- Effect of Curcuma longa on CYP2D6- and CYP3A4-mediated metabolism of dextromethorphan in human liver microsomes and healthy human subjectsFahad Ibrahim Al-Jenoobi
Department of Pharmaceutics, College of Pharmacy, King Saud University, PO Box 2457, Riyadh, 11451, Kingdom of Saudi Arabia
Eur J Drug Metab Pharmacokinet 40:61-6. 2015..Present findings suggested that curcuma significantly inhibits the activity of CYP2D6 in in vitro as well as in vivo; which indicates that curcuma has potential to interact with CYP2D6 substrates...
- Effect of black seed on dextromethorphan O- and N-demethylation in human liver microsomes and healthy human subjectsF I al-Jenoobi
Departments of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia
Drug Metab Lett 4:51-5. 2010..To investigate the effects of black seed on the metabolic activities of CYP3A4 and CYP2D6 in human liver microsomes and in human subjects using dextromethorphan as a probe drug...
- Effects of Nigella sativa and Lepidium sativum on cyclosporine pharmacokineticsF I al-Jenoobi
Department of Pharmaceutics, College of Pharmacy, King Saud University Riyadh, P O Box 2457, Riyadh 11451, Saudi Arabia
Biomed Res Int 2013:953520. 2013..Our findings suggest that concurrent consumption of Nigella sativa and Lepidium sativum could alter the pharmacokinetics of cyclosporine at various levels...