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Species | Ali A AlshatwiSummaryAffiliation: King Saud University Country: Saudi Arabia Publications
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Publications
Aluminium oxide nanoparticles induce mitochondrial-mediated oxidative stress and alter the expression of antioxidant enzymes in human mesenchymal stem cellsAli A Alshatwi
Nanobiotechnology and Molecular Biology Research Lab, Department of Food Science and Nutrition, College of Food and Agricultural Sciences, Riyadh, Saudi Arabia
Food Addit Contam Part A Chem Anal Control Expo Risk Assess 30:1-10. 2013..The results of this study clearly demonstrate the nanotoxicological effects of ANPs on hMSCs, which will be useful for nanotoxicological indexing...- Al(2)O(3) nanoparticles induce mitochondria-mediated cell death and upregulate the expression of signaling genes in human mesenchymal stem cellsAli A Alshatwi
Nanobiotechnology and Molecular Biology Research Lab, Department of Food Science and Nutrition, College of Food and Agricultural Sciences, King Saud University, Riyadh 11451, Saudi Arabia
J Biochem Mol Toxicol 26:469-76. 2012..Although they provide great advantages in food and agricultural products, the chronic and acute toxicity of ANPs still needs to be assessed carefully... - Tomato powder is more protective than lycopene supplement against lipid peroxidation in ratsAli A Alshatwi
Department of Food Science and Nutrition, King Saud University, Riyadh, Saudi Arabia
Nutr Res 30:66-73. 2010..Thus, TP appeared to be more protective because of its additional ability to prevent the H(2)O(2)-induced rise in serum MDA and seemed to lower liver triglycerides more than LB treatment... - Black and green tea improves lipid profile and lipid peroxidation parameters in Wistar rats fed a high-cholesterol dietAli A Alshatwi
Department of Food and Nutrition Science, College of Food and Agricultural Sciences, King Saud University, P O Box 2460, Riyadh 11451, Saudi Arabia
J Physiol Biochem 67:95-104. 2011..These results suggest that supplementation of BT and GT may protect against the serum and hepatic abnormalities in hypercholesterolemic rats... 
Methanolic extract of Nigella sativa seed inhibits SiHa human cervical cancer cell proliferation through apoptosisTarique N Hasan
Molecular Cancer Biology Research Lab, Dept of Food Science and Nutrition, College of Food and Agricultural Sciences, King Saud University, Saudi Arabia
Nat Prod Commun 8:213-6. 2013..Thus, NS was concluded to induce apoptosis in SiHa cell through both p53 and caspases activation. NS could potentially be an alternative source of medicine for cervical cancer therapy...- A single-nucleotide polymorphism in the TP53 and MDM-2 gene modifies breast cancer risk in an ethnic Arab populationAli A Alshatwi
Molecular Cancer Biology Research Lab MCBRL, Depatment of Food Science and Nutrition, King Saud University, 11451 Riyadh, Saudi Arabia
Fundam Clin Pharmacol 26:438-43. 2012..71, 95% CI = 3.49-17.54). These findings suggest that polymorphisms of MDM2 and TP53 genes may be a genetic modifier for developing breast cancer in this ethnic population in the Arab world... - Fenugreek, a naturally occurring edible spice, kills MCF-7 human breast cancer cells via an apoptotic pathwayKholoud K Khoja
Dept of Food Sciences and Nutrition, King Saud University, Riyadh, Saudi Arabia
Asian Pac J Cancer Prev 12:3299-304. 2011..In summary, the induction of apoptosis by FCE is effected by its ability to increase the expression of pro-apoptotic genes and the spice holds promise for consideration in complementary therapy for breast cancer patients... 
Differential expression profile and genetic variants of microRNAs sequences in breast cancer patientsAli A Alshatwi
Molecular Cancer Biology Research Lab MCBRL, Department of Food Sciences and Nutrition, College of Food and Agricultural Sciences, King Saud University, Riyadh, Saudi Arabia
PLoS ONE 7:e30049. 2012..In summary, the study demonstrates that peripheral blood miRNAs and their expression and genotypic profiles can be developed as biomarkers for early diagnosis and prognosis of breast cancer...- Validation of the Antiproliferative Effects of Organic Extracts from the Green Husk of Juglans regia L. on PC-3 Human Prostate Cancer Cells by Assessment of Apoptosis-Related GenesAli A Alshatwi
Molecular Cancer Biology Research Laboratory MCBRL, Department of Food Science and Nutrition, College of Food and Agricultural Sciences, King Saud University, P O Box 2460, Riyadh 11451, Saudi Arabia
Evid Based Complement Alternat Med 2012:103026. 2012..Our data suggest the presence of bioactive compound(s) in walnut green husks that are capable of killing prostate carcinoma cells by inducing apoptosis and that the husks are a candidate source of anticancer drugs... - Single nucleotide polymorphisms in the p21 and bcl2 cancer susceptibility genes and breast cancer risk in Saudi ArabiaAli A Alshatwi
Molecular Cancer Biology Research Lab, Dept of Food Science and Nutrition, College of Food and Agricultural Sciences, King Saud University, Saudi Arabia
Asian Pac J Cancer Prev 12:2607-10. 2011..68) in patients than in healthy women. AA vs. AG+GG genotype [OR=3.56 (1.24-10.68); P=0.008] was the dominant genotype. It is likely that these genes conferring measurably increased risks of breast cancer in our study population... - CYP1A and POR gene mediated mitochondrial membrane damage induced by carbon nanoparticle in human mesenchymal stem cellsAli A Alshatwi
Nanobiotechnology and Molecular Biology Research Lab, Dept of Food Science and Nutrition, College of Food and Agriculture Sciences, King Saud University, Riyadh, Saudi Arabia Electronic address
Environ Toxicol Pharmacol 36:215-22. 2013..In conclusion, routine and high exposure of CNPs to hMSCs increased oxidative stress and mitochondrial membrane damage... - Aloe-emodin inhibits adipocyte differentiation and maturation during in vitro human mesenchymal stem cell adipogenesisPandurangan Subash-Babu
Molecular Biology Research Lab, Department of Food and Nutrition, College of Food and Agricultural Sciences, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia
J Biochem Mol Toxicol 26:291-300. 2012..AE significantly inhibited hMSCs proliferation and preadipocyte differentiation within the first 2 days of treatment, indicating that the antiadipogenic effect... - Apoptosis-mediated inhibition of human breast cancer cell proliferation by lemon citrus extractAli A Alshatwi
Molecular Cancer Biology Research Lab, Department of Food Sciences and Nutrition, College of Food and Agricultural Sciences, King Saud University, Riyadh, Saudi Arabia
Asian Pac J Cancer Prev 12:1555-9. 2011..This study provides experimental data that are relevant to the possible future clinical use of LE to treat breast cancer... - Naringin induces death receptor and mitochondria-mediated apoptosis in human cervical cancer (SiHa) cellsE Ramesh
Department of Food Science and Nutrition, King Saud University, Riyadh 11451, Saudi Arabia
Food Chem Toxicol 51:97-105. 2013..These results suggest that the induction of apoptosis by naringin is through both death-receptor and mitochondrial pathways. Taken together, our results suggest that naringin might be an effective agent to treat human cervical cancer... - Identification of functional SNPs in BARD1 gene and in silico analysis of damaging SNPs: based on data procured from dbSNP databaseAli A Alshatwi
Molecular Cancer Biology Research Laboratory, Department of Food Science and Nutrition, King Saud University, Riyadh, Saudi Arabia
PLoS ONE 7:e43939. 2012..To the best of our knowledge, until now there has been no such study on record for the BARD1 gene. Therefore, this study was undertaken to find the functional nsSNPs in BARD1... - Catechin hydrate inhibits proliferation and mediates apoptosis of SiHa human cervical cancer cellsAmal A Al-Hazzani
Dept of Botany and Microbiology, King Saud University, Saudi Arabia
Food Chem Toxicol 49:3281-6. 2011..Further study may increase our understanding of the mechanism by which CH has an effect on cervical cancer therapy...