Alexander M Scherbakov
Scherbakov A, Zavarzin I, Vorontsova S, Hajra A, Andreeva O, Yadykov A, et al
. Synthesis and evaluation of the antiproliferative activity of benzylidenes of 16-dehydroprogesterone series. Steroids. 2018;138:91-101 pubmed publisher
..The new class of antitumor compounds holds promise as the basis for the design of agents for cancer therapy. ..
Semina S, Scherbakov A, Vnukova A, Bagrov D, Evtushenko E, Safronova V, et al
. Exosome-Mediated Transfer of Cancer Cell Resistance to Antiestrogen Drugs. Molecules. 2018;23: pubmed publisher
..In general, we evaluate the established results as the evidence of the possible exosome involvement in the transferring of the hormone/metformin resistance in breast cancer cells. ..
Sorokin D, Scherbakov A, Yakushina I, Semina S, Gudkova M, Krasil nikov M. The Mechanism of Adaptation of Breast Cancer Cells to Hypoxia: Role of AMPK/mTOR Signaling Pathway. Bull Exp Biol Med. 2016;160:555-9 pubmed publisher
..These findings suggest that these proteins can be promising targets for targeted therapy of tumors developing under hypoxic conditions. ..
Scherbakov A, Gershtein E, Korotkova E, Ovchinnikova L, Ovsii O, Ermilova V, et al
. Regulatory Proteins of Epithelial-Mesenchymal Transition and Some Components of VEGF Signaling Pathway in Breast Cancer. Bull Exp Biol Med. 2016;160:802-6 pubmed publisher
..The data attest to coordinated activation of regulatory proteins of epithelial-mesenchymal transition and the major components of VEGF signaling pathway in breast tumors. ..
Scherbakov A, Andreeva O, Shatskaya V, Krasil nikov M. The relationships between snail1 and estrogen receptor signaling in breast cancer cells. J Cell Biochem. 2012;113:2147-55 pubmed publisher
Scherbakov A, Stefanova L, Sorokin D, Semina S, Berstein L, Krasil nikov M. Snail/beta-catenin signaling protects breast cancer cells from hypoxia attack. Exp Cell Res. 2013;319:3150-9 pubmed publisher
..Moreover, we suggest that the level of these proteins as well the level of AMPK phosphorylation may be considered as predictors of the tumor sensitivity to anti-angiogenic drugs. ..
Scherbakov A, Krasil nikov M, Kushlinskii N. Molecular mechanisms of hormone resistance of breast cancer. Bull Exp Biol Med. 2013;155:384-95 pubmed
..On the whole, the results indicate good prospects of using EGFR, HER-2/neu, mTOR, VEGFR, PI3K/Akt molecular pathways as targets for BC therapy, including therapy for BC resistant forms. ..