Sukamal Saha

Summary

Publications

  1. doi request reprint Aberrant drainage of sentinel lymph nodes in colon cancer and its impact on staging and extent of operation
    Sukamal Saha
    McLaren Flint, 3500 Calkins Road, Flint, MI 48532, USA
    Am J Surg 205:302-5; discussion 305-6. 2013
  2. ncbi request reprint Sentinel lymph node mapping in colorectal cancer--a review
    S Saha
    Department of Surgery, Michigan State University College of Human Medicine, Flint, USA
    Surg Clin North Am 80:1811-9. 2000
  3. ncbi request reprint A multicenter trial of sentinel lymph node mapping in colorectal cancer: prognostic implications for nodal staging and recurrence
    Sukamal Saha
    McLaren Regional Medical Center, Michigan State University, 3500 Calkins Road, Suite A, Flint, MI 48532, USA
    Am J Surg 191:305-10. 2006
  4. ncbi request reprint Ultrastaging of colorectal cancer by sentinel lymph node mapping technique--a multicenter trial
    S Saha
    McLaren Regional Medical Center, Michigan State University, Flint, USA
    Ann Surg Oncol 8:94S-98S. 2001
  5. ncbi request reprint Historical review of lymphatic mapping in gastrointestinal malignancies
    Sukamal Saha
    Departments of Surgery, Michigan State University and McLaren Regional Medical Center, Flint, Michigan, USA
    Ann Surg Oncol 11:245S-9S. 2004
  6. doi request reprint Nodal positivity in breast cancer correlated with the number of lesions detected by magnetic resonance imaging versus mammogram
    Sukamal Saha
    Department of Surgical Oncology, Michigan State University, Regional Medical Imaging, Flint, MI 48532 3685, USA
    Am J Surg 201:390-4; discussion 394-5. 2011
  7. ncbi request reprint Lymphazurin 1% versus 99mTc sulfur colloid for lymphatic mapping in colorectal tumors: a comparative analysis
    Sukamal Saha
    McLaren Regional Medical Center, Michigan State University Department of Surgery, Flint, Michigan 48532, USA
    Ann Surg Oncol 11:21-6. 2004
  8. doi request reprint Comparison of nodal positivity between SLNM vs conventional surgery in colon cancer patients with <12 and ≥12 lymph nodes harvested
    Mehul Soni
    Department of Surgical Oncology, McLaren Regional Medical Center, Flint, MI, USA
    Am J Surg 202:207-13. 2011
  9. ncbi request reprint Sentinel lymph node mapping technique in colon cancer
    Sukamal Saha
    Department of Surgery, Michigan State University, Flint, USA
    Semin Oncol 31:374-81. 2004
  10. ncbi request reprint Comparative analysis of nodal upstaging between colon and rectal cancers by sentinel lymph node mapping: a prospective trial
    Sukamal Saha
    Department of Surgery, Michigan State University, East Lansing, Michigan, USA
    Dis Colon Rectum 47:1767-72. 2004

Collaborators

Detail Information

Publications34

  1. doi request reprint Aberrant drainage of sentinel lymph nodes in colon cancer and its impact on staging and extent of operation
    Sukamal Saha
    McLaren Flint, 3500 Calkins Road, Flint, MI 48532, USA
    Am J Surg 205:302-5; discussion 305-6. 2013
    ..The role of aberrant lymphatic drainage in changing operations for patients undergoing sentinel lymph node mapping in colon cancer has not been described on a large scale...
  2. ncbi request reprint Sentinel lymph node mapping in colorectal cancer--a review
    S Saha
    Department of Surgery, Michigan State University College of Human Medicine, Flint, USA
    Surg Clin North Am 80:1811-9. 2000
    ..This article reviews the in vivo and ex vivo techniques for SLN mapping in colorectal cancer, along with its limitations and pitfalls...
  3. ncbi request reprint A multicenter trial of sentinel lymph node mapping in colorectal cancer: prognostic implications for nodal staging and recurrence
    Sukamal Saha
    McLaren Regional Medical Center, Michigan State University, 3500 Calkins Road, Suite A, Flint, MI 48532, USA
    Am J Surg 191:305-10. 2006
    ..Sentinel lymph node (SLN) mapping (M) for staging in colorectal cancer (CRCa) remains controversial and needs to be validated. This study analyzes results of SLNM at a multi-institutional level for CRCa...
  4. ncbi request reprint Ultrastaging of colorectal cancer by sentinel lymph node mapping technique--a multicenter trial
    S Saha
    McLaren Regional Medical Center, Michigan State University, Flint, USA
    Ann Surg Oncol 8:94S-98S. 2001
    ..These patients may then benefit from adjuvant chemotherapy...
  5. ncbi request reprint Historical review of lymphatic mapping in gastrointestinal malignancies
    Sukamal Saha
    Departments of Surgery, Michigan State University and McLaren Regional Medical Center, Flint, Michigan, USA
    Ann Surg Oncol 11:245S-9S. 2004
    ..Over the past 2 years, research and publications related to gastrointestinal lymphatic mapping have dramatically increased worldwide...
  6. doi request reprint Nodal positivity in breast cancer correlated with the number of lesions detected by magnetic resonance imaging versus mammogram
    Sukamal Saha
    Department of Surgical Oncology, Michigan State University, Regional Medical Imaging, Flint, MI 48532 3685, USA
    Am J Surg 201:390-4; discussion 394-5. 2011
    ..We investigated lymph node metastases rates in patients with multifocal or multicentric disease detected by MRI compared with patients with a single lesion detected by mammography and magnetic resonance imaging...
  7. ncbi request reprint Lymphazurin 1% versus 99mTc sulfur colloid for lymphatic mapping in colorectal tumors: a comparative analysis
    Sukamal Saha
    McLaren Regional Medical Center, Michigan State University Department of Surgery, Flint, Michigan 48532, USA
    Ann Surg Oncol 11:21-6. 2004
    ..The combination of isosulfan blue (Lymphazurin) 1% and 99(m)Tc sulfur colloid (TSC) may improve the feasibility and accuracy of lymphatic mapping for colorectal cancer...
  8. doi request reprint Comparison of nodal positivity between SLNM vs conventional surgery in colon cancer patients with <12 and ≥12 lymph nodes harvested
    Mehul Soni
    Department of Surgical Oncology, McLaren Regional Medical Center, Flint, MI, USA
    Am J Surg 202:207-13. 2011
    ..The aim of this study was to compare nodal positivity between sentinel LN mapping (SLNM) and conventional surgery in patients with <12 and ≥12 LNs harvested...
  9. ncbi request reprint Sentinel lymph node mapping technique in colon cancer
    Sukamal Saha
    Department of Surgery, Michigan State University, Flint, USA
    Semin Oncol 31:374-81. 2004
    ..Those patients who are upstaged can then benefit from adjuvant chemotherapy, which has been shown to improve survival of colon cancer patients with nodal disease by at least 33%...
  10. ncbi request reprint Comparative analysis of nodal upstaging between colon and rectal cancers by sentinel lymph node mapping: a prospective trial
    Sukamal Saha
    Department of Surgery, Michigan State University, East Lansing, Michigan, USA
    Dis Colon Rectum 47:1767-72. 2004
    ..A prospective study was undertaken to identify differences in sentinel lymph node mapping between patients with colon cancer and those with rectal cancer...
  11. doi request reprint A prospective trial comparing 1% lymphazurin vs 1% methylene blue in sentinel lymph node mapping of gastrointestinal tumors
    Mehul Soni
    Department of Surgical Oncology, McLaren Regional Medical Center, Flint, MI, USA
    Ann Surg Oncol 16:2224-30. 2009
    ..M has been evaluated in breast cancer in multiple studies with favorable results. Our study compares L with M in the SLNM of gastrointestinal (GI) tumors...
  12. ncbi request reprint 1% lymphazurin vs 10% fluorescein for sentinel node mapping in colorectal tumors
    Adrian G Dan
    Department of Surgery, Michigan State University, McLaren Regional Medical Center, Flint, USA
    Arch Surg 139:1180-4. 2004
    ..Ten percent fluorescein may be successfully used as an alternative to 1% Lymphazurin (1% isosulfan blue; US Surgical Corp, North Haven, Conn) in sentinel lymph node (SLN) mapping for the accurate staging of colorectal tumors...
  13. doi request reprint Detection and prognostic impact of micrometastasis in colorectal cancer
    Saad Sirop
    Department of Surgical Oncology, McLaren Regional Medical Center, Michigan State University, Flint, Michigan, USA
    J Surg Oncol 103:534-7. 2011
    ..The results of those studies were compared with our pilot study of 109 patients with colon cancer, showing improved prognosis of micrometastasis after being upstaged and treated with chemotherapy when compared with NND...
  14. ncbi request reprint Prognostic impact of micrometastases in colon cancer: interim results of a prospective multicenter trial
    Anton J Bilchik
    Department of Gastrointestinal Oncology, John Wayne Cancer Institute at Saint John s Health Center, Santa Monica, CA 90404, and Michigan State University McLaren Regional Medical Center, Flint, MI, USA
    Ann Surg 246:568-75; discussion 575-7. 2007
    ..6% rate of micrometastases (MM) identified by immunohistochemical staining (IHC) of H&E-negative SNs in CC. We hypothesized that these MM have prognostic importance...
  15. ncbi request reprint Sentinel lymph node mapping in colon and rectal cancer: its impact on staging, limitations, and pitfalls
    Sukamal Saha
    Michigan State University, College of Human Medicine, Flint, Michigan, USA
    Cancer Treat Res 127:105-22. 2005
    ..Finally, we will also discuss the current role as well as the future research directions for SLN mapping in colon and rectal cancer...
  16. doi request reprint Ultrastaging of sentinel lymph nodes (SLNs) vs. non-SLNs in colorectal cancer--do we need both?
    David Wiese
    Department of Surgical Oncology, McLaren Regional Medical Center, Michigan State University, Flint, MI, USA
    Am J Surg 199:354-8; discussion 358. 2010
    ..The aim of this study to analyze whether ultrastaging of initially negative nonsentinel lymph nodes (non-SLNs) would increase nodal positivity in colon cancer and rectal cancer...
  17. doi request reprint Comparative analysis of bone marrow micrometastases with sentinel lymph node status in early-stage breast cancer
    Sukamal Saha
    McLaren Regional Medical Center, Flint, MI, USA
    Ann Surg Oncol 16:276-80. 2009
    ..BMM occur in node-negative pts and may assist in identifying pts at high risk for disease recurrence. Obtaining bone marrow aspirate from two locations resulted in a significant increase in detection of micrometastases...
  18. ncbi request reprint Selective lymph node mapping in colorectal cancer--a prospective study for impact on staging, limitations and pitfalls
    Sukamal Saha
    Michiagan State University College of Human Medicine, Department of Surgery, McLaren Regional Medical Center, Flint, Michigan, USA
    Cancer Treat Res 111:109-16. 2002
  19. ncbi request reprint Association of angiogenesis markers with lymph node metastasis in early colorectal cancer
    Douglas M Iddings
    Department of Surgical Oncology, John Wayne Cancer Institute, 2200 Santa Monica Blvd, Santa Monica, CA 90404, USA
    Arch Surg 142:738-44; discussion 744-5. 2007
    ..We hypothesized that p53 mutations (mp53) are associated with decreased expression of thrombospondin 1 (TSP-1) and that decreased TSP-1 expression is associated with lymph node metastases...
  20. doi request reprint Impact of nodal status and tumor burden in sentinel lymph nodes on the clinical outcomes of cancer patients
    Stanley P L Leong
    Center for Melanoma Research and Treatment, Department of Surgery, California Pacific Medical and Research Institute, San Francisco, California 94115, USA
    J Surg Oncol 103:518-30. 2011
    ....
  21. doi request reprint A prospective study of false-positive diagnosis of micrometastatic cells in the sentinel lymph nodes in colorectal cancer
    D Wiese
    Department of Pathology, Michigan State University, McLaren Regional Medical Center, Flint, MI, USA
    Ann Surg Oncol 16:2166-9. 2009
    ..Our prospective study evaluated whether colorectal mapping procedures alone caused false positives...
  22. ncbi request reprint Technical details of sentinel lymph node mapping in colorectal cancer and its impact on staging
    S Saha
    Department of Anatomy, Michigan State University, McLaren Regional Medical Center, Flint, USA
    Ann Surg Oncol 7:120-4. 2000
    ..The purpose of this study was to see if SLN mapping technique could be used to identify SLNs in colorectal cancer and to assess its impact on pathological staging and treatment...
  23. doi request reprint Impact of immediate versus delayed axillary node dissection on surgical outcomes in breast cancer patients with positive sentinel nodes: results from American College of Surgeons Oncology Group Trials Z0010 and Z0011
    John A Olson
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Oncol 26:3530-5. 2008
    ..The impact of the timing of cALND on pathologic results and complications in these patients has not been examined...
  24. ncbi request reprint A phosphatase associated with metastasis of colorectal cancer
    S Saha
    Howard Hughes Medical Institute, The Oncology Center, Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA
    Science 294:1343-6. 2001
    ..3. These data suggest that the PRL-3 gene is important for colorectal cancer metastasis and provide a new therapeutic target for these intractable lesions...
  25. ncbi request reprint Prospective multicenter trial of staging adequacy in colon cancer: preliminary results
    Anton J Bilchik
    John Wayne Cancer Institute and Saint Johns Health Center, Santa Monica, CA 90404, USA
    Arch Surg 141:527-33; discussion 533-4. 2006
    ..A 25% recurrence rate in patients with node-negative CRC suggests that current staging practices are inadequate. Focused analysis of the sentinel node (SN) by multiple sectioning and immunohistochemistry improves staging accuracy...
  26. doi request reprint Novel intraoperative molecular test for sentinel lymph node metastases in patients with early-stage breast cancer
    Thomas B Julian
    Allegheny Breast Care Center, Allegheny General Hospital, 320 E North Ave, Pittsburgh, PA 15212, USA
    J Clin Oncol 26:3338-45. 2008
    ..We present the results from a large, prospective evaluation of the first rapid molecular SLN test, the Breast Lymph Node (BLN) Assay...
  27. ncbi request reprint Sentinel node for gastrointestinal malignancies
    Yuko Kitagawa
    Department of Surgery, Keio University, School of Medicine, 35 Shinanomachi, Shinjuku ku, Tokyo 160 8582, Japan
    Surg Oncol Clin N Am 16:71-80. 2007
    ..A combination of SN mapping and endoscopic surgery will contribute to the improvement in quality of life after surgical treatment of GI cancer...
  28. ncbi request reprint The use of molecular profiling of early colorectal cancer to predict micrometastases
    Anton J Bilchik
    Department of Molecular Oncology, John Wayne Cancer Institute, 2200 Santa Monica Blvd, Santa Monica, CA 90404, USA
    Arch Surg 137:1377-83. 2002
    ..Lymphatic mapping followed by focused analysis of the sentinel node is highly accurate in identifying micrometastases...
  29. ncbi request reprint Sentinel lymph node mapping with GI cancer
    Takashi Aikou
    Department of Surgical Oncology and Digestive Surgery, Kagoshima University, Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    Cancer Metastasis Rev 25:269-77. 2006
    ..Although more evidence from large-scale multicenter clinical trials is required, SLN mapping may be very useful for individualizing multi-modal treatment for esophageal cancer and might be widely acceptable even for GI cancer...
  30. ncbi request reprint Peptide nucleic acid clamp PCR: a novel K-ras mutation detection assay for colorectal cancer micrometastases in lymph nodes
    Bret Taback
    Department of Molecular Oncology, John Wayne Cancer Institute, Saint John s Health Center, Santa Monica, CA 90404, USA
    Int J Cancer 111:409-14. 2004
    ..This study demonstrates the utility, specificity and sensitivity of PNA clamp PCR assay in identifying occult micrometastases in the SLN of CRC patients by single-base mutation analysis...
  31. ncbi request reprint c-MET expression level in primary colon cancer: a predictor of tumor invasion and lymph node metastases
    Hiroya Takeuchi
    Department of Molecular Oncology, John Wayne Cancer Institute, Santa Monica, California 90404, USA
    Clin Cancer Res 9:1480-8. 2003
    ..We hypothesized that overexpression of c-MET and/or VEGF-C mRNA in primary colorectal cancer (CRC) can predict tumor invasion and regional metastasis...
  32. ncbi request reprint Scientific Impact Recognition Award. Sentinel node staging for breast cancer: intraoperative molecular pathology overcomes conventional histologic sampling errors
    Peter Blumencranz
    Breast Health Services, Morton Plant Mease Health Care, 303 Pinellas St, Ste 310, Clearwater, FL 33756, USA
    Am J Surg 194:426-32. 2007
    ..A new intraoperative molecular assay (GeneSearch BLN Assay; Veridex, LLC, Warren, NJ) was evaluated to determine its efficiency in identifying significant sentinel lymph node metastases (>.2 mm)...
  33. ncbi request reprint Current status and future clinical applications of lymphatic mapping in gastrointestinal cancer
    Yuko Kitagawa
    Department of Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku ku, Tokyo 160 8582, Japan
    J Gastroenterol 42:927-31. 2007
  34. ncbi request reprint Comparative analysis of mesenteric and peripheral blood circulating tumor DNA in colorectal cancer patients
    Bret Taback
    Department of Molecular Oncology, John Wayne Cancer Institute, 2200 Santa Monica Blvd, Santa Monica, CA 90404, USA
    Ann N Y Acad Sci 1075:197-203. 2006
    ..The findings provide important evidence supporting the origin of tumor-associated DNA in circulation, which merits consideration when devising blood-based nucleic acid assays for the assessment of CRC...