D M Schellenberg

Summary

Publications

  1. pmc Varying efficacy of intermittent preventive treatment for malaria in infants in two similar trials: public health implications
    Clara Menendez
    Barcelona Center for International Health Research CRESIB, Hospital Clinic, Institut d Investigacions Biomedicas August Pi i Sunyer IDIBAPS, Universitat de Barcelona, Spain
    Malar J 6:132. 2007
  2. ncbi request reprint Intermittent preventive antimalarial treatment for Tanzanian infants: follow-up to age 2 years of a randomised, placebo-controlled trial
    David Schellenberg
    Centre for International Health, Institut d Investigacions Biomedicas August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
    Lancet 365:1481-3. 2005
  3. ncbi request reprint The IPTi Consortium: research for policy and action
    David Schellenberg
    Department of Infectious Diseases, London School of Hygiene and Tropical Medicine, University of London, Keppel Street, London WC1E 7HT, UK
    Trends Parasitol 22:296-300. 2006
  4. ncbi request reprint Current issues for anti-malarial drugs to control P. falciparum malaria
    D Schellenberg
    London School of Hygiene and Tropical Medicine, Department of Infectious Diseases, Keppel Street, London WC1E 7HT, UK
    Curr Mol Med 6:253-60. 2006
  5. ncbi request reprint The incidence of clinical malaria detected by active case detection in children in Ifakara, southern Tanzania
    D M Schellenberg
    Centro de Salud International, Institut d Investigacions Biomedicas August Pi i Sunyer IDIBAPS, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain
    Trans R Soc Trop Med Hyg 97:647-54. 2003
  6. ncbi request reprint A randomized comparison of two anemia treatment regimens in Tanzanian children
    David Schellenberg
    Centre for International Health, Institut d Investigacions Biomedicas August Pi i Sunyer, Hospital Clinic, Villarroel 170, Barcelona 08036, Spain
    Am J Trop Med Hyg 71:428-33. 2004
  7. pmc The silent burden of anaemia in Tanzanian children: a community-based study
    D Schellenberg
    Ifakara Health Research and Development Centre, Ifakara, United Republic of Tanzania
    Bull World Health Organ 81:581-90. 2003
  8. ncbi request reprint The changing epidemiology of malaria in Ifakara Town, southern Tanzania
    David Schellenberg
    Centre for International Health, Institut de Investigaciones Biomedicas August Pi I Sunyer, Barcelona, Spain
    Trop Med Int Health 9:68-76. 2004
  9. ncbi request reprint Randomised placebo-controlled trial of iron supplementation and malaria chemoprophylaxis for prevention of severe anaemia and malaria in Tanzanian infants
    C Menendez
    Unidad de Epidemiologia y Bioestadistica, Hospital Clinic, Barcelona, Spain
    Lancet 350:844-50. 1997
  10. doi request reprint Efficacy and safety of intermittent preventive treatment with sulfadoxine-pyrimethamine for malaria in African infants: a pooled analysis of six randomised, placebo-controlled trials
    John J Aponte
    Barcelona Centre for International Health Research, Hospital Clinic, University of Barcelona, Barcelona, Spain
    Lancet 374:1533-42. 2009

Collaborators

Detail Information

Publications33

  1. pmc Varying efficacy of intermittent preventive treatment for malaria in infants in two similar trials: public health implications
    Clara Menendez
    Barcelona Center for International Health Research CRESIB, Hospital Clinic, Institut d Investigacions Biomedicas August Pi i Sunyer IDIBAPS, Universitat de Barcelona, Spain
    Malar J 6:132. 2007
    ..Understanding the reasons for the discrepant results will help to elucidate the action mechanism of this intervention, which is essential for rational policy formulation...
  2. ncbi request reprint Intermittent preventive antimalarial treatment for Tanzanian infants: follow-up to age 2 years of a randomised, placebo-controlled trial
    David Schellenberg
    Centre for International Health, Institut d Investigacions Biomedicas August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
    Lancet 365:1481-3. 2005
    ....
  3. ncbi request reprint The IPTi Consortium: research for policy and action
    David Schellenberg
    Department of Infectious Diseases, London School of Hygiene and Tropical Medicine, University of London, Keppel Street, London WC1E 7HT, UK
    Trends Parasitol 22:296-300. 2006
    ..This review summarizes the available information on IPTi and presents the consortium's approach to determining whether IPTi might be a valuable additional strategy in programs to control malaria...
  4. ncbi request reprint Current issues for anti-malarial drugs to control P. falciparum malaria
    D Schellenberg
    London School of Hygiene and Tropical Medicine, Department of Infectious Diseases, Keppel Street, London WC1E 7HT, UK
    Curr Mol Med 6:253-60. 2006
    ....
  5. ncbi request reprint The incidence of clinical malaria detected by active case detection in children in Ifakara, southern Tanzania
    D M Schellenberg
    Centro de Salud International, Institut d Investigacions Biomedicas August Pi i Sunyer IDIBAPS, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain
    Trans R Soc Trop Med Hyg 97:647-54. 2003
    ....
  6. ncbi request reprint A randomized comparison of two anemia treatment regimens in Tanzanian children
    David Schellenberg
    Centre for International Health, Institut d Investigacions Biomedicas August Pi i Sunyer, Hospital Clinic, Villarroel 170, Barcelona 08036, Spain
    Am J Trop Med Hyg 71:428-33. 2004
    ..06). Compliance was satisfactory in only 39% (82 of 209) of the children in the first week of treatment. Extending the duration of therapy and improving compliance may have health benefits for anemic children in malaria-endemic settings...
  7. pmc The silent burden of anaemia in Tanzanian children: a community-based study
    D Schellenberg
    Ifakara Health Research and Development Centre, Ifakara, United Republic of Tanzania
    Bull World Health Organ 81:581-90. 2003
    ..To document the prevalence, age-distribution, and risk factors for anaemia in Tanzanian children less than 5 years old, thereby assisting in the development of effective strategies for controlling anaemia...
  8. ncbi request reprint The changing epidemiology of malaria in Ifakara Town, southern Tanzania
    David Schellenberg
    Centre for International Health, Institut de Investigaciones Biomedicas August Pi I Sunyer, Barcelona, Spain
    Trop Med Int Health 9:68-76. 2004
    ..Even in low/moderate malaria transmission settings, where older children suffer most malaria episodes, targeting effective malaria control at infants may produce important reductions in infant mortality caused by malaria...
  9. ncbi request reprint Randomised placebo-controlled trial of iron supplementation and malaria chemoprophylaxis for prevention of severe anaemia and malaria in Tanzanian infants
    C Menendez
    Unidad de Epidemiologia y Bioestadistica, Hospital Clinic, Barcelona, Spain
    Lancet 350:844-50. 1997
    ..We undertook a randomised comparison of different strategies for control of anaemia and malaria in infants, including an assessment of the effect of iron supplementation on malaria susceptibility...
  10. doi request reprint Efficacy and safety of intermittent preventive treatment with sulfadoxine-pyrimethamine for malaria in African infants: a pooled analysis of six randomised, placebo-controlled trials
    John J Aponte
    Barcelona Centre for International Health Research, Hospital Clinic, University of Barcelona, Barcelona, Spain
    Lancet 374:1533-42. 2009
    ..Intermittent preventive treatment (IPT) is a promising strategy for malaria control in infants. We undertook a pooled analysis of the safety and efficacy of IPT in infants (IPTi) with sulfadoxine-pyrimethamine in Africa...
  11. pmc From strategy development to routine implementation: the cost of Intermittent Preventive Treatment in Infants for malaria control
    Fatuma Manzi
    Ifakara Health Research and Development Centre, Ifakara, Tanzania
    BMC Health Serv Res 8:165. 2008
    ..Although efficacy information is available for many interventions, there is a dearth of data on the resources required for scaling up of health interventions...
  12. pmc Age interactions in the development of naturally acquired immunity to Plasmodium falciparum and its clinical presentation
    John J Aponte
    Barcelona Centre for International Health Research, Hospital Clinic IDIBAPS, Universitat de Barcelona, Barcelona, Spain
    PLoS Med 4:e242. 2007
    ..We investigated the role of age in disease incidence and the effects of chemoprophylaxis on clinical immunity development to Plasmodium falciparum during a randomised controlled trial...
  13. ncbi request reprint The safety and efficacy of sulfadoxine-pyrimethamine, amodiaquine, and their combination in the treatment of uncomplicated Plasmodium falciparum malaria
    David Schellenberg
    Unidad de Epidemiologia, Hospital Clinic, Barcelona, Spain
    Am J Trop Med Hyg 67:17-23. 2002
    ..6% vs. SP 29.9%; P = 0.001). The level of R1 resistance to SP may herald a rapid decline in its efficacy as SP drug pressure increases. Coadministration of AQ+SP may delay this...
  14. ncbi request reprint Effectiveness and cost of facility-based Integrated Management of Childhood Illness (IMCI) in Tanzania
    Joanna R M Armstrong Schellenberg
    Ifakara Health Research and Development Centre, Ifakara, Tanzania
    Lancet 364:1583-94. 2004
    ..We assessed the effectiveness of facility-based IMCI in rural Tanzania...
  15. ncbi request reprint Risk factors for presentation to hospital with severe anaemia in Tanzanian children: a case-control study
    Elizeus Kahigwa
    Ifakara Health Research and Development Centre, Ifakara, Tanzania
    Trop Med Int Health 7:823-30. 2002
    ..The concentration of anaemia in infants and problems of access to health services and adequate case management underline the need for targeted preventive strategies for anaemia control...
  16. ncbi request reprint The effects of short-term iron supplementation on iron status in infants in malaria-endemic areas
    Clara Menendez
    Center for International Health y Departamento de Bioquimica ClĂ­nica Institut d Investigacions Biome diques August Pi i Sunyer Hospital Clinic, Villarroeal 170, E 08036, Barcelona, Spain
    Am J Trop Med Hyg 71:434-40. 2004
    ..7% versus 37.3% at 12 months of age). We concluded that iron supplementation between the ages of 2-6 months improves iron status at least up to 12 months of age. Malaria infection does not contribute to iron deficiency...
  17. pmc The acceptability of intermittent preventive treatment of malaria in infants (IPTi) delivered through the expanded programme of immunization in southern Tanzania
    Robert Pool
    London School of Hygiene and Tropical Medicine, London, UK
    Malar J 7:213. 2008
    ..This paper reports on the reception of IPTi during the first implementation study of IPTi in southern Tanzania...
  18. pmc Health and survival of young children in southern Tanzania
    Joanna R M Armstrong Schellenberg
    Ifakara Health Research and Development Centre, Ifakara, Tanzania
    BMC Public Health 8:194. 2008
    ..With a view to developing health systems strategies to improve reach to high-risk groups, we present information on health and survival from household and health facility perspectives in five districts of southern Tanzania...
  19. pmc The age patterns of severe malaria syndromes in sub-Saharan Africa across a range of transmission intensities and seasonality settings
    Arantxa Roca-Feltrer
    Department of Disease Control, Faculty of Infectious and Tropical Disease, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK
    Malar J 9:282. 2010
    ..A greater understanding of the relationship between transmission intensity, seasonality and the age-pattern of malaria is needed to guide appropriate targeting of malaria interventions in different epidemiological settings...
  20. ncbi request reprint Malaria infection does not appear to modify the risk of bronchiolitis early in life
    Clara Menendez
    Unidad de Epidemiologia y Bioestadistica, Institut d Investigaciones Mediques August Pi i Sunyer, Hospital Clinic, Barcelona, Spain
    Pediatr Infect Dis J 21:249-54. 2002
    ..Information on the role of parasites in this context is limited. Bronchiolitis in infancy has been linked with asthmatic symptoms later in childhood, although the underlying cause of this association is unknown...
  21. pmc Modelling the impact of intermittent preventive treatment for malaria on selection pressure for drug resistance
    Neal Alexander
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Malar J 6:9. 2007
    ..Intermittent preventive treatment (IPT) is a promising intervention for malaria control, although there are concerns about its impact on drug resistance...
  22. ncbi request reprint Inequities among the very poor: health care for children in rural southern Tanzania
    Joanna Armstrong Schellenberg
    Ifakara Health Research and Development Centre, Ifakara, Tanzania
    Lancet 361:561-6. 2003
    ..We sought evidence of inequities in health care by sex and socioeconomic status for young children living in a poor rural area of southern Tanzania...
  23. pmc How is childhood development of immunity to Plasmodium falciparum enhanced by certain antimalarial interventions?
    Colin J Sutherland
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK
    Malar J 6:161. 2007
    ....
  24. pmc Assessment of a national voucher scheme to deliver insecticide-treated mosquito nets to pregnant women
    Tanya Marchant
    London School of Hygiene and Tropical Medicine, London, UK
    CMAJ 182:152-6. 2010
    ..We aimed to identify potential ways to equitably improve overall coverage of the intervention...
  25. pmc Assessing agreement between malaria slide density readings
    Neal Alexander
    Tropical Epidemiology Group, Department of Epidemiology and Public Health, London School of Hygiene and Tropical Medicine, London, UK
    Malar J 9:4. 2010
    ..The current paper seeks a procedure which avoids the disadvantages of these current options and whose parameter values are more clearly justified...
  26. pmc Performance of HRP-2 based rapid diagnostic test for malaria and its variation with age in an area of intense malaria transmission in southern Tanzania
    Anne Laurent
    Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    Malar J 9:294. 2010
    ..As a result, test specificity may vary between age groups with different prevalence of P. falciparum infection...
  27. pmc Development of behaviour change communication strategy for a vaccination-linked malaria control tool in southern Tanzania
    Adiel K Mushi
    Ifakara Health Institute, P, O, Box 78373, Dar es Salaam, Tanzania
    Malar J 7:191. 2008
    ....
  28. ncbi request reprint Intermittent preventive treatment for malaria control in infants: moving towards evidence-based policy and public health action
    Andrea Egan
    Trop Med Int Health 10:815-7. 2005
  29. pmc Modelling the epidemiological impact of intermittent preventive treatment against malaria in infants
    Amanda Ross
    Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland
    PLoS ONE 3:e2661. 2008
    ..We investigated mechanisms proposed for the action of IPTi and made predictions of the likely impact on morbidity and mortality...
  30. ncbi request reprint Factors affecting home delivery in rural Tanzania
    Mwifadhi Mrisho
    Ifakara Health Research and Development Centre, Dar es Salaam, Tanzania
    Trop Med Int Health 12:862-72. 2007
    ..This study combines an understanding of gender issues relating to health and help-seeking behaviour with epidemiological knowledge concerning place of delivery...
  31. ncbi request reprint Evaluation of efficacy of community-based vs. institutional-based direct observed short-course treatment for the control of tuberculosis in Kilombero district, Tanzania
    Fred Lwilla
    District Health Office, Ifakara, Tanzania
    Trop Med Int Health 8:204-10. 2003
    ..23, 1.71 and OR = 1.58; 95% CI 0.32, 7.88, respectively] suggesting that CBDOT may be a viable alternative to IBDOT. CBDOT may be particularly useful in parts of the country where people live far from health facilities...
  32. ncbi request reprint Prevalence of different virulence factors and biofilm production in enteroaggregative Escherichia coli isolates causing diarrhea in children in Ifakara (Tanzania)
    Eva Mendez-Arancibia
    Servei de Microbiologia, Centre de Diagnostic Biomedic, Hospital Clinic, Facultat de Medicina, Universitat de Barcelona, Villarroel 170 08036 Barcelona, Spain
    Am J Trop Med Hyg 78:985-9. 2008
    ..032). These results again show the high heterogeneity of virulence factors among EAEC isolates causing diarrhea in children, and that biofilm may be an important virulence factor, strongly associated with the presence of AggR...
  33. doi request reprint Understanding home-based neonatal care practice in rural southern Tanzania
    Mwifadhi Mrisho
    Ifakara Health Research and Development Centre, Dar es Salaam, Tanzania
    Trans R Soc Trop Med Hyg 102:669-78. 2008
    ..Some neonates are denied colostrum, which is perceived as dirty. Behaviour-change communication efforts are needed to improve early newborn care practices...