Shiv Saidha

Summary

Publications

  1. doi request reprint Multiple sclerosis exceptionally presenting as parkinsonism responds to intravenous methylprednisolone
    S Saidha
    Department of Neurology, Mercy University Hospital, Grenville Place, Cork, Ireland
    J Clin Neurosci 17:654-5. 2010
  2. doi request reprint Relationships between retinal axonal and neuronal measures and global central nervous system pathology in multiple sclerosis
    Shiv Saidha
    Department of Neurology, Johns Hopkins University, Baltimore, MD, USA
    JAMA Neurol 70:34-43. 2013
  3. pmc Microcystic macular oedema, thickness of the inner nuclear layer of the retina, and disease characteristics in multiple sclerosis: a retrospective study
    Shiv Saidha
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Lancet Neurol 11:963-72. 2012
  4. pmc Spectrum of peripheral neuropathies associated with surgical interventions; A neurophysiological assessment
    Shiv Saidha
    Department of Neurophysiology, Cork University Hospital, Cork, Ireland
    J Brachial Plex Peripher Nerve Inj 5:9. 2010
  5. pmc Optical coherence tomography segmentation reveals ganglion cell layer pathology after optic neuritis
    Stephanie B Syc
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Brain 135:521-33. 2012
  6. pmc Active MS is associated with accelerated retinal ganglion cell/inner plexiform layer thinning
    John N Ratchford
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Neurology 80:47-54. 2013
  7. doi request reprint Visual dysfunction in multiple sclerosis correlates better with optical coherence tomography derived estimates of macular ganglion cell layer thickness than peripapillary retinal nerve fiber layer thickness
    Shiv Saidha
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, USA
    Mult Scler 17:1449-63. 2011
  8. doi request reprint Detection of clinical and subclinical retinal abnormalities in neurosarcoidosis with optical coherence tomography
    Christopher Eckstein
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    J Neurol 259:1390-8. 2012
  9. doi request reprint In vivo assessment of retinal neuronal layers in multiple sclerosis with manual and automated optical coherence tomography segmentation techniques
    Michaela A Seigo
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    J Neurol 259:2119-30. 2012
  10. pmc In vivo identification of morphologic retinal abnormalities in neuromyelitis optica
    Elias S Sotirchos
    From the Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Neurology 80:1406-14. 2013

Collaborators

  • Jiwon Oh
  • Daniel S Reich
  • Seth A Smith
  • Min Chen
  • Jeffrey M Gelfand
  • Navid Shiee
  • Ari J Green
  • Carlos A Pardo
  • QUAN D NGUYEN
  • Peter A Calabresi
  • Elias S Sotirchos
  • Stephanie B Syc
  • Christopher Eckstein
  • John N Ratchford
  • Elliot M Frohman
  • Michaela A Seigo
  • Laura J Balcer
  • Scott D Newsome
  • Jonathan D Oakley
  • Michael Levy
  • Ciprian M Crainiceanu
  • Teresa C Frohman
  • E tona Ford
  • Jannelle J Aquino
  • Mary K Durbin
  • Scott A Meyer
  • Michaela Seigo
  • Gita Byraiah
  • Amy Conger
  • Christina V Warner
  • Mohamed A Ibrahim
  • Yasir Jamal Sepah
  • Gerald V Raymond
  • Maureen A Mealy
  • Daniel M Harrison
  • Srilakshmi Sharma
  • Scott Newsome
  • Aleksandra Babiarz
  • Aleksandra Stankiewicz
  • Sheena K Farrell
  • Aleksandra M Stankiewicz
  • Girish Hiremath
  • Esther R Bisker

Detail Information

Publications20

  1. doi request reprint Multiple sclerosis exceptionally presenting as parkinsonism responds to intravenous methylprednisolone
    S Saidha
    Department of Neurology, Mercy University Hospital, Grenville Place, Cork, Ireland
    J Clin Neurosci 17:654-5. 2010
    ..This patient illustrates that the clinical presentation and progression of MS may rarely be characterised by predominating parkinsonian features which are reversible by treatment with intravenous methylprednisolone and interferon beta1a...
  2. doi request reprint Relationships between retinal axonal and neuronal measures and global central nervous system pathology in multiple sclerosis
    Shiv Saidha
    Department of Neurology, Johns Hopkins University, Baltimore, MD, USA
    JAMA Neurol 70:34-43. 2013
    ....
  3. pmc Microcystic macular oedema, thickness of the inner nuclear layer of the retina, and disease characteristics in multiple sclerosis: a retrospective study
    Shiv Saidha
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Lancet Neurol 11:963-72. 2012
    ..We aimed to determine whether MMO of the INL, and increased thickness of the INL are associated with disease activity or disability progression...
  4. pmc Spectrum of peripheral neuropathies associated with surgical interventions; A neurophysiological assessment
    Shiv Saidha
    Department of Neurophysiology, Cork University Hospital, Cork, Ireland
    J Brachial Plex Peripher Nerve Inj 5:9. 2010
    ..The aim of this study was to classify post-operative neuropathies and the procedures associated with them...
  5. pmc Optical coherence tomography segmentation reveals ganglion cell layer pathology after optic neuritis
    Stephanie B Syc
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Brain 135:521-33. 2012
    ....
  6. pmc Active MS is associated with accelerated retinal ganglion cell/inner plexiform layer thinning
    John N Ratchford
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Neurology 80:47-54. 2013
    ....
  7. doi request reprint Visual dysfunction in multiple sclerosis correlates better with optical coherence tomography derived estimates of macular ganglion cell layer thickness than peripapillary retinal nerve fiber layer thickness
    Shiv Saidha
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, USA
    Mult Scler 17:1449-63. 2011
    ..Despite this, clinical correlations of retinal neuronal layers remain largely unexplored in MS...
  8. doi request reprint Detection of clinical and subclinical retinal abnormalities in neurosarcoidosis with optical coherence tomography
    Christopher Eckstein
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    J Neurol 259:1390-8. 2012
    ..Longitudinal NS studies utilizing OCT are warranted...
  9. doi request reprint In vivo assessment of retinal neuronal layers in multiple sclerosis with manual and automated optical coherence tomography segmentation techniques
    Michaela A Seigo
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    J Neurol 259:2119-30. 2012
    ..Fully automated, fully manual and computer-assisted manual OCT segmentation techniques compare closely, highlighting the utility of accurate and time-efficient automated segmentation outcomes in MS clinical trials...
  10. pmc In vivo identification of morphologic retinal abnormalities in neuromyelitis optica
    Elias S Sotirchos
    From the Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Neurology 80:1406-14. 2013
    ..To assess eyes with neuromyelitis optica (NMO) for morphologic retinal abnormalities utilizing high-definition optical coherence tomography (OCT) imaging...
  11. doi request reprint Multiparametric MRI correlates of sensorimotor function in the spinal cord in multiple sclerosis
    Jiwon Oh
    Department of Neurology, Johns Hopkins University, 600 N Wolfe Street, Pathology 627, Baltimore, MD 21287, USA
    Mult Scler 19:427-35. 2013
    ..Using quantitative MRI indices sensitive to early and late microstructural changes in the spinal cord, we searched for the presence of better correlations between MRI measures and clinical status in MS...
  12. doi request reprint Comparison of point estimates and average thicknesses of retinal layers measured using manual optical coherence tomography segmentation for quantification of retinal neurodegeneration in multiple sclerosis
    Elias S Sotirchos
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Curr Eye Res 38:224-8. 2013
    ..Additionally, we examined the correlation of manual segmentation-derived measures of composite layers with average thickness measures derived from automated 3-D segmentation of the macular cube...
  13. doi request reprint Primary retinal pathology in multiple sclerosis as detected by optical coherence tomography
    Shiv Saidha
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Brain 134:518-33. 2011
    ..Patients with inner and outer nuclear layer pathology have more rapid disability progression and thus retinal neuronal pathology may be a harbinger of a more aggressive form of multiple sclerosis...
  14. pmc The impact of utilizing different optical coherence tomography devices for clinical purposes and in multiple sclerosis trials
    Christina V Warner
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 6:e22947. 2011
    ....
  15. pmc Spinal cord quantitative MRI discriminates between disability levels in multiple sclerosis
    Jiwon Oh
    Department of Neurology, Johns Hopkins University, Baltimore, USA
    Neurology 80:540-7. 2013
    ..We aimed to assess whether quantitative diffusion tensor and magnetization transfer imaging measures in the SC can distinguish MS cases of comparable lesion burdens with high and low disability...
  16. pmc Quantitative MRI demonstrates abnormality of the fornix and cingulum in multiple sclerosis
    Stephanie B Syc
    Department of Neurology, Johns Hopkins University, School of Medicine, Baltimore, MD 21287, USA
    Mult Scler Int 2013:838719. 2013
    ..Lower PASAT-3 scores were associated with lower cingulum FA and higher MD and . . Cognitive dysfunction in MS may involve damage to a widespread network of brain structures, including white-matter pathways within the limbic system...
  17. doi request reprint Optical coherence tomography in x-linked adrenoleukodystrophy
    Jannelle J Aquino
    Department of Neurology, Johns Hopkins University, Baltimore, Maryland
    Pediatr Neurol 49:182-4. 2013
    ....
  18. doi request reprint A differential diagnosis of central nervous system demyelination: beyond multiple sclerosis
    Christopher Eckstein
    Department of Neurology, University of South Alabama College of Medicine, Mobile, AL, USA
    J Neurol 259:801-16. 2012
    ..In addition, we review relevant features of other CNS inflammatory disorders that may mimic MS, including Sjögren's syndrome, systemic lupus erythematosus, Behçet's disease, and primary CNS vasculitis...
  19. doi request reprint New and emerging disease modifying therapies for multiple sclerosis
    Shiv Saidha
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Ann N Y Acad Sci 1247:117-37. 2012
    ..In this review, we describe the known mechanisms of action, efficacy, and side-effect profiles of new and emerging MS DMDs...
  20. pmc Etiology of sarcoidosis: does infection play a role?
    Shiv Saidha
    Richard T Johnson Division of Neuroimmunology and Neurological Infections, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Yale J Biol Med 85:133-41. 2012
    ..In this review, we describe the known histologic and immunologic features of sarcoidosis and discuss the evidence supporting a role for infectious processes in the pathogenesis of sarcoidosis...