Improved approximations to scaling relationships for species, populations, and ecosystems across latitudinal and elevational gradientsVan M Savage
Santa Fe Institute, Santa Fe, NM 87501, USA
J Theor Biol 227:525-34. 2004
..Moreover, the improved approximation for the Boltzmann factor, which uses the average and standard deviation of temperature, is quite accurate and represents a significant improvement over previous approximations...
A general multi-trait-based framework for studying the effects of biodiversity on ecosystem functioningVan M Savage
Santa Fe Institute, Santa Fe, NM 87501, USA
J Theor Biol 247:213-29. 2007
..The methodological advances provided here will apply to almost any function that relates species traits and environmental drivers to growth, and should prove useful for studying the effects of climate change on the dynamics of biota...
Effects of body size and temperature on population growthVan M Savage
Santa Fe Institute, Santa Fe, New Mexico 87501, USA
Am Nat 163:429-41. 2004
..This theory links the rates of metabolism and resource use of individuals to life-history attributes and population dynamics for a broad assortment of organisms, from unicellular organisms to mammals...
A quantitative, theoretical framework for understanding mammalian sleepVan M Savage
Santa Fe Institute, 1399 Hyde Park Road, Santa Fe, NM 87501, USA
Proc Natl Acad Sci U S A 104:1051-6. 2007
..Data for 96 species of mammals, spanning six orders of magnitude in body size, are consistent with these predictions and provide strong evidence that time scales for sleep are set by the brain's, not the whole-body, metabolic rate...
Effects of size and temperature on developmental timeJames F Gillooly
Department of Biology, The University of New Mexico, Albuquerque, New Mexico 87131, USA
Nature 417:70-3. 2002
..Development in other animals at other life stages is also described by this model. These results suggest a general definition of biological time that is approximately invariant and common to all organisms...
Scaling of number, size, and metabolic rate of cells with body size in mammalsVan M Savage
Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA
Proc Natl Acad Sci U S A 104:4718-23. 2007
..Our results and conceptual framework emphasize fundamental constraints that link the structure and function of cells to that of whole organisms...
Kinetic effects of temperature on rates of genetic divergence and speciationAndrew P Allen
National Center for Ecological Analysis and Synthesis, 735 State Street, Suite 300, Santa Barbara, CA 93101, USA
Proc Natl Acad Sci U S A 103:9130-5. 2006
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Comment on "The illusion of invariant quantities in life histories"Van M Savage
Bauer Center for Genomics Research, Harvard University, Cambridge, MA 02138, USA
Science 312:198; author reply 198. 2006
..We show that their results are largely inconsequential for life history theory because the authors confound two definitions of invariance, and rigorous analysis of their null model demonstrates that it does not match observed data...
The metabolic basis of whole-organism RNA and phosphorus contentJames F Gillooly
Department of Biology, University of New Mexico, Albuquerque, NM 87131, USA
Proc Natl Acad Sci U S A 102:11923-7. 2005
..The model provides a framework for linking attributes of individuals to the storage and flux of phosphorus in ecosystems...
Physiology: Why does metabolic rate scale with body size?Geoffrey B West
Los Alamos National Laboratory, Los Alamos, New Mexico 87545, USA
Nature 421:713; discussion 714. 2003
Sizing up allometric scaling theoryVan M Savage
Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America
PLoS Comput Biol 4:e1000171. 2008
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