Tamer M Said

Summary

Publications

  1. ncbi request reprint Evaluation of sperm recovery following annexin V magnetic-activated cell sorting separation
    Tamer M Said
    Centre for Advanced Research in Human Reproduction, Infertility and Sexual Function, Glickman Urological Institute and Department of Obstetrics Gynecology, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Reprod Biomed Online 13:336-9. 2006
  2. ncbi request reprint Effects of magnetic-activated cell sorting on sperm motility and cryosurvival rates
    Tamer M Said
    Center for Advanced Research in Human Reproduction, Infertility and Sexual Function, Glickman Urological Institute, Cleveland, Ohio 44195, USA
    Fertil Steril 83:1442-6. 2005
  3. ncbi request reprint Advantage of combining magnetic cell separation with sperm preparation techniques
    Tamer M Said
    Center for Advanced Research in Human Reproduction, Infertility and Sexual Function, Glickman Urological Institute and Department of Obstetrics Gynecology, Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk A19 1, Cleveland, OH 44195, USA
    Reprod Biomed Online 10:740-6. 2005
  4. ncbi request reprint Prevention of oxidative stress injury to sperm
    Ashok Agarwal
    Center for Advanced Research in Human Reproduction, Infertility and Sexual Function, Glickman Urological Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Androl 26:654-60. 2005
  5. ncbi request reprint Oxidative stress, DNA damage and apoptosis in male infertility: a clinical approach
    Ashok Agarwal
    Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, Glickman Urological Institute, Department of Obstetrics and Gynecology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    BJU Int 95:503-7. 2005
  6. ncbi request reprint Novel association between sperm deformity index and oxidative stress-induced DNA damage in infertile male patients
    Tamer M Said
    Center for Advanced Research in Human Reproduction, Infertility and Sexual Function, Glickman Urological Institute, Department of Obstetrics Gynecology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk A19 1, Cleveland, OH 44195, USA
    Asian J Androl 7:121-6. 2005
  7. ncbi request reprint Human sperm superoxide anion generation and correlation with semen quality in patients with male infertility
    Tamer M Said
    Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, Glickman Urological Institute and Department of Obstetrics and Gynecology, The Cleveland Clinic Foundation, OH 44195, USA
    Fertil Steril 82:871-7. 2004
  8. ncbi request reprint Impact of sperm morphology on DNA damage caused by oxidative stress induced by beta-nicotinamide adenine dinucleotide phosphate
    Tamer M Said
    Center for Advanced Research in Human Reproduction, Infertility and Sexual Function, The Cleveland Clinic Foundation, Ohio 44195, USA
    Fertil Steril 83:95-103. 2005
  9. ncbi request reprint Relationship between semen quality and tobacco chewing in men undergoing infertility evaluation
    Tamer M Said
    Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, Glickman Urological Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Fertil Steril 84:649-53. 2005
  10. ncbi request reprint Implications of systemic malignancies on human fertility
    Ashok Agarwal
    Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, Glickman Urological Institute and Department of Obstetrics Gynecology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Reprod Biomed Online 9:673-9. 2004

Collaborators

Detail Information

Publications24

  1. ncbi request reprint Evaluation of sperm recovery following annexin V magnetic-activated cell sorting separation
    Tamer M Said
    Centre for Advanced Research in Human Reproduction, Infertility and Sexual Function, Glickman Urological Institute and Department of Obstetrics Gynecology, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Reprod Biomed Online 13:336-9. 2006
    ..Separating a distinctive population of non-apoptotic spermatozoa with intact membranes may optimize the outcome of assisted reproduction...
  2. ncbi request reprint Effects of magnetic-activated cell sorting on sperm motility and cryosurvival rates
    Tamer M Said
    Center for Advanced Research in Human Reproduction, Infertility and Sexual Function, Glickman Urological Institute, Cleveland, Ohio 44195, USA
    Fertil Steril 83:1442-6. 2005
    ..To evaluate the effect of magnetic-activated cell sorting in cryopreservation-thawing protocols on sperm motility and cryosurvival rate...
  3. ncbi request reprint Advantage of combining magnetic cell separation with sperm preparation techniques
    Tamer M Said
    Center for Advanced Research in Human Reproduction, Infertility and Sexual Function, Glickman Urological Institute and Department of Obstetrics Gynecology, Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk A19 1, Cleveland, OH 44195, USA
    Reprod Biomed Online 10:740-6. 2005
    ..This study clearly shows the advantage of integrating magnetic cell sorting as a part of sperm preparation, which in turn may positively affect the success rates of assisted reproductive techniques...
  4. ncbi request reprint Prevention of oxidative stress injury to sperm
    Ashok Agarwal
    Center for Advanced Research in Human Reproduction, Infertility and Sexual Function, Glickman Urological Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Androl 26:654-60. 2005
  5. ncbi request reprint Oxidative stress, DNA damage and apoptosis in male infertility: a clinical approach
    Ashok Agarwal
    Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, Glickman Urological Institute, Department of Obstetrics and Gynecology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    BJU Int 95:503-7. 2005
  6. ncbi request reprint Novel association between sperm deformity index and oxidative stress-induced DNA damage in infertile male patients
    Tamer M Said
    Center for Advanced Research in Human Reproduction, Infertility and Sexual Function, Glickman Urological Institute, Department of Obstetrics Gynecology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk A19 1, Cleveland, OH 44195, USA
    Asian J Androl 7:121-6. 2005
    ..To investigate the impact of abnormal sperm morphology using the sperm deformity index (SDI) on reactive oxygen species (ROS) production and its correlation with sperm DNA damage...
  7. ncbi request reprint Human sperm superoxide anion generation and correlation with semen quality in patients with male infertility
    Tamer M Said
    Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, Glickman Urological Institute and Department of Obstetrics and Gynecology, The Cleveland Clinic Foundation, OH 44195, USA
    Fertil Steril 82:871-7. 2004
    ..generation in infertile men and determine whether sperm quality is correlated with levels of ROS triggered by the exogenous reduced form of beta nicotinamide adenine dinucleotide phosphate (NADPH)...
  8. ncbi request reprint Impact of sperm morphology on DNA damage caused by oxidative stress induced by beta-nicotinamide adenine dinucleotide phosphate
    Tamer M Said
    Center for Advanced Research in Human Reproduction, Infertility and Sexual Function, The Cleveland Clinic Foundation, Ohio 44195, USA
    Fertil Steril 83:95-103. 2005
    ..To investigate the role of DNA damage induced by beta-nicotinamide adenine dinucleotide phosphate (NADPH) in human spermatozoa...
  9. ncbi request reprint Relationship between semen quality and tobacco chewing in men undergoing infertility evaluation
    Tamer M Said
    Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, Glickman Urological Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Fertil Steril 84:649-53. 2005
    ..The objective of our study was to assess the relationship between tobacco chewing in these Indian men--who were part of an infertile couple--and their sperm characteristics...
  10. ncbi request reprint Implications of systemic malignancies on human fertility
    Ashok Agarwal
    Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, Glickman Urological Institute and Department of Obstetrics Gynecology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Reprod Biomed Online 9:673-9. 2004
    ..However, there are some ethical issues that should be considered before offering patients any of these options...
  11. ncbi request reprint Infliximab may reverse the toxic effects induced by tumor necrosis factor alpha in human spermatozoa: an in vitro model
    Tamer M Said
    Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Fertil Steril 83:1665-73. 2005
    ..To examine the toxic effects of tumor necrosis factor alpha (TNF-alpha) on ejaculated spermatozoa and evaluate the ability of infliximab to reverse these effects...
  12. ncbi request reprint Inter-sample variability in post-thaw human spermatozoa
    Kiran P Nallella
    Center for Advanced Research in Human Reproduction, Infertility and Sexual Function, Glickman Urological Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Cryobiology 49:195-9. 2004
    ..Further research is necessary to understand the mechanism(s) responsible for this variability. This may also assist clinicians utilize semen samples with optimum semen quality in ART procedures...
  13. ncbi request reprint Chemiluminescence technique for measuring reactive oxygen species
    Ashok Agarwal
    Centre for Advanced Research in Human Reproduction, Infertility and Sexual Function, Glickman Urological Institute and Department of Obstetrics Gynecology, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Reprod Biomed Online 9:466-8. 2004
    ..A wide range of luminometers are available in the market, and laboratories should select the instruments that suit their individual needs...
  14. ncbi request reprint Role of total antioxidant capacity in the differential growth of human embryos in vitro
    Mohamed Bedaiwy
    Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Fertil Steril 86:304-9. 2006
    ..The objective of this study was to examine the relationship of early human embryonic development parameters with day 1 culture media total antioxidant levels (day 1 TAC)...
  15. ncbi request reprint Oxidative stress in an assisted reproductive techniques setting
    Ashok Agarwal
    Center for Advanced Research in Human Reproduction, Infertility and Sexual Function, Glickman Urological Institute and Department of Obstetrics Gynecology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Fertil Steril 86:503-12. 2006
    ..The impact of oxidative stress on ART outcome and the different strategies designed to prevent it are also discussed...
  16. doi request reprint Association of sperm apoptosis and DNA ploidy with sperm chromatin quality in human spermatozoa
    Reda Z Mahfouz
    Department of Obstetrics and Gynecology, Cleveland Clinic, Reproductive Research Center, Glickman Urological and Kidney Institute, Cleveland, Ohio 44195, USA
    Fertil Steril 91:1110-8. 2009
    ..To examine the relationship among sperm apoptosis, sperm chromatin status, and DNA ploidy in different sperm fractions...
  17. ncbi request reprint Role of caspases in male infertility
    Tamer M Said
    Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, Glickman Urological Institute and Department of Obstetrics and Gynecology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk A19 1, Cleveland, OH 44195, USA
    Hum Reprod Update 10:39-51. 2004
    ..In this review, we summarize the consequences of caspase activation, aiming to clarify their role in the pathogenesis of male infertility...
  18. ncbi request reprint Role of antioxidants in treatment of male infertility: an overview of the literature
    Ashok Agarwal
    Centre for Advanced Research in Human Reproduction, Infertility, and Sexual Function, Glickman Urological Institute and Dept of Obstetrics and Gynecology, Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk A19 1, Cleveland, OH, USA
    Reprod Biomed Online 8:616-27. 2004
    ..Multicentre, double-blind studies with statistically accepted sample size are still needed to provide conclusive evidence on the benefit of antioxidants as a treatment modality for patients with male infertility...
  19. ncbi request reprint Carnitines and male infertility
    A Agarwal
    Department of Obstetrics and Gynecology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk A19 1, Cleveland, OH 44195, USA
    Reprod Biomed Online 8:376-84. 2004
    ..Additional, well-designed studies are necessary to further validate the use of carnitines in the treatment of patients with male infertility, specifically in men with poor semen quality...
  20. ncbi request reprint Evaluation of nuclear DNA damage in spermatozoa from infertile men with varicocele
    Ramadan A Saleh
    Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, Glickman Urological Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Fertil Steril 80:1431-6. 2003
    ..To examine levels of sperm DNA damage and oxidative stress (OS) in infertile men with varicocele...
  21. ncbi request reprint Role of sperm chromatin abnormalities and DNA damage in male infertility
    A Agarwal
    Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, Glickman Urological Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Hum Reprod Update 9:331-45. 2003
    ..Therefore, screening for sperm DNA damage may provide useful information in cases of male idiopathic infertility and in those men pursuing assisted reproduction. Treatment should include methods for prevention of sperm DNA damage...
  22. ncbi request reprint Magnetic-activated cell sorting before cryopreservation preserves mitochondrial integrity in human spermatozoa
    Sonja Grunewald
    Department of Dermatology Andrology Unit, University of Leipzig, Germany
    Cell Tissue Bank 7:99-104. 2006
    ..MACS using annexin-V microbeads enhances the percentage of spermatozoa with intact transmembrane mitochondrial potential and mitochondrial integrity survival rates following cryopreservation...
  23. pmc Utility of magnetic cell separation as a molecular sperm preparation technique
    Tamer M Said
    Department of Andrology and Reproductive Tissue Banking, Toronto Institute of Reproductive Medicine Repro Med, Toronto, Canada
    J Androl 29:134-42. 2008
    ..The higher sperm quality is represented by an increased oocyte penetration potential and cryosurvival rates. Thus, the selection of nonapoptotic spermatozoa by MACS should be considered to enhance ART success rates...
  24. ncbi request reprint Caspase activation in human spermatozoa in response to physiological and pathological stimuli
    Sonja Grunewald
    Department of Dermatology Andrology Unit, University of Leipzig, Leipzig, Germany
    Fertil Steril 83:1106-12. 2005
    ..To investigate caspase activation in response to a variety of pathological and physiological stimuli in light of the fact that current research offers no clear consensus about caspase activation pathways in spermatozoa...