Faisal M Sanai

Summary

Country: Saudi Arabia

Publications

  1. pmc Liver abscess presentation and management in Saudi Arabia and the United Kingdom
    Ali Albenmousa
    Department of Medicine, Division of Gastroenterology and Hepatology, Riyadh Military Hospital, Riyadh, Saudi Arabia
    Ann Saudi Med 31:528-32. 2011
  2. ncbi Assessment of alpha-fetoprotein in the diagnosis of hepatocellular carcinoma in Middle Eastern patients
    Faisal M Sanai
    Department of Gastroenterology, Riyadh Military Hospital A41, PO Box 7897, Riyadh 11159, Saudi Arabia
    Dig Dis Sci 55:3568-75. 2010
  3. pmc Liver biopsy for histological assessment: The case against
    Faisal M Sanai
    Hepatology Unit, Department of Medicine, Riyadh Military Hospital, Riyadh, Saudi Arabia
    Saudi J Gastroenterol 16:124-32. 2010
  4. ncbi Hepatic granuloma: decreasing trend in a high-incidence area
    Faisal M Sanai
    Department of Medicine, Division of Gastroenterology and Hepatology, Riyadh Military Hospital, Riyadh, Saudi Arabia
    Liver Int 28:1402-7. 2008
  5. ncbi Is serum alanine transaminase level a reliable marker of histological disease in chronic hepatitis C infection?
    Faisal M Sanai
    Department of Medicine, Division of Gastroenterology and Hepatology, Riyadh Military Hospital, Riyadh, Saudi Arabia
    Liver Int 28:1011-8. 2008
  6. doi Prevalence and impact of hepatic steatosis on the response to antiviral therapy in Saudi patients with genotypes 1 and 4 chronic hepatitis C
    Abdallah M Alqaraawi
    Department of Medicine, College of Medicine, King Saud University, and Department of Pathology, Riyadh Military Hospital, P O Box 2925 59, Riyadh, 11461, Saudi Arabia
    Dig Dis Sci 56:1222-8. 2011
  7. ncbi Single nucleotide polymorphisms in CXCR1 gene and its association with hepatitis B infected patients in Saudi Arabia
    Fahad N Almajhdi
    Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia
    Ann Hepatol 12:220-7. 2013
  8. doi Relationship of interferon-γ-inducible protein-10 kDa with viral response in patients with various heterogeneities of hepatitis C virus genotype-4
    Hamad I Al-Ashgar
    Section of Gastroenterology, Department of Medicine, King Faisal Specialist Hospital and Research Centre KFSH and RC, Riyadh 11211, Saudi Arabia
    Eur J Gastroenterol Hepatol 25:404-10. 2013
  9. doi Genetic variation at -1878 (rs2596542) in MICA gene region is associated with chronic hepatitis B virus infection in Saudi Arabian patients
    Ahmed A Al-Qahtani
    Department of Infection and Immunity, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia Liver Disease Research Center, King Saud University, Riyadh, Saudi Arabia Electronic address
    Exp Mol Pathol 95:255-8. 2013
  10. ncbi Predictors of significant fibrosis in chronic hepatitis B patients with low viremia
    Ayman A Abdo
    College of Medicine, Liver Disease Research Center, King Saud University Department of Medicine, Liver Unit, Division of Gastroenterology and Hepatology, University of Calgary, AB, Canada Department of Gastroenterology, Riyadh Military Hospital, Riyadh Department of Medicine, Division of Gastroenterology, King Fahad General Hospital, Jeddah Department of Medicine, Division of Gastroenterology Department of Pathology, King Faisal Specialist Hospital and Research Center Departments of Pathology Hepatobiliary Sciences and Liver Transplantation, King Abdulaziz Medical City, Riyadh, Saudi Arabia
    J Clin Gastroenterol 48:e50-6. 2014

Collaborators

Detail Information

Publications30

  1. pmc Liver abscess presentation and management in Saudi Arabia and the United Kingdom
    Ali Albenmousa
    Department of Medicine, Division of Gastroenterology and Hepatology, Riyadh Military Hospital, Riyadh, Saudi Arabia
    Ann Saudi Med 31:528-32. 2011
    ..We compared the mode of presentation, risk factors, management and outcome of LA patients in Saudi Arabia with cases from the United Kingdom (UK)...
  2. ncbi Assessment of alpha-fetoprotein in the diagnosis of hepatocellular carcinoma in Middle Eastern patients
    Faisal M Sanai
    Department of Gastroenterology, Riyadh Military Hospital A41, PO Box 7897, Riyadh 11159, Saudi Arabia
    Dig Dis Sci 55:3568-75. 2010
    ..No data exists for this test in the Middle Eastern population. In addition, there is limited data on the impact of virological status on AFP levels...
  3. pmc Liver biopsy for histological assessment: The case against
    Faisal M Sanai
    Hepatology Unit, Department of Medicine, Riyadh Military Hospital, Riyadh, Saudi Arabia
    Saudi J Gastroenterol 16:124-32. 2010
    ....
  4. ncbi Hepatic granuloma: decreasing trend in a high-incidence area
    Faisal M Sanai
    Department of Medicine, Division of Gastroenterology and Hepatology, Riyadh Military Hospital, Riyadh, Saudi Arabia
    Liver Int 28:1402-7. 2008
    ..Hepatic granuloma (HG) has a high reported incidence in Saudi Arabia (14.6%). We aimed to identify the incidence of HG in our centres and review its presenting features and underlying aetiology...
  5. ncbi Is serum alanine transaminase level a reliable marker of histological disease in chronic hepatitis C infection?
    Faisal M Sanai
    Department of Medicine, Division of Gastroenterology and Hepatology, Riyadh Military Hospital, Riyadh, Saudi Arabia
    Liver Int 28:1011-8. 2008
    ..These patients are described to have a mild degree of histological liver damage. We aimed to assess the histological liver changes in HCV patients with PNALT...
  6. doi Prevalence and impact of hepatic steatosis on the response to antiviral therapy in Saudi patients with genotypes 1 and 4 chronic hepatitis C
    Abdallah M Alqaraawi
    Department of Medicine, College of Medicine, King Saud University, and Department of Pathology, Riyadh Military Hospital, P O Box 2925 59, Riyadh, 11461, Saudi Arabia
    Dig Dis Sci 56:1222-8. 2011
    ..Hepatic steatosis in hepatitis C virus (HCV)-infected patients has been shown to enhance the progression of liver fibrosis and decrease the response to antiviral therapy...
  7. ncbi Single nucleotide polymorphisms in CXCR1 gene and its association with hepatitis B infected patients in Saudi Arabia
    Fahad N Almajhdi
    Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia
    Ann Hepatol 12:220-7. 2013
    ..This study aims to investigate whether the SNPs of CXCR1 gene, could predict the likelihood of viral persistence and/or disease progression...
  8. doi Relationship of interferon-γ-inducible protein-10 kDa with viral response in patients with various heterogeneities of hepatitis C virus genotype-4
    Hamad I Al-Ashgar
    Section of Gastroenterology, Department of Medicine, King Faisal Specialist Hospital and Research Centre KFSH and RC, Riyadh 11211, Saudi Arabia
    Eur J Gastroenterol Hepatol 25:404-10. 2013
    ..We aimed to study the impact of pretreatment IP-10 levels on the sustained viral response (SVR) in HCV-4 patients (n=64) undergoing peginterferon α-2a/ribavirin therapy...
  9. doi Genetic variation at -1878 (rs2596542) in MICA gene region is associated with chronic hepatitis B virus infection in Saudi Arabian patients
    Ahmed A Al-Qahtani
    Department of Infection and Immunity, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia Liver Disease Research Center, King Saud University, Riyadh, Saudi Arabia Electronic address
    Exp Mol Pathol 95:255-8. 2013
    ..However, no significant association was observed in the case of HBV-related cirrhosis or HCC. These findings indicate that the MICA rs2596542 has a significant role in HBV infection...
  10. ncbi Predictors of significant fibrosis in chronic hepatitis B patients with low viremia
    Ayman A Abdo
    College of Medicine, Liver Disease Research Center, King Saud University Department of Medicine, Liver Unit, Division of Gastroenterology and Hepatology, University of Calgary, AB, Canada Department of Gastroenterology, Riyadh Military Hospital, Riyadh Department of Medicine, Division of Gastroenterology, King Fahad General Hospital, Jeddah Department of Medicine, Division of Gastroenterology Department of Pathology, King Faisal Specialist Hospital and Research Center Departments of Pathology Hepatobiliary Sciences and Liver Transplantation, King Abdulaziz Medical City, Riyadh, Saudi Arabia
    J Clin Gastroenterol 48:e50-6. 2014
    ..We aimed to assess both the prevalence predictors of ≥F2 fibrosis in hepatitis B envelope antigen-negative patients with HBV DNA <20,000 IU/mL...
  11. doi Safety and efficacy of peginterferon-α2a plus ribavirin treatment in renal transplant recipients with chronic hepatitis C
    Faisal M Sanai
    Department of Gastroenterology, Riyadh Military Hospital, Riyadh, Saudi Arabia
    J Hepatol 58:1096-103. 2013
    ..We assessed the safety and efficacy of PegIFNα-2a and ribavirin (RBV) combination therapy in HCV-infected RT recipients...
  12. ncbi Genetic variation in interleukin 28B and correlation with chronic hepatitis B virus infection in Saudi Arabian patients
    Ahmed A Al-Qahtani
    Department of Infection and Immunity, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia Liver Disease Research Center, King Saud University, Riyadh, Saudi Arabia
    Liver Int 34:e208-16. 2014
    ..This study was conducted to examine the role of genetic variations in IL28B on disease progression in Saudi Arabian patients chronically infected with hepatitis B virus (HBV)...
  13. ncbi Genome-wide association study of chronic hepatitis B virus infection reveals a novel candidate risk allele on 11q22.3
    Ahmed Al-Qahtani
    Department of Infection and Immunity, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    J Med Genet 50:725-32. 2013
    ..Thus, we conducted this study to investigate the genetic risk of developing active liver disease among chronic carriers of HBV...
  14. doi The coagulopathy of liver disease: does vitamin K help?
    Maha F Saja
    The Coagulation Research Laboratory, Department of Physiology, College of Medicine, King Saud University, Riyadh, Saudi Arabia
    Blood Coagul Fibrinolysis 24:10-7. 2013
    ..Vitamin K therapy does not cause significant improvements in the majority of coagulation parameters and hence does not seem to be routinely indicated in patients with liver disease...
  15. pmc Correlation between hepatitis B surface antigen titers and HBV DNA levels
    Amal Alghamdi
    Department of Medicine, College of Medicine Liver Disease Research Center, King Saud University, Riyadh 11461, Saudi Arabia
    Saudi J Gastroenterol 19:252-7. 2013
    ..To assess the correlation between serum HBsAg titers and hepatitis B virus (HBV) DNA levels in patients with hepatitis B envelop antigen-negative (HBeAg -ve) HBV genotype-D (HBV/D) infection...
  16. pmc Association between HLA variations and chronic hepatitis B virus infection in Saudi Arabian patients
    Ahmed A Al-Qahtani
    Department of Infection and Immunity, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia Liver Disease Research Center, King Saud University, Riyadh, Saudi Arabia
    PLoS ONE 9:e80445. 2014
    ..In conclusion, these results suggest that variations in HLA genes could affect susceptibility to and clearance of HBV infection in Saudi Arabian patients. ..
  17. doi Updated thresholds for alanine aminotransferase do not exclude significant histological disease in chronic hepatitis C
    Faisal M Sanai
    Department of Medicine, Division of Hepatology, Riyadh Military Hospital, Riyadh, Saudi Arabia
    Liver Int 31:1039-46. 2011
    ..We assessed significant fibrosis (≥ F2, METAVIR) in patients with PNALT and persistently elevated alanine aminotransferase (PEALT)...
  18. pmc Hepatitis C genotype 4: genotypic diversity, epidemiological profile, and clinical relevance of subtypes in Saudi Arabia
    Hamad I Al Ashgar
    Department of Medicine, Section of Gastroenterology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
    Saudi J Gastroenterol 19:28-33. 2013
    ..The aim of this study was to analyze (i) the variability of the HCV-4 subtypes, the route and source of HCV transmission and (ii) the influence of HCV-4 subtypes on their therapeutic response...
  19. doi Accuracy of international guidelines for identifying significant fibrosis in hepatitis B e antigen--negative patients with chronic hepatitis
    Faisal M Sanai
    Department of Hepatobiliary Sciences and Liver Transplantation, King Abdulaziz Medical City, Riyadh, Saudi Arabia Liver Disease Research Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia Electronic address
    Clin Gastroenterol Hepatol 11:1493-1499.e2. 2013
    ..These guidelines advocate therapy for patients with significant fibrosis (METAVIR score ≥F2); we assessed the accuracy of these guideline-defined thresholds in identifying patients with ≥F2 fibrosis...
  20. pmc Role of single nucleotide polymorphisms of KIF1B gene in HBV-associated viral hepatitis
    Ahmed Al-Qahtani
    Department of Infection and Immunity, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    PLoS ONE 7:e45128. 2012
    ..This study aims to investigate the significance of KIF1B genetic variations in HBV-associated hepatitis in patients of Saudi Arabian ethnicity...
  21. pmc Coincidence of acute brucella hepatitis and dengue fever or serologic cross-reactivity?
    Khalid I Bzeizi
    Division of Gastroenterology and Hepatology, Department of Medicine, Riyadh Military Hospital, Riyadh, Saudi Arabia
    Saudi J Gastroenterol 16:299-301. 2010
    ..We discuss, herein, the hepatic involvement of these two infections and discuss the possible serological cross-reactivity between brucella and dengue fever virus...
  22. doi Natural anticoagulants can be useful predictors of severity in chronic liver disease
    Ayman A Abdo
    Gastroenterology Unit, Department of Medicine, King Saud University, Saudi Arabia
    Blood Coagul Fibrinolysis 21:122-7. 2010
    ..Both PS and PC are sensitive markers of liver disease, but PS is a sensitive marker of liver inflammation, whereas PC may be a more sensitive marker for liver fibrosis...
  23. pmc Effect of interferon treatment on hearing of patients with chronic hepatitis C
    Abdulrahman Hagr
    Department of ENT, College of Medicine, King Saud University, Riyadh, Saudi Arabia
    Saudi J Gastroenterol 17:114-8. 2011
    ..Some reports in the literature have linked interferon therapy for the treatment of hepatitis C (HCV) with hearing loss. The aim of this study has been to examine the effects of interferon therapy on hearing of patients treated for HCV...
  24. ncbi Saudi guidelines for the diagnosis and management of hepatocellular carcinoma: technical review and practice guidelines
    Ayman A Abdo
    Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia
    Ann Saudi Med 32:174-99. 2012
    ..We hope that these guidelines will improve HCC patient care and enhance the multidisciplinary care needed for these patients...
  25. pmc Epidemiology of viral hepatitis in Saudi Arabia: are we off the hook?
    Ayman A Abdo
    Department of Medicine, Gastroenterology Unit, King Khalid University Hospital, College of Medicine, King Saud University, Riyadh, Saudi Arabia
    Saudi J Gastroenterol 18:349-57. 2012
    ..In this review, we aim to document the timeline of viral hepatitis epidemiology in Saudi Arabia, while summarizing the relevant published literature on the subject...
  26. ncbi New insights into gastrointestinal and hepatic granulomatous disorders
    Majid A Almadi
    Department of Medicine, Gastroenterology Division, King Khalid University Hospital, King Saud University, PO Box 231494, Riyadh 11321, Saudi Arabia
    Nat Rev Gastroenterol Hepatol 8:455-66. 2011
    ..In addition, the role of granulomas in harboring latent tuberculosis is reviewed. The effects of tumor necrosis factor antagonists and interferon-α on the development of granulomas are also discussed...
  27. doi Interferon-induced vitiligo in hepatitis C patients: a case series
    Issam Hamadah
    Dermatology Unit, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
    Int J Dermatol 49:829-33. 2010
    ..The association between Interferon (IFN) therapy and vitiligo is rarely reported in the literature, despite its common usage in hepatitis B viral infection, hepatitis C viral infection (HCV), hematological malignancies and melanoma...
  28. ncbi Hepatitis B genotypes: relation to clinical outcome in patients with chronic hepatitis B in Saudi Arabia
    Ayman A Abdo
    Gastroenterology Divison, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia
    World J Gastroenterol 12:7019-24. 2006
    ..To identify the most common hepatitis B virus (HBV) genotype in Saudi Arabia, and correlate the prevailing genotypes with the clinical outcome of patients...
  29. ncbi Saudi Gastroenterology Association guidelines for the diagnosis and management of hepatocellular carcinoma: summary of recommendations
    Ayman A Abdo
    College of Medicine, King Saud University, Riyadh, Saudi Arabia
    Ann Saudi Med 26:261-5. 2006
  30. ncbi Endoscopic management of bile duct injuries in 107 patients: experience of a Saudi referral center
    Mohamed A al-Karawi
    Department of Gastroenterology, P O Box 7897 A41, Riyadh Armed Forces Hospital, Riyadh 11159, Saudi Arabia
    Hepatogastroenterology 49:1201-7. 2002
    ..We studied the various endoscopic modalities to evaluate the efficacy of this approach...