Detail Information
Publications
Hepatocytes as a tool in drug metabolism, transport and safety evaluations in drug discoveryJasminder Sahi
Life Technologies ADME Tox Division, Durham, NC 27703, USA
Curr Drug Discov Technol 7:188-98. 2010..In this review, we will discuss standard and novel in vitro approaches for using primary hepatocytes to extrapolate clinical hepatic metabolism, transport and toxicity...
Aldehyde oxidase activity and inhibition in hepatocytes and cytosolic fractions from mouse, rat, monkey and humanJasminder Sahi
CELLZDIRECT, 4301 Emperor Blvd, Durham, North Carolina 27703, USA
Drug Metab Lett 2:176-83. 2008..Cryopreserved hepatocytes and cytosolic fractions from animals and humans provide qualitatively similar data within the species...
