Hakan Savli

Summary

Publications

  1. ncbi request reprint Gene expression profiling of B-CLL in Ukrainian patients in post-Chernobyl period
    H Savli
    Medical Genetics Department, Medicine Faculty of Kocaeli University, Turkey
    Exp Oncol 34:57-63. 2012
  2. ncbi request reprint Quantitative real time PCR analysis of apoptosis-related gene expression in leukemias in Ukrainian patients
    H Savli
    Medical Genetics Department, Medicine Faculty of Kocaeli University, Turkey
    Exp Oncol 33:104-6. 2011
  3. pmc Gene network and canonical pathway analysis in prostate cancer: a microarray study
    Hakan Savli
    Department of Medical Genetics and Clinical Research Unit, Kocaeli University, Kocaeli 41380, Turkey
    Exp Mol Med 40:176-85. 2008
  4. ncbi request reprint The prevalence of CYP2C19 mutations in Turkish patients with dyspepsia
    Altay Celebi
    Kocaeli University, Faculty of Medicine Division of Gastroenterology 41380, Umuttepe, Kocaeli, Turkey
    Turk J Gastroenterol 20:161-4. 2009
  5. ncbi request reprint Real-Time PCR analysis of af4 and dek genes expression in acute promyelocytic leukemia t (15;17) patients
    Hakan Savli
    Department of Medical Biology, Medical Faculty, University of Kocaeli, Kocaeli, Turkey
    Exp Mol Med 36:279-82. 2004
  6. doi request reprint Vascular endothelial growth factor (VEGF) polymorphisms in HELLP syndrome patients determined by quantitative real-time PCR and melting curve analyses
    Balint Nagy
    1st Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary
    Clin Chim Acta 389:126-31. 2008
  7. ncbi request reprint The effect of stimulated microglia conditioned media on BDNF gene expression of striatal astrocytes: quantification by real-time PCR
    Hakan Savli
    Department of Medical Biology, Medical Faculty, University of Kocaeli, Turkey
    Int J Neurosci 114:1601-12. 2004
  8. ncbi request reprint Effect of carbapenems on the transcriptional expression of the oprD, oprM and oprN genes in Pseudomonas aeruginosa
    Fetiye Kolayli
    Mikrobiyoloji ve Klinik Mikrobiyoloji AD, KOU Tip Fakultesi, Sopali Ciftligi, 41900 Derince Kocaeli, Turkey
    J Med Microbiol 53:915-20. 2004
  9. ncbi request reprint Real-time PCR analysis of the apoptosis related genes in ATRA treated APL t(15;17) patients
    Hakan Savli
    Department of Medical Biology, Medical Faculty, University of Kocaeli, Kocaeli, Turkey
    Exp Mol Med 35:454-9. 2003
  10. ncbi request reprint Expression stability of six housekeeping genes: A proposal for resistance gene quantification studies of Pseudomonas aeruginosa by real-time quantitative RT-PCR
    Hakan Savli
    Tibbi Biyoloji AD, Kocaeli Universitesi, Tip Fakultesi, Sopali Ciftligi, 41900 Kocaeli, Turkey
    J Med Microbiol 52:403-8. 2003

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Gene expression profiling of B-CLL in Ukrainian patients in post-Chernobyl period
    H Savli
    Medical Genetics Department, Medicine Faculty of Kocaeli University, Turkey
    Exp Oncol 34:57-63. 2012
    ..We have analyzed gene expression patterns in Ukrainian B-CLL patients with the aim of identifying B-CLL involved / associated genes in order to shed light on the biology of this pathological entity...
  2. ncbi request reprint Quantitative real time PCR analysis of apoptosis-related gene expression in leukemias in Ukrainian patients
    H Savli
    Medical Genetics Department, Medicine Faculty of Kocaeli University, Turkey
    Exp Oncol 33:104-6. 2011
    ..The molecular biological analysis of malignant diseases of hematopoietic and lymphoid tissues in contaminated territories requires the precise diagnosis based on criteria of novel classifications...
  3. pmc Gene network and canonical pathway analysis in prostate cancer: a microarray study
    Hakan Savli
    Department of Medical Genetics and Clinical Research Unit, Kocaeli University, Kocaeli 41380, Turkey
    Exp Mol Med 40:176-85. 2008
    ..Our data provide not only networks between the genes for understanding the biologic properties of PCA but also useful pathway maps for future understanding of disease and the construction of new therapeutic targets...
  4. ncbi request reprint The prevalence of CYP2C19 mutations in Turkish patients with dyspepsia
    Altay Celebi
    Kocaeli University, Faculty of Medicine Division of Gastroenterology 41380, Umuttepe, Kocaeli, Turkey
    Turk J Gastroenterol 20:161-4. 2009
    ..We aimed to determine the distribution of cytochrome P450 2C19 (CYP2C19) genotype frequencies in Turkish patients with dyspepsia...
  5. ncbi request reprint Real-Time PCR analysis of af4 and dek genes expression in acute promyelocytic leukemia t (15;17) patients
    Hakan Savli
    Department of Medical Biology, Medical Faculty, University of Kocaeli, Kocaeli, Turkey
    Exp Mol Med 36:279-82. 2004
    ..Our study was the first attempt for analysing dek and af4 genes in APL t (15; 17) patients by quantitative Real-Time RT-PCR. This rapid and sensitive method could be used to screen these genes in different types of leukaemia...
  6. doi request reprint Vascular endothelial growth factor (VEGF) polymorphisms in HELLP syndrome patients determined by quantitative real-time PCR and melting curve analyses
    Balint Nagy
    1st Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary
    Clin Chim Acta 389:126-31. 2008
    ..Therefore, we decided to determine the allele and genotype frequencies of VEGF G+405C, C-460T and C-2578A SNPs in healthy pregnant women and HELLP syndrome patients...
  7. ncbi request reprint The effect of stimulated microglia conditioned media on BDNF gene expression of striatal astrocytes: quantification by real-time PCR
    Hakan Savli
    Department of Medical Biology, Medical Faculty, University of Kocaeli, Turkey
    Int J Neurosci 114:1601-12. 2004
    ..33 fold) when compared to astrocytes treated with regular medium or unstimulated striatal MCM. We have also seen the similar effect with cortical MCM implying that effect of MCM does not change with regionally different microglia...
  8. ncbi request reprint Effect of carbapenems on the transcriptional expression of the oprD, oprM and oprN genes in Pseudomonas aeruginosa
    Fetiye Kolayli
    Mikrobiyoloji ve Klinik Mikrobiyoloji AD, KOU Tip Fakultesi, Sopali Ciftligi, 41900 Derince Kocaeli, Turkey
    J Med Microbiol 53:915-20. 2004
    ..The responses at the mRNA level found here were unexpected and suggested a chaotic, unpredictable regulatory mechanism...
  9. ncbi request reprint Real-time PCR analysis of the apoptosis related genes in ATRA treated APL t(15;17) patients
    Hakan Savli
    Department of Medical Biology, Medical Faculty, University of Kocaeli, Kocaeli, Turkey
    Exp Mol Med 35:454-9. 2003
    ..Ratio of bcl2 to bax may be more important for this regulation than the ratio of bcl2 to bad. Either bcl2 family or less known apoptosis related genes as wt1 will still be required to further studies in this setting...
  10. ncbi request reprint Expression stability of six housekeeping genes: A proposal for resistance gene quantification studies of Pseudomonas aeruginosa by real-time quantitative RT-PCR
    Hakan Savli
    Tibbi Biyoloji AD, Kocaeli Universitesi, Tip Fakultesi, Sopali Ciftligi, 41900 Kocaeli, Turkey
    J Med Microbiol 52:403-8. 2003
    ....
  11. ncbi request reprint Gene expression analysis of 1,25(OH)2D3-dependent differentiation of HL-60 cells: a cDNA array study
    Hakan Savli
    Department of Pathology, Haartman Institute and Helsinki University Central Hospital, Helsinki, Finland
    Br J Haematol 118:1065-70. 2002
    ..To demonstrate the genes that initiate differentiation, sequential gene expression analysis has to be performed during the first 24 h of the differentiation process...