- Hepatocytes as a tool in drug metabolism, transport and safety evaluations in drug discoveryJasminder Sahi
Life Technologies ADME Tox Division, Durham, NC 27703, USA
Curr Drug Discov Technol 7:188-98. 2010..In this review, we will discuss standard and novel in vitro approaches for using primary hepatocytes to extrapolate clinical hepatic metabolism, transport and toxicity...
- Aldehyde oxidase activity and inhibition in hepatocytes and cytosolic fractions from mouse, rat, monkey and humanJasminder Sahi
CELLZDIRECT, 4301 Emperor Blvd, Durham, North Carolina 27703, USA
Drug Metab Lett 2:176-83. 2008..Cryopreserved hepatocytes and cytosolic fractions from animals and humans provide qualitatively similar data within the species...