Dronedarone in atrial fibrillation: the aftermath of the PALLAS trialAmar M Salam
Consultant Cardiologist, Hamad Medical Corporation, PO Box 3050, Doha, Qatar
Expert Rev Cardiovasc Ther 10:1345-9. 2012
..In this article, the trial is presented and the significance and practical implications of the results in the management of older patients with AF briefly discussed...
The therapeutic potential of PCSK9 inhibition in primary dyslipidemia, the example from SAR236553/REGN727Amar M Salam
Hamad Medical Corp, PO Box 3050, Doha, Qatar
Expert Opin Investig Drugs 21:1585-8. 2012
..In this report the trial is discussed along with the significance of the results in guiding further research in PCSK9 inhibition...
- Angiotensin receptor blockers in acute myocardial infarction
Amar M Salam
Department of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation, Doha, Qatar
Expert Opin Investig Drugs 13:427-30. 2004
..This article discusses this important study and its implications for the clinical management of these high-risk patients...
- The therapeutic potential of ximelagatran to become the anticoagulant of choice in medicine: a review of recently completed clinical trials
Amar M Salam
Hamad Medical Corporation, Department of Cardiology and Cardiovascular Surgery, PO Box 3050, Doha, Qatar
Expert Opin Pharmacother 5:1423-30. 2004
..This article reviews these recent clinical trials and explores the therapeutic potential of ximelagatran to become the oral anticoagulant of first choice in medicine...
- Lipid-lowering therapy in patients with average cholesterol and high cardiovascular risk, insights from the Heart Protection Study
Amar M Salam
Department of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation, PO Box 3050, Doha, Qatar
Cardiovasc Drugs Ther 18:387-9. 2004
..In this report the study is presented with the significance and practical implications of the results briefly discussed...
- The therapeutic potential of vasopressin in cardiopulmonary resuscitation
Amar Mohammad Salam
Hamad Medical Corporation, Department of Cardiology and Cardiovascular Surgery, PO Box 3050, Doha, Qatar
Expert Opin Pharmacother 6:517-20. 2005
- The benefits of abciximab questioned in percutaneous coronary interventions following pretreatment with high-dose clopidogrel
Amar M Salam
Department of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation, P.O.Box 3050, Doha, Qatar
Expert Opin Investig Drugs 14:335-8. 2005
- Acute myocardial infarction in the first trimester of pregnancy
Amar M Salam
Department of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation, Doha, Qatar
Asian Cardiovasc Thorac Ann 13:175-7. 2005
..In this report, a 43-year-old lady with acute anterior myocardial infarction in her eighth week of pregnancy is presented. The challenges involved in diagnosing this condition in pregnancy are briefly discussed...
- The therapeutic potential of vasopressin receptor antagonists in congestive heart failure
Amar M Salam
Department of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation, PO Box 3050, Doha, Qatar
Expert Opin Investig Drugs 14:687-91. 2005
..These results make an important contribution to heart failure research, and offer an insight into the future role of vasopressin antagonism in the treatment of congestive heart failure...
- Managing atrial fibrillation in older people: a comparison of two treatment strategies
Amar M Salam
Department of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation, Doha, Qatar
J Am Geriatr Soc 51:1806-7. 2003
- Rate control versus rhythm control for the management of atrial fibrillation: the verdict of the AFFIRM trial
Amar M Salam
Department of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation, Doha, Qatar
Expert Opin Investig Drugs 12:1231-7. 2003
..In this article, the long awaited verdict of the AFFIRM study with its implications for the clinical management of patients with atrial fibrillation is discussed...
- Clinical trials evaluating angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in the setting of acute myocardial infarction
Amar M Salam
Department of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation, Doha, Qatar
Expert Opin Investig Drugs 12:501-7. 2003
..In this article, an evidence-based review of these major trials and suggestions for clinical application are presented...
- Is there a role for oral blockade of platelet glycoprotein IIb/IIIa receptors in coronary and cerebrovascular disease?
Amar M Salam
Department of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation, PO Box 3050, Doha, Qatar
Expert Opin Investig Drugs 12:1709-12. 2003
..Further research to elucidate the mechanism of this increased fatality risk is warranted before any further clinical studies with the oral GP IIb/IIIa inhibitors can be ethically justified...
- Expanding indications of statins; implications of the Heart Protection Study
Amar M Salam
Department of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation, Doha, Qatar
Expert Opin Investig Drugs 12:509-13. 2003
..In this report, the paper is discussed with the significance of the results outlined in view of existing evidence from previously published trials. In addition, ongoing trials and future directions are explored...
- Low molecular weight heparins combined with platelet glycoprotein IIb/IIIa inhibitors in the management of acute coronary syndromes
Amar M Salam
Department of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation, P O Box 3050, Doha, Qatar
Expert Opin Investig Drugs 12:1567-70. 2003
..Results of other ongoing studies of LMWH combinations with other GP IIb/IIIa inhibitors and in the setting of percutaneous coronary intervention are awaited...
- What are the best first-line antihypertensives: answers and more questions from the ALLHAT study
Amar Mohammad Salam
Department of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation, P O Box 3050, Doha, Qatar
Expert Opin Investig Drugs 12:879-85. 2003
..Additionally, further questions raised by the ALLHAT study are explored with ongoing studies, and future directions with which to answer these emerging new questions are outlined...
- Selective aldosterone blockade with eplerenone in patients with congestive heart failure
Amar M Salam
Department of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation, P O Box 3050, Doha, Qatar
Expert Opin Investig Drugs 12:1423-7. 2003
..Further research is warranted concerning the possible benefits of this new agent in disease states other than congestive heart failure in which an activated renin-angiotensin-aldosterone system system has been implicated...
- Evolving role of bivalirudin in percutaneous coronary interventions; impact of the REPLACE-2 study
Amar M Salam
Department of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation, Doha, Qatar
Expert Opin Investig Drugs 12:1027-33. 2003
..Additionally, the implications of the REPLACE-2 study in establishing where bivalirudin fits into our current interventional cardiology practice and future directions are presented...
- Platelet glycoprotein IIb/IIIa antagonists in clinical trials for the treatment of coronary artery disease
Amar M Salam
Department of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation, Doha, Qatar
Expert Opin Investig Drugs 11:1645-58. 2002
..In this report we give an overview of these clinical trials...
- Gemella morbillorum endocarditis
Hussam Al Soub
Department of Internal Medicine, Hamad Medical Corporation, Doha, Qatar
Saudi Med J 24:1135-7. 2003
..G.morbillorum endocarditis is probably under recognized, and has not been reported from our region. The case is described, and problems in the identification of the organism are discussed...
- Intensive lipid-lowering therapy in coronary artery disease: implications of the REVERSAL and PROVE-IT trials
Amar M Salam
Department of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation, PO Box 3050, Doha, Quatar
Expert Opin Investig Drugs 13:707-13. 2004
..This article reviews the implications of these two studies in the management of patients with CAD. In addition, other ongoing trials and future directions are explored...
- Impact of coronary artery stents on mortality and nonfatal myocardial infarction: meta-analysis of randomized trials comparing a strategy of routine stenting with that of balloon angioplasty
Jassim Al Suwaidi
Department of Cardiology and Cardiovascular Surgery, Hamad General Hospital and Hamad Medical Corporation, Doha, Qatar
Am Heart J 147:815-22. 2004
..8 months. Patients who underwent stent placement had a significantly lower risk of major adverse cardiac events only when target revascularization is included as an end point...
- Contrast-enhanced 64-section coronary multidetector CT angiography versus conventional coronary angiography for stent assessment
K M Das
Departments of Radiology, Cardiology, and Medical Research, Hamad Medical Corporation, Hamad Medical St, Doha, Qatar
Radiology 245:424-32. 2007
..To prospectively evaluate the accuracy of 64-section computed tomography (CT) for diagnosis of stent restenosis, by using conventional coronary angiography as the reference standard...
- Acute myocardial infarction in a professional diver after jellyfish sting
Amar M Salam
Department of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation, Doha, Sate of Qatar
Mayo Clin Proc 78:1557-60. 2003
..Acute myocardial infarction should be considered in patients who experience chest pain or have hemodynamic compromise after jellyfish envenomation...
