- Design, power, and interpretation of studies in the standard murine model of ALSSean Scott
ALS Therapy Development Institute, Cambridge, Massachusetts 02142, USA
Amyotroph Lateral Scler 9:4-15. 2008..We recommend a minimum study design for this mouse model to best address and manage this inherent noise and to facilitate more significant and reproducible results among all laboratories employing the SOD1(G93A) mouse...
- Guidelines for the preclinical in vivo evaluation of pharmacological active drugs for ALS/MND: report on the 142nd ENMC international workshopAlbert C Ludolph
Department of Neurology, University of Ulm, Ulm, Germany
Amyotroph Lateral Scler 8:217-23. 2007..In this workshop, clinical and preclinical researchers established in the field of ALS/MND met in Holland in March 2006 in order to establish guidelines for the community for drug testing in mouse models...