Gary G Schwartz

Summary

Publications

  1. ncbi request reprint Vitamin d in blood and risk of prostate cancer: lessons from the selenium and vitamin e cancer prevention trial and the prostate cancer prevention trial
    Gary G Schwartz
    Departments of Cancer Biology, Urology, and Epidemiology and Prevention, Wake Forest University School of Medicine, Winston Salem, North Carolina
    Cancer Epidemiol Biomarkers Prev 23:1447-9. 2014
  2. doi request reprint Prospective studies of total and ionized serum calcium in relation to incident and fatal ovarian cancer
    Gary G Schwartz
    Department of Cancer Biology, Wake Forest School of Medicine, Winston Salem, NC, USA
    Gynecol Oncol 129:169-72. 2013
  3. ncbi request reprint Vitamin D, sunlight, and the epidemiology of prostate cancer
    Gary G Schwartz
    Comprehensive Cancer Center of Wake Forest University, Medical Center Blvd, Winston Salem, NC 27157, USA
    Anticancer Agents Med Chem 13:45-57. 2013
  4. pmc Low 25-hydroxyvitamin D predicts the onset of mobility limitation and disability in community-dwelling older adults: the Health ABC Study
    Denise K Houston
    Department of Internal Medicine, Wake Forest School of Medicine, Winston Salem, North Carolina 27157 1207, USA
    J Gerontol A Biol Sci Med Sci 68:181-7. 2013
  5. pmc 25-hydroxyvitamin D status and change in physical performance and strength in older adults: the Health, Aging, and Body Composition Study
    Denise K Houston
    Department of Internal Medicine, Wake Forest School of Medicine, Winston Salem, North Carolina 27157 1207, USA
    Am J Epidemiol 176:1025-34. 2012
  6. pmc Calcium and vitamin D supplementation and loss of bone mineral density in women undergoing breast cancer therapy
    Mridul Datta
    Department of Social Sciences and Health Policy, Wake Forest School of Medicine, Winston Salem, NC, USA
    Crit Rev Oncol Hematol 88:613-24. 2013
  7. pmc 25-Hydroxyvitamin D, parathyroid hormone, and mortality in black and white older adults: the health ABC study
    Stephen B Kritchevsky
    Sticht Center on Aging, Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Medical Center Boulevard, Winston Salem, North Carolina 27157 1207, USA
    J Clin Endocrinol Metab 97:4156-65. 2012
  8. doi request reprint A prospective study of total and ionized serum calcium and time to fatal prostate cancer
    Gary G Schwartz
    Department of Cancer Biology, Wake Forest Baptist Medical Center, Winston Salem, North Carolina, USA
    Cancer Epidemiol Biomarkers Prev 21:1768-73. 2012
  9. ncbi request reprint The 'cocaine blues' and other problems in epidemiologic studies of vitamin D and cancer
    Gary G Schwartz
    Department of Cancer Biology Wake Forest University, Medical Center Blvd, Winston Salem, NC 27157, USA
    Nutr Rev 65:S75-6. 2007
  10. pmc Serum parathyroid hormone levels predict falls in older adults with diabetes mellitus
    Denise K Houston
    Sticht Center on Aging, Wake Forest University, Winston Salem, North Carolina, USA
    J Am Geriatr Soc 56:2027-32. 2008

Detail Information

Publications21

  1. ncbi request reprint Vitamin d in blood and risk of prostate cancer: lessons from the selenium and vitamin e cancer prevention trial and the prostate cancer prevention trial
    Gary G Schwartz
    Departments of Cancer Biology, Urology, and Epidemiology and Prevention, Wake Forest University School of Medicine, Winston Salem, North Carolina
    Cancer Epidemiol Biomarkers Prev 23:1447-9. 2014
    ..The results from these large prevention trials support the hypothesis that circulating levels of 25-OHD decrease the risk of clinically relevant prostate cancers. Cancer Epidemiol Biomarkers Prev; 23(8); 1447-9. ©2014 AACR. ..
  2. doi request reprint Prospective studies of total and ionized serum calcium in relation to incident and fatal ovarian cancer
    Gary G Schwartz
    Department of Cancer Biology, Wake Forest School of Medicine, Winston Salem, NC, USA
    Gynecol Oncol 129:169-72. 2013
    ..Many ovarian cancers express parathyroid hormone-related protein, which acts to raise calcium levels in serum. Thus, we hypothesized that high serum calcium levels might predict ovarian cancer...
  3. ncbi request reprint Vitamin D, sunlight, and the epidemiology of prostate cancer
    Gary G Schwartz
    Comprehensive Cancer Center of Wake Forest University, Medical Center Blvd, Winston Salem, NC 27157, USA
    Anticancer Agents Med Chem 13:45-57. 2013
    ..The relationship between serum 25(OH)D levels and risk of prostate cancer may differ by calcium intake...
  4. pmc Low 25-hydroxyvitamin D predicts the onset of mobility limitation and disability in community-dwelling older adults: the Health ABC Study
    Denise K Houston
    Department of Internal Medicine, Wake Forest School of Medicine, Winston Salem, North Carolina 27157 1207, USA
    J Gerontol A Biol Sci Med Sci 68:181-7. 2013
    ....
  5. pmc 25-hydroxyvitamin D status and change in physical performance and strength in older adults: the Health, Aging, and Body Composition Study
    Denise K Houston
    Department of Internal Medicine, Wake Forest School of Medicine, Winston Salem, North Carolina 27157 1207, USA
    Am J Epidemiol 176:1025-34. 2012
    ..Older adults with low 25(OH)D concentrations had poorer physical performance over 4 years of follow-up, but low 25(OH)D concentrations were not associated with a faster rate of decline in physical performance or strength...
  6. pmc Calcium and vitamin D supplementation and loss of bone mineral density in women undergoing breast cancer therapy
    Mridul Datta
    Department of Social Sciences and Health Policy, Wake Forest School of Medicine, Winston Salem, NC, USA
    Crit Rev Oncol Hematol 88:613-24. 2013
    ..Because calcium supplements may increase cardiovascular disease risk, future trials should evaluate the safety and efficacy of Ca±D supplementation in women undergoing breast cancer therapy...
  7. pmc 25-Hydroxyvitamin D, parathyroid hormone, and mortality in black and white older adults: the health ABC study
    Stephen B Kritchevsky
    Sticht Center on Aging, Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Medical Center Boulevard, Winston Salem, North Carolina 27157 1207, USA
    J Clin Endocrinol Metab 97:4156-65. 2012
    ..Whether the relationship is similar in Blacks and to what extent differences in 25(OH)D explain racial disparities in mortality is unclear...
  8. doi request reprint A prospective study of total and ionized serum calcium and time to fatal prostate cancer
    Gary G Schwartz
    Department of Cancer Biology, Wake Forest Baptist Medical Center, Winston Salem, North Carolina, USA
    Cancer Epidemiol Biomarkers Prev 21:1768-73. 2012
    ..If this were true, prostate cancer mortality rates among men with higher levels of serum calcium should be higher during the early follow-up period and should decline thereafter...
  9. ncbi request reprint The 'cocaine blues' and other problems in epidemiologic studies of vitamin D and cancer
    Gary G Schwartz
    Department of Cancer Biology Wake Forest University, Medical Center Blvd, Winston Salem, NC 27157, USA
    Nutr Rev 65:S75-6. 2007
  10. pmc Serum parathyroid hormone levels predict falls in older adults with diabetes mellitus
    Denise K Houston
    Sticht Center on Aging, Wake Forest University, Winston Salem, North Carolina, USA
    J Am Geriatr Soc 56:2027-32. 2008
    ..To examine the association between serum parathyroid hormone (PTH) levels and incident falls in older adults with diabetes mellitus...
  11. doi request reprint Vitamin D and intervention trials in prostate cancer: from theory to therapy
    Gary G Schwartz
    Departments of Cancer Biology and Epidemiology and Prevention, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Ann Epidemiol 19:96-102. 2009
    ..Once merely a promise, vitamin D-based therapies for prostate cancer may soon be medical practice...
  12. ncbi request reprint Phase I/II study of 19-nor-1alpha-25-dihydroxyvitamin D2 (paricalcitol) in advanced, androgen-insensitive prostate cancer
    Gary G Schwartz
    Department of Cancer Biology, Wake Forest University, Winston Salem, NC 27157, and Nortwest Georgia Oncology Centers, Douglasville, USA
    Clin Cancer Res 11:8680-5. 2005
    ..We assessed the safety and efficacy of the vitamin D analogue, 19-nor-1alpha-25-dihydroxyvitamin D2 (paricalcitol), in patients with androgen-independent prostate cancer...
  13. pmc Association between vitamin D status and physical performance: the InCHIANTI study
    Denise K Houston
    Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    J Gerontol A Biol Sci Med Sci 62:440-6. 2007
    ..Vitamin D status has been hypothesized to play a role in musculoskeletal function. Using data from the InCHIANTI study, we examined the association between vitamin D status and physical performance...
  14. ncbi request reprint UV, latitude, and spatial trends in prostate cancer mortality: all sunlight is not the same (United States)
    Gary G Schwartz
    Department of Cancer Biology, Wake Forest University, Winston Salem, NC, USA
    Cancer Causes Control 17:1091-101. 2006
    ..Furthermore, because vitamin D synthesis does not occur during winter months at latitudes higher than 40 degrees N, we examined this relationship above and below 40 degrees N latitude...
  15. pmc Oral paricalcitol (19-nor-1,25-dihydroxyvitamin D2) in women receiving chemotherapy for metastatic breast cancer: a feasibility trial
    Julia A Lawrence
    Wake Forest University Comprehensive Cancer Center, Winston Salem, NC, USA
    Cancer Biol Ther 14:476-80. 2013
    ..4 ± 40.9 pg/ml) vs. 46.2 ± 20.3 pg/ml (p = 0 0.001) (iPTH reference 12-72 pg/ml). We conclude that paricalcitol is safe and feasible in women with MBC who are receiving chemotherapy...
  16. pmc Calcium and vitamin D supplementation during androgen deprivation therapy for prostate cancer: a critical review
    Mridul Datta
    Wake Forest Baptist Medical Center, Departments of Cancer Biology, Urology, and Epidemiology and Prevention, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Oncologist 17:1171-9. 2012
    ..Supplementation with calcium and/or vitamin D in these men seems logical and is advocated by many lay and professional groups...
  17. ncbi request reprint Vitamin D and the epidemiology of prostate cancer
    Gary G Schwartz
    Comprehensive Cancer Center, Wake Forest University, Winston Salem, North Carolina 27157, USA
    Semin Dial 18:276-89. 2005
    ..In both diseases, ecologic observations about UV radiation preceded experimental observations and were subsequently validated by them...
  18. doi request reprint Prostate cancer, serum parathyroid hormone, and the progression of skeletal metastases
    Gary G Schwartz
    Departments of Cancer Biology and Epidemiology and Prevention, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
    Cancer Epidemiol Biomarkers Prev 17:478-83. 2008
    ..In particular, we propose that suppressing serum PTH in advanced prostate cancer may reduce morbidity by decreasing fractures and pain caused by bone resorption and may reduce mortality by retarding the progression of metastatic disease...
  19. ncbi request reprint Vitamin D status and cancer: new insights
    Gary G Schwartz
    Departments of Cancer Biology and Epidemiology and Prevention, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Curr Opin Clin Nutr Metab Care 10:6-11. 2007
    ..The aim of this article is to describe recent developments in human studies of the role of vitamin D in the etiology and treatment of cancer...
  20. ncbi request reprint 19-nor-1 alpha,25-dihydroxyvitamin D2 (paricalcitol) inhibits the proliferation of human pancreatic cancer cells in vitro and in vivo
    Gary G Schwartz
    Department of Cancer Biology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Cancer Biol Ther 7:430-6. 2008
    ..Tumor inhibition was accompanied by in vivo upregulation of p21 and p27 expression. Given the few therapeutic options for patients with pancreatic cancer, further exploration of paricalcitol, an FDA-approved medication, is warranted...
  21. ncbi request reprint Prostate cancer in African-American men and polymorphism in the calcium-sensing receptor
    Gary G Schwartz
    Wake Forest University Health Sciences, Department of Cancer Biology, Winston Salem, NC, USA
    Cancer Biol Ther 9:994-9. 2010
    ..This is the first study of CaSR polymorphisms and risk of prostate cancer...