 14:311-3. 2001
    ..Intravenous contrast echocardiography, however, revealed typical features of hypertrophic apical cardiomyopathy. Thus contrast echocardiography may be used to establish the diagnosis of this condition...
  25. ncbi request reprint The upper limit of physiological cardiac hypertrophy in elite male and female athletes: the British experience
    G P Whyte
    CRY Centre for Sports Cardiology, Olympic Medical Institute, Northwick Park Hospital, Watford Road, Middlesex HA1 3UJ, Harrow, UK
    Eur J Appl Physiol 92:592-7. 2004
    ..Values in excess of these should be viewed with caution and should prompt further investigation to identify the underlying mechanism...
  26. ncbi request reprint Prognostic value of direct, continuous ambulatory blood pressure monitoring in essential hypertension
    R S Khattar
    Department of Cardiovascular Medicine, Northwick Park and St. Mark's Hospital, NHS Trust and Institute for Medical Research, Harrow, Middlesex, HA1 3UJ
    J Clin Hypertens (Greenwich) 3:90-8. 2001
    ..However, the routine use of ambulatory blood pressure monitoring is not currently recommended, mainly because of a lack of outcome trials based on the treatment of ambulatory blood pressure levels. (c)2001 by Le Jacq Communications, Inc...
  27. ncbi request reprint Portable echocardiography: an innovative tool in screening for cardiac abnormalities in the community
    G I W Galasko
    Department of Cardiovascular Medicine, Northwick Park Hospital, Harrow, Middlesex, UK
    Eur J Echocardiogr 4:119-27. 2003
    ..Echocardiography using new fully portable echocardiography devices would allow community-based cost-effective screening programmes once validated. This study was undertaken to evaluate this further in both high and low-risk subjects...
  28. ncbi request reprint Improved interpretation of dobutamine stress echocardiography following 4 months of systematic training in patients following acute myocardial infarction
    D V Anand
    Northwick Park Hospital, Watford Road, Harrow HA1 3UJ, UK
    Eur J Echocardiogr 5:12-7. 2004
    ....
  29. ncbi request reprint Role of dobutamine echocardiography in detection of myocardial viability for predicting outcome after revascularization in ischemic cardiomyopathy
    R Senior
    Department of Cardiovascular Medicine, Northwick Park Hospital and Institute for Medical Research, Harrow, United Kingdom
    J Am Soc Echocardiogr 14:240-8. 2001
    ..Dobutamine stress echocardiography has emerged as a safe and valuable technique for the assessment of myocardial viability and for the selection of patients for revascularization...
  30. ncbi request reprint Regression of left ventricular remodeling in chronic heart failure: Comparative and combined effects of captopril and carvedilol
    R S Khattar
    Department of Cardiovascular Medicine, Northwick Park and St Mark's Hospital National Health Service Trust, and the Institute for Medical Research, Harrow, United Kingdom
    Am Heart J 142:704-13. 2001
    ..These beneficial effects on remodeling may help to explain the relative prognostic benefits of these therapies...
  31. ncbi request reprint Analytical performance of the N terminal pro B type natriuretic peptide (NT-proBNP) assay on the Elecsys 1010 and 2010 analysers
    P O Collinson
    Department of Chemical Pathology, St George s Hospital, Blackshaw Road, London, SW17 0QT, UK
    Eur J Heart Fail 6:365-8. 2004
    ..89) with NT-proBNP values approximately 5 times greater than BNP (Biosite Triage). In a subset of 320 with normal ejection fraction (>50%) and no risk factors, NT-proBNP values increased with age and were higher in women than men...
  32. ncbi request reprint Myocardial contrast echocardiography for the assessment of left ventricular function
    P Jeetley
    Department of Cardiovascular Medicine, Northwick Park Hospital, Harrow, England, UK
    Minerva Cardioangiol 51:661-6. 2003
    ..As a result contrast enhanced echocardiography may become the gold-standard in the assessment of wall motion and LV function...
  33. pmc Screening for left ventricular dysfunction in the community: role of hand held echocardiography and brain natriuretic peptides
    R Senior
    Department of Cardiovascular Medicine, Northwick Park and St Mark s Hospitals, Harrow, UK
    Heart 89:iii24-8. 2003
  34. pmc Stress echocardiography for the diagnosis and risk stratification of patients with suspected or known coronary artery disease: a critical appraisal. Supported by the British Society of Echocardiography
    R Senior
    Department of Cardiovascular Medicine, Northwick Park Hospital, Harrow HA1 3UJ UK, UK
    Heart 91:427-36. 2005
    ..Tissue Doppler imaging allows quantitation of wall motion. Ready availability and reliability makes stress echocardiography a cost effective technique for the assessment of CAD...
  35. pmc Role of myocardial contrast echocardiography in the clinical evaluation of acute myocardial infarction
    R Senior
    Northwick Park Hospital, Watford Road, Harrow, HA1 3UJ, UK
    Heart 89:1398-400. 2003
  36. doi request reprint Clinical Features of Radiation-induced Carotid Atherosclerosis
    D M Gujral
    Head and Neck Unit, Royal Marsden Hospital, London, UK
    Clin Oncol (R Coll Radiol) 26:94-102. 2014
    ..The use of serum biomarkers in risk-prediction models and the potential value of new imaging techniques as tools for defining earlier surrogate end points will also be discussed. ..
  37. ncbi request reprint Real time contrast echocardiography--a new bedside technique to predict contractile reserve early after acute myocardial infarction
    J M A Swinburn
    Department of Cardiovascular Medicine, Northwick Park Hospital, Harrow, UK
    Eur J Echocardiogr 3:95-9. 2002
    ..We aimed to determine whether microvascular integrity using power pulse inversion can be used to predict contractile reserve early after myocardial infarction...
  38. ncbi request reprint Diagnostic and imaging considerations: role of viability
    Roxy Senior
    Department of Cardiovascular Medicine, Northwick Park Hospital, Watford Road, Harrow Middlesex, HA1 3UJ, United Kingdom
    Heart Fail Rev 11:125-34. 2006
    ..This review focuses on the role of non-invasive testing for myocardial viability in patients with left ventricular systolic dysfunction and heart failure and also outlines the pros and cons of each technique...
  39. ncbi request reprint Vasodilator stress induces infrequent wall thickening abnormalities compared to perfusion defects in mild-to-moderate coronary artery disease: implications for the choice of imaging modality with vasodilator stress
    Prem Soman
    Department of Cardiovascular Medicine, Northwick Park and St Mark s Hospitals and Institute of Medical Research, Harrow, Middlesex, UK
    Echocardiography 21:307-12. 2004
    ..Thus, it is hypothesized that dipyridamole infusion, even at high doses, will result in a disproportionately higher frequency of perfusion defects compared to regional wall thickening abnormalities...
  40. ncbi request reprint Myocardial contrast echocardiography for distinguishing ischemic from nonischemic first-onset acute heart failure: insights into the mechanism of acute heart failure
    Roxy Senior
    Cardiovascular Division, Northwick Park Hospital, Harrow, England, UK
    Circulation 112:1587-93. 2005
    ..The aim of the study was to assess whether myocardial contrast echocardiography (MCE) can identify underlying coronary artery disease (CAD) as the cause of AHF...
  41. ncbi request reprint Accuracy of dipyridamole myocardial contrast echocardiography for the detection of residual stenosis of the infarct-related artery and multivessel disease early after acute myocardial infarction
    Rajesh Janardhanan
    Cardiology Department, Northwick Park Hospital, Harrow, United Kingdom
    J Am Coll Cardiol 43:2247-52. 2004
    ..We aimed to evaluate the ability of vasodilator myocardial contrast echocardiography (MCE) to detect significant infarct-related artery (IRA) stenosis and multivessel disease (MVD) after thrombolysis...
  42. ncbi request reprint Prognostic value of myocardial contrast echocardiography in patients presenting to hospital with acute chest pain and negative troponin
    Paramjit Jeetley
    Department of Cardiovascular Medicine, Northwick Park Hospital and Institute for Medical Education and Research, Harrow, Middlesex, United Kingdom
    Am J Cardiol 99:1369-73. 2007
    ..0003). In conclusion, stress MCE was superior to TIMI risk score and exercise electrocardiography in the assessment of risk in patients with suspected acute coronary syndrome, nondiagnostic electrocardiogram, and negative troponin...
  43. ncbi request reprint Prognostic value of myocardial viability detected by myocardial contrast echocardiography early after acute myocardial infarction
    Girish Dwivedi
    Department of Cardiovascular Medicine, Northwick Park Institute of Medical Research, Northwick Park Hospital, Harrow, Middlesex, United Kingdom
    J Am Coll Cardiol 50:327-34. 2007
    ..This study sought to determine whether residual myocardial viability determined by myocardial contrast echocardiography (MCE) after acute myocardial infarction (AMI) can predict hard cardiac events...
  44. ncbi request reprint Independent value of echocardiography and N-terminal pro-natriuretic Peptide for the prediction of major outcomes in patients with suspected heart failure
    Tiong Keng Lim
    Department of Cardiovascular Medicine and Institute of Postgraduate Medical Education and Research, Northwick Park Hospital, Harrow, United Kingdom
    Am J Cardiol 100:870-5. 2007
    ..1, 95% confidence interval 1.43 to 85.6, p = 0.02). In conclusion, NT-pro-BNP and abnormal echocardiogram provided independent information for predicting adverse outcome in patients with suspected HF referred from the community...
  45. doi request reprint Myocardial contrast echocardiography in ST elevation myocardial infarction: ready for prime time?
    Sajad A Hayat
    Department of Cardiovascular medicine and Institute of Postgraduate Medical and Education Research, Northwick Park Hospital, Watford Road, Harrow HA1 3UJ, UK
    Eur Heart J 29:299-314. 2008
    ..Its portability, rapid acquisition and interpretation of data, and the absence of radiation exposure make it an ideal bedside technique...
  46. ncbi request reprint Influence of isoprostane F2alpha-III on reflow after myocardial infarction
    Kim Greaves
    Department of Cardiology, The Cardiovascular Division, King s College London, St Thomas Hospital, London, UK
    Eur Heart J 25:847-53. 2004
    ..To investigate whether the vasoconstrictor isoprostane F2alpha-III (iPF2alpha-III), released during myocardial reperfusion, contributes to the low/no reflow phenomenon observed following acute myocardial infarction (AMI)...
  47. ncbi request reprint Prognostic value of normal stress echocardiogram in patients with suspected coronary artery disease--a British general hospital experience
    George Chung
    Department of Cardiovascular Medicine, North West London Hospitals NHS Trust and Institute for Medical Research, Northwick Park Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK
    Int J Cardiol 94:181-6. 2004
    ..To determine the prognostic value of a normal stress echocardiogram in the setting of a large district general non-university hospital in the United Kingdom...
  48. ncbi request reprint Community screening for left ventricular hypertrophy in patients with hypertension using hand-held echocardiography
    Roxy Senior
    Department of Cardiovascular Medicine, Northwick Park Hospital, Watford Rd, Harrow, Middlesex, HAI 3UJ United Kingdom
    J Am Soc Echocardiogr 17:56-61. 2004
    ..Thus, hand-held echocardiography devices accurately assessed LVH and may be used for community-based screening for LVH in targeted patients with hypertension...
  49. ncbi request reprint Usefulness of myocardial contrast echocardiography using low-power continuous imaging early after acute myocardial infarction to predict late functional left ventricular recovery
    Rajesh Janardhanan
    Department of Cardiovascular Medicine, Northwick Park Hospital, Harrow, United Kingdom
    Am J Cardiol 92:493-7. 2003
    ..This technique may be utilized to reliably predict late recovery of function in dysfunctional myocardium after AMI...
  50. ncbi request reprint Incremental value of myocardial contrast echocardiography for the prediction of recovery of function in dobutamine nonresponsive myocardium early after acute myocardial infarction
    Roxy Senior
    Department of Cardiovascular Medicine, Northwick Park and St Mark s Hospitals and Institute of Medical Research, Harrow, United Kingdom
    Am J Cardiol 91:397-402. 2003
    ..002) were the only independent predictors of recovery of function. Thus, for optimum prediction of recovery of function after AMI, a combination of DE and MCE in dobutamine nonresponsive segments may be utilized...
  51. ncbi request reprint Midwall myocardial shortening in athletic left ventricular hypertrophy
    Jamil Mayet
    Department of Cardiology, St Mary s Hospital, Praed Street, Paddington, London W2 1NY, UK
    Int J Cardiol 86:233-8. 2002
    ..Whether midwall shortening is depressed in physiological hypertrophy is unknown...
  52. ncbi request reprint Impact of revascularization and myocardial viability determined by nitrate-enhanced Tc-99m sestamibi and Tl-201 imaging on mortality and functional outcome in ischemic cardiomyopathy
    Roxy Senior
    Department of Cardiovascular Medicine, Northwick Park Hospital and Institute of Medical Research, Harrow, United Kingdom
    J Nucl Cardiol 9:454-62. 2002
    ..Nitrate-enhanced perfusion imaging has been shown to detect viability in dysfunctional myocardium, but nitrate-enhanced technetium 99m sestamibi has not been compared with nitrate-enhanced thallium 201...
  53. ncbi request reprint Myocardial contrast echocardiography predicts left ventricular remodelling after acute myocardial infarction
    Paramjit Jeetley
    Department of Cardiovascular Medicine, Northwick Park Hospital, and Institute for Medical Research, London, United Kingdom
    J Am Soc Echocardiogr 17:1030-6. 2004
    ....
  54. ncbi request reprint The clinical applications of contrast echocardiography
    Robert Olszewski
    Cardiac Investigation Annexe, Oxford University, John Radcliffe Hospital, Oxford, UK
    Eur J Echocardiogr 8:S13-23. 2007
    ..Stress echocardiography and regional wall motion assessment. Future echocardiography will be more 3D and more quantitative than current echocardiography. And contrast echocardiography has already proven its value for both applications...
  55. ncbi request reprint The clinical applications of myocardial contrast echocardiography
    Dhrubo J Rakhit
    Department of Cardiology, Northwick Park Hospital, Watford Road, Harrow, UK
    Eur J Echocardiogr 8:S24-9. 2007
    ..Myocardial contrast echocardiography is equally adept in assessing chronic coronary artery disease, acute coronary syndromes and hibernating myocardium...
  56. ncbi request reprint Improved accuracy of low-power contrast echocardiography for the assessment of left ventricular remodeling compared with unenhanced harmonic echocardiography after acute myocardial infarction: comparison with cardiovascular magnetic resonance imaging
    Tiong Keng Lim
    Department of Cardiovascular Medicine, Northwick Park Hospital, Harrow, UK
    J Am Soc Echocardiogr 18:1203-7. 2005
    ..Low-power contrast echocardiography (CE) has the advantage of simultaneously assessing myocardial perfusion and LV remodeling...
  57. ncbi request reprint Clinical benefits of contrast-enhanced echocardiography during rest and stress examinations
    Roxy Senior
    Department of Cardiovascular Medicine, Northwick Park Hospital, Harrow, Middlesex, England, United Kingdom
    Eur J Echocardiogr 6:S6-13. 2005
    ....
  58. ncbi request reprint Clinical significance of perfusion techniques utilising different physiological mechanisms to detect myocardial viability: a comparative study with myocardial contrast echocardiography and single photon emission computed tomography
    Michael Hickman
    Int J Cardiol 114:139-40. 2007
    ..MCE was the only multivariate predictor of global recovery of function and CR (OR=3.5, p=0.01). The different physiological mechanisms employed by MCE and SPECT translate into different relative accuracies for the detection of MV...
  59. ncbi request reprint Accurate assessment of aortic stenosis with intravenous contrast
    Girish Dwivedi
    Department of Cardiology, Northwick Park Hospital, Watford Road, Harrow, Middx HA1 3UJ, United Kingdom
    Eur J Echocardiogr 7:165-7. 2006
    ..Use of contrast in such difficult to image patients is very useful in establishing a correct diagnosis...
  60. pmc A 28 year old postpartum woman with right sided chest discomfort: case outcome
    Girish Dwivedi
    Department of Cardiovascular Medicine, Northwick Park Hospital, Harrow, Middlesex HA1 3UJ
    BMJ 332:643. 2006
  61. pmc Assessing myocardial perfusion after myocardial infarction
    Houman Ashrafian
    Department of Cardiology, Northwick Park Hospital, Harrow, Middlesex, United Kingdom
    PLoS Med 3:e131. 2006
  62. ncbi request reprint Comparison between myocardial contrast echocardiography and single-photon emission computed tomography for predicting transmurality of acute myocardial infarction
    Sajad A Hayat
    Department of Cardiology, Northwick Park Hospital, Harrow, United Kingdom
    Am J Cardiol 97:1718-21. 2006
    ..However, MCE is significantly more accurate in predicting >50% of the transmural extent of infarction and more sensitive in identifying <or=25% of the transmural extent of infarction than SPECT...
  63. ncbi request reprint Myocardial contrast echocardiography: Role in clinical cardiology
    Girish Dwivedi
    Department of Cardiovascular Medicine, Northwick Park Hospital, Harrow, Middlesex, UK
    Curr Vasc Pharmacol 4:229-35. 2006
    ..Furthermore, its use is not limited solely to diagnostic assessment. Preliminary evidence suggests that targeted microbubbles may be useful in enhancing delivery of genes / drugs and in clot lysis...
  64. ncbi request reprint Contrast echocardiography for the assessment of myocardial viability
    Sajad A Hayat
    Department of Cardiology, Northwick Park Hospital, Harrow HA1 3UJ, UK
    Curr Opin Cardiol 21:473-8. 2006
    ..An increasing body of data supports its role in assessing myocardial viability and predicting the recovery of function...
  65. ncbi request reprint Stress echocardiography is superior to exercise ECG in the risk stratification of patients presenting with acute chest pain with negative Troponin
    Paramjit Jeetley
    Department of Cardiovascular Medicine, Northwick Park Hospital and Institute for Medical Research, Watford Road, Harrow, Middlesex HA1 3UJ, UK
    Eur J Echocardiogr 7:155-64. 2006
    ..To compare exercise electrocardiography (ExECG) and stress echocardiography (SE) in the risk stratification of patients presenting to hospital with cardiac-sounding chest pain, non-diagnostic ECGs and negative cardiac Troponin...
  66. ncbi request reprint Myocardial contrast echocardiography accurately reflects transmurality of myocardial necrosis and predicts contractile reserve after acute myocardial infarction
    Rajesh Janardhanan
    Department of Cardiology, Northwick Park Hospital, Harrow, UK
    Am Heart J 149:355-62. 2005
    ..We sought to ascertain the ability of MCE to (1) predict TEI as defined by contrast-enhanced CMR and (2) to compare the relative accuracy of these techniques to predict contractile reserve late after AMI...
  67. ncbi request reprint Myocardial contrast echocardiography evolving as a clinically feasible technique for accurate, rapid, and safe assessment of myocardial perfusion: the evidence so far
    Pieter A Dijkmans
    Department of Cardiology, VU University Medical Center, Amsterdam, The Netherlands
    J Am Coll Cardiol 48:2168-77. 2006
    ..Although MCE has been primarily performed for medical research, its implementation in routine clinical care is evolving. This article is intended to give an overview of the current status of MCE...
  68. ncbi request reprint Clinical and economic impact of stress echocardiography compared with exercise electrocardiography in patients with suspected acute coronary syndrome but negative troponin: a prospective randomized controlled study
    Paramjit Jeetley
    Department of Cardiovascular Medicine, Northwick Park Hospital and Institute for Medical Research, and Health Economics Research Group, Brunel University, Middlesex, UK
    Eur Heart J 28:204-11. 2007
    ..We sought to determine the clinical and economic impact of stress echocardiography (SEcho) when compared with exercise ECG (ExECG) in the assessment of these patients...