Axel Schlitt

Summary

Publications

  1. ncbi request reprint Herpesvirus DNA (Epstein-Barr virus, herpes simplex virus, cytomegalovirus) in circulating monocytes of patients with coronary artery disease
    Axel Schlitt
    Department of Medicine II and Virology, and Institute for Clinical Chemistry and Laboratory Medicine, Johannes Gutenberg University, Germany
    Acta Cardiol 60:605-10. 2005
  2. ncbi request reprint Prognostic value of lipoproteins and their relation to inflammatory markers among patients with coronary artery disease
    Axel Schlitt
    Department of Medicine II, Institute of Clinical Chemistry and Laboratory Medicine, Johannes Gutenberg University, 55101 Mainz, Germany
    Int J Cardiol 102:477-85. 2005
  3. ncbi request reprint Anti-inflammatory effects of phospholipid transfer protein (PLTP) deficiency in mice
    Axel Schlitt
    Department of Anatomy and Cell Biology, State University of New York, Downstate Medical Center, Brooklyn, 11203, USA
    Biochim Biophys Acta 1733:187-91. 2005
  4. ncbi request reprint Serum sphingomyelin levels are related to the clearance of postprandial remnant-like particles
    Axel Schlitt
    Department of Anatomy and Cell Biology and Scientific Computing Center, State University of New York, Downstate Medical Center, Brooklyn, NY, USA
    J Lipid Res 46:196-200. 2005
  5. ncbi request reprint CD14+CD16+ monocytes in coronary artery disease and their relationship to serum TNF-alpha levels
    Axel Schlitt
    Department of Medicine II and Institute of Clinical Chemistry and Laboratory Medicine, Johannes Gutenberg University, Mainz, Germany
    Thromb Haemost 92:419-24. 2004
  6. ncbi request reprint Fondaparinux and enoxaparin in comparison to unfractionated heparin in preventing thrombus formation on mechanical heart valves in an ex vivo rabbit model
    Axel Schlitt
    Department of Medicine II, Johannes Gutenberg University, 55101 Mainz, Germany
    Thromb Haemost 90:245-51. 2003
  7. ncbi request reprint Clopidogrel and aspirin in the prevention of thromboembolic complications after mechanical aortic valve replacement (CAPTA)
    Axel Schlitt
    Department of Medicine II, Johannes Gutenberg University Mainz, Langenbeckstr 1, 55131 Mainz, Germany
    Thromb Res 109:131-5. 2003
  8. ncbi request reprint High plasma phospholipid transfer protein levels as a risk factor for coronary artery disease
    Axel Schlitt
    Department of Medicine II, Johannes Gutenberg University, Mainz, Germany
    Arterioscler Thromb Vasc Biol 23:1857-62. 2003
  9. ncbi request reprint Comparison of fondaparinux, low molecular-weight heparin and unfractionated heparin in preventing thrombus formation on mechanical heart valves: results of an in-vitro study
    Axel Schlitt
    Department of Medicine II, Department of Cardiovascular Surgery, and Transfusion Center, Johannes Gutenberg University, Mainz, Germany
    J Heart Valve Dis 15:809-14. 2006
  10. ncbi request reprint Monocyte-derived dendritic cells of patients with coronary artery disease show an increased expression of costimulatory molecules CD40, CD80 and CD86 in vitro
    Jörn F Dopheide
    Department of Medicine II, Johannes Gutenberg University, Mainz, Germany
    Coron Artery Dis 18:523-31. 2007

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Herpesvirus DNA (Epstein-Barr virus, herpes simplex virus, cytomegalovirus) in circulating monocytes of patients with coronary artery disease
    Axel Schlitt
    Department of Medicine II and Virology, and Institute for Clinical Chemistry and Laboratory Medicine, Johannes Gutenberg University, Germany
    Acta Cardiol 60:605-10. 2005
    ..As a possible trigger, several studies in recent years have suggested that different viruses and bacteria are associated with atherosclerotic diseases...
  2. ncbi request reprint Prognostic value of lipoproteins and their relation to inflammatory markers among patients with coronary artery disease
    Axel Schlitt
    Department of Medicine II, Institute of Clinical Chemistry and Laboratory Medicine, Johannes Gutenberg University, 55101 Mainz, Germany
    Int J Cardiol 102:477-85. 2005
    ..There is growing evidence indicating that those lipoprotein factors are related to the inflammatory process in atherogenesis...
  3. ncbi request reprint Anti-inflammatory effects of phospholipid transfer protein (PLTP) deficiency in mice
    Axel Schlitt
    Department of Anatomy and Cell Biology, State University of New York, Downstate Medical Center, Brooklyn, 11203, USA
    Biochim Biophys Acta 1733:187-91. 2005
    ..The results of our experiments demonstrated an anti-inflammatory effect of PLTP deficiency as a further aspect of its proatherogenic potency...
  4. ncbi request reprint Serum sphingomyelin levels are related to the clearance of postprandial remnant-like particles
    Axel Schlitt
    Department of Anatomy and Cell Biology and Scientific Computing Center, State University of New York, Downstate Medical Center, Brooklyn, NY, USA
    J Lipid Res 46:196-200. 2005
    ..Serum SM was positively correlated with serum TG (P <0.001), RLP SM (P <0.001), RLP TG (P <0.001), and RLP cholesterol (P <0.001) levels. It is our conclusion that serum SM is a marker for the clearance of RLPs...
  5. ncbi request reprint CD14+CD16+ monocytes in coronary artery disease and their relationship to serum TNF-alpha levels
    Axel Schlitt
    Department of Medicine II and Institute of Clinical Chemistry and Laboratory Medicine, Johannes Gutenberg University, Mainz, Germany
    Thromb Haemost 92:419-24. 2004
    ..In accordance, recent animal studies suggest a possibly important role of these monocytes in the development of atherosclerosis...
  6. ncbi request reprint Fondaparinux and enoxaparin in comparison to unfractionated heparin in preventing thrombus formation on mechanical heart valves in an ex vivo rabbit model
    Axel Schlitt
    Department of Medicine II, Johannes Gutenberg University, 55101 Mainz, Germany
    Thromb Haemost 90:245-51. 2003
    ....
  7. ncbi request reprint Clopidogrel and aspirin in the prevention of thromboembolic complications after mechanical aortic valve replacement (CAPTA)
    Axel Schlitt
    Department of Medicine II, Johannes Gutenberg University Mainz, Langenbeckstr 1, 55131 Mainz, Germany
    Thromb Res 109:131-5. 2003
  8. ncbi request reprint High plasma phospholipid transfer protein levels as a risk factor for coronary artery disease
    Axel Schlitt
    Department of Medicine II, Johannes Gutenberg University, Mainz, Germany
    Arterioscler Thromb Vasc Biol 23:1857-62. 2003
    ..PLTP-deficient mice have demonstrated increased antioxidation potential as well as a decrease in apolipoprotein B secretion and atherosclerotic lesions. In humans, high PLTP is associated with type II diabetes and obesity...
  9. ncbi request reprint Comparison of fondaparinux, low molecular-weight heparin and unfractionated heparin in preventing thrombus formation on mechanical heart valves: results of an in-vitro study
    Axel Schlitt
    Department of Medicine II, Department of Cardiovascular Surgery, and Transfusion Center, Johannes Gutenberg University, Mainz, Germany
    J Heart Valve Dis 15:809-14. 2006
    ..The study aim was to investigate the efficacy of three different anticoagulants in preventing thrombus formation on mechanical heart valves, using an in-vitro system...
  10. ncbi request reprint Monocyte-derived dendritic cells of patients with coronary artery disease show an increased expression of costimulatory molecules CD40, CD80 and CD86 in vitro
    Jörn F Dopheide
    Department of Medicine II, Johannes Gutenberg University, Mainz, Germany
    Coron Artery Dis 18:523-31. 2007
    ..So far, their role in atherosclerosis has not been fully elucidated. We investigated the phenotypic properties of DCs in patients with coronary artery disease (CAD) in comparison to healthy individuals...
  11. ncbi request reprint Relation of markers of inflammation (C-reactive protein, fibrinogen, von Willebrand factor, and leukocyte count) and statin therapy to long-term mortality in patients with angiographically proven coronary artery disease
    Christoph Bickel
    Department of Medicine II, Johannes Gutenberg University Mainz, Germany
    Am J Cardiol 89:901-8. 2002
    ..Statin therapy is associated with elevated hs-CRP, with a risk reduction for fatal coronary events, independent of LDL levels; this, in part, may be explained by the anti-inflammatory effects on atherosclerosis...
  12. ncbi request reprint Phospholipid transfer protein in hemodialysis patients
    Axel Schlitt
    Department of Medicine III, Martin Luther University, Halle Wittenberg, Germany
    Am J Nephrol 27:138-43. 2007
    ..The role of PLTP in atherogenesis is still controversial. We aimed to investigate PLTP activity in hemodialysis (HD) patients, a population which has an increased risk for the development of atherosclerosis...
  13. doi request reprint In-vitro comparison of fondaparinux, unfractionated heparin, and enoxaparin in preventing cardiac catheter-associated thrombus
    Axel Schlitt
    Department of Medicine III, Martin Luther University Halle Wittenberg, Halle Wittenberg, Germany
    Coron Artery Dis 19:279-84. 2008
    ..Unexpectedly, there was an increase in catheter-related thrombus formation during percutaneous coronary interventions in fonda-treated patients...
  14. ncbi request reprint Myocardial ischemia/reperfusion causes VDAC phosphorylation which is reduced by cardioprotection with a p38 MAP kinase inhibitor
    Hansjorg Schwertz
    Department of Internal Medicine III, Martin Luther University, Halle Wittenberg, Halle Saale, Germany
    Proteomics 7:4579-88. 2007
    ..Thus, p38 MAP kinase inhibition with PD169316 is cardioprotective, reduces neutrophil activation, and controls protein expression and phosphorylation in MI and reperfusion...
  15. ncbi request reprint Apoptosis contributes to septic cardiomyopathy and is improved by simvastatin therapy
    Ute Buerke
    Department of Medicine III, Martin Luther University, Halle Saale, Germany
    Shock 29:497-503. 2008
    ..We provide novel evidence for the mechanisms by which septicemia causes myocardial depression and hint at a potential role for simvastatin as an inhibitor of apoptosis in sepsis...
  16. doi request reprint Serine protease inhibitor nafamostat given before reperfusion reduces inflammatory myocardial injury by complement and neutrophil inhibition
    Hansjorg Schwertz
    Department of Medicine III, Martin Luther University, Halle, Germany
    J Cardiovasc Pharmacol 52:151-60. 2008
    ..Reduced leukocyte accumulation and complement activity seem involved in the mechanism of this cardioprotective effect...