The significance of at-risk symptoms for psychosis in children and adolescentsBenno Graf Schimmelmann
University Hospital of Child and Adolescent Psychiatry, University of Bern, Bern, Switzerland
Can J Psychiatry 58:32-40. 2013
..A preliminary rationale for how to deal with at-risk symptoms for psychosis in clinical practice is provided...
Prevalence and impact of cannabis use disorders in adolescents with early onset first episode psychosisB G Schimmelmann
University Hospital of Child and Adolescent Psychiatry, Bolligenstr 111, 3000 Bern 60, Switzerland
Eur Psychiatry 27:463-9. 2012
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Cannabis use disorder and age at onset of psychosis--a study in first-episode patientsBenno G Schimmelmann
University Hospital of Child and Adolescent Psychiatry, Bern, Switzerland
Schizophr Res 129:52-6. 2011
..Previous studies included CUD co-morbid with other substance use disorders (SUD), and many did not control for confounders...
Exploring the genetic link between RLS and ADHDB G Schimmelmann
Department of Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg Essen, LVR Klinikun Essen, Virchowstr 174, 45147 Essen, Germany
J Psychiatr Res 43:941-5. 2009
..Genes relevant to RLS remain interesting candidates for ADHD; particularly BTBD9 needs further study, as it has been related to iron storage, a potential pathophysiological link between RLS and certain subtypes of ADHD...
A prospective 12-week study of quetiapine in adolescents with schizophrenia spectrum disordersBenno Graf Schimmelmann
Department of Child and Adolescent Psychiatry, University of Duisburg Essen, Virchowstrasse 174, 45147 Essen, Germany
J Child Adolesc Psychopharmacol 17:768-78. 2007
..The aim of this study was to investigate the effectiveness, tolerability, and safety of quetiapine in adolescents with schizophrenia, schizophreniform, and schizoaffective disorders in a prospective open-label study...
Impact of duration of untreated psychosis on pre-treatment, baseline, and outcome characteristics in an epidemiological first-episode psychosis cohortBenno G Schimmelmann
Department of Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg Essen, Virchowstrasse 174, 45147 Essen, Germany
J Psychiatr Res 42:982-90. 2008
..To assess the impact of duration of untreated psychosis (DUP) on baseline and 18-month follow-up characteristics controlling for relevant confounders in an epidemiological first-episode psychosis (FEP) cohort...
Pre-treatment, baseline, and outcome differences between early-onset and adult-onset psychosis in an epidemiological cohort of 636 first-episode patientsBenno G Schimmelmann
Department of Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg Essen, Virchowstr 174, 45147 Essen, Germany
Schizophr Res 95:1-8. 2007
..To assess pre-treatment, baseline, and outcome differences of patients with early- (onset<age 18) and adult-onset (onset>or=age 18) psychosis in an epidemiological cohort of first-episode patients...
Subjective distress related to side effects and subjective well-being in first admitted adolescents with early-onset psychosis treated with atypical antipsychoticsBenno Graf Schimmelmann
Department of Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg Essen, Essen, Germany
J Child Adolesc Psychopharmacol 15:249-58. 2005
..The aim of this pilot study was to evaluate the subjective distress-related to different SE and its association with subjective well-being in a sample of adolescents treated with atypical antipsychotics...
Diagnostic stability 18 months after treatment initiation for first-episode psychosisBenno G Schimmelmann
Centre for Psychosocial Medicine, Clinic for Child and Adolescent Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Hamburg, Germany
J Clin Psychiatry 66:1239-46. 2005
..2) Comparison between those patients who shifted from DSM-IV schizophreniform disorder to schizophrenia or schizo-affective disorder and those whose diagnosis of schizophreniform disorder remained stable...
[Genetic findings in Attention-Deficit and Hyperactivity Disorder (ADHD)]Benno Graf Schimmelmann
Klinik fur Psychiatrie und Psychotherapie des Kindes und Jugendalters, Universitat Duisburg Essen, Rheinische Kliniken Essen, Virchowstrasse 174, DE 45147 Essen
Z Kinder Jugendpsychiatr Psychother 34:425-33. 2006
..The understanding of ADHD's neurobiology may be advanced by new technologies, such as SNP-based genome scans performed with gene chips comprising 10,000-1,000,000 SNPs, as well as using more sophisticated animal model designs...
Predictors of service disengagement in first-admitted adolescents with psychosisBenno Graf Schimmelmann
Department of Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg Essen, Germany
J Am Acad Child Adolesc Psychiatry 45:990-9. 2006
..To assess the risk and predictors of service disengagement in adolescents with first-episode psychosis (FEP) receiving their first treatment in a long-standing early intervention and prevention centre...
Long-term patterns of subjective wellbeing in schizophrenia: cluster, predictors of cluster affiliation, and their relation to recovery criteria in 2842 patients followed over 3 yearsMartin Lambert
Psychosis Centre, Centre for Psychosocial Medicine, Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Germany
Schizophr Res 107:165-72. 2009
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Attention-deficit hyperactivity disorder (ADHD) and glial integrity: S100B, cytokines and kynurenine metabolism--effects of medicationRobert D Oades
Clinic for Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg Essen, Essen, Germany
Behav Brain Funct 6:29. 2010
..This could be explained in terms of an impaired glial supply of energy to support neuronal activity...
Differential 3-year effects of first- versus second-generation antipsychotics on subjective well-being in schizophrenia using marginal structural modelsMartin Lambert
Psychosis Centre, Department of Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Centre Hamburg Eppendorf, Germany
J Clin Psychopharmacol 31:226-30. 2011
..This study examined the differential effects of first- (FGAs) versus second-generation antipsychotics (SGAs) on subjective well-being in patients with schizophrenia...
Subjective wellbeing under quetiapine treatment: effect of diagnosis, mood state, and anxietyMartin Lambert
Psychosis Early Detection and Intervention Centre PEDIC, Centre for Psychosocial Medicine, Department of Psychiatry, University Medical Center Hamburg Eppendorf, Germany
Schizophr Res 110:72-9. 2009
..To examine the effect of diagnosis, mood state, and anxiety on subjective wellbeing in patients with affective and non-affective psychotic disorders treated with quetiapine IR...
Differentiating schizoaffective and bipolar I disorder in first-episode psychotic maniaDaniel Schottle
Psychosis Early Detection and Intervention Centre PEDIC, Centre for Psychosocial Medicine, Department for Psychiatry and Psychotherapy, University Medical Centre Hamburg Eppendorf, Germany
Schizophr Res 140:31-6. 2012
..This study aims to differentiate schizoaffective disorder (SAD) and bipolar-I-disorder (BD) in first-episode psychotic mania (FEPM)...
Validation of a Clinical Global Impression Scale for Aggression (CGI-A) in a sample of 558 psychiatric patientsChristian G Huber
Psychosis Early Detection and Intervention Centre, Centre for Psychosocial Medicine, Department of Psychiatry and Psychotherapy, University Medical Centre Hamburg Eppendorf, Germany
Schizophr Res 100:342-8. 2008
..Clinical management of aggression depends on the availability of easily administrable measurements allowing reliable evaluation. The present study's aim is to validate a Clinical Global Impression-Severity of Aggression scale (CGI-A)...
Comparing the prodrome of schizophrenia-spectrum psychoses and affective disorders with and without psychotic featuresFrauke Schultze-Lutter
University Hospital of Child and Adolescent Psychiatry, University of Bern, Bolligenstr 111, 3000 Bern 60, Switzerland
Schizophr Res 138:218-22. 2012
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Prevalence, predictors, and consequences of long-term refusal of antipsychotic treatment in first-episode psychosisMartin Lambert
Psychosis Early Detection and Intervention Centre, Department of Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany
J Clin Psychopharmacol 30:565-72. 2010
..The present study aims to assess the prevalence and predictors of such a "medication refusal" subgroup and its association with illness outcome...
Association of subjective well-being, symptoms, and side effects with compliance after 12 months of treatment in schizophreniaAnne Karow
Center for Psychosocial Medicine, Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Hamburg, Germany
J Clin Psychiatry 68:75-80. 2007
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Basic symptoms and the prediction of first-episode psychosisFrauke Schultze-Lutter
University Hospital of Child and Adolescent Psychiatry, Bern, Switzerland
Curr Pharm Des 18:351-7. 2012
..Further, they appear to be sufficiently frequent prior to onset of the first psychotic episode as well as sufficiently rare in persons of general population to be considered as valuable for an early detection of psychosis...
Cost-effectiveness of 12-month therapeutic assertive community treatment as part of integrated care versus standard care in patients with schizophrenia treated with quetiapine immediate release (ACCESS trial)Anne Karow
Department of Psychiatry and Psychotherapy, Psychosis Centre, Centre for Psychosocial Medicine, University Medical Center Hamburg Eppendorf, Germany
J Clin Psychiatry 73:e402-8. 2012
..ACT was specifically developed for patients with schizophrenia, delivered by psychosis experts highly trained in respective psychotherapies, and embedded into an integrated care system...
Child and adolescent psychiatric geneticsJohannes Hebebrand
Department of Child and Adolescent Psychiatry, LVR Klinikum Essen, University of Duisburg Essen, Virchowstrasse 174, Essen, Germany
Eur Child Adolesc Psychiatry 19:259-79. 2010
..This review represents the introductory article of this special issue of the European Child and Adolescent Psychiatry...
From nature versus nurture, via nature and nurture, to gene x environment interaction in mental disordersAnne Kathrin Wermter
Department of Child and Adolescent Psychiatry and Psychotherapy, Philipps University of Marburg, Hans Sachs Strasse 6, Marburg, Germany
Eur Child Adolesc Psychiatry 19:199-210. 2010
..In future we need larger, sufficiently powered studies that include a detailed and sophisticated characterization of both phenotype and the environmental risk...
Assertive community treatment as part of integrated care versus standard care: a 12-month trial in patients with first- and multiple-episode schizophrenia spectrum disorders treated with quetiapine immediate release (ACCESS trial)Martin Lambert
Psychosis Centre, Department for Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
J Clin Psychiatry 71:1313-23. 2010
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Genome-wide association study in German patients with attention deficit/hyperactivity disorderAnke Hinney
Department of Child and Adolescent Psychiatry, University of Duisburg Essen, Essen, Germany
Am J Med Genet B Neuropsychiatr Genet 156:888-97. 2011
..The second best SNP is located in an intron of GRM5, a gene located within a recently described region with an infrequent copy number variation in patients with ADHD...
Prediction of remission as a combination of symptomatic and functional remission and adequate subjective well-being in 2960 patients with schizophreniaMartin Lambert
Psychosis Early Detection and Intervention Centre PEDIC, Centre for Psychosocial Medicine, Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Hamburg, Germany
J Clin Psychiatry 67:1690-7. 2006
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'A rose is a rose is a rose', but at-risk criteria differFrauke Schultze-Lutter
University Hospital of Child and Adolescence Psychiatry, University of Bern, Bern, Switzerland
Psychopathology 46:75-87. 2013
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Attention-deficit hyperactivity disorder (ADHD) and glial integrity: an exploration of associations of cytokines and kynurenine metabolites with symptoms and attentionRobert D Oades
Clinic for Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg Essen, 45147 Essen, Germany
Behav Brain Funct 6:32. 2010
..Therefore we examined predictions of biochemical associations with the major symptom clusters, measures of attention and response variability...
Associations among the perceived parent-child relationship, eating behavior, and body weight in preadolescents: results from a community-based sampleMelanie Schuetzmann
Asklepios Clinic Harburg, Department of Child and Adolescent Psychiatry and Psychotherapy, Eissendorfer Pferdeweg 52, 21075 Hamburg, Germany
J Pediatr Psychol 33:772-82. 2008
..The aim of our study was to replicate the finding from clinical samples that families of overweight children demonstrate adverse characteristics of the parent-child relationship...
Huntington disease: a case study of early onset presenting as depressionPia Duesterhus
Department of Child and Adolescent Psychiatry, Hamburg, Germany
J Am Acad Child Adolesc Psychiatry 43:1293-7. 2004
..It is important to be aware of hereditary conditions such as Huntington disease and to provide family counseling before genetic testing and after the diagnosis is confirmed...