Antithrombotic therapy in valvular heart disease--native and prosthetic: the Seventh ACCP Conference on Antithrombotic and Thrombolytic TherapyDeeb N Salem
Tufts New England Medical Center, 750 Washington St, Boston, MA 02111, USA
Chest 126:457S-482S. 2004
..For patients with bioprosthetic valves who are in sinus rhythm and do not have AF, we recommend long-term (> 3 months) therapy with aspirin, 75 to 100 mg/d (Grade 1C+)...
Waist-to-hip ratio, body mass index, and subsequent kidney disease and deathEssam F Elsayed
Nephrology Research Center, Tufts New England Medical Center, Boston, MA 02111, USA
Am J Kidney Dis 52:29-38. 2008
..Chronic kidney disease (CKD) and obesity are important public health concerns. We examined the association between anthropomorphic measures and incident CKD and mortality...
The Framingham predictive instrument in chronic kidney diseaseDaniel E Weiner
Division of Nephrology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
J Am Coll Cardiol 50:217-24. 2007
..We sought to determine the utility of the Framingham equations in individuals with chronic kidney disease (CKD)...
CKD classification based on estimated GFR over three years and subsequent cardiac and mortality outcomes: a cohort studyDaniel E Weiner
Division of Nephrology, Tufts Medical Center, 800 Washington Street, Boston, MA 02111, USA
BMC Nephrol 10:26. 2009
..It is unknown whether defining chronic kidney disease (CKD) based on one versus two estimated glomerular filtration rate (eGFR) assessments changes the prognostic importance of reduced eGFR in a community-based population...
The relationship between nontraditional risk factors and outcomes in individuals with stage 3 to 4 CKDDaniel E Weiner
Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
Am J Kidney Dis 51:212-23. 2008
..Chronic kidney disease is associated with increased risk for cardiovascular disease and mortality. Both traditional and nontraditional cardiovascular disease risk factors may contribute...
Anemia as a risk factor for cardiovascular disease and all-cause mortality in diabetes: the impact of chronic kidney diseasePanagiotis T Vlagopoulos
Division of Nephrology, Tufts-New England Medical Center, 750 Washington Street, Box 391, Boston, MA 02111, USA
J Am Soc Nephrol 16:3403-10. 2005
..66) for all-cause mortality. Anemia was not a risk factor for any outcome in those without CKD (P > 0.2 for all outcomes). In persons with diabetes, anemia is primarily a risk factor for adverse outcomes in those who also have CKD...
Cardiovascular outcomes and all-cause mortality: exploring the interaction between CKD and cardiovascular diseaseDaniel E Weiner
Division of Nephrology, Department of Internal Medicine, Tufts New England Medical Center, Boston, MA 02111, USA
Am J Kidney Dis 48:392-401. 2006
..Concurrently, CVD may promote CKD, resulting in a vicious cycle. We evaluated this hypothesis by exploring whether CKD and CVD have an additive or synergistic effect on future cardiovascular and mortality outcomes...
Kidney disease, Framingham risk scores, and cardiac and mortality outcomesDaniel E Weiner
Division of Nephrology, Tufts New England Medical Center, Boston, Mass 02111, USA
Am J Med 120:552.e1-8. 2007
..The Framingham equations were developed to predict incident coronary heart disease. It remains unknown how the presence of chronic kidney disease affects their performance...
Lowest systolic blood pressure is associated with stroke in stages 3 to 4 chronic kidney diseaseDaniel E Weiner
Division of Nephrology, Box 391, Tufts New England Medical Center, Boston, MA 02111, USA
J Am Soc Nephrol 18:960-6. 2007
..CKD and elevated SBP are independent risk factors for incident stroke. In CKD, individuals with the lowest BP are at increased risk for stroke. This pattern is not seen in the general population...
Effects of anemia and left ventricular hypertrophy on cardiovascular disease in patients with chronic kidney diseaseDaniel E Weiner
Division of Nephrology, Tufts-New England Medical Center, 750 Washington Street, Box 391, Boston, MA 02111, USA
J Am Soc Nephrol 16:1803-10. 2005
..15 [95% CI, 2.62 to 6.56] and 3.92 [95% CI, 2.05 to 7.48]; P = 0.02 and 0.01 for interaction term, respectively). The combination of anemia and LVH in CKD identifies a high-risk population...
Uric acid and incident kidney disease in the communityDaniel E Weiner
Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
J Am Soc Nephrol 19:1204-11. 2008
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Valvular and structural heart disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)Deeb N Salem
Department of Medicine, Tufts New England Medical Center, 750 Washington Street, Boston, MA 02111, USA
Chest 133:593S-629S. 2008
..For patients with infective endocarditis, we recommend against antithrombotic therapy, unless a separate indication exists (Grade 1B)...
Does error and adverse event reporting by physicians and nurses differ?Ethan J Rowin
Tufts University School of Medicine, Boston, USA
Jt Comm J Qual Patient Saf 34:537-45. 2008
..In a descriptive study of a standardized, Web-based reporting system, the reporting practices of physicians and nurses were compared...
Kidney disease as a risk factor for recurrent cardiovascular disease and mortalityDaniel E Weiner
Division of Nephrology, Tufts-New England Medical Center, Boston, MA 02111, USA
Am J Kidney Dis 44:198-206. 2004
..CONCLUSION: The presence of CKD in a community-based population with preexisting CVD is associated with an increased risk for recurrent CVD outcomes. This increased risk persists after adjustment for traditional CVD risk factors...
Voluntary electronic reporting of laboratory errors: an analysis of 37,532 laboratory event reports from 30 health care organizationsLaura K Snydman
Tufts Medical Center, Boston, MA 02111, USA
Am J Med Qual 27:147-53. 2012
..Laboratory errors often are caused by events that precede specimen arrival in the lab and should be preventable with a better labeling processes and education. Most laboratory errors do not lead to patient harm...
Inpatient medical errors involving glucose-lowering medications and their impact on patients: review of 2,598 incidents from a voluntary electronic error-reporting databaseRenee E Amori
Division of Endocrinology, Diabetes, and Metabolism, Tufts New England Medical Center, Boston, Massachusetts, USA
Endocr Pract 14:535-42. 2008
..To describe characteristics of inpatient medical errors involving hypoglycemic medications and their impact on patient care...
Should beta-blockers be given to patients with heart disease and peanut-induced anaphylaxis? A decision analysisJohn A TenBrook
Division of Clinical Decision Making, Informatics, and Telemedicine, Department of Medicine, Tufts New England Medical Center, 750 Washington Street, Boston, MA 02111, USA
J Allergy Clin Immunol 113:977-82. 2004
..Beta-blocker therapy postmyocardial infarction is generally recommended because it reduces mortality. However, beta-blockers may increase anaphylaxis mortality in the growing population of patients with peanut-induced anaphylaxis...
Enalapril treatment and hospitalization with atrial tachyarrhythmias in patients with left ventricular dysfunctionAlawi A Alsheikh-Ali
Tufts-New England Medical Center, Department of Medicine, Division of Cardiolgy, Boston, Mass, USA
Am Heart J 147:1061-5. 2004
..4 per 1000 patient-years in the placebo group (RR, 0.64; 95% CI, 0.48-0.85; P =.002). CONCLUSION: Enalapril is associated with a decreased incidence of hospitalization with atrial tachyarrhythmias in patients with LV dysfunction...
Voluntary electronic reporting of medical errors and adverse events. An analysis of 92,547 reports from 26 acute care hospitalsCatherine E Milch
Department of Medicine and the Institute for Clinical Research and Health Policy Studies, Tufts-New England Medical Center, Boston, MA 02111, USA
J Gen Intern Med 21:165-70. 2006
..CONCLUSIONS: An e-ERS provides an accessible venue for reporting medical errors, adverse events, and near misses. The wide variation in reporting rates among hospitals, and very low reporting rates by physicians, requires investigation...
A meta-analysis of randomized controlled trials comparing coronary artery bypass graft with percutaneous transluminal coronary angioplasty: one- to eight-year outcomesStuart N Hoffman
Department of Medicine, Division of Clinical Decision Making, Informatics, and Telemedicine, Tufts-New England Medical Center, Boston, Massachusetts 02111, USA
J Am Coll Cardiol 41:1293-304. 2003
..For patients with multivessel disease, CABG provided a survival advantage at five to eight years, and for diabetics, a survival advantage at four years. The addition of stents reduced the need for repeat revascularization by about half...
Kidney function and mortality among patients with left ventricular systolic dysfunctionNadia A Khan
Division of Internal Medicine, University of British Columbia, Department of Medicine, 620 B, 1081 Burrard Street, Vancouver, BC, Canada, V6Z 1Y6
J Am Soc Nephrol 17:244-53. 2006
..Rate of decline in kidney function is a strong predictor of increased mortality in this population, independent of worsening heart failure and baseline kidney function...