Research Topics

Isabelle J Schalk



  1. Schalk I, Mislin G, Brillet K. Structure, function and binding selectivity and stereoselectivity of siderophore-iron outer membrane transporters. Curr Top Membr. 2012;69:37-66 pubmed publisher
    ..In some bacteria, TBDTs are also partners of signaling cascades regulating the expression of proteins involved in siderophore biosynthesis and siderophore-iron acquisition. ..
  2. Gasser V, Guillon L, Cunrath O, Schalk I. Cellular organization of siderophore biosynthesis in Pseudomonas aeruginosa: Evidence for siderosomes. J Inorg Biochem. 2015;148:27-34 pubmed publisher
    ..Here, we describe these recently published findings and discuss the existence of these siderosomes in P. aeruginosa. ..
  3. Cunrath O, Geoffroy V, Schalk I. Metallome of Pseudomonas aeruginosa: a role for siderophores. Environ Microbiol. 2016;18:3258-3267 pubmed publisher
    ..aeruginosa cells, thus preserving the equilibrium of the metallome in a polluted environment. ..
  4. Schalk I, Cunrath O. An overview of the biological metal uptake pathways in Pseudomonas aeruginosa. Environ Microbiol. 2016;18:3227-3246 pubmed publisher
    ..P. aeruginosa is a medically significant Gram-negative bacterial opportunistic pathogen that can cause severe chronic lung infections in cystic fibrosis patients and that is responsible for nosocomial infections worldwide. ..
  5. Schalk I, Guillon L. Pyoverdine biosynthesis and secretion in Pseudomonas aeruginosa: implications for metal homeostasis. Environ Microbiol. 2013;15:1661-73 pubmed publisher
    ..This review considers how these new insights into pyoverdine biosynthesis and secretion contribute to our understanding of the role of pyoverdine in iron and metal homeostasis in fluorescent Pseudomonads. ..
  6. Schalk I, Hannauer M, Braud A. New roles for bacterial siderophores in metal transport and tolerance. Environ Microbiol. 2011;13:2844-54 pubmed publisher
  7. Schalk I, Guillon L. Fate of ferrisiderophores after import across bacterial outer membranes: different iron release strategies are observed in the cytoplasm or periplasm depending on the siderophore pathways. Amino Acids. 2013;44:1267-77 pubmed publisher