Reisser C, Dick C, Kruglyak L, Botstein D, Schacherer J, Hess D. Genetic Basis of Ammonium Toxicity Resistance in a Sake Strain of Yeast: A Mendelian Case. G3 (Bethesda). 2013;3:733-740 pubmed publisher
..These findings further refine our understanding of ammonium toxicity in yeast and provide an example of using natural variation to understand cellular processes. ..
Jung P, Sigwalt A, Ohnuki S, De Montigny J, Ohya Y, Schacherer J. Large-Scale Survey of Intraspecific Fitness and Cell Morphology Variation in a Protoploid Yeast Species. G3 (Bethesda). 2016;6:1063-71 pubmed publisher
..kluyveri might be useful in further linkage mapping analyses of complex traits, and could ultimately provide a better insight into the evolution of the genotype-phenotype relationship across yeast species. ..
Hou J, Schacherer J. Negative epistasis: a route to intraspecific reproductive isolation in yeast?. Curr Genet. 2016;62:25-9 pubmed publisher
..These advances deepened our current understandings and opened further perspectives regarding the complete picture of molecular and evolutionary origins driving the onset of intraspecific reproductive isolation in yeasts. ..
Peter J, De Chiara M, Friedrich A, Yue J, Pflieger D, Bergström A, et al
. Genome evolution across 1,011 Saccharomyces cerevisiae isolates. Nature. 2018;556:339-344 pubmed publisher
..This resource will guide future population genomics and genotype-phenotype studies in this classic model system. ..
Freel K, Friedrich A, Hou J, Schacherer J. Population genomic analysis reveals highly conserved mitochondrial genomes in the yeast species Lachancea thermotolerans. Genome Biol Evol. 2014;6:2586-94 pubmed publisher
..kluyveri, demonstrating that the factors driving mt genome evolution are different even between closely related species. ..
Brion C, Pflieger D, Friedrich A, Schacherer J. Evolution of intraspecific transcriptomic landscapes in yeasts. Nucleic Acids Res. 2015;43:4558-68 pubmed publisher
..Our data set sheds an important light on the evolution of intraspecific transcriptomic variation across distant species. ..
Freel K, Friedrich A, Schacherer J. Mitochondrial genome evolution in yeasts: an all-encompassing view. FEMS Yeast Res. 2015;15:fov023 pubmed publisher
..Here, we summarize the present state of yeast mitogenomics, including the currently available data and what it reveals concerning the diversity of content, organization, structure and evolution of mt genomes. ..
Freel K, Friedrich A, Sarilar V, Devillers H, NeuvÃ©glise C, Schacherer J. Whole-Genome Sequencing and Intraspecific Analysis of the Yeast Species Lachancea quebecensis. Genome Biol Evol. 2016;8:733-41 pubmed publisher
..However, even with relatively similar ranges of genome divergence, L. quebecensis has an extremely low global phenotypic variance of 0.062 compared with 0.59 previously determined in S. cerevisiae. ..
Hou J, Schacherer J. On the Mapping of Epistatic Genetic Interactions in Natural Isolates: Combining Classical Genetics and Genomics. Methods Mol Biol. 2016;1361:345-60 pubmed publisher