Geert Mayer

Summary

Affiliation: Hephata Klinik
Country: Schwalmstadt-Treysa

Publications

  1. ncbi request reprint Narcolepsy increased L-PGDS (beta-trace) levels correlate with excessive daytime sleepiness but not with cataplexy
    Wolfgang Jordan
    Dept of Psychiatry and Psychotherapy, Georg August University of Gottingen, von Sieboldstr 5, 37075 Gottingen, Germany
    J Neurol 252:1372-8. 2005
  2. pmc Efficacy and safety of 6-month nightly ramelteon administration in adults with chronic primary insomnia
    Geert Mayer
    Hephata Klinik, Schwalmstadt, Germany
    Sleep 32:351-60. 2009
  3. doi request reprint [Narcolepsy]
    G Mayer
    Klinik fur Neurologie, Hephata Klinik, Philipps Universitat Marburg, Schimmelpfengstr 6, 34613, Schwalmstadt Treysa, Deutschland
    Nervenarzt 85:26, 28-34. 2014
  4. doi request reprint [The Kleine-Levin syndrome: new aspects of a rare disease]
    G Mayer
    Hephata Klinik, Schimmelpfengstr 6, Schwalmstadt Treysa, Deutschland
    Nervenarzt 84:1207-12. 2013
  5. doi request reprint The use of sodium oxybate to treat narcolepsy
    Geert Mayer
    Hephata Klinik, Schimmelpfengstr 2, 34613 Schwalmstadt Treysa, Germany
    Expert Rev Neurother 12:519-29. 2012
  6. doi request reprint [Frequently occurring sleep disorders]
    G Mayer
    Hephata Klinik Schwalmstadt Treysa, Schwalmstadt Treysa, Germany
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 54:1284-95. 2011
  7. doi request reprint Insomnia in central neurologic diseases--occurrence and management
    Geert Mayer
    Hephata Klinik, Schwalmstadt Treysa, Germany
    Sleep Med Rev 15:369-78. 2011
  8. doi request reprint Quantification of tonic and phasic muscle activity in REM sleep behavior disorder
    Geert Mayer
    Department of Neurology, Hephata Klinik, Schwalmstadt Treysa, Germany
    J Clin Neurophysiol 25:48-55. 2008
  9. ncbi request reprint Sleep related rhythmic movement disorder revisited
    Geert Mayer
    Hephata Klinik, Department of Neurology, Schwalmstadt, Germany
    J Sleep Res 16:110-6. 2007
  10. ncbi request reprint [The neurophysiology of cataplexy]
    G Mayer
    Hephata Klinik, Schwalmstadt Treysa
    Nervenarzt 76:1464, 1466-9. 2005

Detail Information

Publications31

  1. ncbi request reprint Narcolepsy increased L-PGDS (beta-trace) levels correlate with excessive daytime sleepiness but not with cataplexy
    Wolfgang Jordan
    Dept of Psychiatry and Psychotherapy, Georg August University of Gottingen, von Sieboldstr 5, 37075 Gottingen, Germany
    J Neurol 252:1372-8. 2005
    ..The recently demonstrated involvement of the leptomeningeal lipocalin-type prostaglandin-Dsynthase (L-PGDS) (beta-trace) in human physiological sleep encouraged us to investigate its role in the pathophysiology of narcolepsy...
  2. pmc Efficacy and safety of 6-month nightly ramelteon administration in adults with chronic primary insomnia
    Geert Mayer
    Hephata Klinik, Schwalmstadt, Germany
    Sleep 32:351-60. 2009
    ..Long-duration (> or = 6 months) polysomnographic studies of insomnia medications are lacking. This study evaluated the long-term efficacy of ramelteon, a selective MT1/MT2 melatonin-receptor agonist used for insomnia treatment...
  3. doi request reprint [Narcolepsy]
    G Mayer
    Klinik fur Neurologie, Hephata Klinik, Philipps Universitat Marburg, Schimmelpfengstr 6, 34613, Schwalmstadt Treysa, Deutschland
    Nervenarzt 85:26, 28-34. 2014
    ..Early diagnosis of narcolepsy has the possibility to offer affected persons an adequate medication to lead an almost normal life and the future possibility to cure narcolepsy through immunomodulation therapy...
  4. doi request reprint [The Kleine-Levin syndrome: new aspects of a rare disease]
    G Mayer
    Hephata Klinik, Schimmelpfengstr 6, Schwalmstadt Treysa, Deutschland
    Nervenarzt 84:1207-12. 2013
    ..Lithium reduces the frequency and duration of symptomatic phases. Assuming that KLS is underdiagnosed it should be considered as a differential diagnosis in young patients with recurrent hypersomnia...
  5. doi request reprint The use of sodium oxybate to treat narcolepsy
    Geert Mayer
    Hephata Klinik, Schimmelpfengstr 2, 34613 Schwalmstadt Treysa, Germany
    Expert Rev Neurother 12:519-29. 2012
    ..This article gives an overview of sodium oxybate, which has been US FDA approved for the treatment of cataplexy and excessive daytime sleepiness in patients with narcolepsy, and EMA approved for the treatment of narcolepsy-cataplexy...
  6. doi request reprint [Frequently occurring sleep disorders]
    G Mayer
    Hephata Klinik Schwalmstadt Treysa, Schwalmstadt Treysa, Germany
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 54:1284-95. 2011
    ..The levels of evidence were given according to the recommendations of the Oxford Centre for Evidence-based Medicine...
  7. doi request reprint Insomnia in central neurologic diseases--occurrence and management
    Geert Mayer
    Hephata Klinik, Schwalmstadt Treysa, Germany
    Sleep Med Rev 15:369-78. 2011
    ....
  8. doi request reprint Quantification of tonic and phasic muscle activity in REM sleep behavior disorder
    Geert Mayer
    Department of Neurology, Hephata Klinik, Schwalmstadt Treysa, Germany
    J Clin Neurophysiol 25:48-55. 2008
    ....
  9. ncbi request reprint Sleep related rhythmic movement disorder revisited
    Geert Mayer
    Hephata Klinik, Department of Neurology, Schwalmstadt, Germany
    J Sleep Res 16:110-6. 2007
    ..In the adult patients it is not associated with mental pathologies and can be triggered by sleep apnea...
  10. ncbi request reprint [The neurophysiology of cataplexy]
    G Mayer
    Hephata Klinik, Schwalmstadt Treysa
    Nervenarzt 76:1464, 1466-9. 2005
    ..An understanding of the neuronal mechanisms responsible for cataplexies is essential for the development of new anticataplectic medications...
  11. ncbi request reprint [Effect of the new drug provisions on the drug treatment of narcolepsy]
    G Mayer
    Hephata Klinik, Schwalmstadt Treysa
    Dtsch Med Wochenschr 129:1198-201. 2004
  12. ncbi request reprint Ritanserin improves sleep quality in narcolepsy
    G Mayer
    Hephata Klinik, Schwalmstadt Treysa, Germany
    Pharmacopsychiatry 36:150-5. 2003
    ..In conclusion, ritanserin may serve as add-on medication for the treatment of impaired sleep quality in narcoleptic patients, but not as a stimulant or hypnotic type of medication...
  13. ncbi request reprint Health-related quality of life in patients with narcolepsy
    Richard Dodel
    Department of Neurology, Philipps University, Marburg, Germany
    Sleep Med 8:733-41. 2007
    ..To evaluate the health-related quality of life (HRQoL) in patients suffering from narcolepsy...
  14. doi request reprint Patients with idiopathic rapid-eye-movement sleep behavior disorder show normal gastric motility assessed by the 13C-octanoate breath test
    Marcus M Unger
    Department of Neurology, Philipps University Marburg, Marburg, Germany
    Mov Disord 26:2559-63. 2011
    ..Few data exist on gastric emptying in early-stage Parkinson's disease. In idiopathic rapid-eye-movement sleep behavior disorder, a presumable pre-motor stage of Parkinson's disease, gastric emptying has not yet been investigated...
  15. doi request reprint Unimpaired postprandial pancreatic polypeptide secretion in Parkinson's disease and REM sleep behavior disorder
    Marcus M Unger
    Department of Neurology, Philipps University Marburg, Marburg, Germany
    Mov Disord 28:529-33. 2013
    ..The release is operated by vagal-abdominal projections and has therefore been suggested as a test for vagal nerve integrity. Pathoanatomical and clinical studies indicate vagal dysfunction in early Parkinson's disease (PD)...
  16. doi request reprint Postprandial ghrelin response is reduced in patients with Parkinson's disease and idiopathic REM sleep behaviour disorder: a peripheral biomarker for early Parkinson's disease?
    Marcus M Unger
    Department of Neurology, Philipps Universitat Marburg, Rudolf Bultmann Strasse 8, 35033, Marburg, Germany
    J Neurol 258:982-90. 2011
    ..The impaired ghrelin excretion might qualify as a peripheral biomarker and be of diagnostic or therapeutic value...
  17. doi request reprint Elevated glial fibrillary acidic protein levels in the cerebrospinal fluid of patients with narcolepsy
    Emily Feneberg
    Department of Neurology, University of Ulm, Germany
    Sleep Med 14:692-4. 2013
    ..In conclusion, GFAP may be useful as an additional disease biomarker in patients with narcolepsy, and this hypothesis should be investigated in larger studies. ..
  18. pmc Diffusion tensor imaging in idiopathic REM sleep behavior disorder reveals microstructural changes in the brainstem, substantia nigra, olfactory region, and other brain regions
    Marcus M Unger
    Department of Neurology, Philipps Universitat Marburg, Marburg, Germany
    Sleep 33:767-73. 2010
    ....
  19. doi request reprint Transcranial midbrain sonography in narcoleptic subjects with and without concomitant REM sleep behaviour disorder
    Marcus M Unger
    Department of Neurology, Philipps Universitat Marburg, Rudolf Bultmann Str 8, 35039, Marburg, Germany
    J Neurol 256:874-7. 2009
    ..Reduced echogenicity of the brainstem raphe might indicate an involvement of the serotonergic system in narcoleptic subjects with RBD...
  20. doi request reprint Health economic burden of patients with restless legs syndrome in a German ambulatory setting
    Richard Dodel
    Department of Neurology, Philipps University Marburg, Marburg, Germany
    Pharmacoeconomics 28:381-93. 2010
    ..RLS places a notable financial burden on society as well as on patients and their families. More detailed studies are needed to evaluate the health economic impact of this disorder...
  21. doi request reprint Assessment of idiopathic rapid-eye-movement sleep behavior disorder by transcranial sonography, olfactory function test, and FP-CIT-SPECT
    Marcus M Unger
    Department of Neurology, Philipps Universitat Marburg, Germany
    Mov Disord 23:596-9. 2008
    ..Large-size longitudinal studies in iRBD patients are required to evaluate the usefulness of diagnostic tests to identify the subgroup of iRBD patients that is prone to develop PD...
  22. ncbi request reprint The REM sleep behavior disorder screening questionnaire--a new diagnostic instrument
    Karin Stiasny-Kolster
    Department of Neurology, Center of Nervous Diseases, Philipps University, Marburg, Germany
    Mov Disord 22:2386-93. 2007
    ..02 +/- 1.78) was significantly lower than in the RBD group (P < 0.0005), revealing a specificity of 0.92. Due to its high sensitivity, the RBDSQ appears to be particularly useful as a screening tool...
  23. ncbi request reprint [Comorbidity in narcoleptic patients]
    G Mayer
    Hephata Klinik, Schwalmstadt Treysa
    Dtsch Med Wochenschr 127:1942-6. 2002
    ..Narcolepsy is a rare disease which remains undiagnosed in 90 %. The international literature so far has paid little attention to comorbid disorders...
  24. ncbi request reprint [Differential diagnosis of seizures in sleep]
    G Mayer
    Hephata Klinik, Schwalmstadt-Treysa
    Pneumologie 51:698-705. 1997
    ..EEG recordings with at least 16 channels and EMGs from several muscles are necessary for differential diagnosis. Video-documentation often reveals relevant additional information confirming the diagnosis...
  25. doi request reprint From bench to bed: putative animal models of REM sleep behavior disorder (RBD)
    Martina Krenzer
    Department of Neurology, Philipps Universitat Marburg, Marburg, Germany
    J Neural Transm 120:683-8. 2013
    ..In order to elucidate these questions, a constant interaction between basic and clinical researchers is required, which might, ultimately, create an early therapeutic window for neurodegenerative disorders...
  26. ncbi request reprint The socioeconomic impact of narcolepsy
    Richard Dodel
    Department of Neurology, Friedrich Wilhelms University Bonn, Germany
    Sleep 27:1123-8. 2004
    ..To evaluate the economic burden of patients suffering from narcolepsy...
  27. ncbi request reprint Combination of 'idiopathic' REM sleep behaviour disorder and olfactory dysfunction as possible indicator for alpha-synucleinopathy demonstrated by dopamine transporter FP-CIT-SPECT
    K Stiasny-Kolster
    Department of Neurology, Center of Nervous Diseases, Philipps University of Marburg, Germany
    Brain 128:126-37. 2005
    ..Since narcoleptic patients are not known to have an increased risk of developing parkinsonism, the pathophysiology and clinical relevance of hyposmia in RBD/narcolepsy patients requires further research...
  28. doi request reprint One year open-label safety and efficacy trial with rotigotine transdermal patch in moderate to severe idiopathic restless legs syndrome
    Wolfgang H Oertel
    Department of Neurology, Philipps Universitat, Marburg, Germany
    Sleep Med 9:865-73. 2008
    ..Long-term efficacy and tolerability data are not yet available for patch formulations of dopamine agonists in restless legs syndrome...
  29. ncbi request reprint Efficacy of rotigotine transdermal system in severe restless legs syndrome: a randomized, double-blind, placebo-controlled, six-week dose-finding trial in Europe
    Wolfgang H Oertel
    Department of Neurology, Philipps University, Rudolf Bultmann Strasse 8, D 35039 Marburg, Germany
    Sleep Med 9:228-39. 2008
    ..In a pilot placebo-controlled study, low dosages of 0.5-2mg/24h rotigotine showed a dose-dependent beneficial effect in restless legs syndrome (RLS) patients...
  30. ncbi request reprint Olfactory dysfunction in patients with narcolepsy with and without REM sleep behaviour disorder
    K Stiasny-Kolster
    Department of Neurology, Center of Nervous Diseases, Philipps University of Marburg, Schwalmstadt Treysa, Germany
    Brain 130:442-9. 2007
    ..In contrast to patients with idiopathic RBD, hyposmia in patients with RBD associated with narcolepsy is unlikely to be a predictor for developing parkinsonism...
  31. ncbi request reprint Attention deficits in patients with narcolepsy
    Martina Rieger
    Max Planck Institute for Psychological Research, Munich
    Sleep 26:36-43. 2003
    ..Therefore, we conducted a systematic investigation of different aspects of attention and verbal memory in patients with narcolepsy...