Ayman A Abdo

Summary

Affiliation: King Saud University
Country: Saudi Arabia

Publications

  1. pmc Genetic variability of the core protein in hepatitis C virus genotype 4 in Saudi Arabian patients and its implication on pegylated interferon and ribavirin therapy
    Fatimah S Alhamlan
    Department of Infection and Immunity, King Faisal Specialist Hospital and Research Center MBC 03, P, O, Box 3354, Riyadh 11211, Saudi Arabia
    J Transl Med 12:91. 2014
  2. pmc Patient safety culture in a large teaching hospital in Riyadh: baseline assessment, comparative analysis and opportunities for improvement
    Fadi El-Jardali
    Department of Health Management and Policy, Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon
    BMC Health Serv Res 14:122. 2014
  3. pmc Recurrence of hepatitis C virus genotype-4 infection following orthotopic liver transplantation: natural history and predictors of outcome
    Hatim Mudawi
    Department of Liver Transplatation, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
    Ann Saudi Med 29:91-7. 2009
  4. pmc Hepatitis C and poor quality of life: is it the virus or the patient?
    Ayman A Abdo
    Division of Gastroenterology, Department of Medicine, King Saud University, Riyadh, Saudi Arabia
    Saudi J Gastroenterol 14:109-13. 2008
  5. ncbi request reprint Health-related quality of life of Saudi hepatitis B and C patients
    Ayman A Abdo
    College of Medicine, King Saud University, Riyadh, Saudi Arabia
    Ann Saudi Med 32:397-403. 2012
  6. ncbi request reprint Saudi guidelines for the diagnosis and management of hepatocellular carcinoma: technical review and practice guidelines
    Ayman A Abdo
    Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia
    Ann Saudi Med 32:174-99. 2012
  7. ncbi request reprint Validation of three noninvasive laboratory variables to predict significant fibrosis and cirrhosis in patients with chronic hepatitis C in Saudi Arabia
    Ayman A Abdo
    Abdo College of Medicine, King Saud University P O Bob 2925 59 Riyadh 11461, Saudi Arabia
    Ann Saudi Med 27:89-93. 2007
  8. doi request reprint Natural anticoagulants can be useful predictors of severity in chronic liver disease
    Ayman A Abdo
    Gastroenterology Unit, Department of Medicine, King Saud University, Saudi Arabia
    Blood Coagul Fibrinolysis 21:122-7. 2010
  9. ncbi request reprint Single nucleotide polymorphisms in CXCR1 gene and its association with hepatitis B infected patients in Saudi Arabia
    Fahad N Almajhdi
    Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia
    Ann Hepatol 12:220-7. 2013
  10. doi request reprint Prevalence and impact of hepatic steatosis on the response to antiviral therapy in Saudi patients with genotypes 1 and 4 chronic hepatitis C
    Abdallah M Alqaraawi
    Department of Medicine, College of Medicine, King Saud University, and Department of Pathology, Riyadh Military Hospital, P O Box 2925 59, Riyadh, 11461, Saudi Arabia
    Dig Dis Sci 56:1222-8. 2011

Collaborators

Detail Information

Publications39

  1. pmc Genetic variability of the core protein in hepatitis C virus genotype 4 in Saudi Arabian patients and its implication on pegylated interferon and ribavirin therapy
    Fatimah S Alhamlan
    Department of Infection and Immunity, King Faisal Specialist Hospital and Research Center MBC 03, P, O, Box 3354, Riyadh 11211, Saudi Arabia
    J Transl Med 12:91. 2014
    ..Previous studies have reported that the substitution of amino acids in the HCV subgenotype 1b core protein in infected patients is associated with a poor response to pegylated interferon and ribavirin (PEG-IFN/RBV) combined therapy...
  2. pmc Patient safety culture in a large teaching hospital in Riyadh: baseline assessment, comparative analysis and opportunities for improvement
    Fadi El-Jardali
    Department of Health Management and Policy, Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon
    BMC Health Serv Res 14:122. 2014
    ..This study also aims to explore the association between patient safety culture predictors and outcomes, considering respondent characteristics and facility size...
  3. pmc Recurrence of hepatitis C virus genotype-4 infection following orthotopic liver transplantation: natural history and predictors of outcome
    Hatim Mudawi
    Department of Liver Transplatation, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
    Ann Saudi Med 29:91-7. 2009
    ..We also compared disease recurrence and outcomes between HCV-4 and other genotypes...
  4. pmc Hepatitis C and poor quality of life: is it the virus or the patient?
    Ayman A Abdo
    Division of Gastroenterology, Department of Medicine, King Saud University, Riyadh, Saudi Arabia
    Saudi J Gastroenterol 14:109-13. 2008
    ..The objective of this article is to review the association between HCV and impaired HRQOL due to fatigue and psychological disturbances...
  5. ncbi request reprint Health-related quality of life of Saudi hepatitis B and C patients
    Ayman A Abdo
    College of Medicine, King Saud University, Riyadh, Saudi Arabia
    Ann Saudi Med 32:397-403. 2012
    ....
  6. ncbi request reprint Saudi guidelines for the diagnosis and management of hepatocellular carcinoma: technical review and practice guidelines
    Ayman A Abdo
    Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia
    Ann Saudi Med 32:174-99. 2012
    ..We hope that these guidelines will improve HCC patient care and enhance the multidisciplinary care needed for these patients...
  7. ncbi request reprint Validation of three noninvasive laboratory variables to predict significant fibrosis and cirrhosis in patients with chronic hepatitis C in Saudi Arabia
    Ayman A Abdo
    Abdo College of Medicine, King Saud University P O Bob 2925 59 Riyadh 11461, Saudi Arabia
    Ann Saudi Med 27:89-93. 2007
    ....
  8. doi request reprint Natural anticoagulants can be useful predictors of severity in chronic liver disease
    Ayman A Abdo
    Gastroenterology Unit, Department of Medicine, King Saud University, Saudi Arabia
    Blood Coagul Fibrinolysis 21:122-7. 2010
    ..Both PS and PC are sensitive markers of liver disease, but PS is a sensitive marker of liver inflammation, whereas PC may be a more sensitive marker for liver fibrosis...
  9. ncbi request reprint Single nucleotide polymorphisms in CXCR1 gene and its association with hepatitis B infected patients in Saudi Arabia
    Fahad N Almajhdi
    Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia
    Ann Hepatol 12:220-7. 2013
    ..This study aims to investigate whether the SNPs of CXCR1 gene, could predict the likelihood of viral persistence and/or disease progression...
  10. doi request reprint Prevalence and impact of hepatic steatosis on the response to antiviral therapy in Saudi patients with genotypes 1 and 4 chronic hepatitis C
    Abdallah M Alqaraawi
    Department of Medicine, College of Medicine, King Saud University, and Department of Pathology, Riyadh Military Hospital, P O Box 2925 59, Riyadh, 11461, Saudi Arabia
    Dig Dis Sci 56:1222-8. 2011
    ..Hepatic steatosis in hepatitis C virus (HCV)-infected patients has been shown to enhance the progression of liver fibrosis and decrease the response to antiviral therapy...
  11. doi request reprint Is serum alanine transaminase level a reliable marker of histological disease in chronic hepatitis C infection?
    Faisal M Sanai
    Department of Medicine, Division of Gastroenterology and Hepatology, Riyadh Military Hospital, Riyadh, Saudi Arabia
    Liver Int 28:1011-8. 2008
    ..These patients are described to have a mild degree of histological liver damage. We aimed to assess the histological liver changes in HCV patients with PNALT...
  12. doi request reprint The natural history and long-term outcomes in patients with chronic hepatitis C genotype 4 after interferon-based therapy
    Faleh Z Alfaleh
    Gastroenterology Unit, Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia
    Liver Int 33:871-83. 2013
    ..Hepatitis C virus (HCV) genotype 4 (G4) infection is common in the Middle East. Post-treatment long-term outcomes have not been reported in these patients. This study evaluates these outcomes in patients after interferon-based therapy...
  13. pmc Correlation between genetic variations and serum level of interleukin 28B with virus genotypes and disease progression in chronic hepatitis C virus infection
    Ahmed Al-Qahtani
    Department of Infection and Immunity, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia Liver Disease Research Center, King Saud University, Riyadh, Saudi Arabia
    J Immunol Res 2015:768470. 2015
    ..This study indicates that variation at SNP rs8099917 could predict the serum levels of IL28B in HCV-infected patients. Furthermore, IL28B serum level may serve as a useful marker for the development of HCV-associated sequelae. ..
  14. doi request reprint Predictors of significant fibrosis in chronic hepatitis B patients with low viremia
    Ayman A Abdo
    College of Medicine, Liver Disease Research Center, King Saud University Department of Medicine, Liver Unit, Division of Gastroenterology and Hepatology, University of Calgary, AB, Canada Department of Gastroenterology, Riyadh Military Hospital, Riyadh Department of Medicine, Division of Gastroenterology, King Fahad General Hospital, Jeddah Department of Medicine, Division of Gastroenterology Department of Pathology, King Faisal Specialist Hospital and Research Center Departments of Pathology Hepatobiliary Sciences and Liver Transplantation, King Abdulaziz Medical City, Riyadh, Saudi Arabia
    J Clin Gastroenterol 48:e50-6. 2014
    ..We aimed to assess both the prevalence predictors of ≥F2 fibrosis in hepatitis B envelope antigen-negative patients with HBV DNA <20,000 IU/mL...
  15. doi request reprint Genetic variation at -1878 (rs2596542) in MICA gene region is associated with chronic hepatitis B virus infection in Saudi Arabian patients
    Ahmed A Al-Qahtani
    Department of Infection and Immunity, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia Liver Disease Research Center, King Saud University, Riyadh, Saudi Arabia Electronic address
    Exp Mol Pathol 95:255-8. 2013
    ..However, no significant association was observed in the case of HBV-related cirrhosis or HCC. These findings indicate that the MICA rs2596542 has a significant role in HBV infection...
  16. pmc Six Minute Walk Test to assess functional capacity in chronic liver disease patients
    Hatem F Alameri
    Unit of Pulmonary Medicine, Department of Medicine 38, King Saud University, PO Box 2925, Riyadh 11461, Saudi Arabia
    World J Gastroenterol 13:3996-4001. 2007
    ..To examine the utility of Six Minute Walk Test (6MWT) in patients with chronic liver disease (CLD)...
  17. doi request reprint Genetic variation in interleukin 28B and correlation with chronic hepatitis B virus infection in Saudi Arabian patients
    Ahmed A Al-Qahtani
    Department of Infection and Immunity, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia Liver Disease Research Center, King Saud University, Riyadh, Saudi Arabia
    Liver Int 34:e208-16. 2014
    ..This study was conducted to examine the role of genetic variations in IL28B on disease progression in Saudi Arabian patients chronically infected with hepatitis B virus (HBV)...
  18. doi request reprint Genome-wide association study of chronic hepatitis B virus infection reveals a novel candidate risk allele on 11q22.3
    Ahmed Al-Qahtani
    Department of Infection and Immunity, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    J Med Genet 50:725-32. 2013
    ..Thus, we conducted this study to investigate the genetic risk of developing active liver disease among chronic carriers of HBV...
  19. doi request reprint The coagulopathy of liver disease: does vitamin K help?
    Maha F Saja
    The Coagulation Research Laboratory, Department of Physiology, College of Medicine, King Saud University, Riyadh, Saudi Arabia
    Blood Coagul Fibrinolysis 24:10-7. 2013
    ..Vitamin K therapy does not cause significant improvements in the majority of coagulation parameters and hence does not seem to be routinely indicated in patients with liver disease...
  20. pmc The association of toll-like receptor 4 polymorphism with hepatitis C virus infection in Saudi Arabian patients
    Ahmed A Al-Qahtani
    Department of Infection and Immunity, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia Department of Microbiology and Immunology, Alfaisal University School of Medicine, Riyadh, Saudi Arabia Liver Disease Research Center, King Saud University, Riyadh, Saudi Arabia
    Biomed Res Int 2014:357062. 2014
    ..7% and P = 0.04). Both TLR4 SNPs under investigation were found to be significantly implicated with HCV-infection among Saudi Arabian population...
  21. pmc Correlation between hepatitis B surface antigen titers and HBV DNA levels
    Amal Alghamdi
    Department of Medicine, College of Medicine Liver Disease Research Center, King Saud University, Riyadh 11461, Saudi Arabia
    Saudi J Gastroenterol 19:252-7. 2013
    ..To assess the correlation between serum HBsAg titers and hepatitis B virus (HBV) DNA levels in patients with hepatitis B envelop antigen-negative (HBeAg -ve) HBV genotype-D (HBV/D) infection...
  22. doi request reprint Updated thresholds for alanine aminotransferase do not exclude significant histological disease in chronic hepatitis C
    Faisal M Sanai
    Department of Medicine, Division of Hepatology, Riyadh Military Hospital, Riyadh, Saudi Arabia
    Liver Int 31:1039-46. 2011
    ..We assessed significant fibrosis (≥ F2, METAVIR) in patients with PNALT and persistently elevated alanine aminotransferase (PEALT)...
  23. ncbi request reprint Histological and laboratory features of patients undergoing liver biopsy at a university hospital in Central Saudi Arabia
    Ayman A Abdo
    Department of Medicine, College of Medicine, PO Box 2925 59, Riyadh 11461, Kingdom of Saudi Arabia
    Saudi Med J 27:1493-7. 2006
    ....
  24. ncbi request reprint Biochemical and radiological predictors of malignant biliary strictures
    Ibrahim A Al-Mofleh
    Gastroenterology Division, Department of Medicine 38, King Khalid University Hospital, PO Box 2925, Riyadh 11461, Kingdom of Saudi Arabia
    World J Gastroenterol 10:1504-7. 2004
    ..The aim of this study was to identify the clinical, biochemical and or radiological predictors of malignant biliary strictures...
  25. pmc Association between HLA variations and chronic hepatitis B virus infection in Saudi Arabian patients
    Ahmed A Al-Qahtani
    Department of Infection and Immunity, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia Liver Disease Research Center, King Saud University, Riyadh, Saudi Arabia
    PLoS ONE 9:e80445. 2014
    ..In conclusion, these results suggest that variations in HLA genes could affect susceptibility to and clearance of HBV infection in Saudi Arabian patients. ..
  26. pmc Hepatitis B genotypes: relation to clinical outcome in patients with chronic hepatitis B in Saudi Arabia
    Ayman A Abdo
    Gastroenterology Divison, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia
    World J Gastroenterol 12:7019-24. 2006
    ..To identify the most common hepatitis B virus (HBV) genotype in Saudi Arabia, and correlate the prevailing genotypes with the clinical outcome of patients...
  27. doi request reprint Hepatic granuloma: decreasing trend in a high-incidence area
    Faisal M Sanai
    Department of Medicine, Division of Gastroenterology and Hepatology, Riyadh Military Hospital, Riyadh, Saudi Arabia
    Liver Int 28:1402-7. 2008
    ..Hepatic granuloma (HG) has a high reported incidence in Saudi Arabia (14.6%). We aimed to identify the incidence of HG in our centres and review its presenting features and underlying aetiology...
  28. doi request reprint Long-term protection of hepatitis B vaccine 18 years after vaccination
    Faleh Alfaleh
    Department of Medicine, College of Medicine, King Saud University, P O Box 2925 59, Riyadh 11461, Saudi Arabia
    J Infect 57:404-9. 2008
    ..This is the third evaluation study of the hepatitis B virus (HBV) vaccination program, initiated in 1989 in Saudi Arabia...
  29. doi request reprint Accuracy of international guidelines for identifying significant fibrosis in hepatitis B e antigen--negative patients with chronic hepatitis
    Faisal M Sanai
    Department of Hepatobiliary Sciences and Liver Transplantation, King Abdulaziz Medical City, Riyadh, Saudi Arabia Liver Disease Research Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia Electronic address
    Clin Gastroenterol Hepatol 11:1493-1499.e2. 2013
    ..These guidelines advocate therapy for patients with significant fibrosis (METAVIR score ≥F2); we assessed the accuracy of these guideline-defined thresholds in identifying patients with ≥F2 fibrosis...
  30. pmc Role of single nucleotide polymorphisms of KIF1B gene in HBV-associated viral hepatitis
    Ahmed Al-Qahtani
    Department of Infection and Immunity, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    PLoS ONE 7:e45128. 2012
    ..This study aims to investigate the significance of KIF1B genetic variations in HBV-associated hepatitis in patients of Saudi Arabian ethnicity...
  31. pmc Changing patterns of hepatitis A prevalence within the Saudi population over the last 18 years
    Faleh Al Faleh
    Department of Medicine, College of Medicine, King Saud University, Riyadh 11461, Saudi Arabia
    World J Gastroenterol 14:7371-5. 2008
    ..To determine the seroprevalence of Hepatitis A (HAV) amongst Saudi children and compare it with previously reported prevalence data from the same population...
  32. pmc Effect of interferon treatment on hearing of patients with chronic hepatitis C
    Abdulrahman Hagr
    Department of ENT, College of Medicine, King Saud University, Riyadh, Saudi Arabia
    Saudi J Gastroenterol 17:114-8. 2011
    ..Some reports in the literature have linked interferon therapy for the treatment of hepatitis C (HCV) with hearing loss. The aim of this study has been to examine the effects of interferon therapy on hearing of patients treated for HCV...
  33. pmc Epidemiology of viral hepatitis in Saudi Arabia: are we off the hook?
    Ayman A Abdo
    Department of Medicine, Gastroenterology Unit, King Khalid University Hospital, College of Medicine, King Saud University, Riyadh, Saudi Arabia
    Saudi J Gastroenterol 18:349-57. 2012
    ..In this review, we aim to document the timeline of viral hepatitis epidemiology in Saudi Arabia, while summarizing the relevant published literature on the subject...
  34. ncbi request reprint Saudi Gastroenterology Association guidelines for the diagnosis and management of hepatocellular carcinoma: summary of recommendations
    Ayman A Abdo
    College of Medicine, King Saud University, Riyadh, Saudi Arabia
    Ann Saudi Med 26:261-5. 2006
  35. doi request reprint Interferon-induced vitiligo in hepatitis C patients: a case series
    Issam Hamadah
    Dermatology Unit, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
    Int J Dermatol 49:829-33. 2010
    ..The association between Interferon (IFN) therapy and vitiligo is rarely reported in the literature, despite its common usage in hepatitis B viral infection, hepatitis C viral infection (HCV), hematological malignancies and melanoma...
  36. doi request reprint Ginger ingredients inhibit the development of diethylnitrosoamine induced premalignant phenotype in rat chemical hepatocarcinogenesis model
    Mahmoud A Mansour
    Department of Pharmacology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia
    Biofactors 36:483-90. 2010
    ..These findings suggest a protective effect of ginger extract against premalignant stages of liver cancer in the DEN-initiated and CCl(4) -promoted hepatocarcinogenesis model in rats...
  37. doi request reprint Seroprevalence rates of Helicobacter pylori and viral hepatitis A among adolescents in three regions of the Kingdom of Saudi Arabia: is there any correlation?
    Faleh Z Al Faleh
    Department of Medicine Gastroenterology Unit, College of Medicine, Liver Disease Research Center, King Saud University, Riyadh, Saudi Arabia
    Helicobacter 15:532-7. 2010
    ..The aim of this paper was to study seroprevalence rates of H. pylori and HAV among the adolescent population in three regions of KSA and to determine whether there was any correlation between them...
  38. pmc Use of alternative medicine by Saudi liver disease patients attending a tertiary care center: prevalence and attitudes
    Abdulaziz A Al-Zahim
    College of Medicine, King Saud University, Liver Disease Research Center, Riyadh, Saudi Arabia
    Saudi J Gastroenterol 19:75-80. 2013
    ..Although liver disease is prevalent in Saudi Arabia, not much is known about CAM use among Saudi liver disease patients. Thus, this study aimed to assess the prevalence of CAM use in these patients and their attitudes toward it...