Serdar Coskun

Summary

Affiliation: King Faisal Specialist Hospital and Research Centre
Country: Saudi Arabia

Publications

  1. pmc Gene expression profiling of granulosa cells from PCOS patients following varying doses of human chorionic gonadotropin
    Serdar Coskun
    Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    J Assist Reprod Genet 30:341-52. 2013
  2. pmc The correlation between endometrial thickness and outcome of in vitro fertilization and embryo transfer (IVF-ET) outcome
    Ahlam Al-Ghamdi
    Department of Obstetrics and Gynecology, Reproductive Medicine, King Faisal Specialist Hospital and Research Centre Riyadh, Kingdom of Saudi Arabia
    Reprod Biol Endocrinol 6:37. 2008
  3. doi request reprint Poor prognosis in cycles following "genuine" empty follicle syndrome
    Serdar Coskun
    Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    Eur J Obstet Gynecol Reprod Biol 150:157-9. 2010
  4. ncbi request reprint Flow cytometric ploidy analysis of testicular biopsies from sperm-negative wet preparations
    Serdar Coskun
    Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    Hum Reprod 17:977-83. 2002
  5. ncbi request reprint Nucleolar precursor body distribution in pronuclei is correlated to chromosomal abnormalities in embryos
    Serdar Coskun
    Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Centre, PO Box 3354, MBC 10, Riyadh, 11211, Saudi Arabia
    Reprod Biomed Online 7:86-90. 2003
  6. doi request reprint Preimplantation genetic diagnosis of Morquio disease
    Wafa Qubbaj
    Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    Prenat Diagn 28:900-3. 2008
  7. doi request reprint Genome-wide gene expression profiling and mutation analysis of Saudi patients with Canavan disease
    Namik Kaya
    Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Kingdom of Saudi Arabia
    Genet Med 10:675-84. 2008
  8. ncbi request reprint Outcome of in-vitro fertilization treatment and DDT levels in serum and follicular fluid
    Iman Al-Saleh
    Biological and Medical Research Department, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
    Med Sci Monit 15:BR320-33. 2009
  9. ncbi request reprint Preimplantation genetic diagnosis for Niemann-Pick disease type B
    Ali Hellani
    King Faisal Specialist Hospital and Research Center, PO Box 3354, MBC 10, Riyadh 11211, Saudi Arabia
    Prenat Diagn 24:943-8. 2004
  10. ncbi request reprint Y chromosome microdeletions: are they implicated in teratozoospermia?
    Ali Hellani
    Department of Pathology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    Hum Reprod 20:3505-9. 2005

Collaborators

Detail Information

Publications27

  1. pmc Gene expression profiling of granulosa cells from PCOS patients following varying doses of human chorionic gonadotropin
    Serdar Coskun
    Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    J Assist Reprod Genet 30:341-52. 2013
    ..The objective of this study is to evaluate the dose dependent differences in gene expression of granulosa cells following various doses of hCG treatment...
  2. pmc The correlation between endometrial thickness and outcome of in vitro fertilization and embryo transfer (IVF-ET) outcome
    Ahlam Al-Ghamdi
    Department of Obstetrics and Gynecology, Reproductive Medicine, King Faisal Specialist Hospital and Research Centre Riyadh, Kingdom of Saudi Arabia
    Reprod Biol Endocrinol 6:37. 2008
    ..To evaluate the relationship between endometrial thickness on day of human chorionic gonadotrophin administration (hCG) and pregnancy outcome in a large number of consecutive in vitro fertilization and embryo transfer (IVF-ET) cycles...
  3. doi request reprint Poor prognosis in cycles following "genuine" empty follicle syndrome
    Serdar Coskun
    Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    Eur J Obstet Gynecol Reprod Biol 150:157-9. 2010
    ..The aim of this study was to investigate the prognosis in future IVF cycles of patients with empty follicle syndrome (EFS)...
  4. ncbi request reprint Flow cytometric ploidy analysis of testicular biopsies from sperm-negative wet preparations
    Serdar Coskun
    Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    Hum Reprod 17:977-83. 2002
    ..The purpose of this study was to evaluate the sperm-negative wet preparation search results with flow cytometric ploidy analysis and histopathological examination...
  5. ncbi request reprint Nucleolar precursor body distribution in pronuclei is correlated to chromosomal abnormalities in embryos
    Serdar Coskun
    Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Centre, PO Box 3354, MBC 10, Riyadh, 11211, Saudi Arabia
    Reprod Biomed Online 7:86-90. 2003
    ....
  6. doi request reprint Preimplantation genetic diagnosis of Morquio disease
    Wafa Qubbaj
    Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    Prenat Diagn 28:900-3. 2008
    ..Preimplantation genetic diagnosis (PGD), an early form of prenatal diagnosis for couples at risk of transmitting inherited diseases, was applied to prevent transmission of this disease...
  7. doi request reprint Genome-wide gene expression profiling and mutation analysis of Saudi patients with Canavan disease
    Namik Kaya
    Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Kingdom of Saudi Arabia
    Genet Med 10:675-84. 2008
    ..The aims of this study were to identify the mutations associated with Canavan disease in Saudi Arabia and to identify differentially expressed genes likely to contribute to the development of this disease...
  8. ncbi request reprint Outcome of in-vitro fertilization treatment and DDT levels in serum and follicular fluid
    Iman Al-Saleh
    Biological and Medical Research Department, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
    Med Sci Monit 15:BR320-33. 2009
    ..Although p,p'-dichlorodiphenyltrichloroethane (DDT) is banned for agricultural purpose in Saudi Arabia, it is occasionally used to control vector-borne diseases in certain regions of the country...
  9. ncbi request reprint Preimplantation genetic diagnosis for Niemann-Pick disease type B
    Ali Hellani
    King Faisal Specialist Hospital and Research Center, PO Box 3354, MBC 10, Riyadh 11211, Saudi Arabia
    Prenat Diagn 24:943-8. 2004
    ..Given the difficult management of the disease, we opted for a preventive approach to the suffering families by screening the whole SMPD1 gene for mutations followed by Preimplantation Genetic Diagnosis (PGD)...
  10. ncbi request reprint Y chromosome microdeletions: are they implicated in teratozoospermia?
    Ali Hellani
    Department of Pathology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    Hum Reprod 20:3505-9. 2005
    ..Y chromosome microdeletions are known to impair spermatogenesis. Screenings for these microdeletions are performed mostly in patients with sperm count abnormalities...
  11. doi request reprint Levels of DNA adducts in the blood and follicular fluid of women undergoing in vitro fertilization treatment and its correlation with the pregnancy outcome
    Iman Al-Saleh
    Biological and Medical Research Department, King Faisal Specialist Hospital and Research Centre, Saudi Arabia
    Bull Environ Contam Toxicol 84:23-8. 2010
    ..05). Follicular fluid cotinine levels were associated with DNA adduct levels in blood and follicular fluid (p < 0.05). Evaluation of DNA damage resulting from oxidative stress could have a role in predicting IVF success rate...
  12. doi request reprint First successful application of preimplantation genetic diagnosis and haplotyping for congenital hyperinsulinism
    Wafa Qubbaj
    Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Center, 11211 Riyadh, Saudi Arabia
    Reprod Biomed Online 22:72-9. 2011
    ..Utilizing haplotyping increases the efficiency of PGD diagnosis as well as confirming the genetic diagnosis. It reveals the parental origin of each inherited chromosome...
  13. ncbi request reprint Zygote transfer on day 1 versus cleavage stage embryo transfer on day 3: a prospective randomized trial
    Kamal Jaroudi
    King Faisal Specialist Hospital and Research Center, Department of Obstetrics and Gynecology, Laboratory Medicine, Riyadh, Saudi Arabia
    Hum Reprod 19:645-8. 2004
    ..The objective of this study was to investigate whether transferring zygotes on day 1 would result in similar pregnancy rates compared to transferring cleavage stage embryos on day 3 in a prospective randomized trial...
  14. pmc Intracytoplasmic sperm injection and conventional in vitro fertilization are complementary techniques in management of unexplained infertility
    Kamal Jaroudi
    Department of Obstetrics and Gynecology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    J Assist Reprod Genet 20:377-81. 2003
    ..To evaluate the role of ICSI in unexplained infertility...
  15. ncbi request reprint The effect of caffeine consumption on the success rate of pregnancy as well various performance parameters of in-vitro fertilization treatment
    Iman Al-Saleh
    Environmental Health Section, Biological and Medical Research Department, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
    Med Sci Monit 16:CR598-605. 2010
    ..This study evaluated the effect of caffeine consumption on the success rate of pregnancy and various in vitro fertilization (IVF) performance parameters...
  16. ncbi request reprint Transcriptional profiling of granulosa cells from a patient with recurrent empty follicle syndrome
    Mehmet Sait Inan
    Department of Genetics, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
    Reprod Biomed Online 13:481-91. 2006
    ..Gene expression analyses might be a useful technique in identifying markers to follow a healthy follicular maturation and understanding the events that lead to EFS...
  17. ncbi request reprint Exposure to heavy metals (lead, cadmium and mercury) and its effect on the outcome of in-vitro fertilization treatment
    Iman Al-Saleh
    Biological and Medical Research Department, King Faisal Specialist Hospital and Research Centre, P O Box 3354, Riyadh 11211, Saudi Arabia
    Int J Hyg Environ Health 211:560-79. 2008
    ..It should be noted that skin-lightening creams and dental amalgam were important contributors to mercury exposure. Such finding is alarming and priority for further studies are, urgently, needed...
  18. ncbi request reprint Multiple displacement amplification on single cell and possible PGD applications
    Ali Hellani
    King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    Mol Hum Reprod 10:847-52. 2004
    ..Altogether, these data suggest that MDA can be used for single cell molecular karyotyping and the diagnosis of any single gene disorder in PGD...
  19. doi request reprint Array comparative genomic hybridization (aCGH) reveals the largest novel deletion in PCCA found in a Saudi family with propionic acidemia
    Namik Kaya
    Department of Genetics, King Faisal Specialist Hospital and Research Centre, Riyadh 11211, Saudi Arabia
    Eur J Med Genet 51:558-65. 2008
    ..The deletion so far is the largest gross change reported in the literature for the PCCA gene...
  20. ncbi request reprint Pregnancy after preimplantation genetic diagnosis for Sanjad-Sakati syndrome
    Ali Hellani
    King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    Prenat Diagn 24:302-6. 2004
    ..A singleton pregnancy was obtained, and amniosynthesis confirmed the presence of the heterozygous fetus. These results show for the first time, the feasibility of PGD for SSS...
  21. pmc Infertility treatment outcome in sub groups of obese population
    Khalid A Awartani
    Reproductive Medicine, Department of Obstetrics and Gynecology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
    Reprod Biol Endocrinol 7:52. 2009
    ..9 kg/m2) in IVF. Our aim was to compare the outcome of IVF or ICSI treatments in obese patients to that in morbidly obese patients...
  22. ncbi request reprint Whole genome amplification from a single cell: a new era for preimplantation genetic diagnosis
    Serdar Coskun
    Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    Prenat Diagn 27:297-302. 2007
    ..The utilization of MDA for single-cell molecular analysis is expanding at a high rate, and MDA is expected to soon become an integral part of PGD...
  23. ncbi request reprint Clinical application of multiple displacement amplification in preimplantation genetic diagnosis
    Ali Hellani
    King Faisal Specialist Hospital and Research Centre, Riyadh, 11211 KSA
    Reprod Biomed Online 10:376-80. 2005
    ..Altogether, these data show the simplicity and reliability of performing PGD in combination with HLA matching and STR analysis using MDA...
  24. ncbi request reprint Preimplantation genetic diagnosis for Zellweger syndrome
    Moeen Al-Sayed
    Department of Medical Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    Fertil Steril 87:1468.e1-3. 2007
    ..To report on the first live birth of a normal child after performance of preimplantation genetic diagnosis (PGD) for Zellweger syndrome (ZS)...
  25. ncbi request reprint Pregnancy after preimplantation genetic diagnosis for Ataxia Telangiectasia
    Ali Hellani
    King Faisal Specialist Hospital and Research Center, Department of Pathology and Laboratory Medicine, ART Section, P O Box 3354 MBC 10 Riyadh, 11211 Saudi Arabia
    Mol Hum Reprod 8:785-8. 2002
    ..A singleton pregnancy ensued and prenatal diagnosis confirmed the presence of exon 19. This report demonstrates that PGD is feasible despite advanced maternal age and poor response to follicle stimulation...
  26. ncbi request reprint Appropriate credit
    Kamal Jaroudi
    Fertil Steril 78:204-5; author reply 205. 2002
  27. ncbi request reprint Is recombinant follicle-stimulating hormone more effective in IVF poor responders than human menopausal gonadotrophins?
    Mamdoh Eskandar
    Department of Obstetrics and Gynecology, King Khalid University, Abha, Saudi Arabia
    Med Sci Monit 10:PI6-9. 2004
    ..The objective of this study was to determine if the recombinant human follicle-stimulating hormone (rFSH) is more effective than human menopausal gonadotrophin (hMG) in IVF poor responders...