Jeffrey D Seidman

Summary

Publications

  1. ncbi Primary and metastatic mucinous adenocarcinomas in the ovaries: incidence in routine practice with a new approach to improve intraoperative diagnosis
    Jeffrey D Seidman
    Department of Pathology, Washington Hospital Center, Washington, DC 20010, USA
    Am J Surg Pathol 27:985-93. 2003
  2. ncbi p16 expression in primary ovarian mucinous and endometrioid tumors and metastatic adenocarcinomas in the ovary: utility for identification of metastatic HPV-related endocervical adenocarcinomas
    Russell Vang
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Surg Pathol 31:653-63. 2007
  3. ncbi Immunohistochemical expression of CDX2 in primary ovarian mucinous tumors and metastatic mucinous carcinomas involving the ovary: comparison with CK20 and correlation with coordinate expression of CK7
    Russell Vang
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Mod Pathol 19:1421-8. 2006
  4. doi Endocervical adenocarcinomas with prominent endometrial or endomyometrial involvement simulating primary endometrial carcinomas: utility of HPV DNA detection and immunohistochemical expression of p16 and hormone receptors to confirm the cervical origin of
    Anna Yemelyanova
    Department of Pathology, The Johns Hopkins University School of Medicine and Hospital, Baltimore, MD 21231, USA
    Am J Surg Pathol 33:914-24. 2009
  5. ncbi Testing of two binary grading systems for FIGO stage III serous carcinoma of the ovary and peritoneum
    Jeffrey D Seidman
    Department of Pathology, Washington Hospital Center, Washington, DC 20010, USA
    Gynecol Oncol 103:703-8. 2006
  6. ncbi Ovarian metastases of appendiceal tumors with goblet cell carcinoidlike and signet ring cell patterns: a report of 30 cases
    Alexandra C Hristov
    Department of Pathology, The Johns Hopkins University School of Medicine and Hospital, 401 N Broadway, Baltimore, MD 21231, USA
    Am J Surg Pathol 31:1502-11. 2007
  7. doi Survival rates for international federation of gynecology and obstetrics stage III ovarian carcinoma by cell type: a study of 262 unselected patients with uniform pathologic review
    Jeffrey D Seidman
    Department of Pathology and Laboratory Medicine, Washington Hospital Center, Washington, DC, USA
    Int J Gynecol Cancer 22:367-71. 2012
  8. doi Upstaging pathologic stage I ovarian carcinoma based on dense adhesions is not warranted: a clinicopathologic study of 84 patients originally classified as FIGO stage II
    Jeffrey D Seidman
    Department of Pathology and Laboratory Medicine, Washington Hospital Center, Washington, DC, USA
    Gynecol Oncol 119:250-4. 2010
  9. ncbi Cytokeratins 7 and 20 in primary and secondary mucinous tumors of the ovary: analysis of coordinate immunohistochemical expression profiles and staining distribution in 179 cases
    Russell Vang
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Surg Pathol 30:1130-9. 2006
  10. doi Mucinous metaplasia of the fallopian tube: a diagnostic pitfall mimicking metastasis
    Anna K Wong
    Department of Pathology, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Int J Gynecol Pathol 30:36-40. 2011

Detail Information

Publications35

  1. ncbi Primary and metastatic mucinous adenocarcinomas in the ovaries: incidence in routine practice with a new approach to improve intraoperative diagnosis
    Jeffrey D Seidman
    Department of Pathology, Washington Hospital Center, Washington, DC 20010, USA
    Am J Surg Pathol 27:985-93. 2003
    ..After careful exclusion of noninvasive, microinvasive, and metastatic tumors, pure mucinous adenocarcinoma primary in the ovary appears to be substantially less common than previously reported...
  2. ncbi p16 expression in primary ovarian mucinous and endometrioid tumors and metastatic adenocarcinomas in the ovary: utility for identification of metastatic HPV-related endocervical adenocarcinomas
    Russell Vang
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Surg Pathol 31:653-63. 2007
    ....
  3. ncbi Immunohistochemical expression of CDX2 in primary ovarian mucinous tumors and metastatic mucinous carcinomas involving the ovary: comparison with CK20 and correlation with coordinate expression of CK7
    Russell Vang
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Mod Pathol 19:1421-8. 2006
    ..Cytokeratin 7 provides the predominant discriminatory value among these markers yet is limited to distinction of primary ovarian tumors from metastases of lower gastrointestinal tract origin...
  4. doi Endocervical adenocarcinomas with prominent endometrial or endomyometrial involvement simulating primary endometrial carcinomas: utility of HPV DNA detection and immunohistochemical expression of p16 and hormone receptors to confirm the cervical origin of
    Anna Yemelyanova
    Department of Pathology, The Johns Hopkins University School of Medicine and Hospital, Baltimore, MD 21231, USA
    Am J Surg Pathol 33:914-24. 2009
    ..A subset of misclassified endocervical adenocarcinomas may account for some HPV-positive uterine carcinomas reported as primary endometrial carcinomas...
  5. ncbi Testing of two binary grading systems for FIGO stage III serous carcinoma of the ovary and peritoneum
    Jeffrey D Seidman
    Department of Pathology, Washington Hospital Center, Washington, DC 20010, USA
    Gynecol Oncol 103:703-8. 2006
    ....
  6. ncbi Ovarian metastases of appendiceal tumors with goblet cell carcinoidlike and signet ring cell patterns: a report of 30 cases
    Alexandra C Hristov
    Department of Pathology, The Johns Hopkins University School of Medicine and Hospital, 401 N Broadway, Baltimore, MD 21231, USA
    Am J Surg Pathol 31:1502-11. 2007
    ..In cases in which the primary tumor is not already evident, their "goblet cell carcinoidlike" patterns should direct attention to the appendix as a possible source...
  7. doi Survival rates for international federation of gynecology and obstetrics stage III ovarian carcinoma by cell type: a study of 262 unselected patients with uniform pathologic review
    Jeffrey D Seidman
    Department of Pathology and Laboratory Medicine, Washington Hospital Center, Washington, DC, USA
    Int J Gynecol Cancer 22:367-71. 2012
    ..The recent separation of low-grade serous carcinoma as a distinctive cell type of ovarian cancer with an indolent behavior, in retrospect, suggests that survival in studies that have not separated this group may be inaccurate...
  8. doi Upstaging pathologic stage I ovarian carcinoma based on dense adhesions is not warranted: a clinicopathologic study of 84 patients originally classified as FIGO stage II
    Jeffrey D Seidman
    Department of Pathology and Laboratory Medicine, Washington Hospital Center, Washington, DC, USA
    Gynecol Oncol 119:250-4. 2010
    ..It is a common but not universal practice to upstage densely adherent pathologic stage I tumors to stage II. FIGO guidelines are not clear, and data supporting this practice are sparse...
  9. ncbi Cytokeratins 7 and 20 in primary and secondary mucinous tumors of the ovary: analysis of coordinate immunohistochemical expression profiles and staining distribution in 179 cases
    Russell Vang
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Surg Pathol 30:1130-9. 2006
    ....
  10. doi Mucinous metaplasia of the fallopian tube: a diagnostic pitfall mimicking metastasis
    Anna K Wong
    Department of Pathology, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Int J Gynecol Pathol 30:36-40. 2011
    ..The mucinous changes are frequently seen with chronic inflammation and/or other metaplastic changes and without cytologic evidence of malignancy...
  11. doi The fallopian tube-peritoneal junction: a potential site of carcinogenesis
    Jeffrey D Seidman
    Department of Pathology and Laboratory Medicine, Washington Hospital Center, Washington, DC 20010, USA
    Int J Gynecol Pathol 30:4-11. 2011
    ..This is the first comprehensive description of a hitherto unrecognized transitional zone in the adnexa...
  12. doi "Primary peritoneal" high-grade serous carcinoma is very likely metastatic from serous tubal intraepithelial carcinoma: assessing the new paradigm of ovarian and pelvic serous carcinogenesis and its implications for screening for ovarian cancer
    Jeffrey D Seidman
    Department of Pathology and Laboratory Medicine, Washington Hospital Center, Georgetown University Medical Center, 110 Irving Street, NW, Washington, DC 20010, USA
    Gynecol Oncol 120:470-3. 2011
    ..This study was performed to evaluate this hypothesis in an unselected series of cases...
  13. pmc Defining the cut point between low-grade and high-grade ovarian serous carcinomas: a clinicopathologic and molecular genetic analysis
    Ayse Ayhan
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA
    Am J Surg Pathol 33:1220-4. 2009
    ....
  14. ncbi Mucinous tumors arising in ovarian mature cystic teratomas: relationship to the clinical syndrome of pseudomyxoma peritonei
    Brigitte M Ronnett
    Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland 1231, USA
    Am J Surg Pathol 27:650-7. 2003
    ..Such tumors probably represent the only cases of ovarian origin of PMP...
  15. ncbi Carcinomas of the female genital tract occurring after pelvic irradiation: a report of 15 cases
    Jeffrey D Seidman
    Department of Pathology, Washington Hospital Center, Washington, DC 20010, USA
    Int J Gynecol Pathol 25:293-7. 2006
    ..Gynecological carcinomas may occur many years after pelvic irradiation. Although the evidence for a causative role is circumstantial, these tumors appear to have a similar latent period as postradiation sarcomas...
  16. ncbi Cytokeratins 7 and 20, Dpc4, and MUC5AC in the distinction of metastatic mucinous carcinomas in the ovary from primary ovarian mucinous tumors: Dpc4 assists in identifying metastatic pancreatic carcinomas
    Hongxiu Ji
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore 21231, USA
    Int J Gynecol Pathol 21:391-400. 2002
    ..Loss of Dpc4 expression is useful for distinguishing metastatic pancreatic carcinomas in the ovary from both primary ovarian mucinous tumors and metastatic mucinous carcinomas derived from other sites...
  17. ncbi Pathology of borderline (low malignant potential) ovarian tumours
    Jeffrey D Seidman
    Department of Pathology, Washington Hospital Center, Washington, DC 20010, USA
    Best Pract Res Clin Obstet Gynaecol 16:499-512. 2002
    ..The remaining mucinous borderline tumours are always confined to the ovaries and have a benign behaviour. Since borderline tumours can now be classified into benign and malignant types, the category has no further utility...
  18. ncbi Borderline ovarian tumors: key points and workshop summary
    Steven G Silverberg
    Department of Pathology, University of Maryland School of Medicine, Baltimore 21201, USA
    Hum Pathol 35:910-7. 2004
    ....
  19. ncbi The histologic type and stage distribution of ovarian carcinomas of surface epithelial origin
    Jeffrey D Seidman
    Department of Pathology, Washington Hospital Center, Washington, DC 20010, USA
    Int J Gynecol Pathol 23:41-4. 2004
    ....
  20. doi The pathogenesis of atypical proliferative Brenner tumor: an immunohistochemical and molecular genetic analysis
    Elisabetta Kuhn
    Department of Pathology, Johns Hopkins Medical Institutions, Johns Hopkins University, Baltimore, MD, USA
    Mod Pathol 27:231-7. 2014
    ..In summary, our findings suggest that loss of CDKN2A and, to a lesser extent, KRAS and PIK3CA somatic mutations have a role in the progression of a benign to an atypical proliferative Brenner tumor. ..
  21. ncbi Borderline ovarian tumors: diverse contemporary viewpoints on terminology and diagnostic criteria with illustrative images
    Jeffrey D Seidman
    Department of Pathology, Washington Hospital Center, Washington DC 20010, USA
    Hum Pathol 35:918-33. 2004
    ..For those issues where there is disagreement, the terminology and diagnostic approaches reflecting the differing views are presented...
  22. doi The relationship between papillary infarction and microinvasion in ovarian atypical proliferative ("borderline") serous and seromucinous tumors
    James A Kraus
    Department of Pathology and Laboratory Medicine, Washington Hospital Center, Washington, DC, USA
    Int J Gynecol Pathol 29:303-9. 2010
    ..APSTs with microinvasion are more common than earlier appreciated. Whether papillary infarction is pathogenetically related to microinvasion is unknown and warrants further investigation...
  23. ncbi Pathology of ovarian carcinoma
    Jeffrey D Seidman
    Department of Pathology, Washington Hospital Center, 110 Irving Street, Northwest, Washington, DC 20010, USA
    Hematol Oncol Clin North Am 17:909-25, vii. 2003
    ..Micropapillary serous carcinomas (a less common variant, also called serous borderline tumor with a micropapillary pattern) and tumors with invasive implants behave similar to low-grade invasive carcinomas...
  24. doi Ovarian and paraovarian squamous-lined cysts (epidermoid cysts): a clinicopathologic study of 18 cases with comparison to mature cystic teratomas
    Fatemeh Khedmati
    Department of Pathology and Laboratory Medicine, Washington Hospital Center, Washington, DC 20010, USA
    Int J Gynecol Pathol 28:193-6. 2009
    ..Epidermoid cyst of the ovary as defined by histology is a heterogeneous group; pure epidermoid cyst, if it exists at all, probably represents less than 1% of ovarian surface epithelial tumors...
  25. doi Exploring the histogenesis of ovarian mucinous and transitional cell (Brenner) neoplasms and their relationship with Walthard cell nests: a study of 120 tumors
    Jeffrey D Seidman
    Department of Pathology, Washington Hospital Center, 110 Irving St, NW, Washington, DC 20010, USA
    Arch Pathol Lab Med 132:1753-60. 2008
    ..The origin of and relationship between ovarian mucinous and transitional cell (Brenner) neoplasms are enigmatic. The reported association ranges from 1% to 16%, and whether there is an association with Walthard cell nests is unknown...
  26. ncbi Sustained response to bevacizumab in refractory well-differentiated ovarian neoplasms
    Michael A Bidus
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Walter Reed Army Medical Center, 6900 Georgia Avenue NW, Washington, DC 20307, USA
    Gynecol Oncol 102:5-7. 2006
    ..Bevacizumab has demonstrated activity against a variety of solid tumors, including ovarian carcinoma. However, there have not been reproducible prognostic features associated with its activity...
  27. ncbi Interobserver and intraobserver variability of a two-tier system for grading ovarian serous carcinoma
    Anais Malpica
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Am J Surg Pathol 31:1168-74. 2007
    ....
  28. ncbi Evaluation of normal-sized ovaries associated with primary peritoneal serous carcinoma for possible precursors of ovarian serous carcinoma
    Jeffrey D Seidman
    Department of Pathology and Laboratory Medicine, Washington Hospital Center, Washington, DC 20010, USA
    Gynecol Oncol 106:201-6. 2007
    ..No data are available for a fourth high-risk group: normal-sized ovaries from women with primary peritoneal serous carcinoma...
  29. ncbi Benign ovarian serous tumors: a re-evaluation and proposed reclassification of serous "cystadenomas" and "cystadenofibromas"
    Jeffrey D Seidman
    Department of Pathology, Washington Hospital Center, 110 Irving Street N W, Washington, DC 20010, USA
    Gynecol Oncol 96:395-401. 2005
    ....
  30. ncbi Uterine lipoleiomyomas: a clinicopathologic study of 50 cases
    Xiaotong Wang
    Department of Pathology and Laboratory Medicine, Washington Hospital Center, Washington, DC 20010, USA
    Int J Gynecol Pathol 25:239-42. 2006
    ..0 years). Four patients died of unrelated causes. There were no recurrences or fatalities related to tumor. Lipoleiomyoma of the uterus seems to have an uneventful clinical course and can now be confidently regarded as benign...
  31. ncbi Clinicopathological analysis of c-kit expression in carcinosarcomas and leiomyosarcomas of the uterine corpus
    William E Winter
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Walter Reed Army Medical Center, Washington, DC 20307, USA
    Gynecol Oncol 91:3-8. 2003
    ....
  32. ncbi Salpingitis, salpingoliths, and serous tumors of the ovaries: is there a connection?
    Jeffrey D Seidman
    Department of Pathology, Washington Hospital Center, Washington, DC 20010, USA
    Int J Gynecol Pathol 21:101-7. 2002
    ..In addition, the high frequency of salpingitis in women with endometriosis may be related to the mechanism of endometriosis-associated infertility...
  33. ncbi Treatment of micropapillary serous ovarian carcinoma (the aggressive variant of serous borderline tumors)
    Jeffrey D Seidman
    Cancer 95:675-6. 2002
  34. ncbi Osteopontin as a biomarker for ovarian cancer
    Jeffrey D Seidman
    JAMA 287:3209; author reply 3209-10. 2002
  35. ncbi Current challenges and opportunities for research on borderline ovarian tumors
    Mark E Sherman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, USA
    Hum Pathol 35:961-70. 2004
    ....