Mustafa Sahin

Summary

Publications

  1. ncbi request reprint An ectopic parathyroid gland in the left axillary region: case report
    Mustafa Sahin
    Department of General Surgery, Selcuk University, Faculty of Medicine, Konya, Turkey
    Int Surg 89:6-9. 2004
  2. ncbi request reprint [Is interval appendectomy necessary after conservative treatment of appendiceal masses?]
    Ramazan Eryilmaz
    Department of General Surgery 1st, SSK Vakif Gureba Training Hospital, Istanbul, Turkey
    Ulus Travma Acil Cerrahi Derg 10:185-8. 2004
  3. doi request reprint Internal herniation as a major cause of intestinal obstruction
    Ahmet Tekin
    Department of General Surgery, Meram Medical Faculty, University of Selcuk, Konya, Turkey
    Med Princ Pract 17:400-3. 2008
  4. ncbi request reprint The effect of scolicidal agents on liver and biliary tree (experimental study)
    Mustafa Sahin
    Department of Surgery, Vakif Gureba Training Hospital, Istanbul, Turkey
    J Invest Surg 17:323-6. 2004
  5. ncbi request reprint Effects of selective iNOS inhibition in sepsis: evaluation of lung tissue damage and blood gases
    Sami Ceran
    Department of Thoracic Surgery, Selcuk University, Faculty of Medicine, Konya, Turkey
    Int Surg 93:19-24. 2008
  6. ncbi request reprint Clinical and surgical profile and follow up of patients with liver hydatid cyst from an endemic region
    Ahmet Tekin
    Department of General Surgery Meram Medical Faculty, University of Selcuk, Akyokus, Konya, Turkey
    J Gastrointestin Liver Dis 17:33-7. 2008
  7. ncbi request reprint Obesity and obstructive sleep apnea syndrome
    Engin Acioglu
    Department of Otorhinolaryngology, Istanbul Training and Research Hospital, Turkey
    J Otolaryngol Head Neck Surg 39:744-51. 2010
  8. ncbi request reprint Umbilical pilonidal sinus disease: predisposing factors and treatment
    Ramazan Eryilmaz
    Department of General Surgery, Vakif Gureba Training Hospital, E 4 Blok 55, Faith, Istanbul 34250, Turkey
    World J Surg 29:1158-60. 2005
  9. ncbi request reprint Management of lactational breast abscesses
    Ramazan Eryilmaz
    Department of Surgery, Vakif Gureba Training Hospital, Istanbul, Turkey
    Breast 14:375-9. 2005
  10. pmc Severe hypertriglyceridemia-induced pancreatitis during pregnancy
    Alptekin Gursoy
    Faculty of Medicine, Department of Endocrinology and Metabolism, Baskent University, Ankara, Turkey
    J Natl Med Assoc 98:655-7. 2006

Collaborators

Detail Information

Publications62

  1. ncbi request reprint An ectopic parathyroid gland in the left axillary region: case report
    Mustafa Sahin
    Department of General Surgery, Selcuk University, Faculty of Medicine, Konya, Turkey
    Int Surg 89:6-9. 2004
    ..We think the case presented here is the first case with this axillary location. Scintigraphy, alone or combined with other methods, may be used to determine ectopic localizations...
  2. ncbi request reprint [Is interval appendectomy necessary after conservative treatment of appendiceal masses?]
    Ramazan Eryilmaz
    Department of General Surgery 1st, SSK Vakif Gureba Training Hospital, Istanbul, Turkey
    Ulus Travma Acil Cerrahi Derg 10:185-8. 2004
    ..This prospective study was conducted to investigate whether interval appendectomy was necessary after successful conservative treatment of appendiceal masses...
  3. doi request reprint Internal herniation as a major cause of intestinal obstruction
    Ahmet Tekin
    Department of General Surgery, Meram Medical Faculty, University of Selcuk, Konya, Turkey
    Med Princ Pract 17:400-3. 2008
    ..To evaluate internal herniation as a rare cause of intestinal obstruction...
  4. ncbi request reprint The effect of scolicidal agents on liver and biliary tree (experimental study)
    Mustafa Sahin
    Department of Surgery, Vakif Gureba Training Hospital, Istanbul, Turkey
    J Invest Surg 17:323-6. 2004
    ..We suggest that direct injection of scolicidal agents into the cyst should be avoided particulary in case of biliary communication. If this is to be practiced, hypertonic saline should be preferred as a scolicidal agent...
  5. ncbi request reprint Effects of selective iNOS inhibition in sepsis: evaluation of lung tissue damage and blood gases
    Sami Ceran
    Department of Thoracic Surgery, Selcuk University, Faculty of Medicine, Konya, Turkey
    Int Surg 93:19-24. 2008
    ..The levels in the aminoguanidine and aminoguanidine + L-arginine groups were similar to the sham group. Lung tissue damage in the sepsis and L-arginine groups was more severe than the other groups...
  6. ncbi request reprint Clinical and surgical profile and follow up of patients with liver hydatid cyst from an endemic region
    Ahmet Tekin
    Department of General Surgery Meram Medical Faculty, University of Selcuk, Akyokus, Konya, Turkey
    J Gastrointestin Liver Dis 17:33-7. 2008
    ..The aim of this study is to present the changes in the treatment of liver hydatid cyst during the last 20 years in our clinic according to literature data...
  7. ncbi request reprint Obesity and obstructive sleep apnea syndrome
    Engin Acioglu
    Department of Otorhinolaryngology, Istanbul Training and Research Hospital, Turkey
    J Otolaryngol Head Neck Surg 39:744-51. 2010
    ..to investigate the association of sleep apnea severity with insulin resistance, leptin, adipose-fatty acid binding protein (A-FABP) and visfatin levels and to evaluate the confounding role of obesity...
  8. ncbi request reprint Umbilical pilonidal sinus disease: predisposing factors and treatment
    Ramazan Eryilmaz
    Department of General Surgery, Vakif Gureba Training Hospital, E 4 Blok 55, Faith, Istanbul 34250, Turkey
    World J Surg 29:1158-60. 2005
    ..Surgery should be performed in recurrent cases resistant to conservative treatment. The importance of differential diagnosis of umbilical pilonidal sinus from other umbilical pathologies is also emphasized...
  9. ncbi request reprint Management of lactational breast abscesses
    Ramazan Eryilmaz
    Department of Surgery, Vakif Gureba Training Hospital, Istanbul, Turkey
    Breast 14:375-9. 2005
    ..Incision and drainage should be reserved for use in patients with larger abscesses...
  10. pmc Severe hypertriglyceridemia-induced pancreatitis during pregnancy
    Alptekin Gursoy
    Faculty of Medicine, Department of Endocrinology and Metabolism, Baskent University, Ankara, Turkey
    J Natl Med Assoc 98:655-7. 2006
    ..Intravenous insulin is a low-cost and effective alternative treatment in hypertriglyceridemia-induced pancreatitis during pregnancy. To our knowledge, such a high triglyceride level has not previously been reported in pregnancy...
  11. doi request reprint Clinicopathological characteristics of thyroid cancer in patients on dialysis for end-stage renal disease
    Asli Nar Demirer
    Department of Endocrinology and Metabolism, Faculty of Medicine, Baskent University, Ankara, Turkey
    Thyroid 18:45-50. 2008
    ..Our aim was to determine the prevalence and clinicopathological characteristics of thyroid cancers in the dialysis population and to evaluate the potential risk factors...
  12. ncbi request reprint The effects of anti-adhesion materials in preventing postoperative adhesion in abdominal cavity (anti-adhesion materials for postoperative adhesions)
    Mustafa Sahin
    Department of General Surgery, Selcuk University Meram Medical Faculty, Konya, Turkey
    Inflammation 30:244-9. 2007
    ..The purpose of this study was to compare the effects of anti-adhesion materials in postoperative adhesions...
  13. ncbi request reprint Needle-free delivery of lidocaine for reducing the pain associated with the fine-needle aspiration biopsy of thyroid nodules: time-saving and efficacious procedure
    Alptekin Gursoy
    Department of Endocrinology and Metabolism, Baskent University Faculty of Medicine, Ankara, Turkey
    Thyroid 17:317-21. 2007
    ..In this double-blind, placebo-controlled clinical trial, we evaluated the effectiveness of a needle-free injection of lidocaine in achieving satisfactory pain control in patients undergoing FNAB of thyroid nodules...
  14. ncbi request reprint The analgesic efficacy of lidocaine/prilocaine (EMLA) cream during fine-needle aspiration biopsy of thyroid nodules
    Alptekin Gursoy
    Department of Endocrinology and Metabolism, Baskent University Faculty of Medicine, 5 Cadde No 48, 06490 Bahcelievler, Ankara, Turkey
    Clin Endocrinol (Oxf) 66:691-4. 2007
    ..The aim of this study was to determine the analgesic efficacy of EMLA for FNAB-associated pain in patients with NTD...
  15. ncbi request reprint Closure of fascial defect at trocar sites after laparoscopic surgery
    Mustafa Sahin
    Department of Surgery, Vakif Gureba Training Hospital, Istanbul, Turkey
    Minim Invasive Ther Allied Technol 15:317-8. 2006
    ..The aforementioned technique is easy to perform and facilitates the closure of the fascial defect at trocar sites, and there is no extra cost for the procedure...
  16. ncbi request reprint [A case of Rapunzel syndrome]
    Ramazan Eryilmaz
    1st Department of General Surgery, SSK Vakif Gureba Training Hospital, Istanbul, Turkey
    Ulus Travma Acil Cerrahi Derg 10:260-3. 2004
    ..Following removal of the lesion, the antrum was observed with multiple ulcers secondary to extensive pressure. Postoperative period was uneventful. A subsequent psychiatric consultation revealed depressive personality disorder...
  17. ncbi request reprint Which repair in umbilical hernia of adults: primary or mesh?
    Ramazan Eryilmaz
    Department of Surgery, Vakif Gureba Training Hospital, Istanbul, Turkey
    Int Surg 91:258-61. 2006
    ..In conclusion, contrary to the general tendency that small defects can be repaired primarily, polypropylene mesh should be used in all umbilical hernias regardless of the size of the defect...
  18. doi request reprint Gallbladder bed irrigation with bupivacaine improves pulmonary functions after laparoscopic cholecystectomy
    Hunsu Alptekin
    Department of Surgery, Selcuklu Medical Faculty, Selcuk University, 42075, Konya, Turkey
    Langenbecks Arch Surg 395:501-4. 2010
    ..Pulmonary function would be improved by blocking this stimulus after laparoscopic cholecystectomy. This randomized prospective study evaluated this hypothesis in patients who underwent laparoscopic cholecystectomy...
  19. doi request reprint Surgical treatment of complicated pilonidal sinus with a fasciocutaneous V-Y advancement flap
    Ramazan Eryilmaz
    Department of Surgery, Vakif Gureba Training Hospital, Istanbul, Turkey
    Dis Colon Rectum 52:2036-40. 2009
    ..In this study, we investigated the value of fasciocutaneous V-Y advancement flap reconstruction in the treatment of complicated or recurrent sacrococcygeal pilonidal sinus...
  20. ncbi request reprint [The comparison of incision and drainage with skin excision and curettage in the treatment of acute pilonidal abscess]
    Ramazan Eryilmaz
    Vakif Gureba Eğitim Hastanesi l Cerrahi Kliniği, Istanbul, Turkey
    Ulus Travma Acil Cerrahi Derg 9:120-3. 2003
    ..To compare therapeutic values of incision and drainage, with skin excision and curettage in surgical treatment of the patients with acute pilonidal abscess...
  21. ncbi request reprint The role of dura mater and free peritoneal graft in the reinforcement of colon anastomosis
    Ramazan Eryilmaz
    Department of Surgery, Vakif Gureba Training Hospital, Istanbul, Turkey
    J Invest Surg 20:15-21. 2007
    ....
  22. ncbi request reprint Bacterial translocation to kidney in rats with intestinal obstruction and the role of nitric oxide
    Emin Ozbek
    Vakif Gureba Research and Education Hospital, Department of Urology, Fatih Istanbul, Turkey
    Arch Ital Urol Androl 81:56-8. 2009
    ..In this study we aimed to investigate the BT to kidney and the protective effect of nitric oxide (NO) inhibition...
  23. ncbi request reprint Effects of hypertonic saline, HAES and dimethylsulphoxide on free oxygen radicals in haemorrhagic shock oxygen radicals in haemorrhagic shock
    Aysegul Bayir
    Meram Medical Faculty of Selçuk University Emergency Department, Merman University Experimental Medicine and Research Center, 42080 Merman Konya
    Ulus Travma Acil Cerrahi Derg 9:154-9. 2003
    ..The aim of this study was to investigate the effects of antioxidant and resuscitation fluids which were used during haemorrhagic shock on tissue ischemia...
  24. ncbi request reprint [Complicated Meckel's diverticulum]
    Adem Akcakaya
    S S K Vakif Gureba Teaching Hospital, 1st Surgical Clinic, Istanbul, Turkey
    Ulus Travma Acil Cerrahi Derg 9:246-9. 2003
    ..In this study we present our experience in the surgical treatment of complicated Meckel's diverticulum...
  25. pmc Preoperative detection of insulinomas: two case reports
    Mesut Ozkaya
    Department of General Surgery, Sutcu Ymam University Medical Faculty, Kahramanmaras, Turkey
    Cases J 1:362. 2008
    ..abstract:..
  26. doi request reprint Neurofibroma adjacent to the thyroid gland and a thyroid papillary carcinoma in a patient with neurofibromatosis type 1: report of a case
    Yavuz Koksal
    Department of Pediatric Oncology, Selcuk University, Konya 42080, Turkey
    Surg Today 39:884-7. 2009
    ..This report presents a case of a neurofibroma adherent to the thyroid gland with thyroid papillary carcinoma in a 26-year-old woman with NF type 1...
  27. ncbi request reprint The effects of different hernia repair methods on postoperative pain medication and CRP levels
    Celalettin Vatansev
    Department of General Surgery, Faculty of Medicine, University of Selcuk, Akyokus, Konya, Turkey
    Surg Laparosc Endosc Percutan Tech 12:243-6. 2002
    ..In conclusion, TEP mesh hernioplasty is less traumatic and yields less postoperative pain than the Nyhus, Lichtenstein, and Bassini procedures...
  28. ncbi request reprint Determination of operation time in colorectal diseases: preoperative chemotherapy application
    Mustafa Sahin
    Meram Medical Faculty, Selcuk University, Konya, Turkey
    J Surg Res 124:209-15. 2005
    ..Our aim was to determine the time it takes for wound healing to return to normal in cases where patients have undergone preoperative chemotherapy...
  29. ncbi request reprint Surgical treatment of sacrococcygeal pilonidal sinus with the Limberg transposition flap
    Ramazan Eryilmaz
    Department of General Surgery, Vakif Gureba Training Hospital, 34250 Fatih, Istanbul, Turkey
    Surgery 134:745-9. 2003
    ..Pilonidal sinus is a common chronic disease of the sacrococcygeal region. Although many surgical methods have been suggested, an ideal method is still lacking because of high recurrence rates...
  30. ncbi request reprint Effects of gender on the severity of sepsis
    Mehmet Erikoglu
    Department of General Surgery, Meram Medical Faculty, Selcuk University, Akyokus, 42080, Konya, Turkey
    Surg Today 35:467-72. 2005
    ..To investigate the differences between male and female rats and the effects of sex hormones on tissue changes in the lung and liver in a sepsis model...
  31. ncbi request reprint RF-assisted cystectomy and pericystectomy: a new technique in the treatment of liver hydatid disease
    Mustafa Sahin
    Department of General Surgery, Selcuk University Meram Medical Faculty, Konya, Turkey
    Eur Surg Res 38:90-3. 2006
    ..Radiofrequency (RF) energy has been used for ablation and resection of liver tumors. Purpose: To present a new technique for the treatment of liver hydatid cyst disease...
  32. ncbi request reprint Percutaneous treatment of liver hydatid cysts: comparison of direct injection of albendazole and hypertonic saline solution
    Yahya Paksoy
    Department of Radiology, Selcuk University, Meram School of Medicine, Konya, Turkey
    AJR Am J Roentgenol 185:727-34. 2005
    ..The purpose of this study was to compare the effect of intracystic injection of albendazole and hypertonic saline in patients with liver hydatid disease...
  33. doi request reprint Long-term results utilizing the unroofing technique in treating hydatid cysts of the liver
    Ahmet Tekin
    Department of General Surgery, Meram Medical Faculty, University of Selcuk, Akyokus, Konya, Turkey
    Surg Today 38:801-6. 2008
    ..The aim of this study was to present the long-term follow-up results of liver hydatid cysts treated with unroofing, together with a review of the related literature data...
  34. ncbi request reprint Thyroid medullary carcinoma in a teenager with Cowden syndrome
    Yavuz Koksal
    Department of Pediatric Oncology, Selcuk University, Meram Medical Faculty, Konya, Turkey
    Laryngoscope 117:1180-2. 2007
    ..Total thyroidectomy was performed. Histopathologic examination of the specimen revealed thyroid medullary carcinoma. After operation, levels of CEA decreased to normal limits...
  35. doi request reprint Selenium levels in first-degree relatives of diabetic patients
    Mesut Ozkaya
    Department of Endocrinology, Faculty of Medicine, Kahramanmaras Sutcuimam University, Kahramanmaras, Turkey
    Biol Trace Elem Res 128:144-51. 2009
    ..98 vs 0.81 +/- 0.76 mg/dL, p < 0.003; 1.99 +/- 0.88 vs 1.64 +/- 0.74, p < 0.005; 15.0 +/- 7.6 vs 12.9 +/- 5.7 micromol/L, p < 0.049, respectively). Selenium deficiency may contribute to cardiovascular disease risk in FDR...
  36. doi request reprint Association of the G894T polymorphism of the endothelial nitric oxide synthase gene with diabetic foot syndrome foot ulcer, diabetic complications, and comorbid vascular diseases: a Turkish case-control study
    Demet Corapcioglu
    Department of Endocrinology and Metabolic Diseases, Faculty of Medicine, Ankara University, Ankara, Turkey
    Genet Test Mol Biomarkers 14:483-8. 2010
    ....
  37. ncbi request reprint Percutaneous sonographically guided treatment of hydatid cysts in sheep: direct injection of mebendazole and albendazole
    Yahya Paksoy
    Ultra Görüntüleme Merkezi, Konya, Turkey
    J Ultrasound Med 22:797-803. 2003
    ..The purpose of this study was to investigate the scolicidal effect of intracystic injection of benzimidazolic solutions in naturally infected sheep with hydatid disease...
  38. ncbi request reprint Prevention of adhesion formations following repair of abdominal wall defects with prosthetic materials (an experimental study)
    Orhan Alimoglu
    First Department of Surgery, Vakif Gureba Training Hospital, Istanbul, Turkey
    Hepatogastroenterology 50:725-8. 2003
    ..The aim of this study was to compare different modalities in terms of adhesion prevention in a rat model of abdominal wall defect repaired with prosthetic materials...
  39. ncbi request reprint Ultrasound-guided fine-needle aspiration biopsy and ultrasonographic features of infracentimetric nodules in patients with nodular goiter: correlation with pathological findings
    Mustafa Sahin
    Department of Endocrinology and Metabolic Disease, Baskent University, Ankara, Turkey
    Endocr Pathol 17:67-74. 2006
    ..In conclusion, small tumor size does not guarantee a low risk of thyroid cancer, and US-FNAB may be useful tool for diagnosing malignant infracentimetric nodules...
  40. ncbi request reprint Postprandial lipemia as a risk factor for cardiovascular disease in patients with hypothyroidism
    Nedret Tanaci
    Department of Endocrinology and Metabolic Diseases, Baskent University Faculty of Medicine, Turkey
    Endocrine 29:451-6. 2006
    ..In subjects with TSH levels higher than 5 microIU/mL, PPL risk was increased sevenfold. The results of this study show that postprandial triglyceride metabolism is affected in hypothyroidism...
  41. ncbi request reprint Diphenhydramine and hyaluronic acid derivatives reduce adnexal adhesions and prevent tubal obstructions in rats
    Ayse Filiz Avsar
    Department of Obstetrics and Gynecology, Zekai Tahir Burak Maternity Training and Research Hospital, Ankara, Turkey
    Eur J Obstet Gynecol Reprod Biol 106:50-4. 2003
    ..The purpose of this study is to investigate the effects of diphenhydramine-HCl and Na-hyaluronate derivatives on the development of postoperative peritoneal adhesion and tubal obstruction...
  42. ncbi request reprint Timing of cholecystectomy for acute biliary pancreatitis: outcomes of cholecystectomy on first admission and after recurrent biliary pancreatitis
    Orhan Alimoglu
    First Department of Surgery, Vakif Gureba Training Hospital, 34280 Capa, Istanbul, Turkey
    World J Surg 27:256-9. 2003
    ..Waiting to perform cholecystectomy (interval cholecystectomy) may result in recurrent biliary pancreatitis, which may increase morbidity and the length of the hospital stay...
  43. ncbi request reprint Tuberculosis of the breast
    Adem Akcakaya
    Breast J 11:85-6. 2005
  44. ncbi request reprint PPARgamma staining as a surrogate for PAX8/PPARgamma fusion oncogene expression in follicular neoplasms: clinicopathological correlation and histopathological diagnostic value
    Mustafa Sahin
    Department of Medicine, Mayo Clinic and Foundation, 200 First Street SW, Rochester, Minnesota 55905, USA
    J Clin Endocrinol Metab 90:463-8. 2005
    ..g. during intraoperative frozen section). PPARgamma staining also shows an association with favorable prognosis and may have a role in risk stratification...
  45. ncbi request reprint Acute appendicitis during pregnancy
    Ramazan Eryilmaz
    First Department of Surgery, Vakif Gureba Training Hospital, Istanbul, Turkey
    Dig Surg 19:40-4. 2002
    ..To analyze the diagnosis and surgical treatment of acute appendicitis during pregnancy...
  46. ncbi request reprint The PAX8/PPARgamma fusion oncoprotein transforms immortalized human thyrocytes through a mechanism probably involving wild-type PPARgamma inhibition
    J Gregory Powell
    Department of Medicine, Division of Endocrinology, Mayo Clinic, Rochester, MN 55906, USA
    Oncogene 23:3634-41. 2004
    ..Our data suggest that PPFP contributes to malignant transformation during FTC oncogenesis by acting on several cellular pathways, at least some of which are normally regulated by PPARgamma...
  47. ncbi request reprint Prolonged treatment for acute symptomatic refractory status epilepticus: outcome in children
    Mustafa Sahin
    Division of Epilepsy and Clinical Neurophysiology and the Critical Care Neurology Service, Department of Neurology, Children s Hospital, Boston, MA 02115, USA
    Neurology 61:398-401. 2003
    ..The authors therefore studied the long-term outcome in previously normal children who survived prolonged HDST for acute symptomatic RSE. All have intractable epilepsy, and none returned to baseline...
  48. ncbi request reprint Surgery for hyperthyroidism in Down syndrome: case report
    Mustafa Sahin
    Baskent University, Department of Endocrinology and Metabolism, 5th Street, Bahcelievler, Ankara Turkey
    Mt Sinai J Med 73:784-6. 2006
    ..We also review the literature on the treatment options for hyperthyroidism with DS. We conclude that the role of surgery in the treatment of hyperthyroid patients with DS has yet to be defined...
  49. ncbi request reprint Ischemia-reperfusion injury following superior mesenteric artery occlusion and strangulation obstruction
    Adem Akcakaya
    First Department of Surgery, Vakif Gureba Training Hospital, Istanbul, Turkey
    J Surg Res 108:39-43. 2002
    ..Intestinal ischemia-reperfusion injury (IRI) is a serious and common clinical entity resulting in severe tissue injury. This study was designed to compare IRI in superior mesenteric artery (SMA) occlusion and strangulation obstruction (SO)...
  50. ncbi request reprint Increased serum chitotriosidase activity following restoration of euthyroidism in patients with subclinical hypothyroidism
    Muhammed Erdal
    Department of Family Medicine Gulhane School of Medicine, Etlik, Ankara, Turkey
    Intern Med 47:1309-14. 2008
    ..Chitotriosidase activity (ChT) is a new cardiovascular risk marker and is independent of C-reactive protein. The purpose of this study was to determine ChT levels in SH and to examine the effect of levothyroxine replacement on ChT...
  51. ncbi request reprint [The effect of long- or short-arm casting on the stability of reduction and bone mineral density in conservative treatment of Colles' fractures]
    Mustafa Sahin
    Department of Orthopedics and Traumatology 4 Ortopedi ve Travmatoloji Kliniği, Ankara Numune Training and Research Hospital, Ankara, Turkey
    Acta Orthop Traumatol Turc 39:30-4. 2005
    ..We evaluated the effect of long- or short-arm casting on the stability of reduction and bone mineral density (BMD) in the forearm in patients treated conservatively for Colles' fractures (CF)...
  52. pmc Response of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: effects on mTORC1 and Akt signaling lead to improved survival and function
    Lynsey Meikle
    Division of Translational Medicine, Department of Medicine, Brigham and Women s Hospital, Children s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Neurosci 28:5422-32. 2008
    ..Although caution is appropriate, the results suggest the possibility that rapamycin/RAD001 may have benefit in the treatment of TSC brain disease, including infantile spasms...
  53. ncbi request reprint Effects of metformin or rosiglitazone on serum concentrations of homocysteine, folate, and vitamin B12 in patients with type 2 diabetes mellitus
    Mustafa Sahin
    Department of Endocrinology and Metabolic Diseases, Baskent University Faculty of Medicine, Ankara, Turkey
    J Diabetes Complications 21:118-23. 2007
    ..We investigated whether 6 weeks' treatment with metformin or rosiglitazone affects serum concentrations of Hcy, folate, or vitamin B(12) in subjects with newly diagnosed type 2 diabetes compared with controls...
  54. ncbi request reprint Comparison of mechanical bowel obstruction cases of intra-abdominal tumor and non-tumoral origin
    Adem Akcakaya
    First Department of Surgery, Vakif Gureba Training and Research Hospital, Istanbul, Turkey
    World J Surg 30:1295-9. 2006
    ..Mechanical bowel obstruction cases constitute an important place in emergency health care services. In this study, bowel obstructions caused by intra-abdominal tumors were compared with those without tumoral causes...
  55. ncbi request reprint A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival
    Lynsey Meikle
    Division of Translational Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Neurosci 27:5546-58. 2007
    ..This new TSC brain model replicates several features of human TSC brain lesions and implicates an important function of Tsc1/Tsc2 in neuronal development...
  56. ncbi request reprint Three-dimensional MR and axial CT colonography versus conventional colonoscopy for detection of colon pathologies
    Rahime Haykir
    Department of Radiology, Selcuk University Meram Medical Faculty, Konya 42080, Turkey
    World J Gastroenterol 12:2345-50. 2006
    ..To evaluate the sensitivity and specificity of MR colonography (MRC) and CT performance in detecting colon lesions, and to compare their sensitivity and specificity with that of conventional colonoscopy...
  57. ncbi request reprint Comparison of insulin monotherapy and combination therapy with insulin and metformin or insulin and rosiglitazone or insulin and acarbose in type 2 diabetes
    Hamiyet Yilmaz
    Department of Endocrinology and Metabolic Diseases, Baskent University Faculty of Medicine, 5 sokak No 48, 06490 Bahcelievler Ankara, Turkey
    Acta Diabetol 44:187-92. 2007
    ..All groups were comparable in hypoglycemic episodes. No serious adverse event was noted in any group...
  58. doi request reprint Clinical presentation and diagnosis of tuberous sclerosis complex in infancy
    Anita N Datta
    Department of Neurology, Children s Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    J Child Neurol 23:268-73. 2008
    ..Early diagnosis of tuberous sclerosis complex may be essential to the success of future therapies by providing a window of opportunity for their use...
  59. pmc Reinforcement of the suture line with an ePTFE graft attached with histoacryl glue in duodenal trauma
    Oral Saygun
    Department of Surgery, Kirikkale University, School of Medicine, Kirikkale, Turkey
    Can J Surg 49:107-12. 2006
    ..Therefore, we evaluated whether the primary repair site could be reinforced with histoacryl glue (HAG) or HAG with an expanded polytetrafluoroethylene (ePTFE) mesh...
  60. ncbi request reprint Induction and assessment methods used in experimental adhesion studies
    Hakan Ozel
    First Department of Surgery, Ankara Numune Training and Research Hospital, Ankara, Turkey
    Wound Repair Regen 13:358-64. 2005
    ..Extensive use of complex adhesion classification systems should be used to resolve this discordance between experimental studies...
  61. ncbi request reprint The effect of the degree of histologic inflammation on gallbladder perforation during laparoscopic cholecystectomy
    Gurhan Bas
    Department of Surgery, Vakif Gureba Training Hospital, Istanbul, Turkey
    J Laparoendosc Adv Surg Tech A 15:130-4. 2005
    ..Intraoperative gallbladder perforation is a common complication encountered during the surgery. The purpose of this study was to identify the effects of inflammation on gallbladder perforation during LC...
  62. pmc Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis
    Umut Ozcan
    Department of Genetics and Complex Diseases, Harvard School of Public Health, Harvard University, Boston, MA 02115, USA
    Mol Cell 29:541-51. 2008
    ..These results demonstrate ER stress as a critical component of the pathologies associated with dysregulated mTOR activity and offer the possibility to exploit this mechanism for new therapeutic opportunities...