Eric Schiffer

Summary

Publications

  1. ncbi CE - a multifunctional application for clinical diagnosis
    Maike Sniehotta
    Mosaiques Diagnostics and Therapeutics AG, Hannover, Germany
    Electrophoresis 28:1407-17. 2007
  2. ncbi Biomarkers for prostate cancer
    Eric Schiffer
    Mosaiques Diagnostics and Therapeutics AG, Mellendorfer Str 7 9, 30625 Hannover, Germany
    World J Urol 25:557-62. 2007
  3. ncbi Urinary proteome analysis for prostate cancer diagnosis: cost-effective application in routine clinical practice in Germany
    Eric Schiffer
    Mosaiques diagnostics GmbH, Germany
    Int J Urol 19:118-25. 2012
  4. ncbi Exploring the uremic toxins using proteomic technologies
    Eric Schiffer
    Mosaiques Diagnostics and Therapeutics, Hanover, Germany
    Contrib Nephrol 160:159-71. 2008
  5. ncbi Proteomics in gerontology: current applications and future aspects--a mini-review
    E Schiffer
    Mosaiques Diagnostics and Therapeutics AG, Hannover, Germany
    Gerontology 55:123-37. 2009
  6. ncbi The 2nd annual oncology biomarkers conference
    Eric Schiffer
    Mosaiques diagnostics GmbH, Mellendorfer Strasse 7 9, D 30625 Hannover, Germany
    Biomark Med 3:203-9. 2009
  7. ncbi Urinary proteome analysis to exclude severe vesicoureteral reflux
    Jens Drube
    Clinic of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    Pediatrics 129:e356-63. 2012
  8. ncbi High resolution proteome/peptidome analysis of body fluids by capillary electrophoresis coupled with MS
    Eric Schiffer
    Mosaiques Diagnostics and Therapeutics AG, Hanover, Germany
    Proteomics 6:5615-27. 2006
  9. ncbi Urinary excretion of twenty peptides forms an early and accurate diagnostic pattern of acute kidney injury
    Jochen Metzger
    Mosaiques diagnostics GmbH, Hannover, Germany
    Kidney Int 78:1252-62. 2010
  10. ncbi Urinary proteome analysis identifies infants but not older children requiring pyeloplasty
    Jens Drube
    Department of Pediatric Kidney, Liver and Metabolic Diseases, Children s Hospital, Hannover Medical School, Hannover, Germany
    Pediatr Nephrol 25:1673-8. 2010

Detail Information

Publications25

  1. ncbi CE - a multifunctional application for clinical diagnosis
    Maike Sniehotta
    Mosaiques Diagnostics and Therapeutics AG, Hannover, Germany
    Electrophoresis 28:1407-17. 2007
    ..In this report, we present a technical overview of various CE techniques and discuss their applications in clinical medicine...
  2. ncbi Biomarkers for prostate cancer
    Eric Schiffer
    Mosaiques Diagnostics and Therapeutics AG, Mellendorfer Str 7 9, 30625 Hannover, Germany
    World J Urol 25:557-62. 2007
    ..Some of the identified markers have the potential to yield novel prognostic tools for PCa, provide novel insights into its pathophysiology, and contribute to the establishment of novel treatment strategies...
  3. ncbi Urinary proteome analysis for prostate cancer diagnosis: cost-effective application in routine clinical practice in Germany
    Eric Schiffer
    Mosaiques diagnostics GmbH, Germany
    Int J Urol 19:118-25. 2012
    ..The aim of the present study was to report our experience with routine application of this test in clinical practice and its cost-effectiveness...
  4. ncbi Exploring the uremic toxins using proteomic technologies
    Eric Schiffer
    Mosaiques Diagnostics and Therapeutics, Hanover, Germany
    Contrib Nephrol 160:159-71. 2008
    ..Subsequently, examples of the application of proteomic techniques to define novel biomarkers for renal diseases and uremic toxins will be discussed...
  5. ncbi Proteomics in gerontology: current applications and future aspects--a mini-review
    E Schiffer
    Mosaiques Diagnostics and Therapeutics AG, Hannover, Germany
    Gerontology 55:123-37. 2009
    ..Aging is closely related to the onset of chronic diseases, such as coronary artery disease, diabetic nephropathy or different types of malignancies, reflecting the demand for novel biomarkers to manage theses diseases...
  6. ncbi The 2nd annual oncology biomarkers conference
    Eric Schiffer
    Mosaiques diagnostics GmbH, Mellendorfer Strasse 7 9, D 30625 Hannover, Germany
    Biomark Med 3:203-9. 2009
    ..They spoke on how biomarkers can be used to fast track the development of novel cancer drugs and how prognostic markers can lead towards early detection and treatment in personalized medicine approaches...
  7. ncbi Urinary proteome analysis to exclude severe vesicoureteral reflux
    Jens Drube
    Clinic of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    Pediatrics 129:e356-63. 2012
    ..We therefore aimed at establishing a noninvasive test to identify children with high-grade VUR...
  8. ncbi High resolution proteome/peptidome analysis of body fluids by capillary electrophoresis coupled with MS
    Eric Schiffer
    Mosaiques Diagnostics and Therapeutics AG, Hanover, Germany
    Proteomics 6:5615-27. 2006
    ..We also discuss clinical applications of the technology for the diagnosis of renal diseases, urogenital cancer, and arteriosclerosis as well as monitoring the responses to therapeutic interventions...
  9. ncbi Urinary excretion of twenty peptides forms an early and accurate diagnostic pattern of acute kidney injury
    Jochen Metzger
    Mosaiques diagnostics GmbH, Hannover, Germany
    Kidney Int 78:1252-62. 2010
    ....
  10. ncbi Urinary proteome analysis identifies infants but not older children requiring pyeloplasty
    Jens Drube
    Department of Pediatric Kidney, Liver and Metabolic Diseases, Children s Hospital, Hannover Medical School, Hannover, Germany
    Pediatr Nephrol 25:1673-8. 2010
    ..Based on our results, the proteome pattern established by Decramer and co-workers predicts the need for surgery in infants but not in older children with UPJO...
  11. ncbi Prediction of muscle-invasive bladder cancer using urinary proteomics
    Eric Schiffer
    Mosaiques Diagnostics and Therapeutics, Hannover, Germany
    Clin Cancer Res 15:4935-43. 2009
    ..Minimally invasive methods of predicting the risk of muscle-invasive urothelial bladder carcinoma may expedite appropriate therapy and reduce morbidity and cost...
  12. ncbi Quantitative urinary proteome analysis for biomarker evaluation in chronic kidney disease
    Justyna Jantos-Siwy
    Mosaiques Diagnostics and Therapeutics, Hannover, Germany
    J Proteome Res 8:268-81. 2009
    ..The calculation of absolute concentrations via exogenous stable isotope-labeled peptide standards is of no additional benefit...
  13. ncbi Capillary electrophoresis coupled to mass spectrometry for proteomic profiling of human urine and biomarker discovery
    Petra Zurbig
    Mosaiques diagnostics GmbH, Mellendorfer Str 7 9, 30625 Hannover, Germany
    Methods Mol Biol 564:105-21. 2009
    ..In this chapter, we discuss materials and methods for CE-MS-based clinical proteomics allowing the reproducible profiling of urine...
  14. ncbi Challenges of using mass spectrometry as a bladder cancer biomarker discovery platform
    Eric Schiffer
    Mosaiques Diagnostics and Therapeutics AG, Hannover, Germany
    World J Urol 26:67-74. 2008
    ..In consequence, the necessity of repeated screening for reappearance demonstrates the urgent need for novel biomarkers as alternatives to invasive standard procedures...
  15. ncbi Proteomic patterns predict acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
    Eva M Weissinger
    Hannover Medical School, Department of Hematology, Hemostasis, and Oncology, Hannover, Germany
    Blood 109:5511-9. 2007
    ..1% (95% CI 73.1 to 87.9) and a specificity of 75.6% (95% CI 71.6 to 79.4). Thus, high-resolution proteome analysis represents an unbiased laboratory-based screening method, enabling diagnosis, and possibly enabling preemptive therapy...
  16. ncbi Diagnosis of subclinical and clinical acute T-cell-mediated rejection in renal transplant patients by urinary proteome analysis
    Jochen Metzger
    Mosaiques diagnostics GmbH, Hannover, Germany
    Proteomics Clin Appl 5:322-33. 2011
    ..Noninvasive diagnosis of acute renal allograft rejection may be advantageous compared with the allograft biopsy...
  17. ncbi Urinary proteome pattern in children with renal Fanconi syndrome
    Jens Drube
    Department of Paediatric Nephrology, Children s Hospital, Hannover Medical School, Hannover, Germany
    Nephrol Dial Transplant 24:2161-9. 2009
    ..We studied the urinary low-molecular-weight proteome to identify excreted peptides indicative of a pathogenetic mechanism leading to tubular dysfunction...
  18. ncbi Bile proteomic profiles differentiate cholangiocarcinoma from primary sclerosing cholangitis and choledocholithiasis
    Tim O Lankisch
    Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany
    Hepatology 53:875-84. 2011
    ..This method may become a diagnostic tool in future as it offers a new possibility to diagnose malignant bile duct disease and thus enables efficient therapy particularly in patients with PSC...
  19. ncbi Markers of vascular disease in plasma from patients with chronic kidney disease identified by proteomic analysis
    Eric Schiffer
    Mosaiques diagnostics GmbH, Hannover, Germany
    J Hypertens 29:783-90. 2011
    ..Arterial calcification and aortic stiffness are currently used as surrogates for vascular alterations. However, still little is known about prediction and the patho-physiologic mechanisms leading to CVD...
  20. ncbi Urinary biomarkers of IgA nephropathy and other IgA-associated renal diseases
    Bruce A Julian
    Department of Medicine, University of Alabama at Birmingham, 1530 Third Avenue South, Birmingham, AL 35294, USA
    World J Urol 25:467-76. 2007
    ....
  21. ncbi [New method for early detection. Urine test for prostate carcinoma (interview by Dr. Christina Berndt)]
    Eric Schiffer
    MMW Fortschr Med 149:18. 2007
  22. ncbi Urinary proteomic biomarkers in coronary artery disease
    Lukas U Zimmerli
    British Heart Foundation BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow G12 8TA, United Kingdom
    Mol Cell Proteomics 7:290-8. 2008
    ..The workflow is amenable to clinical routine testing suggesting that non-invasive proteomics analysis can become a valuable addition to other biomarkers used in cardiovascular risk assessment...
  23. ncbi Electrophoretic methods for analysis of urinary polypeptides in IgA-associated renal diseases
    Bruce A Julian
    Division of Nephrology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Electrophoresis 28:4469-83. 2007
    ....
  24. ncbi Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease
    Hong Jiang
    Institute of Molecular Medicine and Max Planck Research Group on Stem Cell Aging and Department of Internal Medicine III, University of Ulm, 89081 Ulm, Germany
    Proc Natl Acad Sci U S A 105:11299-304. 2008
    ..These results support the concept that telomere dysfunction and DNA damage are interconnected pathways that are activated during human aging and disease...