Gustavo Saposnik

Summary

Publications

  1. ncbi request reprint Recent advances in stroke outcomes research: contributions from Canada
    Gustavo Saposnik
    MD, MSc, FAHA, is the director of the Stroke Outcomes Research Unit, Division of Neurology, Department of Medicine, at St Michael s adjunct scientist, Institute for Clinical Evaluative Sciences ICES and assistant professor, Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario Dr Saposnik can be contacted at
    Healthc Q 13:20-3. 2010
  2. pmc JURaSSiC: accuracy of clinician vs risk score prediction of ischemic stroke outcomes
    Gustavo Saposnik
    Stroke Outcomes Research Unit, Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Canada
    Neurology 81:448-55. 2013
  3. doi request reprint The iScore predicts efficacy and risk of bleeding in the National Institute of Neurological disorders and Stroke Tissue Plasminogen Activator Stroke Trial
    Gustavo Saposnik
    Stroke Outcomes Research Unit, Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Canada
    J Stroke Cerebrovasc Dis 22:876-82. 2013
  4. doi request reprint Atrial fibrillation in ischemic stroke: predicting response to thrombolysis and clinical outcomes
    Gustavo Saposnik
    MSc, FAHA, FRCPC, Stroke Outcomes Research Center, Department of Medicine, St Michael s Hospital, University of Toronto, 55 Queen St E, Toronto, Ontario, M5C 1R6, Canada
    Stroke 44:99-104. 2013
  5. pmc Stroke Prognostication using Age and NIH Stroke Scale: SPAN-100
    Gustavo Saposnik
    Stroke Outcomes Research Unit, Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Canada
    Neurology 80:21-8. 2013
  6. doi request reprint Is pre-existing dementia an independent predictor of outcome after stroke? A propensity score-matched analysis
    Gustavo Saposnik
    Division of Neurology, Departments of Medicine and Health Policy, Management and Evaluation, Institute for Clinical Evaluative Sciences, St Michael s Hospital, University of Toronto, 55 Queen St East, Suite 931, Toronto, ON, M5C 1R6, Canada
    J Neurol 259:2366-75. 2012
  7. doi request reprint The iScore predicts effectiveness of thrombolytic therapy for acute ischemic stroke
    Gustavo Saposnik
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Stroke 43:1315-22. 2012
  8. doi request reprint Fabry's disease: a prospective multicenter cohort study in young adults with cryptogenic stroke
    Gustavo Saposnik
    Departments of Medicine and Health Policy, Management and Evaluation, Division of Neurology, Stroke Outcomes Research Unit, St Michael s Hospital, University of Toronto, Toronto, ON, Canada
    Int J Stroke 7:265-73. 2012
  9. doi request reprint The iScore predicts poor functional outcomes early after hospitalization for an acute ischemic stroke
    Gustavo Saposnik
    Stroke Outcomes Research Unit, Stroke Outcome Research Canada Working Group, Department of Medicine, St Michael s Hospital, University of Toronto, 55 Queen Street E, Toronto, Ontario, M5C 1R6, Canada
    Stroke 42:3421-8. 2011
  10. doi request reprint Stroke unit care: does ischemic stroke subtype matter?
    Gustavo Saposnik
    Stroke Outcomes Research Unit, Stroke Research Unit, Department of Medicine, Division of Neurology, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Int J Stroke 6:244-50. 2011

Collaborators

Detail Information

Publications52

  1. ncbi request reprint Recent advances in stroke outcomes research: contributions from Canada
    Gustavo Saposnik
    MD, MSc, FAHA, is the director of the Stroke Outcomes Research Unit, Division of Neurology, Department of Medicine, at St Michael s adjunct scientist, Institute for Clinical Evaluative Sciences ICES and assistant professor, Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario Dr Saposnik can be contacted at
    Healthc Q 13:20-3. 2010
    ..By linking the care people get to the outcomes they experience, outcomes research can become the key to developing better ways to monitor and improve the quality of care. ..
  2. pmc JURaSSiC: accuracy of clinician vs risk score prediction of ischemic stroke outcomes
    Gustavo Saposnik
    Stroke Outcomes Research Unit, Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Canada
    Neurology 81:448-55. 2013
    ..We compared the accuracy of clinicians and a risk score (iScore) to predict observed outcomes following an acute ischemic stroke...
  3. doi request reprint The iScore predicts efficacy and risk of bleeding in the National Institute of Neurological disorders and Stroke Tissue Plasminogen Activator Stroke Trial
    Gustavo Saposnik
    Stroke Outcomes Research Unit, Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Canada
    J Stroke Cerebrovasc Dis 22:876-82. 2013
    ..Further prospective studies are needed before a change in practice can be recommended...
  4. doi request reprint Atrial fibrillation in ischemic stroke: predicting response to thrombolysis and clinical outcomes
    Gustavo Saposnik
    MSc, FAHA, FRCPC, Stroke Outcomes Research Center, Department of Medicine, St Michael s Hospital, University of Toronto, 55 Queen St E, Toronto, Ontario, M5C 1R6, Canada
    Stroke 44:99-104. 2013
    ..Atrial fibrillation (AF) increases the risk of stroke and is associated with poor stroke outcomes. Limited tools are available to evaluate clinical outcomes and response to thrombolysis in stroke patients with AF...
  5. pmc Stroke Prognostication using Age and NIH Stroke Scale: SPAN-100
    Gustavo Saposnik
    Stroke Outcomes Research Unit, Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Canada
    Neurology 80:21-8. 2013
    ..We evaluated the effect of an index combining age and stroke severity on response to IV tissue plasminogen activator (tPA) among patients in the National Institute of Neurological Disorders and Stroke (NINDS) tPA stroke trials...
  6. doi request reprint Is pre-existing dementia an independent predictor of outcome after stroke? A propensity score-matched analysis
    Gustavo Saposnik
    Division of Neurology, Departments of Medicine and Health Policy, Management and Evaluation, Institute for Clinical Evaluative Sciences, St Michael s Hospital, University of Toronto, 55 Queen St East, Suite 931, Toronto, ON, M5C 1R6, Canada
    J Neurol 259:2366-75. 2012
    ..Pre-existing dementia may not necessarily preclude access to thrombolytic therapy and specialized stroke care...
  7. doi request reprint The iScore predicts effectiveness of thrombolytic therapy for acute ischemic stroke
    Gustavo Saposnik
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Stroke 43:1315-22. 2012
    ..The purpose of this study was to determine the ability of the iScore to predict clinical response and risk of hemorrhagic transformation after tPA...
  8. doi request reprint Fabry's disease: a prospective multicenter cohort study in young adults with cryptogenic stroke
    Gustavo Saposnik
    Departments of Medicine and Health Policy, Management and Evaluation, Division of Neurology, Stroke Outcomes Research Unit, St Michael s Hospital, University of Toronto, Toronto, ON, Canada
    Int J Stroke 7:265-73. 2012
    ..Limited information is available on the prevalence of Fabry's disease, a treatable multisystem inherited lysosomal storage disorder, and disability in young patients with cryptogenic stroke...
  9. doi request reprint The iScore predicts poor functional outcomes early after hospitalization for an acute ischemic stroke
    Gustavo Saposnik
    Stroke Outcomes Research Unit, Stroke Outcome Research Canada Working Group, Department of Medicine, St Michael s Hospital, University of Toronto, 55 Queen Street E, Toronto, Ontario, M5C 1R6, Canada
    Stroke 42:3421-8. 2011
    ..The iScore is a prediction tool originally developed to estimate the risk of death after hospitalization for an acute ischemic stroke. Our objective was to determine whether the iScore could also predict poor functional outcomes...
  10. doi request reprint Stroke unit care: does ischemic stroke subtype matter?
    Gustavo Saposnik
    Stroke Outcomes Research Unit, Stroke Research Unit, Department of Medicine, Division of Neurology, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Int J Stroke 6:244-50. 2011
    ..Stroke unit care improves outcomes following ischemic stroke. However, it is not known whether all ischemic stroke subtypes benefit equally from stroke unit admission...
  11. doi request reprint Virtual reality in stroke rehabilitation: a meta-analysis and implications for clinicians
    Gustavo Saposnik
    Stroke Outcomes Research Unit, Department of Medicine, 55 Queen Street East, Suite 931, St Michael s Hospital, University of Toronto, Toronto, M5C 1R6, Canada
    Stroke 42:1380-6. 2011
    ..Virtual reality (VR) technology is a novel adjunctive therapy that could be applied in neurorehabilitation. We performed a meta-analysis to determine the added benefit of VR technology on arm motor recovery after stroke...
  12. doi request reprint Care and outcomes in patients with ischemic stroke with and without preexisting dementia
    G Saposnik
    Department of Medicine, University of Toronto, Toronto M5C 1R6, Canada
    Neurology 77:1664-73. 2011
    ..To describe clinical characteristics and evaluate processes of care and outcomes at discharge in patients with ischemic stroke with and without preexisting dementia...
  13. doi request reprint Age disparities in stroke quality of care and delivery of health services
    Gustavo Saposnik
    Stroke Research Unit, Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Stroke 40:3328-35. 2009
    ..Limited information is available on the effect of age on stroke management and care delivery. Our aim was to determine whether access to stroke care, delivery of health services, and clinical outcomes after stroke are affected by age...
  14. doi request reprint Do all age groups benefit from organized inpatient stroke care?
    Gustavo Saposnik
    Stroke Research Unit, Division of Neurology, Department of Medicine, Stroke Outcome Research Canada, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Stroke 40:3321-7. 2009
    ..We sought to determine whether the reduction in mortality or institutionalization seen with organized stroke care was similar across all age groups...
  15. doi request reprint IScore: a risk score to predict death early after hospitalization for an acute ischemic stroke
    Gustavo Saposnik
    Stroke Outcomes Research Centre, Stroke Outcome Research Canada Working Group, Department of Medicine, St Michael s Hospital, University of Toronto, 55 Queen St E, Toronto, Ontario, Canada
    Circulation 123:739-49. 2011
    ..Our aim was to identify predictors of mortality and to develop and validate a risk score model using information available at hospital presentation...
  16. doi request reprint Gender differences in stroke care and outcomes in Ontario
    Moira K Kapral
    Department of Medicine, University of Toronto, Toronto General Hospital, 200 Elizabeth St, Toronto, Ontario, Canada
    Womens Health Issues 21:171-6. 2011
    ....
  17. pmc Pulmonary embolism in ischemic stroke: clinical presentation, risk factors, and outcome
    Jitphapa Pongmoragot
    Stroke Outcomes Research Center, Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, Ontario, Canada
    J Am Heart Assoc 2:e000372. 2013
    ..Limited information is available on the frequency of pulmonary embolism (PE) in patients with an acute ischemic stroke (AIS). We evaluated clinical characteristics, predisposing factors, and outcomes in AIS patients with PE...
  18. ncbi request reprint Escalating levels of access to in-hospital care and stroke mortality
    Gustavo Saposnik
    Stroke Research Unit, Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, M5C 1R6, Canada
    Stroke 39:2522-30. 2008
    ..However, limited information is available comparing different levels of organized care. Our aim was to determine whether escalating levels of organized care can improve stroke outcomes...
  19. doi request reprint Variables associated with 7-day, 30-day, and 1-year fatality after ischemic stroke
    Gustavo Saposnik
    Stroke Research Unit, Division of Neurology, Department of Medicine, Li Ka Shing Knowledge Institute, St Michael s Hospital, University of Toronto, Toronto, Canada
    Stroke 39:2318-24. 2008
    ..However, limited information is available concerning variables associated with stroke case fatality at these different points in time. We sought to identify and compare variables associated with 7-day, 30-day, and 1-year stroke fatality...
  20. ncbi request reprint Predictors of major neurologic improvement after thrombolysis in acute stroke
    Gustavo Saposnik
    Department of Clinical Neurological Sciences, London Health Science Center, The University of Western Ontario, London, Ontario, Canada
    Neurology 65:1169-74. 2005
    ..Major neurologic improvement at 24 hours after administration of recombinant tissue plasminogen activator (rt-PA) in acute stroke may predict good outcome at 3 months...
  21. doi request reprint Stroke in the very elderly: hospital care, case fatality and disposition
    Gustavo Saposnik
    Stroke Research Program, South East Toronto Regional Stroke Center, Division of Neurology, Department of Medicine, St Michael s Hospital, Ont, Canada
    Cerebrovasc Dis 27:537-43. 2009
    ..However, limited information is available about the burden of stroke in individuals over 90...
  22. doi request reprint Socioeconomic status, hospital volume, and stroke fatality in Canada
    Gustavo Saposnik
    Department of Medicine, Division of Neurology, Stroke Research Unit, South East Toronto Regional Stroke Center, St Michael sHospital, University of Toronto, Toronto, Canada
    Stroke 39:3360-6. 2008
    ..We sought to determine whether residence in a low-income neighborhood was associated with admission to low-volume facilities and whether this contributed to differences in fatality after stroke...
  23. doi request reprint Influence of socioeconomic status on distance traveled and care after stroke
    Christopher Ahuja
    Queen s University, St Michael s Hospital, Toronto, Canada
    Stroke 43:233-5. 2012
    ..Socioeconomic status may influence access to stroke care, including transportation and admission to different facility types...
  24. doi request reprint Organized outpatient care: stroke prevention clinic referrals are associated with reduced mortality after transient ischemic attack and ischemic stroke
    Fiona Webster
    Department of Surgery, University of Toronto, Toronto, Ontario, M5G 1V7, Canada
    Stroke 42:3176-82. 2011
    ..We compared 1-year mortality and stroke readmission in patients with transient ischemic attack or ischemic stroke referred versus not referred to an SPC...
  25. doi request reprint Bilateral medial medullary infarction: a systematic review
    Jitphapa Pongmoragot
    Stroke Research Unit, Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    J Stroke Cerebrovasc Dis 22:775-80. 2013
    ..Clinical presentations were mostly rostral medullary lesions. Large-artery atherosclerosis and branch disease were the most common stroke mechanisms. The clinical outcome was usually poor. ..
  26. doi request reprint Predicting clinical outcomes after thrombolysis using the iScore: results from the Virtual International Stroke Trials Archive
    Gustavo Saposnik
    From the Stroke Outcomes Research Unit, Division of Neurology, Department of Medicine, St Michael s Hospital, Institute of Health Policy, Management and Evaluation iHPME, University of Toronto, Toronto, Canada G S Departments of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI M J R Clinical and Translational Science Institute, Department of Neurology, University of California, San Francisco, CA S C J Stroke Trials Unit, Division of Stroke Medicine, University of Nottingham, Nottingham, United Kingdom P M W B Department of Neurology, Medical University of South Carolina, Charleston, SC B O and Institute for Clinical Evaluative Sciences ICES, Toronto, Canada G S
    Stroke 44:2755-9. 2013
    ..Our goal was to determine the ability of the iScore to estimate clinical outcomes after intravenous thrombolysis tissue-type plasminogen activator (tPA) in the Virtual International Stroke Trials Archive (VISTA)...
  27. doi request reprint Is stroke history reliably reported by elderly with cognitive impairment? A community-based study
    Ya Ping Jin
    Department of Clinical Neurological Sciences, London Health Sciences Centre and University of Western Ontario, London, Ontario, Canada
    Neuroepidemiology 35:215-20. 2010
    ..We tested the validity of response to a stroke questionnaire versus clinical diagnosis of stroke among elderly people with and without cognitive impairment...
  28. doi request reprint The Canadian Neurological Scale and the NIHSS: development and validation of a simple conversion model
    Yongchai Nilanont
    Division of Neurology, Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Cerebrovasc Dis 30:120-6. 2010
    ..The CNS requires less extensive neurological evaluation and is quicker and simpler to administer...
  29. doi request reprint Intracerebral hemorrhage from cerebral venous thrombosis
    Jitphapa Pongmoragot
    Stroke Outcomes Research Unit, Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, Canada
    Curr Atheroscler Rep 14:382-9. 2012
    ..Intracerebral hemorrhage in the context of CVT is usually associated with poorer outcomes compared to CVT without ICH...
  30. pmc Predicting clinical outcomes and response to thrombolysis in acute stroke patients with diabetes
    Davar Nikneshan
    Stroke Outcomes Research Centre, Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Canada
    Diabetes Care 36:2041-7. 2013
    ..We explored how the iScore (www.sorcan.ca/iscore), a validated risk score, predicts clinical outcomes in stroke patients with and without diabetes...
  31. doi request reprint Stroke outcome in those over 80: a multicenter cohort study across Canada
    Gustavo Saposnik
    South East Toronto Regional Stroke Center, Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Stroke 39:2310-7. 2008
    ..However, limited information is available about the burden of stroke in individuals over 80. We sought to evaluate differences in clinical outcomes in Canadians over 80 years old hospitalized for an acute ischemic stroke...
  32. doi request reprint Effectiveness of virtual reality using Wii gaming technology in stroke rehabilitation: a pilot randomized clinical trial and proof of principle
    Gustavo Saposnik
    Division of Neurology, Departments of Medicine and Health Policy Management and Evaluation and Institute for Clinical Evaluative Sciences, Li Ka Shing Knowledge Institute of St Michael s Hospital, Dalla Lana, School of Public Health, University of Toronto, Ontario, Canada
    Stroke 41:1477-84. 2010
    ..Although existing evidence suggests that increasing intensity of stroke rehabilitation therapy results in better motor recovery, limited evidence is available on the efficacy of virtual reality for stroke rehabilitation...
  33. doi request reprint Applying the evidence: do patients with stroke, coronary artery disease, or both achieve similar treatment goals?
    Gustavo Saposnik
    Division of Cardiology, Canadian Heart Research Centre and Terrence Donnelly Heart Centre, University of Toronto, Canada
    Stroke 40:1417-24. 2009
    ..We sought to evaluate and compare differences in treatment patterns and the attainment of current guideline-recommended targets in unselected high-risk ambulatory patients with CAD, CVD, or both...
  34. ncbi request reprint Weekends: a dangerous time for having a stroke?
    Gustavo Saposnik
    Stroke Program, Department of Clinical Neurological Sciences, London Health Sciences Center, University of Western Ontario, London, ON, Canada
    Stroke 38:1211-5. 2007
    ..However, limited information is available concerning the "weekend effect" on stroke mortality. Our aim was to evaluate the impact of weekend admissions on stroke mortality in different settings...
  35. doi request reprint Disparities in management patterns and outcomes of patients with non-ST-elevation acute coronary syndrome with and without a history of cerebrovascular disease
    Tony C Lee
    Division of Cardiology, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Am J Cardiol 105:1083-9. 2010
    ....
  36. doi request reprint Influence of seizures on stroke outcomes: a large multicenter study
    Chin Wei Huang
    From the Epilepsy Program, Department of Clinical Neurological Sciences C W H, D A S, J G B, Western University, London, Canada Department of Neurology C W H, National Cheng Kung University Hospital, School of Medicine, National Cheng Kung University, Tainan, Taiwan University of Toronto G S, St Michael s Hospital and Institute for Clinical Evaluative Sciences G S, J F, Toronto, Canada
    Neurology 82:768-76. 2014
    ....
  37. ncbi request reprint Does a birthday predispose to vascular events?
    Gustavo Saposnik
    Stroke Team, Department of Clinical Neurological Sciences, London Health Sciences Center, University of Western Ontario, Ontario, Canada
    Neurology 67:300-4. 2006
    ..To examine the influence of birthdays on the onset and course of vascular events such as stroke, TIA, and acute myocardial infarction (AMI)...
  38. doi request reprint Detection and treatment of post stroke depression: results from the registry of the Canadian stroke network
    Nathan Herrmann
    Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Int J Geriatr Psychiatry 26:1195-200. 2011
    ..Depression occurs in approximately one-third of patients following stroke based on studies that screen entire stroke populations. Less is known about the detection and treatment of post stroke depression (PSD) in routine clinical practice...
  39. doi request reprint Association between weekend hospital presentation and stroke fatality
    Jiming Fang
    Toronto General Hospital, 200 Elizabeth Street, Toronto, Ontario, Canada
    Neurology 75:1589-96. 2010
    ..Previous studies have found higher stroke case fatality in patients admitted to the hospital on weekends compared to weekdays, but the reasons for this association are not known...
  40. ncbi request reprint Prevalence of Fabry disease in stroke patients--a systematic review and meta-analysis
    Qiyun Shi
    Health and Rehabilitation Sciences, Western University, Elborn College, London, Ontario Stroke Outcomes Research Center, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto Electronic address
    J Stroke Cerebrovasc Dis 23:985-92. 2014
    ..Fabry disease is an uncommon but treatable cause of stroke. Enzyme replacement therapy helps improve neurologic symptoms. We conducted a systematic review and meta-analysis to evaluate the prevalence of Fabry disease in stroke patients...
  41. ncbi request reprint The CLOQS trial protocol: a cluster-randomized trial evaluating a simple, low-cost intervention to reduce treatment times in acute stroke
    Richard H Swartz
    Department of Medicine Neurology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Int J Stroke 9:525-8. 2014
    ..Paradoxically, the earlier a stroke patient arrives to hospital, the longer treatment takes. There is an urgent need to shift focus away from the 4.5 hour time window, towards treatment times <60 minutes...
  42. doi request reprint Prevalence of Fabry disease in young patients with cryptogenic ischemic stroke
    Véronique Dubuc
    Division of Neurology, Department of Medicine, Centre Hospitalier de l Universite de Montreal, Universite de Montreal, Montreal, Quebec, Canada
    J Stroke Cerebrovasc Dis 22:1288-92. 2013
    ..A lower prevalence was found in other geographic regions...
  43. doi request reprint Treatment and outcomes of non-ST elevation acute coronary syndromes in relation to burden of pre-existing vascular disease
    Michael Mohareb
    Terrence Donnelly Heart Centre, St Michael s Hospital, Toronto, ON, Canada University of Toronto, Toronto, ON, Canada
    Int J Cardiol 168:2720-5. 2013
    ..However, the relationships between pre-existing vascular disease and the treatment and outcome of acute coronary syndrome (ACS), have not been well characterized...
  44. ncbi request reprint Optimizing discharge planning: clinical predictors of longer stay after recombinant tissue plasminogen activator for acute stroke
    Gustavo Saposnik
    Stroke Program, Department of Clinical Neurological Sciences and Southwestern Ontario Coordinated Stroke Strategy, London Health Science Center, The University of Western Ontario, London, Ontario, Canada
    Stroke 36:147-50. 2005
    ..Although studies have identified variables associated with LOS, few have analyzed predictors of longer stay after receiving thrombolytic therapy for acute stroke...
  45. doi request reprint Pontine warning syndrome
    Gustavo Saposnik
    Stroke Research Unit, Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, 55 Queen St E, Ste 931, Toronto ONM5C1R6, Canada
    Arch Neurol 65:1375-7. 2008
    ..Little is known about stroke mechanisms in patients with fluctuating symptoms and the role of branch atherosclerotic disease...
  46. doi request reprint Homocysteine-lowering therapy and stroke risk, severity, and disability: additional findings from the HOPE 2 trial
    Gustavo Saposnik
    Department of Medicine, Division of Neurology, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Stroke 40:1365-72. 2009
    ..Our aim was to determine whether vitamin therapy reduces the risk of ischemic and hemorrhagic stroke, as well as stroke-related disability...
  47. doi request reprint Quality of acute ischemic stroke care in Thailand: a prospective multicenter countrywide cohort study
    Yongchai Nilanont
    Division of Neurology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand Electronic address
    J Stroke Cerebrovasc Dis 23:213-9. 2014
    ..Data concerning quality of acute stroke care and outcome are scarce in developing countries...
  48. doi request reprint Effect of socioeconomic status on inpatient mortality and use of postacute care after subarachnoid hemorrhage
    Blessing N R Jaja
    From the Keenan Research Centre, Li Ka Shing Knowledge Institute B N R J, G S, R N, T A S, K E T, R L M, Division of Neurology G S, Division of Neurosurgery B N R J, T A S, R L M, St Michael s Hospital, Toronto, ON, Canada Institute of Medical Science B N R J, G S, T A S, R L M, Dalla Lana School of Public Health R N, K E T, University of Toronto, Toronto, ON, Canada and Division of Neurosurgery D R, McMaster University, Hamilton, ON, Canada
    Stroke 44:2842-7. 2013
    ..This study investigated socioeconomic status-related differences in risk of inpatient mortality and use of institutional postacute care after subarachnoid hemorrhage in the United States and Canada...
  49. ncbi request reprint Roadway crash risks in recent immigrants
    Donald A Redelmeier
    Department of Medicine, University of Toronto, Canada
    Accid Anal Prev 43:2128-33. 2011
    ..These findings suggest that, contrary to popular opinion, recent immigrants are less prone to be drivers in serious motor vehicle crashes...
  50. doi request reprint Genetic testing in combination with preventive donepezil treatment for patients with amnestic mild cognitive impairment: an exploratory economic evaluation of personalized medicine
    Sandjar Djalalov
    Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, 30 Bond Street, Toronto, ON, M5B 1W8, Canada
    Mol Diagn Ther 16:389-99. 2012
    ....
  51. doi request reprint Delirium in acute stroke: a systematic review and meta-analysis
    Qiyun Shi
    Health and Rehabilitation Sciences, The University of Western Ontario, Elborn College, London, Ontario, Canada
    Stroke 43:645-9. 2012
    ..Delirium is common in the early stage after hospitalization for an acute stroke. We conducted a systematic review and meta-analysis to evaluate the outcomes of acute stroke patients with delirium...
  52. doi request reprint Pearls and oy-sters: carotid dissection with normal arterial lumen
    Jitphapa Pongmoragot
    Stroke Program, Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, Ontario, Canada
    Neurology 80:e115-7. 2013
    ..Isolated lower cranial nerve palsy in carotid dissection is uncommon...