Impact of an informed choice invitation on uptake of screening for diabetes in primary care (DICISION): trial protocolEleanor Mann
Psychology Department at Guy s, Guy s Campus, London, SE1 9RT, UK
BMC Public Health 9:63. 2009
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Joint effects of the N-acetyltransferase 1 and 2 (NAT1 and NAT2) genes and smoking on bladder carcinogenesis: a literature-based systematic HuGE review and evidence synthesisSimon Sanderson
Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge, United Kingdom
Am J Epidemiol 166:741-51. 2007
..73 (95% CI: 1.70, 4.31). The importance of considering joint effects between genetic and environmental factors in the etiology of common complex diseases is underlined...
Inherited cardiovascular conditions: the challenges of genomic medicineH Burton
PHG Foundation, 2 Worts Causeway, Cambridge CB1 8RN, UK
Heart 96:474-6. 2010
..The report will also be of relevance internationally, wherever cardiologists and geneticists aim to provide care for these patients and their families...
- Republished research: effectiveness of physical activity promotion based in primary care: systematic review and meta-analysis of randomised controlled trials
Gillian Orrow
General Practice and Primary Care Research Unit, Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge CB2 0SR, UK
Br J Sports Med 47:27. 2013
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- Array CGH in patients with learning disability (mental retardation) and congenital anomalies: updated systematic review and meta-analysis of 19 studies and 13,926 subjects
Gurdeep S Sagoo
MRC Biostatistics Unit, University of Cambridge, Cambridge, United Kingdom
Genet Med 11:139-46. 2009
..However, given that this technology also identifies false positives at a similar rate to causal variants, caution in clinical practice should be advised...
- Effectiveness of physical activity promotion based in primary care: systematic review and meta-analysis of randomised controlled trials
Gillian Orrow
General Practice and Primary Care Research Unit, Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge CB2 0SR, UK
BMJ 344:e1389. 2012
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- Array-based comparative genomic hybridization for investigating chromosomal abnormalities in patients with learning disability: systematic review meta-analysis of diagnostic and false-positive yields
Subu Subramonia Iyer
Public Health Genetics Unit, Cambridge, United Kingdom
Genet Med 9:74-9. 2007
..This paper reports the results of an evaluation of this emerging technology and discusses the challenges faced in conducting the evaluation...
- What determines Self-Rated Health (SRH)? A cross-sectional study of SF-36 health domains in the EPIC-Norfolk cohort
Nahal Mavaddat
General Practice and Primary Care Research Unit, Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Forvie Site, Robinson Way, Cambridge CB2 0SR, UK
J Epidemiol Community Health 65:800-6. 2011
..This study aimed to determine the extent to which dimensions of physical, mental and social functioning are associated with SRH...
- Narrative review: aspirin resistance and its clinical implications
Simon Sanderson
University of Cambridge, Addenbrooke s Hospital, and Institute of Public Health, Cambridge, United Kingdom
Ann Intern Med 142:370-80. 2005
..These challenges must be met before researchers conduct studies to assess the clinical utility of testing on patient outcomes and cost-effective prescribing...
- CYP2C9 gene variants, drug dose, and bleeding risk in warfarin-treated patients: a HuGEnet systematic review and meta-analysis
Simon Sanderson
Department of Public Health and Primary Care, University of Cambridge and Cambridge Genetics Knowledge Park, Cambridge, UK
Genet Med 7:97-104. 2005
..The study objective was to examine the strength and quality of existing evidence about CYP2C9 gene variants and clinical outcomes in warfarin-treated patients...
- Thromboembolic events among adult patients with primary immune thrombocytopenia in the United Kingdom General Practice Research Database
Ameet Sarpatwari
Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB2 0SR, UK
Haematologica 95:1167-75. 2010
..The objective of this study was to evaluate the risk of thromboembolic events among adult patients with and without primary immune thrombocytopenia in the UK General Practice Research Database...
- Turning the pump handle: evolving methods for integrating the evidence on gene-disease association
Julian P T Higgins
Am J Epidemiol 166:863-6. 2007
- Needs assessment and review of services for people with inherited metabolic disease in the United Kingdom
Hilary Burton
Public Health Genetics Unit, Cambridge, UK
J Inherit Metab Dis 29:667-76. 2006
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- How can the evaluation of genetic tests be enhanced? Lessons learned from the ACCE framework and evaluating genetic tests in the United Kingdom
Simon Sanderson
University of Cambridge and Cambridge Genetics Knowledge Park, Cambridge, UK
Genet Med 7:495-500. 2005
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- Obstacles and opportunities in meta-analysis of genetic association studies
Georgia Salanti
MRC Biostatistics Unit, Cambridge, UK
Genet Med 7:13-20. 2005
..We believe that systematic review and meta-analysis has an important role to play in understanding genetic association studies and should help us to separate the wheat from the chaff...
