Jasminder Sahi

Summary

Publications

  1. ncbi Hepatocytes as a tool in drug metabolism, transport and safety evaluations in drug discovery
    Jasminder Sahi
    Life Technologies ADME Tox Division, Durham, NC 27703, USA
    Curr Drug Discov Technol 7:188-98. 2010
  2. doi A comprehensive evaluation of metabolic activity and intrinsic clearance in suspensions and monolayer cultures of cryopreserved primary human hepatocytes
    Cornelia M Smith
    ADME TOX Division of Life Technologies, Durham, North Carolina 27703, USA
    J Pharm Sci 101:3989-4002. 2012
  3. ncbi Aldehyde oxidase activity and inhibition in hepatocytes and cytosolic fractions from mouse, rat, monkey and human
    Jasminder Sahi
    CELLZDIRECT, 4301 Emperor Blvd, Durham, North Carolina 27703, USA
    Drug Metab Lett 2:176-83. 2008

Collaborators

  • Edward L LeCluyse
  • Cornelia M Smith
  • Stephen S Ferguson
  • Christina K Nolan
  • Jean B Hatfield
  • Manda A Edwards
  • Todd W Stewart

Detail Information

Publications3

  1. ncbi Hepatocytes as a tool in drug metabolism, transport and safety evaluations in drug discovery
    Jasminder Sahi
    Life Technologies ADME Tox Division, Durham, NC 27703, USA
    Curr Drug Discov Technol 7:188-98. 2010
    ..In this review, we will discuss standard and novel in vitro approaches for using primary hepatocytes to extrapolate clinical hepatic metabolism, transport and toxicity...
  2. doi A comprehensive evaluation of metabolic activity and intrinsic clearance in suspensions and monolayer cultures of cryopreserved primary human hepatocytes
    Cornelia M Smith
    ADME TOX Division of Life Technologies, Durham, North Carolina 27703, USA
    J Pharm Sci 101:3989-4002. 2012
    ....
  3. ncbi Aldehyde oxidase activity and inhibition in hepatocytes and cytosolic fractions from mouse, rat, monkey and human
    Jasminder Sahi
    CELLZDIRECT, 4301 Emperor Blvd, Durham, North Carolina 27703, USA
    Drug Metab Lett 2:176-83. 2008
    ..Cryopreserved hepatocytes and cytosolic fractions from animals and humans provide qualitatively similar data within the species...