Jan P Schouten

Summary

Publications

  1. pmc Relative quantification of 40 nucleic acid sequences by multiplex ligation-dependent probe amplification
    Jan P Schouten
    MRC Holland, Hudsonstraat 68, 1057SN Amsterdam, The Netherlands
    Nucleic Acids Res 30:e57. 2002
  2. ncbi request reprint Deletion and duplication screening in the DMD gene using MLPA
    Tanja Lalic
    Department of Medical Genetics, Mother and Child Health Institute of Serbia, Radoja Dakic, Belgrade, Serbia and Montenegro
    Eur J Hum Genet 13:1231-4. 2005
  3. pmc A novel approach to simultaneously scan genes at fragile sites
    Pascale Willem
    Department of Hematology and Molecular Medicine University of the Witwatersrand and the National Health Laboratory Services, Wits Medical School, 8 York road, 2193 Parktown, South Africa
    BMC Cancer 6:205. 2006
  4. ncbi request reprint Large genomic deletions and duplications in the BRCA1 gene identified by a novel quantitative method
    Frans B L Hogervorst
    Family Cancer Clinic, Netherlands Cancer Institute, Amsterdam, The Netherlands
    Cancer Res 63:1449-53. 2003
  5. ncbi request reprint Delineating genetic pathways of disease progression in head and neck squamous cell carcinoma
    Maria J Worsham
    Department of Otolaryngology Head and Neck Surgery, Research Division, Henry Ford Health System, Detroit, MI 48202, USA
    Arch Otolaryngol Head Neck Surg 129:702-8. 2003
  6. ncbi request reprint Epigenetic events of disease progression in head and neck squamous cell carcinoma
    Maria J Worsham
    Department of Otolaryngology Head and Neck Surgery and Research Division, Henry Ford Health System, Detroit, Mich, USA
    Arch Otolaryngol Head Neck Surg 132:668-77. 2006
  7. pmc Rapid and quantitative detection of homologous and non-homologous recombination events using three oligonucleotide MLPA
    Petra Langerak
    Division of Immunology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
    Nucleic Acids Res 33:e188. 2005
  8. pmc Methylation-specific MLPA (MS-MLPA): simultaneous detection of CpG methylation and copy number changes of up to 40 sequences
    Anders O H Nygren
    MRC Holland bv Amsterdam, The Netherlands
    Nucleic Acids Res 33:e128. 2005
  9. ncbi request reprint A disintegrin and metalloprotease 33 polymorphisms and lung function decline in the general population
    Cleo C van Diemen
    Department of Epidemiology and Bioinformatics, University of Groningen, The Netherlands
    Am J Respir Crit Care Med 172:329-33. 2005
  10. doi request reprint Pharmacogenomics and outcome of asthma: no clinical application for long-term steroid effects by CRHR1 polymorphisms
    Antoon Dijkstra
    J Allergy Clin Immunol 121:1510-3. 2008

Collaborators

  • Fred H Menko
  • S J White
  • Maria Worsham
  • Anders O H Nygren
  • Antoon Dijkstra
  • Marcel Bruinenberg
  • Judith M Vonk
  • Dirkje S Postma
  • Pascale Willem
  • Tanja Lalic
  • Petra Langerak
  • Cleo C van Diemen
  • Frans B L Hogervorst
  • Gerard H Koppelman
  • Jacqueline Brown
  • Heinz Jacobs
  • Johan T den Dunnen
  • Marina Djurisic
  • Quinten Waisfisz
  • Abdellatif Errami
  • Helena M B Duarte
  • Raymon N C P Vijzelaar
  • Rolf H A M Vossen
  • Najim Ameziane
  • Jordy Coffa
  • Corine J Hess
  • Danijela Radivojevic
  • H Marike Boezen
  • Marija Guc-Scekic
  • Martyn H Breuning
  • Cathal J McElgunn
  • Johan J P Gille
  • Roelof Pruntel
  • Charlotte Dommering
  • Senno Verhoef
  • Rein Regnerus
  • Maartje Grippeling
  • Irma Kluijt
  • Laura J Van't Veer
  • Petra M Nederlof
  • Resie van Spaendonk
  • Tibor van Welsem
  • Gerard Pals

Detail Information

Publications10

  1. pmc Relative quantification of 40 nucleic acid sequences by multiplex ligation-dependent probe amplification
    Jan P Schouten
    MRC Holland, Hudsonstraat 68, 1057SN Amsterdam, The Netherlands
    Nucleic Acids Res 30:e57. 2002
    ..Probe target sequences are small (50-70 nt). The prerequisite of a ligation reaction provides the opportunity to discriminate single nucleotide differences...
  2. ncbi request reprint Deletion and duplication screening in the DMD gene using MLPA
    Tanja Lalic
    Department of Medical Genetics, Mother and Child Health Institute of Serbia, Radoja Dakic, Belgrade, Serbia and Montenegro
    Eur J Hum Genet 13:1231-4. 2005
    ..The assay outperforms the Beggs and Chamberlain multiplex-PCR test, and should be considered as the method of choice for an initial DNA analysis of DMD/BMD patients...
  3. pmc A novel approach to simultaneously scan genes at fragile sites
    Pascale Willem
    Department of Hematology and Molecular Medicine University of the Witwatersrand and the National Health Laboratory Services, Wits Medical School, 8 York road, 2193 Parktown, South Africa
    BMC Cancer 6:205. 2006
    ..The loci for FHIT and WWOX both span over a megabase but the genes encode for small transcripts. Thus the screening of intragenic deletion can be difficult and has relied on loss of heterozygosity LOH assays, or genomic arrays...
  4. ncbi request reprint Large genomic deletions and duplications in the BRCA1 gene identified by a novel quantitative method
    Frans B L Hogervorst
    Family Cancer Clinic, Netherlands Cancer Institute, Amsterdam, The Netherlands
    Cancer Res 63:1449-53. 2003
    ..The MLPA test for BRCA1 ensures a sensitive and comprehensive high-throughput screening test for genomic rearrangement and can easily be implemented in the molecular analysis of BRCA1...
  5. ncbi request reprint Delineating genetic pathways of disease progression in head and neck squamous cell carcinoma
    Maria J Worsham
    Department of Otolaryngology Head and Neck Surgery, Research Division, Henry Ford Health System, Detroit, MI 48202, USA
    Arch Otolaryngol Head Neck Surg 129:702-8. 2003
    ..Identification of key molecular events may be useful for more accurate distinction of prognostic groups for selection and targeting of therapy...
  6. ncbi request reprint Epigenetic events of disease progression in head and neck squamous cell carcinoma
    Maria J Worsham
    Department of Otolaryngology Head and Neck Surgery and Research Division, Henry Ford Health System, Detroit, Mich, USA
    Arch Otolaryngol Head Neck Surg 132:668-77. 2006
    ..To examine the promoter methylation status of the 22 cancer genes and their contribution to disease progression in 6 head and neck squamous cell carcinoma (HNSCC) cell lines...
  7. pmc Rapid and quantitative detection of homologous and non-homologous recombination events using three oligonucleotide MLPA
    Petra Langerak
    Division of Immunology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
    Nucleic Acids Res 33:e188. 2005
    ..By using MLPA probes consisting of three oligonucleotides we were able to simultaneously detect and quantify both wild-type and mutant alleles...
  8. pmc Methylation-specific MLPA (MS-MLPA): simultaneous detection of CpG methylation and copy number changes of up to 40 sequences
    Anders O H Nygren
    MRC Holland bv Amsterdam, The Netherlands
    Nucleic Acids Res 33:e128. 2005
    ..To validate this novel method, we used MS-MLPA to detect aberrant methylation in DNA samples of patients with Prader-Willy syndrome, Angelman syndrome or acute myeloid leukemia...
  9. ncbi request reprint A disintegrin and metalloprotease 33 polymorphisms and lung function decline in the general population
    Cleo C van Diemen
    Department of Epidemiology and Bioinformatics, University of Groningen, The Netherlands
    Am J Respir Crit Care Med 172:329-33. 2005
    ....
  10. doi request reprint Pharmacogenomics and outcome of asthma: no clinical application for long-term steroid effects by CRHR1 polymorphisms
    Antoon Dijkstra
    J Allergy Clin Immunol 121:1510-3. 2008