Laura G Sanchez-Lozada

Summary

Publications

  1. pmc Role of oxidative stress in the renal abnormalities induced by experimental hyperuricemia
    Laura G Sanchez-Lozada
    Department of Nephrology, INC Ignacio Chavez, Juan Badiano 1 14080 Mexico City, Mexico
    Am J Physiol Renal Physiol 295:F1134-41. 2008
  2. doi request reprint Dietary fructose and hypertension
    Magdalena Madero
    Department of Nephrology, INC Ignacio Chavez, Juan Badiano 1, Mexico City, Mexico
    Curr Hypertens Rep 13:29-35. 2011
  3. ncbi request reprint Mild hyperuricemia induces glomerular hypertension in normal rats
    Laura G Sanchez-Lozada
    Department of Nephrology, Instituto Nacional de Cardiologia I Chavez, 14080 Mexico City, Mexico
    Am J Physiol Renal Physiol 283:F1105-10. 2002
  4. doi request reprint Effect of febuxostat on the progression of renal disease in 5/6 nephrectomy rats with and without hyperuricemia
    Laura G Sanchez-Lozada
    Department of Nephrology, INC Ignacio Chavez, Mexico City, Mexico
    Nephron Physiol 108:p69-78. 2008
  5. ncbi request reprint Treatment with the xanthine oxidase inhibitor febuxostat lowers uric acid and alleviates systemic and glomerular hypertension in experimental hyperuricaemia
    Laura G Sanchez-Lozada
    Department of Nephrology, Instituto Nacional de Cardiologia Ignacio Chavez, Juan Badiano 1, 14080 Mexico City, Mexico
    Nephrol Dial Transplant 23:1179-85. 2008
  6. ncbi request reprint Effects of acute and chronic L-arginine treatment in experimental hyperuricemia
    Laura G Sanchez-Lozada
    Dept of Nephrology, Instituto Nacional de Cardiologia Ignacio Chavez, Juan Badiano 1 14080, Mexico City, Mexico
    Am J Physiol Renal Physiol 292:F1238-44. 2007
  7. ncbi request reprint Fructose-induced metabolic syndrome is associated with glomerular hypertension and renal microvascular damage in rats
    Laura G Sanchez-Lozada
    Dept of Nephrology, Instituto Nacional de Cardiologia Ignacio Chavez, Juan Badiano 1 14080, Mexico City, Mexico
    Am J Physiol Renal Physiol 292:F423-9. 2007
  8. ncbi request reprint Mild hyperuricemia induces vasoconstriction and maintains glomerular hypertension in normal and remnant kidney rats
    Laura G Sanchez-Lozada
    Department of Nephrology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Kidney Int 67:237-47. 2005
  9. doi request reprint Effects of febuxostat on metabolic and renal alterations in rats with fructose-induced metabolic syndrome
    Laura G Sanchez-Lozada
    Dept of Nephrology, Instituto Nacional de Cardiologia Ignacio Chavez, Juan Badiano 1, 14080 Mexico City, Mexico
    Am J Physiol Renal Physiol 294:F710-8. 2008
  10. ncbi request reprint Mycophenolate mofetil prevents arteriolopathy and renal injury in subtotal ablation despite persistent hypertension
    Edilia Tapia
    Departments of Nephrology and Pathology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Kidney Int 63:994-1002. 2003

Detail Information

Publications15

  1. pmc Role of oxidative stress in the renal abnormalities induced by experimental hyperuricemia
    Laura G Sanchez-Lozada
    Department of Nephrology, INC Ignacio Chavez, Juan Badiano 1 14080 Mexico City, Mexico
    Am J Physiol Renal Physiol 295:F1134-41. 2008
    ..Scavenging of the superoxide anion in this setting attenuates the adverse effects induced by hyperuricemia...
  2. doi request reprint Dietary fructose and hypertension
    Magdalena Madero
    Department of Nephrology, INC Ignacio Chavez, Juan Badiano 1, Mexico City, Mexico
    Curr Hypertens Rep 13:29-35. 2011
    ..Clinical and epidemiologic studies have also linked fructose consumption with hypertension. Further studies are warranted in order to understand the role of fructose in the development of hypertension...
  3. ncbi request reprint Mild hyperuricemia induces glomerular hypertension in normal rats
    Laura G Sanchez-Lozada
    Department of Nephrology, Instituto Nacional de Cardiologia I Chavez, 14080 Mexico City, Mexico
    Am J Physiol Renal Physiol 283:F1105-10. 2002
    ..Glomerular hypertension may be partially mediated by an abnormal vascular response to systemic hypertension due to arteriolopathy of the afferent arteriole...
  4. doi request reprint Effect of febuxostat on the progression of renal disease in 5/6 nephrectomy rats with and without hyperuricemia
    Laura G Sanchez-Lozada
    Department of Nephrology, INC Ignacio Chavez, Mexico City, Mexico
    Nephron Physiol 108:p69-78. 2008
    ..The effect of febuxostat (Fx), a non-purine and selective xanthine oxidase inhibitor, on glomerular microcirculatory changes in 5/6 nephrectomy (5/6 Nx) Wistar rats with and without oxonic acid (OA)-induced hyperuricemia was evaluated...
  5. ncbi request reprint Treatment with the xanthine oxidase inhibitor febuxostat lowers uric acid and alleviates systemic and glomerular hypertension in experimental hyperuricaemia
    Laura G Sanchez-Lozada
    Department of Nephrology, Instituto Nacional de Cardiologia Ignacio Chavez, Juan Badiano 1, 14080 Mexico City, Mexico
    Nephrol Dial Transplant 23:1179-85. 2008
    ..We therefore tested the hypothesis that Fx might be useful in treating hyperuricemia-induced hypertension and renal damage...
  6. ncbi request reprint Effects of acute and chronic L-arginine treatment in experimental hyperuricemia
    Laura G Sanchez-Lozada
    Dept of Nephrology, Instituto Nacional de Cardiologia Ignacio Chavez, Juan Badiano 1 14080, Mexico City, Mexico
    Am J Physiol Renal Physiol 292:F1238-44. 2007
    ..On the other hand, chronic l-Arg preserved arteriolar structures probably mediated by the antiproliferative effect of NO on vascular smooth muscle cells...
  7. ncbi request reprint Fructose-induced metabolic syndrome is associated with glomerular hypertension and renal microvascular damage in rats
    Laura G Sanchez-Lozada
    Dept of Nephrology, Instituto Nacional de Cardiologia Ignacio Chavez, Juan Badiano 1 14080, Mexico City, Mexico
    Am J Physiol Renal Physiol 292:F423-9. 2007
    ..These changes are best observed in rats administered high doses (60% diet) of fructose...
  8. ncbi request reprint Mild hyperuricemia induces vasoconstriction and maintains glomerular hypertension in normal and remnant kidney rats
    Laura G Sanchez-Lozada
    Department of Nephrology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Kidney Int 67:237-47. 2005
    ....
  9. doi request reprint Effects of febuxostat on metabolic and renal alterations in rats with fructose-induced metabolic syndrome
    Laura G Sanchez-Lozada
    Dept of Nephrology, Instituto Nacional de Cardiologia Ignacio Chavez, Juan Badiano 1, 14080 Mexico City, Mexico
    Am J Physiol Renal Physiol 294:F710-8. 2008
    ..These results provide further evidence for a pathogenic role of hyperuricemia in fructose-mediated metabolic syndrome...
  10. ncbi request reprint Mycophenolate mofetil prevents arteriolopathy and renal injury in subtotal ablation despite persistent hypertension
    Edilia Tapia
    Departments of Nephrology and Pathology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Kidney Int 63:994-1002. 2003
    ..We investigated the effects of suppressing inflammation with mycophenolate mofetil (MMF) on glomerular hemodynamics, arteriolar structural changes, and renal histologic injury in rats with subtotal renal ablation..
  11. doi request reprint Sildenafil treatment prevents glomerular hypertension and hyperfiltration in rats with renal ablation
    Edilia Tapia
    Department of Nephrology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Kidney Blood Press Res 35:273-80. 2012
    ..Sildenafil treatment ameliorates progressive renal injury resulting from extensive renal ablation; however, modifications induced by sildenafil in the glomerular hemodynamic pathophysiology of the remnant kidney have not been investigated...
  12. pmc Treatment with pyrrolidine dithiocarbamate improves proteinuria, oxidative stress, and glomerular hypertension in overload proteinuria
    Edilia Tapia
    Department of Nephrology, Instituto Nacional de Cardiologia Ignacio Chavez, Juan Badiano 1, 14080 Mexico City, Mexico
    Am J Physiol Renal Physiol 295:F1431-9. 2008
    ..Oxidative stress and inflammation may have a key role in accelerating renal injury associated with intense proteinuria...
  13. ncbi request reprint Hemodynamics of hyperuricemia
    Laura G Sanchez-Lozada
    Department of Nephrology, Instituto Nacional de Cardiologia, Ignacio Chavez, 14080 Mexico City, Mexico
    Semin Nephrol 25:19-24. 2005
    ..Lumen obliteration induced by vascular wall thickening results in severe vasoconstriction. The resulting ischemia is a potent stimulus that induces tubulointerstitial inflammation and fibrosis as well as arterial hypertension...
  14. ncbi request reprint Hormonal and cytokine effects of uric acid
    Laura G Sanchez-Lozada
    Department of Nephrology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Curr Opin Nephrol Hypertens 15:30-3. 2006
    ..In the present review, we summarize recent studies on the mechanisms involved in the uric acid deleterious effects...
  15. doi request reprint Pathophysiology of salt-sensitive hypertension: a new scope of an old problem
    Martha Franco
    Department of Nephrology, Instituto Nacional de CardiologĂ­a I Ch, Juan Badiano No 1, Mexico City, Mexico
    Blood Purif 26:45-8. 2008
    ..Thus, the renal angiotensin system in association with interstitial immune infiltrating cells may play a pivotal role in the development and maintenance of salt-sensitive hypertension...