The usefulness of Tc-99m-MDP bone scintigraphy in detection of articular involvement of Behçet's diseaseMehmet Sahin
Department of Internal Medicine, Division of Rheumatology, Suleyman Demirel University, Faculty of Medicine, Isparta, Turkey
Ann Nucl Med 20:649-53. 2006
..Bone scintigraphy is sensitive in the diagnosis of joint involvement allowing earlier diagnosis and showing the presence of articular involvement, especially in SI joints...
Does Fasciola hepatica infection modify the response of acute hepatitis C virus infection to IFN-alpha treatment?Mehmet Sahin
Department of Internal Medicine, Suleyman Demirel University, School of Medicine, Isparta, Turkey
World J Gastroenterol 11:7688-9. 2005
..We report here the case of a male patient who acquired Fasciola hepatica infection after an initial response to IFN-alpha therapy with a favorable outcome...
Protective role of erdosteine on vancomycin-induced oxidative stress in rat liverMehmet Sahin
Department of Internal Medicine, School of Medicine, Suleyman Demirel University, Isparta, Turkey
Mol Cell Biochem 291:155-60. 2006
..01) and catalase (p < 0.001) activities in liver tissue when compared with VCM alone. It can be concluded that erdosteine may prevent VCM-induced oxidative changes in liver by reducing reactive oxygen species...
Antibodies to beta2-glycoprotein-I: relation of anticardiolipin antibodies with clinical and laboratory parameters in patients with systemic lupus erythematosusMehmet Sahin
Department of Internal Medicine, Division of Rheumatology, Faculty of Medicine, Suleyman Demirel University, 32020 Isparta, Turkey
Clin Biochem 40:526-30. 2007
..Thus, we aimed to determine the frequency and clinical importance of aPL isotypes in Turkish patients with SLE...
Hodgkin's lymphoma initially presenting with polymyalgic symptoms: a case reportMehmet Sahin
Division of Rheumatology, Department of Internal Medicine, Suleyman Demirel University School of Medicine, TR 32260 Isparta, Turkey
Mod Rheumatol 17:160-2. 2007
..Hodgkin's lymphoma should be considered in the differential diagnosis of PMR. These musculoskeletal syndromes should alert the physician to possible paraneoplastic manifestations of an evolving neoplasm...
Kaposi's sarcoma complicating rheumatoid arthritis treated with corticosteroid Kaposi's sarcoma and rheumatoid arthritisMehmet Sahin
Department of Internal Medicine, Division of Rhematology, Medical School, Suleyman Demiel University, Tip Fakulesi, Ic Hastaliklari Klinigi, TR-32260, Isparta, Turkey
Saudi Med J 28:1133-4. 2007
Clinical manifestations and antiphosphatidylserine antibodies in patients with systemic lupus erythematosus: is there an association?Mehmet Sahin
Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey
Clin Rheumatol 26:154-60. 2007
..In this study, we aimed to reveal the prevalence and correlation of IgG, IgA, and IgM isotypes of antibodies to cardiolipin (aCL) and antiphosphatidylserine (aPS) with clinical and laboratory manifestations of SLE patients...
Evaluation of joints using Tc 99m-MDP bone scintigraphy in patients with familial Mediterranean fever: should bone scans be used for diagnosis and follow-up?Mustafa Yildiz
Department of Nuclear Medicine, Faculty of Medicine, Suleyman Demirel University, Istiklal Mah Güven Cad 38 8, Isparta, Turkey
Rheumatol Int 26:220-3. 2006
..Thus, we recommend that bone scintigraphy can be used in patients with FMF to determine the presence of arthritis, especially in sacroiliac joints, even asymptomatic...
A fatal case of Behcet's disease with rare complicationsMehmet Sahin
Department of Cardiovascular Surgery, School of Medicine, Suleyman Demirel University, Isparta, Turkey
Saudi Med J 27:1754-7. 2006
..However, he died after the second session of hemodialysis. Patients with BD should be followed up for new developing thrombosis even during an immunosuppressive treatment...
Effects of lycopene and apigenin on human umbilical vein endothelial cells in vitro under angiogenic stimulationMehmet Sahin
Health Sciences Research Centre, Faculty of Medicine, Akdeniz University, Antalya, Turkey
Acta Histochem 114:94-100. 2012
..This study provides indications that apigenin and lycopene, which are considered as chemopreventive agents, to be effective in vitro on endothelial cells and angiogenesis...
Lipid peroxidation and parathyroid hormone influence the cytosolic calcium levels of erythrocytes in peritoneal dialysis patientsEmel Sahin
Department of Central Laboratory, Clinical Biochemistry Unit, Faculty of Medicine, Akdeniz University, 07070 Antalya, Turkey
Clin Lab 57:551-7. 2011
..We also investigated the relationship between parathyroid hormone (PTH) and calcium homeostasis in this study...
Colchicine modulates oxidative stress in serum and leucocytes from remission patients with Family Mediterranean Fever through regulation of Ca²+ release and the antioxidant systemMehmet Sahin
Department of Internal Medicine, Division of Rheumatology, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey
J Membr Biol 240:55-62. 2011
..In conclusion, we observed that colchicine induced protective effects on oxidative stress by modulating vitamin E, β-carotene and Ca²+-release levels in FMF patients with a remission period...
Detection of alveolar epithelial injury by Tc-99m DTPA radioaerosol inhalation lung scan in rheumatoid arthritis patientsBerna Okudan
Nuclear Medicine Department, Suleyman Demirel University, School of Medicine, Isparta, Turkey
Ann Nucl Med 19:455-60. 2005
..006). PI values tended to correlate with FEF25-75, although, this was not statistically significant (p = 0.057). This study shows that no changes occur in alveolar-capillary permeability in RA patients without lung alterations...
Inhibition of angiogenesis by S-adenosylmethionineMehmet Sahin
Health Sciences Research Centre, Faculty of Medicine, Akdeniz University, 07070 Antalya, Turkey
Biochem Biophys Res Commun 408:145-8. 2011
..Besides, we have found SAM can block endothelial cell proliferation and the migration of cells towards growth factors-rich media. In conclusion, our study suggests that SAM may be used against angiogenesis as a natural bio-product...
Asymmetric dimethylarginine and nitric oxide levels as signs of endothelial dysfunction in Behcet's diseaseMehmet Sahin
Department of Internal Medicine, Faculty of Medicine, Suleyman Demirel University, Postakutusu 68 Cunur, Isparta, Turkey
Ann Clin Lab Sci 36:449-54. 2006
..These results are evidence for increased plasma ADMA levels and decreased plasma NO levels as risk factors for cardiovascular events in BD patients. Inhibition of NO synthesis by ADMA may contribute to vascular involvement in BD...
Primary viscocanalostomy versus trabeculectomy for primary open-angle glaucoma: three-year prospective randomized clinical trialIlgaz Sagdic Yalvac
Department of Ophthalmology, Ankara Education and Research Hospital, Ankara, Turkey
J Cataract Refract Surg 30:2050-7. 2004
..To compare the efficacy and safety of viscocanalostomy and trabeculectomy in patients with primary open-angle glaucoma (POAG)...
Hemorrhagic Descemet's membrane detachment after viscocanalostomyIlgaz Sagdic Yalvac
Glaucoma Department, Ankara Research and Training Hospital, Ankara, Turkey
J Cataract Refract Surg 29:1440-2. 2003
..Hemorrhagic detachment of Descemet's membrane can cause visual acuity deterioration and should be recognized as a rare complication of viscocanalostomy...
Assessment of aortic stiffness and ventricular diastolic functions in patients with Behçet's diseaseS Ercan Tunc
Department of Internal Medicine, Division of Rheumatology, Suleyman Demirel University Faculty of Medicine, Istanbul Cad No 33 8, 32200, Isparta, Turkey
Rheumatol Int 25:447-51. 2005
..However, tissue Doppler echocardiography has never been used in any of these studies. Aortic stiffness, a cardiovascular risk factor, may also precede ventricular dysfunction...
KNK437, a benzylidene lactam compound, sensitises prostate cancer cells to the apoptotic effect of hyperthermiaEmel Sahin
Department of Biochemistry, Faculty of Medicine, Akdeniz University, Antalya, Turkey
Int J Hyperthermia 27:63-73. 2011
..We suggest that KNK437 is a useful agent for enhancing the efficiency of hyperthermic therapy which has less toxic side-effects in prostate cancer...
Comparison of neopterin levels in patients with coronary artery ectasia versus patients with obstructive coronary artery diseaseMehmet Sahin
Department of Internal Medicine, Suleyman Demirel University, Isparta, Turkey
South Med J 101:476-9. 2008
..The plasma neopterin levels were investigated in coronary artery ectasia (CAE) patients to investigate the role of inflammation...
DNA methylation or histone modification status in metastasis and angiogenesis-related genes: a new hypothesis on usage of DNMT inhibitors and S-adenosylmethionine for genome stabilityMehmet Sahin
Health Sciences Research Centre, Faculty of Medicine, Akdeniz University, 07070 Antalya, Turkey
Cancer Metastasis Rev 29:655-76. 2010
..This hypothesis has discussed the importance of the usage of DNA methylation inhibitors together with SAM to prevent tumor progression and genome instability or changes resulting in additional diseases...
Bleomycin, etoposide and cisplatin (BEP) combination with concurrent imatinib mesylate (GLEEVEC) in chronic myeloid leukemia (CML) patient with mesenchymal tumorHasan Senol Coskun
Medical Faculty, Department of Medical Oncology, Suleyman Demirel University, Isparta, 32040, Turkey
Med Oncol 25:110-2. 2008
....
Plasma thrombomodulin levels in patients with Behçet's diseaseNursen Duzgun
Ankara University School of Medicine, Department of Internal Medicine, Clinical Immunology and Rheumatology, Ankara, Turkey
Rheumatol Int 23:130-3. 2003
..01, respectively). Plasma TM levels did not show a significant relation with clinical manifestations. Increased plasma TM levels are associated with active disease and may reflect the presence of endothelial cell activation and/or injury...
Cardiotrophin-1 plasma levels are increased in patients with diastolic heart failureAtac Celik
Department of Cardiology, Faculty of Medicine, Gaziosmanpasa University, Tokat, Turkey
Med Sci Monit 18:CR25-31. 2012
..The aim of the study was to determine if plasma CT-1 is associated with diastolic heart failure (DHF) and to investigate the relationship between CT-1 and echocardiographic parameters...
Mitral valve replacement in a patient with idiopathic hypereosinophilic syndrome and pulmonary arterial hypertensionIlker Kiris
Department of Cardiovascular Surgery, Suleyman Demirel University Medical School, Isparta, Turkey
J Card Surg 24:80-2. 2009
..This report describes management of a 25-year-old woman with idiopathic hypereosinophilic syndrome, severe mitral stenosis, and pulmonary arterial hypertension...
Cyclooxygenase-2 in cancer and angiogenesisMehmet Sahin
Department of Biochemistry, Faculty of Medicine, Akdeniz University, Antalya, Turkey
Angiology 60:242-53. 2009
..Cyclooxygenase-2 inhibitors have been used to block angiogenesis and tumor proliferation. In this review, the recent studies related to the role of cyclooxygenase-2 in several cancer types and tumor-induced angiogenesis were compiled...
Paraneoplastic remitting seronegative symmetrical synovitis with pitting edema (RS3PE syndrome): a report of two cases and review of the literatureS Ercan Tunc
Department of Rheumatology, Suleyman Demirel University Medical School, Isparta, Turkey
Rheumatol Int 24:234-7. 2004
..Response to low-dose corticosteroid treatment was delayed in the first patient, but the symptoms were relieved better in the second one...
Effect of chronic restraint stress and alpha-lipoic acid on lipid peroxidation and antioxidant enzyme activities in rat peripheral organsMehmet Sahin
Department of Biochemistry, Akdeniz University Medical School, 07070 Antalya, Turkey
Pharmacol Res 54:247-52. 2006
..These findings also suggest that LA-induced changes in antioxidant enzyme activities in rat peripheral organs may contribute to their versatile effects observed in vivo...
Antinucleosome antibodies and systemic lupus erythematosusNursen Duzgun
Department of Clinical Immunology and Rheumatology, Ankara University Faculty of Medicine, Samanpazari 06100, Ankara, Turkey
Ann N Y Acad Sci 1109:421-8. 2007
..89, P < 0.001). The results of our study have revealed that in SLE patients, antinucleosome antibody could be a useful parameter for the assessment of disease activity or renal involvement...