Luregn J Schlapbach

Summary

Publications

  1. ncbi request reprint Impact of sepsis on neurodevelopmental outcome in a Swiss National Cohort of extremely premature infants
    Luregn J Schlapbach
    NICU and PICU, Department of Pediatrics, Inselspital, University of Bern, 3010 Bern, Switzerland
    Pediatrics 128:e348-57. 2011
  2. pmc Copeptin concentration in cord blood in infants with early-onset sepsis, chorioamnionitis and perinatal asphyxia
    Luregn J Schlapbach
    Neonatal and Pediatric Intensive Care Unit, Department of Pediatrics, University of Bern, Switzerland
    BMC Pediatr 11:38. 2011
  3. ncbi request reprint Higher cord blood levels of mannose-binding lectin-associated serine protease-2 in infants with necrotising enterocolitis
    Luregn J Schlapbach
    Department of Pediatrics, University of Bern, 3010 Bern, Switzerland
    Pediatr Res 64:562-6. 2008
  4. pmc Outcome at two years of age in a Swiss national cohort of extremely preterm infants born between 2000 and 2008
    Luregn J Schlapbach
    Neonatal and Paediatric Intensive Care Unit, Department of Paediatrics, University of Bern, Bern, Switzerland
    BMC Pediatr 12:198. 2012
  5. ncbi request reprint M-ficolin in children with cancer
    Luregn J Schlapbach
    Department of Pediatrics, Inselspital, University of Bern, CH 3010 Bern, Switzerland
    Immunobiology 216:633-8. 2011
  6. ncbi request reprint Serum concentrations of lectin-pathway components in healthy neonates, children and adults: mannan-binding lectin (MBL), M-, L-, and H-ficolin, and MBL-associated serine protease-2 (MASP-2)
    Seraina Sallenbach
    Department of Pediatrics, University of Bern, Bern, Switzerland
    Pediatr Allergy Immunol 22:424-30. 2011
  7. ncbi request reprint Differential role of the lectin pathway of complement activation in susceptibility to neonatal sepsis
    Luregn J Schlapbach
    Departments of Pediatrics, University of Bern, Bern, Switzerland
    Clin Infect Dis 51:153-62. 2010
  8. ncbi request reprint Good agreement between capillary and venous sampling for lectin pathway proteins
    Luregn J Schlapbach
    Neonatal and Pediatric Intensive Care Unit, Department of Pediatrics, University of Berne, Berne, Switzerland
    Immunobiology 218:465-9. 2013
  9. ncbi request reprint Mannan-binding lectin (MBL) and MBL-associated serine protease-2 in children with cancer
    Urs P Fisch
    Department of Pediatrics, University of Bern, Switzerland
    Swiss Med Wkly 141:w13191. 2011
  10. ncbi request reprint Impact of chorioamnionitis and preeclampsia on neurodevelopmental outcome in preterm infants below 32 weeks gestational age
    Luregn J Schlapbach
    Department of Pediatrics, University of Bern, Switzerland
    Acta Paediatr 99:1504-9. 2010

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Impact of sepsis on neurodevelopmental outcome in a Swiss National Cohort of extremely premature infants
    Luregn J Schlapbach
    NICU and PICU, Department of Pediatrics, Inselspital, University of Bern, 3010 Bern, Switzerland
    Pediatrics 128:e348-57. 2011
    ..This study aimed to determine the impact of sepsis on neurodevelopment at 2 years' corrected age in extremely preterm infants...
  2. pmc Copeptin concentration in cord blood in infants with early-onset sepsis, chorioamnionitis and perinatal asphyxia
    Luregn J Schlapbach
    Neonatal and Pediatric Intensive Care Unit, Department of Pediatrics, University of Bern, Switzerland
    BMC Pediatr 11:38. 2011
    ..In contrast, its involvement in neonatal diseases remains unknown. The aim of this study was to establish copeptin concentrations in neonates of different stress states such as sepsis, chorioamnionitis and asphyxia...
  3. ncbi request reprint Higher cord blood levels of mannose-binding lectin-associated serine protease-2 in infants with necrotising enterocolitis
    Luregn J Schlapbach
    Department of Pediatrics, University of Bern, 3010 Bern, Switzerland
    Pediatr Res 64:562-6. 2008
    ..64). In conclusion, infants later developing NEC had significantly higher MASP-2 cord blood levels compared with controls. Higher MASP-2 may favor complement-mediated inflammation and could thereby predispose to NEC...
  4. pmc Outcome at two years of age in a Swiss national cohort of extremely preterm infants born between 2000 and 2008
    Luregn J Schlapbach
    Neonatal and Paediatric Intensive Care Unit, Department of Paediatrics, University of Bern, Bern, Switzerland
    BMC Pediatr 12:198. 2012
    ..Representative current data on the severity of disability and of risk factors associated with poor outcome in this growing population are necessary for clinical guidance and parent counselling...
  5. ncbi request reprint M-ficolin in children with cancer
    Luregn J Schlapbach
    Department of Pediatrics, Inselspital, University of Bern, CH 3010 Bern, Switzerland
    Immunobiology 216:633-8. 2011
    ..The aim of this study was to explore association of M-ficolin with clinical and hematological parameters, and to investigate whether the risk of chemotherapy-related infections was related to M-ficolin concentrations in serum...
  6. ncbi request reprint Serum concentrations of lectin-pathway components in healthy neonates, children and adults: mannan-binding lectin (MBL), M-, L-, and H-ficolin, and MBL-associated serine protease-2 (MASP-2)
    Seraina Sallenbach
    Department of Pediatrics, University of Bern, Bern, Switzerland
    Pediatr Allergy Immunol 22:424-30. 2011
    ..The respective normal ranges for adults should not be used in the pediatric population. The age-specific pediatric ranges established here may be used instead...
  7. ncbi request reprint Differential role of the lectin pathway of complement activation in susceptibility to neonatal sepsis
    Luregn J Schlapbach
    Departments of Pediatrics, University of Bern, Bern, Switzerland
    Clin Infect Dis 51:153-62. 2010
    ..The decreased expression of lectin pathway proteins in neonates must be considered to be an additional form of neonatal immunodeficiency...
  8. ncbi request reprint Good agreement between capillary and venous sampling for lectin pathway proteins
    Luregn J Schlapbach
    Neonatal and Pediatric Intensive Care Unit, Department of Pediatrics, University of Berne, Berne, Switzerland
    Immunobiology 218:465-9. 2013
    ..So far, studies were exclusively based on venous samples. The aim of this study was to investigate whether measurements of lectin pathway proteins obtained by capillary sampling are in agreement with venous samples...
  9. ncbi request reprint Mannan-binding lectin (MBL) and MBL-associated serine protease-2 in children with cancer
    Urs P Fisch
    Department of Pediatrics, University of Bern, Switzerland
    Swiss Med Wkly 141:w13191. 2011
    ..This study aimed to determine if serum concentrations of MBL and MASP-2 differ between children with cancer and healthy age-matched controls...
  10. ncbi request reprint Impact of chorioamnionitis and preeclampsia on neurodevelopmental outcome in preterm infants below 32 weeks gestational age
    Luregn J Schlapbach
    Department of Pediatrics, University of Bern, Switzerland
    Acta Paediatr 99:1504-9. 2010
    ..Intrauterine conditions may interfere with foetal brain development. We compared the neurodevelopmental outcome between infants <32 weeks gestational age after maternal preeclampsia or chorioamnionitis and controls...
  11. ncbi request reprint Pancreatic stone protein as a novel marker for neonatal sepsis
    Luregn J Schlapbach
    Neonatal and Pediatric Intensive Care Unit, Department of Paediatrics, University of Berne, Bern, Switzerland
    Intensive Care Med 39:754-63. 2013
    ..Pancreatic stone protein (PSP) is a promising sepsis marker in adults. The aim of this study was to investigate whether determining PSP improves the diagnosis of EOS in comparison with other infection markers...
  12. ncbi request reprint M-ficolin in the neonatal period: Associations with need for mechanical ventilation and mortality in premature infants with necrotising enterocolitis
    Luregn J Schlapbach
    Department of Pediatrics, Inselspital, University of Bern, Switzerland
    Mol Immunol 46:2597-603. 2009
    ..M-, L- and H-ficolins recognize microorganisms and activate the complement system, but their role in host defense is largely unknown. This study investigated whether ficolin concentrations are associated with NEC...
  13. ncbi request reprint Prognosis in pediatric hematologic malignancies is associated with serum concentration of mannose-binding lectin-associated serine protease-2 (MASP-2)
    Aina Zehnder
    Department of Pediatrics, University of Bern, Bern, Switzerland
    Pediatr Blood Cancer 53:53-7. 2009
    ..Their serum concentrations show a wide interindividual variability. This study investigated whether the concentration of MBL and MASP-2 is associated with prognosis in pediatric patients with cancer...