Abderrezak Bouchama

Summary

Affiliation: King Faisal Specialist Hospital and Research Centre
Country: Saudi Arabia

Publications

  1. ncbi request reprint Heat stroke
    Abderrezak Bouchama
    Medical and Surgical Intensive Care Unit and Comparative Medicine Department, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    N Engl J Med 346:1978-88. 2002
  2. ncbi request reprint Experimental heatstroke in baboon: analysis of the systemic inflammatory response
    Abderrezak Bouchama
    Department of Comparative Medicine, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia
    Shock 24:332-5. 2005
  3. ncbi request reprint Heatstroke: facing the threat
    Abderrezak Bouchama
    Crit Care Med 34:1272-3. 2006
  4. pmc Hsp-72, a candidate prognostic indicator of heatstroke
    Mohammed Dehbi
    Department of Comparative Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh 11211, Saudi Arabia
    Cell Stress Chaperones 15:593-603. 2010
  5. ncbi request reprint Glucocorticoids do not protect against the lethal effects of experimental heatstroke in baboons
    Abderrezak Bouchama
    Departments of Comparative Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
    Shock 27:578-83. 2007
  6. pmc Cooling and hemodynamic management in heatstroke: practical recommendations
    Abderrezak Bouchama
    Department of Comparative Medicine MBC 03, King Faisal Specialist Hospital and Research Centre, P, O, Box 3354, Riyadh 11211, Saudi Arabia
    Crit Care 11:R54. 2007
  7. ncbi request reprint Prognostic factors in heat wave related deaths: a meta-analysis
    Abderrezak Bouchama
    Department of Comparative Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    Arch Intern Med 167:2170-6. 2007
  8. doi request reprint Recombinant activated protein C attenuates endothelial injury and inhibits procoagulant microparticles release in baboon heatstroke
    Abderrezak Bouchama
    Department of Comparative Medicine MBC03, King Faisal Specialist Hospital and Research Centre, P O Box 3354, Riyadh 11211, Saudi Arabia
    Arterioscler Thromb Vasc Biol 28:1318-25. 2008
  9. doi request reprint Tissue factor/factor VIIa pathway mediates coagulation activation in induced-heat stroke in the baboon
    Abderrezak Bouchama
    King Abdullah International Medical Research Center, Riyadh, Saudi Arabia
    Crit Care Med 40:1229-36. 2012
  10. doi request reprint Microvascular injury, thrombosis, inflammation, and apoptosis in the pathogenesis of heatstroke: a study in baboon model
    George T Roberts
    Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia
    Arterioscler Thromb Vasc Biol 28:1130-6. 2008

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Heat stroke
    Abderrezak Bouchama
    Medical and Surgical Intensive Care Unit and Comparative Medicine Department, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    N Engl J Med 346:1978-88. 2002
  2. ncbi request reprint Experimental heatstroke in baboon: analysis of the systemic inflammatory response
    Abderrezak Bouchama
    Department of Comparative Medicine, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia
    Shock 24:332-5. 2005
    ..Further definition of this ambivalent response is needed before identification of target of successful modulation may become possible...
  3. ncbi request reprint Heatstroke: facing the threat
    Abderrezak Bouchama
    Crit Care Med 34:1272-3. 2006
  4. pmc Hsp-72, a candidate prognostic indicator of heatstroke
    Mohammed Dehbi
    Department of Comparative Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh 11211, Saudi Arabia
    Cell Stress Chaperones 15:593-603. 2010
    ..They also suggest that extracellular Hsp-72 is a marker of multiple organs tissue damage. Whether extracellular Hsp-72 plays a role in the host immune response to heat stress merits further studies...
  5. ncbi request reprint Glucocorticoids do not protect against the lethal effects of experimental heatstroke in baboons
    Abderrezak Bouchama
    Departments of Comparative Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
    Shock 27:578-83. 2007
    ..These results do not support clinical testing of corticosteroids as beneficial in preventive or therapeutic strategies for the treatment of heatstroke in humans...
  6. pmc Cooling and hemodynamic management in heatstroke: practical recommendations
    Abderrezak Bouchama
    Department of Comparative Medicine MBC 03, King Faisal Specialist Hospital and Research Centre, P, O, Box 3354, Riyadh 11211, Saudi Arabia
    Crit Care 11:R54. 2007
    ....
  7. ncbi request reprint Prognostic factors in heat wave related deaths: a meta-analysis
    Abderrezak Bouchama
    Department of Comparative Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    Arch Intern Med 167:2170-6. 2007
    ..We conducted a meta-analysis of observational studies on risk and protective factors in heat wave-related deaths...
  8. doi request reprint Recombinant activated protein C attenuates endothelial injury and inhibits procoagulant microparticles release in baboon heatstroke
    Abderrezak Bouchama
    Department of Comparative Medicine MBC03, King Faisal Specialist Hospital and Research Centre, P O Box 3354, Riyadh 11211, Saudi Arabia
    Arterioscler Thromb Vasc Biol 28:1318-25. 2008
    ..We tested the hypothesis that the antithrombotic and cytoprotective effects of recombinant human activated protein C (rhAPC) protect baboons against the lethal effects of heatstroke...
  9. doi request reprint Tissue factor/factor VIIa pathway mediates coagulation activation in induced-heat stroke in the baboon
    Abderrezak Bouchama
    King Abdullah International Medical Research Center, Riyadh, Saudi Arabia
    Crit Care Med 40:1229-36. 2012
    ..We also examined whether coagulation inhibition influences heat stroke-induced fibrinolytic and inflammatory responses...
  10. doi request reprint Microvascular injury, thrombosis, inflammation, and apoptosis in the pathogenesis of heatstroke: a study in baboon model
    George T Roberts
    Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia
    Arterioscler Thromb Vasc Biol 28:1130-6. 2008
    ..Severe heatstroke is a leading cause of morbidity and mortality during heat waves. The pathogenesis of tissue injury, organ failure, and death in heatstroke is not well understood...
  11. pmc Toll-like receptor 4 and high-mobility group box 1 are critical mediators of tissue injury and survival in a mouse model for heatstroke
    Mohammed Dehbi
    Department of Comparative Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Kingdom of Saudi Arabia
    PLoS ONE 7:e44100. 2012
    ..They also suggest that HMGB1 is an early mediator of inflammation, tissue injury and lethality in heatstroke in the presence of defective TLR4 signaling...
  12. pmc sRAGE in diabetic and non-diabetic critically ill patients: effects of intensive insulin therapy
    Yaseen M Arabi
    College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh 11426, Saudi Arabia
    Crit Care 15:R203. 2011
    ..RAGE expression is regulated by multiple ligands, including high mobility group box-1 (HMGB-1), and is reflected by its released soluble form (sRAGE)...