Robert A Sandhaus

Summary

Publications

  1. ncbi request reprint Delay in diagnosis of alpha1-antitrypsin deficiency: a continuing problem
    James K Stoller
    Department of Pulmonary, Allergy, and Critical Care Medicine, Cleveland Clinic Foundation, A 90, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Chest 128:1989-94. 2005
  2. doi request reprint alpha1-Antitrypsin augmentation therapy for PI*MZ heterozygotes: a cautionary note
    Robert A Sandhaus
    National Jewish Medical and Research Center, Denver, CO, USA
    Chest 134:831-4. 2008
  3. pmc Association of IREB2 and CHRNA3 polymorphisms with airflow obstruction in severe alpha-1 antitrypsin deficiency
    Woo Jin Kim
    Channing Laboratory and the Division of Pulmonary and Critical Care Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA, USA
    Respir Res 13:16. 2012
  4. pmc alpha1-Antitrypsin deficiency . 6: new and emerging treatments for alpha1-antitrypsin deficiency
    R A Sandhaus
    Alpha 1 Program, National Jewish Medical and Research Center, Southside Building G106, 1400 Jackson Street, Denver, CO 80206, USA
    Thorax 59:904-9. 2004
  5. pmc The prospective association of perceived criticism with dyspnea in chronic lung disease
    Kristen E Holm
    National Jewish Health, Department of Medicine, Denver, CO, USA
    J Psychosom Res 74:450-3. 2013
  6. pmc The impact of age on outcomes in chronic obstructive pulmonary disease differs by relationship status
    Kristen E Holm
    Department of Medicine, National Jewish Health, 1400 Jackson Street, Denver, CO, 80206, USA
    J Behav Med 37:654-63. 2014
  7. pmc Differences in adjustment between individuals with alpha-1 antitrypsin deficiency (AATD)-associated COPD and non-AATD COPD
    Kristen E Holm
    Department of Medicine, National Jewish Health, Denver, CO 80206, USA
    COPD 10:226-34. 2013
  8. doi request reprint Neutrophil elastase-mediated lung disease
    Robert A Sandhaus
    National Jewish Health, Denver, Colorado 80206, USA
    COPD 10:60-3. 2013
  9. ncbi request reprint Alpha-1 antitrypsin deficiency: whom to test, whom to treat?
    Robert A Sandhaus
    Department of Medicine, National Jewish Health, Denver, Colorado 80206, USA
    Semin Respir Crit Care Med 31:343-7. 2010
  10. doi request reprint Biochemical efficacy and safety of a new, ready-to-use, liquid alpha-1-proteinase inhibitor, GLASSIA (alpha1-proteinase inhibitor (human), intravenous)
    Robert A Sandhaus
    1National Jewish Health, Denver, CO, USA
    COPD 11:17-25. 2014

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Delay in diagnosis of alpha1-antitrypsin deficiency: a continuing problem
    James K Stoller
    Department of Pulmonary, Allergy, and Critical Care Medicine, Cleveland Clinic Foundation, A 90, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Chest 128:1989-94. 2005
    ..We also determined whether individuals living near medical centers with an expressed interest in AAT deficiency experienced shorter diagnostic delays than those living at a distance...
  2. doi request reprint alpha1-Antitrypsin augmentation therapy for PI*MZ heterozygotes: a cautionary note
    Robert A Sandhaus
    National Jewish Medical and Research Center, Denver, CO, USA
    Chest 134:831-4. 2008
    ..This commentary discusses the treatment of AAT deficiency and the concerns regarding treatment of PI*MZ individuals. We conclude that clinicians should avoid prescribing augmentation therapy for this heterozygote population...
  3. pmc Association of IREB2 and CHRNA3 polymorphisms with airflow obstruction in severe alpha-1 antitrypsin deficiency
    Woo Jin Kim
    Channing Laboratory and the Division of Pulmonary and Critical Care Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA, USA
    Respir Res 13:16. 2012
    ..We investigated whether SNPs in the chromosome 15q region would be modifiers for lung function and COPD in AAT deficiency...
  4. pmc alpha1-Antitrypsin deficiency . 6: new and emerging treatments for alpha1-antitrypsin deficiency
    R A Sandhaus
    Alpha 1 Program, National Jewish Medical and Research Center, Southside Building G106, 1400 Jackson Street, Denver, CO 80206, USA
    Thorax 59:904-9. 2004
    ..These innovative approaches may prove effective at modifying or eliminating diseases association with AAT deficiency...
  5. pmc The prospective association of perceived criticism with dyspnea in chronic lung disease
    Kristen E Holm
    National Jewish Health, Department of Medicine, Denver, CO, USA
    J Psychosom Res 74:450-3. 2013
    ..The objective of this study was to examine the association of perceived criticism with dyspnea in chronic obstructive pulmonary disease (COPD)...
  6. pmc The impact of age on outcomes in chronic obstructive pulmonary disease differs by relationship status
    Kristen E Holm
    Department of Medicine, National Jewish Health, 1400 Jackson Street, Denver, CO, 80206, USA
    J Behav Med 37:654-63. 2014
    ..Results suggest that individuals who develop a chronic illness at a young age, particularly those who are single, may be more likely to have worse psychological and clinical outcomes. ..
  7. pmc Differences in adjustment between individuals with alpha-1 antitrypsin deficiency (AATD)-associated COPD and non-AATD COPD
    Kristen E Holm
    Department of Medicine, National Jewish Health, Denver, CO 80206, USA
    COPD 10:226-34. 2013
    ..Resources available to persons with AATD-associated COPD, such as being in a serious relationship and having higher education, may offset the effect of age when considering symptoms of depression and anxiety in patients with COPD...
  8. doi request reprint Neutrophil elastase-mediated lung disease
    Robert A Sandhaus
    National Jewish Health, Denver, Colorado 80206, USA
    COPD 10:60-3. 2013
    ..In alpha-1 antitrypsin deficiency we find an experiment of nature that disrupts this protease-anti-protease balance, resulting in an increased risk of destructive lung disease...
  9. ncbi request reprint Alpha-1 antitrypsin deficiency: whom to test, whom to treat?
    Robert A Sandhaus
    Department of Medicine, National Jewish Health, Denver, Colorado 80206, USA
    Semin Respir Crit Care Med 31:343-7. 2010
    ..Additional genetic modifiers of COPD will be found, and the path set by AATD will facilitate their incorporation into our future management of COPD...
  10. doi request reprint Biochemical efficacy and safety of a new, ready-to-use, liquid alpha-1-proteinase inhibitor, GLASSIA (alpha1-proteinase inhibitor (human), intravenous)
    Robert A Sandhaus
    1National Jewish Health, Denver, CO, USA
    COPD 11:17-25. 2014
    ..The study concluded that GLASSIA, a new liquid, ready to use, formulation of A1PI, was not inferior to PROLASTIN and it was well tolerated with a safety profile comparable to PROLASTIN...
  11. pmc Alcohol use predicts ER visits in individuals with alpha-1 antitrypsin deficiency (AATD) associated COPD
    Karin F Hoth
    National Jewish Health, Department of Medicine, Denver, CO, United States
    COPD 9:417-25. 2012
    ..Neither measure of problem drinking predicted hospital admission. Screening for recent excessive alcohol use in this population may identify individuals at risk for use of costly emergency health services...
  12. pmc Risk factors for symptom onset in PI*Z alpha-1 antitrypsin deficiency
    Annyce S Mayer
    Division of Environmental and Occupational Health Sciences National Jewish Medical and Research Center, Denver, CO 80206, USA
    Int J Chron Obstruct Pulmon Dis 1:485-92. 2006
    ..Age of symptom onset has not been well studied in relationship to other environmental exposures...
  13. ncbi request reprint Results of a survey of patients with alpha-1 antitrypsin deficiency
    Charlie Strange
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Medical University of South Carolina, Charleston, 29425, USA
    Respiration 73:185-90. 2006
    ..alpha(1)-Antitrypsin deficiency (AATD) is an uncommon genetic disease which occurs in 1-2.5% of Americans with chronic obstructive pulmonary disease (COPD). Little is known about current demographics of AATD...
  14. ncbi request reprint Influenza vaccination in subjects with alpha1-antitrypsin deficiency
    Michael A Campos
    Division of Pulmonary and Critical Care Medicine, University of Miami Miller School of Medicine, PO Box 016960 R 47, Miami, FL 33101, USA
    Chest 133:49-55. 2008
    ..Influenza vaccination practices and their relation to respiratory outcomes in AATD are unknown...
  15. pmc IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency
    Dawn L DeMeo
    Brigham and Women s Hospital, Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115, USA
    Am J Respir Cell Mol Biol 38:114-20. 2008
    ..Haplotype analysis of IL10 SNPs suggested the strongest association with IL10 promoter SNPs. IL10 is likely an important modifier gene for the development of COPD in individuals with severe AAT deficiency...
  16. pmc Determinants of airflow obstruction in severe alpha-1-antitrypsin deficiency
    Dawn L DeMeo
    Channing Laboratory, 181 Longwood Avenue, Boston, Massachusetts 02115, USA
    Thorax 62:806-13. 2007
    ..A study was undertaken to assess the impact of chronic bronchitis, pneumonia, asthma and sex on the development of COPD in individuals with severe AAT deficiency...
  17. ncbi request reprint Alpha-1 antitrypsin deficiency: doing the right thing (or start kissing those frogs)
    Robert A Sandhaus
    COPD 3:123-4. 2006
  18. ncbi request reprint Trends in the diagnosis of symptomatic patients with alpha1-antitrypsin deficiency between 1968 and 2003
    Michael A Campos
    Division of Pulmonary and Critical Care Medicine, University of Miami School of Medicine, PO Box 016960 R 47, Miami, FL 33101, USA
    Chest 128:1179-86. 2005
    ..To support current guidelines recommending AATD testing of all individuals with COPD, we analyzed the diagnostic experience of a large cohort of symptomatic patients with AATD...
  19. pmc Environmental, occupational, and genetic risk factors for alpha-1 antitrypsin deficiency
    Richard R Sharp
    Baylor College of Medicine, Houston, Texas, USA
    Environ Health Perspect 111:1749-52. 2003
    ....