J Anthony G Scott

Summary

Publications

  1. pmc Pneumonia research to reduce childhood mortality in the developing world
    J Anthony G Scott
    Wellcome Trust KEMRI Research Programme, Kilifi, Kenya
    J Clin Invest 118:1291-300. 2008
  2. pmc Phenotypic, genomic, and transcriptional characterization of Streptococcus pneumoniae interacting with human pharyngeal cells
    Sheila Z Kimaro Mlacha
    Kenya Medical Research Institute, Wellcome Trust Research Programme, Kilifi, Kenya
    BMC Genomics 14:383. 2013
  3. ncbi Incidence of convulsive epilepsy in a rural area in Kenya
    Anthony K Ngugi
    KEMRI Wellcome Trust Research Programme, Centre for Geographic Medicine Research Coast, Kilifi, Kenya
    Epilepsia 54:1352-9. 2013
  4. pmc Rates of acquisition and clearance of pneumococcal serotypes in the nasopharynges of children in Kilifi District, Kenya
    Osman Abdullahi
    Kenya Medical Research Institute Wellcome Trust Research Programme, Kilifi, Kenya
    J Infect Dis 206:1020-9. 2012
  5. pmc Severe lower respiratory tract infection in early infancy and pneumonia hospitalizations among children, Kenya
    Patrick Kiio Munywoki
    KEMRI Wellcome Trust Research Programme Centre for Geographic Medicine Research Coast, Kilifi, Kenya
    Emerg Infect Dis 19:223-9. 2013
  6. pmc Transcriptional adaptation of pneumococci and human pharyngeal cells in the presence of a virus infection
    Sheila Z Kimaro Mlacha
    Kenya Medical Research Institute, Wellcome Trust Research Programme, Kilifi, Kenya
    BMC Genomics 14:378. 2013
  7. pmc Influenza surveillance among children with pneumonia admitted to a district hospital in coastal Kenya, 2007-2010
    Clayton O Onyango
    KEMRI Wellcome Trust Research Programme, Kilifi District Hospital, Kilifi, Kenya
    J Infect Dis 206:S61-7. 2012
  8. pmc Profile: The Kilifi Health and Demographic Surveillance System (KHDSS)
    J Anthony G Scott
    Kenya Medical Research Institute, Wellcome Trust Research Programme, Kilifi, Kenya
    Int J Epidemiol 41:650-7. 2012
  9. pmc The definition of pneumonia, the assessment of severity, and clinical standardization in the Pneumonia Etiology Research for Child Health study
    J Anthony G Scott
    KEMRI Wellcome Trust Research Programme, Kilifi, Kenya
    Clin Infect Dis 54:S109-16. 2012
  10. pmc Viral etiology of severe pneumonia among Kenyan infants and children
    James A Berkley
    Kenya Medical Research Institute, Centre for Geographic Medicine Research Coast, Kilifi, Kenya
    JAMA 303:2051-7. 2010

Collaborators

Detail Information

Publications17

  1. pmc Pneumonia research to reduce childhood mortality in the developing world
    J Anthony G Scott
    Wellcome Trust KEMRI Research Programme, Kilifi, Kenya
    J Clin Invest 118:1291-300. 2008
    ..However, as we highlight here, there are critical gaps in our understanding of the epidemiology, etiology, and pathophysiology of pneumonia that, if filled, could accelerate the control of pneumonia and reduce early childhood mortality...
  2. pmc Phenotypic, genomic, and transcriptional characterization of Streptococcus pneumoniae interacting with human pharyngeal cells
    Sheila Z Kimaro Mlacha
    Kenya Medical Research Institute, Wellcome Trust Research Programme, Kilifi, Kenya
    BMC Genomics 14:383. 2013
    ..Understanding the molecular interactions between the bacterium and the host will contribute to the control and prevention of pneumococcal disease...
  3. ncbi Incidence of convulsive epilepsy in a rural area in Kenya
    Anthony K Ngugi
    KEMRI Wellcome Trust Research Programme, Centre for Geographic Medicine Research Coast, Kilifi, Kenya
    Epilepsia 54:1352-9. 2013
    ..We determined the incidence of convulsive epilepsy (CE) in a large rural population in Kenya...
  4. pmc Rates of acquisition and clearance of pneumococcal serotypes in the nasopharynges of children in Kilifi District, Kenya
    Osman Abdullahi
    Kenya Medical Research Institute Wellcome Trust Research Programme, Kilifi, Kenya
    J Infect Dis 206:1020-9. 2012
    ..We estimated serotype-specific clearance and acquisition rates of nasopharyngeal colonization among Kenyan children...
  5. pmc Severe lower respiratory tract infection in early infancy and pneumonia hospitalizations among children, Kenya
    Patrick Kiio Munywoki
    KEMRI Wellcome Trust Research Programme Centre for Geographic Medicine Research Coast, Kilifi, Kenya
    Emerg Infect Dis 19:223-9. 2013
    ..Excess pneumonia risk persisted for 2 years after the initial hospitalization. Close postdischarge follow-up of infants with LRTI, with or without RSV, could help prevent severe pneumonia later in childhood...
  6. pmc Transcriptional adaptation of pneumococci and human pharyngeal cells in the presence of a virus infection
    Sheila Z Kimaro Mlacha
    Kenya Medical Research Institute, Wellcome Trust Research Programme, Kilifi, Kenya
    BMC Genomics 14:378. 2013
    ..The objective of this study is to describe a comprehensive picture of the cellular interaction between the adhering bacteria and host cells in the presence or absence of a viral co-infection...
  7. pmc Influenza surveillance among children with pneumonia admitted to a district hospital in coastal Kenya, 2007-2010
    Clayton O Onyango
    KEMRI Wellcome Trust Research Programme, Kilifi District Hospital, Kilifi, Kenya
    J Infect Dis 206:S61-7. 2012
    ..Influenza data gaps in sub-Saharan Africa include incidence, case fatality, seasonal patterns, and associations with prevalent disorders...
  8. pmc Profile: The Kilifi Health and Demographic Surveillance System (KHDSS)
    J Anthony G Scott
    Kenya Medical Research Institute, Wellcome Trust Research Programme, Kilifi, Kenya
    Int J Epidemiol 41:650-7. 2012
    ..Rapport with residents is maintained through an active programme of community engagement. A system of collaborative engagement exists for sharing data on survival, morbidity, socio-economic status and vaccine coverage...
  9. pmc The definition of pneumonia, the assessment of severity, and clinical standardization in the Pneumonia Etiology Research for Child Health study
    J Anthony G Scott
    KEMRI Wellcome Trust Research Programme, Kilifi, Kenya
    Clin Infect Dis 54:S109-16. 2012
    ..These will be maintained by a clinical standardization monitor who conducts repeated instruction at each site and by recurrent local training and testing...
  10. pmc Viral etiology of severe pneumonia among Kenyan infants and children
    James A Berkley
    Kenya Medical Research Institute, Centre for Geographic Medicine Research Coast, Kilifi, Kenya
    JAMA 303:2051-7. 2010
    ..Pneumonia is the leading cause of childhood death in sub-Saharan Africa. Comparative estimates of the contribution of causative pathogens to the burden of disease are essential for targeted vaccine development...
  11. pmc The global epidemiology of childhood pneumonia 20 years on
    J Anthony G Scott
    KEMRI Wellcome Trust Collaborative Research Programme, Centre for Geographic Medicine Research, Kilifi, Kenya
    Bull World Health Organ 86:494-6. 2008
  12. pmc The descriptive epidemiology of Streptococcus pneumoniae and Haemophilus influenzae nasopharyngeal carriage in children and adults in Kilifi district, Kenya
    Osman Abdullahi
    Wellcome Trust Kenya Medical Research Institute, Centre for Geographic Medicine Research Coast, Kilifi, Kenya
    Pediatr Infect Dis J 27:59-64. 2008
    ..In East Africa we do not know how these pathogens are transmitted between population subgroups nor which serotypes circulate commonly...
  13. pmc Validation of nasopharyngeal sampling and culture techniques for detection of Streptococcus pneumoniae in children in Kenya
    Osman Abdullahi
    Kenya Medical Research Institute Wellcome Trust Research Program, Centre for Geographic Medicine Research Coast, P O Box 230, Kilifi, Kenya
    J Clin Microbiol 45:3408-10. 2007
    ..Among the 55 children with positive nasal wash cultures, swab cultures were positive for 47 (85%). Of the 96 swabs positive on direct plating, 94 (98%) were positive when recultured after freezing...
  14. pmc Diagnosis of invasive pneumococcal disease among children in Kenya with enzyme-linked immunosorbent assay for immunoglobulin G antibodies to pneumococcal surface adhesin A
    J Anthony G Scott
    Wellcome Trust KEMRI Centre for Geographic Medicine Research Coast, P O Box 230, Kilifi, Kenya
    Clin Diagn Lab Immunol 12:1195-201. 2005
    ..Effective diagnosis of pneumococcal disease in children is urgently required but poorly served by existing technology...
  15. pmc Diagnosis of pneumococcal pneumonia by psaA PCR analysis of lung aspirates from adult patients in Kenya
    J Anthony G Scott
    Wellcome Trust Kenya Medical Research Institute, Centre for Geographic Medicine Research Coast, Kilifi, Kenya
    J Clin Microbiol 41:2554-9. 2003
    ..psaA PCR analysis is a sensitive tool for diagnosis of pneumococcal pneumonia in adults...
  16. ncbi Validation of immunoglobulin G enzyme-linked immunosorbent assay for antibodies to pneumococcal surface adhesin A in the diagnosis of pneumococcal pneumonia among adults in Kenya
    J Anthony G Scott
    Wellcome Trust Kenya Medical Research Institute, Centre for Geographic Medicine Research Coast, Kilifi, Kenya
    J Infect Dis 186:220-6. 2002
    ..The combination of high sensitivity and high specificity makes this an ideal assay for epidemiologic studies of pneumococcal pneumonia...
  17. pmc Age-specific immunoglobulin g (IgG) and IgA to pneumococcal protein antigens in a population in coastal kenya
    Catherine Laine
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Infect Immun 72:3331-5. 2004
    ..001). No decline was observed in the sera of the elderly. Anti-protein IgG concentrations were only weakly correlated (0.30 < r < 0.56; P < 0.0001), as were IgA concentrations (0.24 < r < 0.54; P < 0.0001)...