- Cleavage and degradation of Claspin during apoptosis by caspases and the proteasomeJ I Semple
Unidad de Investigacion, Hospital Universitario de Canarias Ofra s n, La Cuesta, 38320 La Laguna, Tenerife, Spain
Cell Death Differ 14:1433-42. 2007..We conclude that Claspin has antiapoptotic activity and is degraded by two different pathways during apoptosis. The resulting disappearance of Claspin from the cells further promotes apoptosis...