Umar Sadat

Summary

Publications

  1. ncbi request reprint Carotid artery stiffness in patients with symptomatic carotid artery disease with contralateral asymptomatic carotid artery disease and in patients with bilateral asymptomatic carotid artery disease: a cine phase-contrast carotid MR study
    Umar Sadat
    University Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK Electronic address
    J Stroke Cerebrovasc Dis 23:743-8. 2014
  2. doi request reprint Does ascorbic acid protect against contrast-induced acute kidney injury in patients undergoing coronary angiography: a systematic review with meta-analysis of randomized, controlled trials
    Umar Sadat
    Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom Electronic address
    J Am Coll Cardiol 62:2167-75. 2013
  3. doi request reprint Sequential imaging of asymptomatic carotid atheroma using ultrasmall superparamagnetic iron oxide-enhanced magnetic resonance imaging: a feasibility study
    Umar Sadat
    Department of Radiology, Cambridge University Hospitals National Health Service Foundation Trust, Cambridge, United Kingdom Department of Surgery, Cambridge University Hospitals National Health Service Foundation Trust, Cambridge, United Kingdom Electronic address
    J Stroke Cerebrovasc Dis 22:e271-6. 2013
  4. ncbi request reprint Effect of low-and high-dose atorvastatin on carotid artery distensibility using carotid magnetic resonance imaging -a post-hoc sub group analysis of ATHEROMA (Atorvastatin Therapy: Effects On Reduction Of Macrophage Activity) Study
    Umar Sadat
    University Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
    J Atheroscler Thromb 20:46-56. 2013
  5. doi request reprint Endovascular management of an arteriovenous fistula and concomitant pseudoaneurysm in an intravenous drug abuser
    Umar Sadat
    Cambridge Vascular Unit, Addenbrooke s Hospital, Cambridge, UK
    Vasc Endovascular Surg 42:293-5. 2008
  6. ncbi request reprint Carotid artery stenosis: does the world wide web provide sufficient information to these patients?
    Umar Sadat
    Addenbrooke s Hospital, Cambridge, UK
    Vascular 16:91-4. 2008
  7. doi request reprint Surgical complications in a hemophilia patient with factor VIII inhibitor and their endovascular management
    Umar Sadat
    Cambridge Vascular Unit, Addenbrooke s Hospital, Cambridge, United Kingdom
    Vasc Endovascular Surg 42:168-72. 2008
  8. ncbi request reprint Endovascular management of pseudoaneurysms following lower limb orthopedic surgery
    Umar Sadat
    Vascular Imaging, Addenbrooke s Hospital, NHS Foundation Trust, Cambridge University Hospitals, Cambridge, CB2 2QQ, England
    Am J Orthop (Belle Mead NJ) 37:E99-E102. 2008
  9. doi request reprint Cardioprotection by ischemic postconditioning during surgical procedures
    Umar Sadat
    Clinical Research Associate Vascular Imaging, Cambridge Vascular Unit, Box 201, Department of Surgery, Addenbrooke s Hospital, Cambridge, CB2 2QQ, UK
    Expert Rev Cardiovasc Ther 6:999-1006. 2008
  10. ncbi request reprint Impact of the type of anesthesia on outcome after elective endovascular aortic aneurysm repair: literature review
    Umar Sadat
    Cambridge Vascular Unit, Addenbrooke s Hospital, and University Department of Radiology, Cambridge, UK
    Vascular 16:340-5. 2008

Detail Information

Publications80

  1. ncbi request reprint Carotid artery stiffness in patients with symptomatic carotid artery disease with contralateral asymptomatic carotid artery disease and in patients with bilateral asymptomatic carotid artery disease: a cine phase-contrast carotid MR study
    Umar Sadat
    University Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK Electronic address
    J Stroke Cerebrovasc Dis 23:743-8. 2014
    ..We also investigate the distensibility of bilaterally asymptomatic atherosclerotic carotid arteries using cine phase-contrast carotid magnetic resonance (MR) imaging...
  2. doi request reprint Does ascorbic acid protect against contrast-induced acute kidney injury in patients undergoing coronary angiography: a systematic review with meta-analysis of randomized, controlled trials
    Umar Sadat
    Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom Electronic address
    J Am Coll Cardiol 62:2167-75. 2013
    ....
  3. doi request reprint Sequential imaging of asymptomatic carotid atheroma using ultrasmall superparamagnetic iron oxide-enhanced magnetic resonance imaging: a feasibility study
    Umar Sadat
    Department of Radiology, Cambridge University Hospitals National Health Service Foundation Trust, Cambridge, United Kingdom Department of Surgery, Cambridge University Hospitals National Health Service Foundation Trust, Cambridge, United Kingdom Electronic address
    J Stroke Cerebrovasc Dis 22:e271-6. 2013
    ..The purpose of this study was to assess the feasibility of performing sequential USPIO studies over a 1-year period...
  4. ncbi request reprint Effect of low-and high-dose atorvastatin on carotid artery distensibility using carotid magnetic resonance imaging -a post-hoc sub group analysis of ATHEROMA (Atorvastatin Therapy: Effects On Reduction Of Macrophage Activity) Study
    Umar Sadat
    University Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
    J Atheroscler Thromb 20:46-56. 2013
    ..To assess the effect of low-(10 mg) or high-(80 mg) dose atorvastatin on carotid artery distensibility in patients with asymptomatic carotid artery disease using carotid magnetic resonance imaging...
  5. doi request reprint Endovascular management of an arteriovenous fistula and concomitant pseudoaneurysm in an intravenous drug abuser
    Umar Sadat
    Cambridge Vascular Unit, Addenbrooke s Hospital, Cambridge, UK
    Vasc Endovascular Surg 42:293-5. 2008
    ..An interesting case of an intravenous drug abuser who had endovascular management of an arteriovenous fistula and concomitant pseudoaneurysm, resulting from recurrent puncture of the femoral artery is reported in this study...
  6. ncbi request reprint Carotid artery stenosis: does the world wide web provide sufficient information to these patients?
    Umar Sadat
    Addenbrooke s Hospital, Cambridge, UK
    Vascular 16:91-4. 2008
    ..Available scoring systems provide a good means of assessment. However, significant improvement is required to enhance the overall quality of health-related Web sites...
  7. doi request reprint Surgical complications in a hemophilia patient with factor VIII inhibitor and their endovascular management
    Umar Sadat
    Cambridge Vascular Unit, Addenbrooke s Hospital, Cambridge, United Kingdom
    Vasc Endovascular Surg 42:168-72. 2008
    ..The treatment of unusual metachronous ruptured aneurysms in a patient with hemophilia A with factor VIII inhibitor is presented, and the outcomes of endovascular and open operations are discussed...
  8. ncbi request reprint Endovascular management of pseudoaneurysms following lower limb orthopedic surgery
    Umar Sadat
    Vascular Imaging, Addenbrooke s Hospital, NHS Foundation Trust, Cambridge University Hospitals, Cambridge, CB2 2QQ, England
    Am J Orthop (Belle Mead NJ) 37:E99-E102. 2008
  9. doi request reprint Cardioprotection by ischemic postconditioning during surgical procedures
    Umar Sadat
    Clinical Research Associate Vascular Imaging, Cambridge Vascular Unit, Box 201, Department of Surgery, Addenbrooke s Hospital, Cambridge, CB2 2QQ, UK
    Expert Rev Cardiovasc Ther 6:999-1006. 2008
    ..We present a literature review of published animal and human studies on ischemic postconditioning, focusing on the advances made in understanding this phenomenon since its inception and the relevant clinical applications...
  10. ncbi request reprint Impact of the type of anesthesia on outcome after elective endovascular aortic aneurysm repair: literature review
    Umar Sadat
    Cambridge Vascular Unit, Addenbrooke s Hospital, and University Department of Radiology, Cambridge, UK
    Vascular 16:340-5. 2008
    ..This review suggests that locoregional anesthesia can improve postoperative outcomes following EVAR by reducing hospital stay, ICU stay, mortality, and morbidity, although other factors may also have some influence...
  11. doi request reprint Endovascular stenting of large popliteal artery aneurysm is feasible!
    U Sadat
    Cambridge Vascular Unit, University Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
    Adv Med Sci 53:335-7. 2008
    ..This is because of the non-availability of long term data about graft patency rates...
  12. doi request reprint Noninvasive imaging of atheromatous carotid plaques
    Umar Sadat
    Department of Radiology, Addenbrooke s Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
    Nat Clin Pract Cardiovasc Med 6:200-9. 2009
    ..In this Review, we focus on the various noninvasive imaging techniques that are being used for morphological and functional assessment of carotid atheromatous plaques in the clinical setting...
  13. doi request reprint Signaling pathways of cardioprotective ischemic preconditioning
    Umar Sadat
    Addenbrooke s Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
    Int J Surg 7:490-8. 2009
    ..During the last 20 years, since the appearance of the first publication on ischemic preconditioning (IP), our knowledge of this phenomenon has increased exponentially...
  14. doi request reprint Utility of high resolution MR imaging to assess carotid plaque morphology: a comparison of acute symptomatic, recently symptomatic and asymptomatic patients with carotid artery disease
    Umar Sadat
    University Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
    Atherosclerosis 207:434-9. 2009
    ....
  15. ncbi request reprint CD36 modulation in the subintimal trapping and LDL-mediated migration of macrophages
    Umar Sadat
    Fellow for Medical Research Council and Royal College of Surgeons of England, Box 201, Level 6, Regional Vascular Unit, Addenbrooke s Hospital, Cambridge, CB2 0QQ, UK
    Expert Rev Cardiovasc Ther 7:587-90. 2009
    ..This may have significant clinical implications since, by blocking this process, reversal of the atherosclerotic process may be possible...
  16. doi request reprint Contrast-induced nephropathy: do statins offer protection?
    Umar Sadat
    Cambridge Vascular Unit, Addenbrooke s Hospital, Cambridge, UK
    Curr Opin Cardiol 26:334-7. 2011
    ..Various clinical studies have been reported investigating the nephroprotective role of statins. In this article, we review relevant clinical studies reported in 2010...
  17. pmc Emergency endovascular management of peripheral artery aneurysms and pseudoaneurysms - a review
    Umar Sadat
    Cambridge Vascular Unit, Cambridge University Hospitals NHS Foundation Trust, UK
    World J Emerg Surg 3:22. 2008
    ..Though long term data about graft patency rates is not yet available, the endovascular approach appears to be a useful minimally invasive technique in situations where open repair is either difficult or not feasible...
  18. pmc Mediastinal extension of a complicated pancreatic pseudocyst; a case report and literature review
    Umar Sadat
    Department of Surgery, Addenbrooke s Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
    J Med Case Reports 1:12. 2007
    ..Mediastinal pancreatic pseudocyst is a rare complication of acute or chronic pancreatitis...
  19. pmc Superior epigastric artery pseudoaneurysm--a rare complication of chest drain insertion in coronary artery bypass grafting
    Umar Sadat
    Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
    J Cardiothorac Surg 2:21. 2007
    ..Although chest drain insertion during coronary artery bypass grafting is a fairly standard procedure, however it may result in extremely rare complications...
  20. ncbi request reprint Peripheral arterial ischemia by a primary lung tumour invading left atrium
    Umar Sadat
    Cambridge Vascular Unit, Addenbrooke s Hospital NHS Foundation Trust, Cambridge, UK
    Lung Cancer 57:237-9. 2007
    ..Peripheral arterial embolism from a malignant tumour is an uncommon manifestation of a neoplasm. Here, we present a case of acute upper limb ischemia due to an embolus originating from primary lung malignancy invading the left atrium...
  21. pmc Peroneal artery pseudoaneurysm--a case report and literature review
    Umar Sadat
    Cambridge Vascular Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
    BMC Surg 7:4. 2007
    ..Aneurysms of the peroneal artery are infrequent and consist mainly of pseudoaneurysms...
  22. ncbi request reprint Splenic artery aneurysms in pregnancy--a systematic review
    Umar Sadat
    Cambridge Vascular Unit, Box 201, Addenbrooke s Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 2QQ, UK
    Int J Surg 6:261-5. 2008
    ..This systematic review provides up-to-date information about the management of splenic artery aneurysms in pregnancy...
  23. pmc Angioleiomyoma of the small intestine - a rare cause of gastrointestinal bleeding
    Umar Sadat
    Cambridge Vascular Unit, Addenbrooke s Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
    World J Surg Oncol 5:129. 2007
    ..Benign tumors are a rare cause of gastrointestinal hemorrhage of which angioleiomyomas constitute a very small minority. They have been reported in literature to present with volvulus, bleeding or intussusceptions...
  24. doi request reprint Endovascular vs open repair of acute abdominal aortic aneurysms--a systematic review and meta-analysis
    Umar Sadat
    Cambridge Vascular Unit, Addenbrooke s Hospital, Cambridge University Hospitals, Cambridge, United Kingdom
    J Vasc Surg 48:227-36. 2008
    ..To compare the results of emergency open repair of acute (ruptured or symptomatic intact) abdominal aortic aneurysms with that of endovascular repair...
  25. ncbi request reprint Efficacy of TNP on lower limb wounds: a meta-analysis
    U Sadat
    CambridgeVascular Unit, Addenbrooke s Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
    J Wound Care 17:45-8. 2008
    ..This meta-analysis of the three RCTs that have compared topical negative pressure with conventional treatment in patients with lower limb ulcers found that it significantly reduced healing times and increased the number of healed wounds...
  26. doi request reprint Remote ischemic preconditioning for renal and cardiac protection during endovascular aneurysm repair: a randomized controlled trial
    Stewart R Walsh
    Cambridge Vascular Unit, Addenbrooke s Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
    J Endovasc Ther 16:680-9. 2009
    ..To report a randomized clinical trial designed to determine if remote ischemic preconditioning (IP) has the ability to reduce renal and cardiac damage following endovascular aneurysm repair (EVAR)...
  27. doi request reprint Endovascular stenting versus open surgery for thoracic aortic disease: systematic review and meta-analysis of perioperative results
    Stewart R Walsh
    Cambridge Vascular Unit, Cambridge University Hospitals, NHS Foundation Trust, Cambridge, United Kingdom
    J Vasc Surg 47:1094-1098. 2008
    ..A number of comparative series have been published but, to date, there has been no meta-analysis comparing outcomes following stenting as opposed to open surgery...
  28. doi request reprint Remote ischemic preconditioning for renal protection during elective open infrarenal abdominal aortic aneurysm repair: randomized controlled trial
    Stewart R Walsh
    Cambridge Vascular Unit, Addenbrooke s Hospital, Cambridge University Hospitals NHS Foundation Trust, United Kingdom
    Vasc Endovascular Surg 44:334-40. 2010
    ..This trial could not confirm that remote IP reduces renal injury following elective open aneurysm surgery...
  29. doi request reprint Treating the thoracic aorta in Marfan syndrome: surgery or TEVAR?
    David G Cooper
    Cambridge University Hospitals NHS Trust, Addenbrooke s Hospital, Cambridge, UK
    J Endovasc Ther 16:60-70. 2009
    ..Reoperation is, however, common in MFS, and minimally invasive techniques may provide a bridging role or alternative solution when revisiting the hostile surgical field...
  30. doi request reprint Impact of plaque haemorrhage and its age on structural stresses in atherosclerotic plaques of patients with carotid artery disease: an MR imaging-based finite element simulation study
    Umar Sadat
    University Department of Radiology, University of Cambridge, Addenbrooke s Hospital, Box 218, Level 5, Hills Road, Cambridge CB2 0QQ, UK
    Int J Cardiovasc Imaging 27:397-402. 2011
    ..Plaque component-dependent stress analysis has the potential of identifying the critical nature of various plaque components...
  31. ncbi request reprint Normalized wall index specific and MRI-based stress analysis of atherosclerotic carotid plaques: a study comparing acutely symptomatic and asymptomatic patients
    Chengcheng Zhu
    University Department of Radiology, University of Cambridge, Cambridge, UK
    Circ J 74:2360-4. 2010
    ..Biomechanical stresses play an important role in determining plaque stability. Quantification of these simulated stresses can be potentially used to assess plaque vulnerability and differentiate different patient groups...
  32. pmc Intraplaque stretch in carotid atherosclerotic plaque--an effective biomechanical predictor for subsequent cerebrovascular ischemic events
    Zhongzhao Teng
    University Department of Radiology, University of Cambridge, Cambridge, United Kingdom
    PLoS ONE 8:e61522. 2013
    ..Stretch is a mechanical parameter, which has been proposed previously to affect the biological activities in different tissues. This study explored its utility in determining plaque vulnerability...
  33. doi request reprint Cost-effectiveness analysis of endovascular versus open surgical repair of acute abdominal aortic aneurysms based on worldwide experience
    Paul D Hayes
    1 Cambridge Vascular Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
    J Endovasc Ther 17:174-82. 2010
    ..To present an economic evaluation of endovascular versus open surgical repair of ruptured abdominal aortic aneurysms (AAA)...
  34. doi request reprint Comparison of the endurant bifurcated endograft vs. aortouni-iliac stent-grafting in patients with abdominal aortic aneurysms: experience from the ENGAGE registry
    Tjun Tang
    Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
    J Endovasc Ther 20:172-81. 2013
    ..To compare the 1-year outcomes after repair of abdominal aortic aneurysms (AAA) with the bifurcated vs. aortouni-iliac (AUI) configuration of the Endurant stent-graft...
  35. pmc Characterization of healing following atherosclerotic carotid plaque rupture in acutely symptomatic patients: an exploratory study using in vivo cardiovascular magnetic resonance
    Zhongzhao Teng
    University Department of Radiology, University of Cambridge, UK
    J Cardiovasc Magn Reson 13:64. 2011
    ..This study aims to characterize the healing process of ruptured FC by assessing the lumen conditions, quantified by the lumen curvature and roughness, using in vivo carotid cardiovascular magnetic resonance (CMR)...
  36. doi request reprint The future of EVAR in the management of ruptured AAAs
    Stewart R Walsh
    Cambridge Vascular Unit, Addenbrooke s Hospital, Cambridge, UK
    J Endovasc Ther 16:I127-33. 2009
    ..In the next few years, a number of large randomized clinical trials will clarify its role. Issues regarding anatomical suitability, techniques, perioperative care, and service provision need to be addressed in order to optimize outcomes...
  37. doi request reprint Atrial fibrillation following elective open abdominal aortic aneurysm repair
    Ayesha Noorani
    Cambridge Vascular Research Unit, Cambridge University Hospitals NHS Foundation Trust, Vascular Surgery, Addenbrooke s Hospital, Cambridge, United Kingdom
    Int J Surg 7:24-7. 2009
    ..We conducted a retrospective study to determine the incidence and clinical associations of atrial fibrillation following open elective abdominal aortic aneurysm repair as well as its effect on prognosis...
  38. doi request reprint Comparison of aortomonoiliac endovascular aneurysm repair versus a bifurcated stent-graft: analysis of perioperative morbidity and mortality
    Ayesha Noorani
    Cambridge Vascular Unit, Addenbrooke s Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
    J Endovasc Ther 16:295-301. 2009
    ..To compare the perioperative morbidity and mortality following endovascular aneurysm repair (EVAR) with a bifurcated stent-graft versus an aortomonoiliac stent-graft combined with a femorofemoral crossover graft...
  39. ncbi request reprint Utility of magnetic resonance imaging-based finite element analysis for the biomechanical stress analysis of hemorrhagic and non-hemorrhagic carotid plaques
    Umar Sadat
    University Department of Radiology, University of Cambridge, Cambridge Vascular Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK
    Circ J 75:884-9. 2011
    ..The purpose of the present study was to use finite element analysis (FEA) to compare the stress profiles of hemorrhagic and non-hemorrhagic profiles...
  40. pmc In vivo MRI-based simulation of fatigue process: a possible trigger for human carotid atherosclerotic plaque rupture
    Yuan Huang
    University Department of Radiology, University of Cambridge, Level 5, Box 218, Hills Road, Addenbrooke s Hospital, Cambridge CB2 0QQ, UK
    Biomed Eng Online 12:36. 2013
    ..In this study, we investigate the fatigue process in human carotid plaques using in vivo carotid magnetic resonance (MR) imaging...
  41. doi request reprint A meta-analysis of minimally invasive versus traditional open vein harvest technique for coronary artery bypass graft surgery
    Sheraz R Markar
    Department of Cardiothoracic Surgery, Papworth Hospital, Papworth Everard, Cambridge, UK
    Interact Cardiovasc Thorac Surg 10:266-70. 2010
    ..However, further studies are required to look at long-term graft patency following minimally invasive vein harvest as this remains a major concern...
  42. doi request reprint Does oral N-acetylcysteine reduce contrast-induced renal injury in patients with peripheral arterial disease undergoing peripheral angiography? A randomized-controlled study
    Umar Sadat
    Cambridge Vascular Unit, Addenbrooke s Hospital, Cambridge, UK
    Angiology 62:225-30. 2011
    ..33). Equivocal changes in RBP and ACR levels by both treatments seem to indicate that either is equally effective in affording renal protection...
  43. doi request reprint Efficacy of closed suction drainage in lower limb arterial surgery: a meta-analysis of published clinical trials
    Alan Karthikesalingam
    Cambridge Vascular Unit, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge, United Kingdom
    Vasc Endovascular Surg 42:243-8. 2008
    ..Accordingly, a systematic review and meta-analysis of the current evidence base for closed suction drainage following surgical lower limb revascularization was undertaken...
  44. pmc Critical mechanical conditions around neovessels in carotid atherosclerotic plaque may promote intraplaque hemorrhage
    Zhongzhao Teng
    University Department of Radiology, University of Cambridge, UK
    Atherosclerosis 223:321-6. 2012
    ..Local mechanical environments around neovessels and their relevant pathophysiologic significance have not yet been examined...
  45. doi request reprint Remote ischemic preconditioning for cerebral and cardiac protection during carotid endarterectomy: results from a pilot randomized clinical trial
    Stewart R Walsh
    Cambridge Vascular Unit, Addenbrooke s Hospital, Cambridge, United Kingdom
    Vasc Endovascular Surg 44:434-9. 2010
    ..97). There were no adverse events related to the preconditioning protocol. Remote ischemic preconditioning appears safe in patients with CEA. Large-scale trials are required to determine whether RIPC confers clinical benefits...
  46. doi request reprint Remote ischemic preconditioning will reduce graft-related events after surgical infrainguinal revascularization: evidence-based surgery hypothesis
    Stewart R Walsh
    Addenbrooke s Hospital, Cambridge, UK
    Surgery 148:1020-1. 2010
    ..So, remote ischemic preconditioning will decrease graft-related complications after surgical infrainguinal revascularization...
  47. doi request reprint Lumen irregularity dominates the relationship between mechanical stress condition, fibrous-cap thickness, and lumen curvature in carotid atherosclerotic plaque
    Zhongzhao Teng
    Department of Radiology, University of Cambridge, Cambridge CB20QQ, UK
    J Biomech Eng 133:034501. 2011
    ..Using lumen irregularity as a method of identifying vulnerable plaque sites by referring to the lumen shape is a novel and simple method, which can be used for mechanics-based plaque vulnerability assessment...
  48. doi request reprint Suprarenal endograft fixation and medium-term renal function: systematic review and meta-analysis
    Stewart R Walsh
    Cambridge Vascular Unit, Cambridge University Hospitals NHS Trust, Cambridge, United Kingdom
    J Vasc Surg 47:1364-1370. 2008
    ..A recent meta-analysis demonstrated that renal infarction is more common with suprarenal fixation, but the effect on renal function remains unclear...
  49. doi request reprint Finite element analysis of vulnerable atherosclerotic plaques: a comparison of mechanical stresses within carotid plaques of acute and recently symptomatic patients with carotid artery disease
    Umar Sadat
    University Department of Radiology, Addenbrooke s Hospital, University of Cambridge, Cambridge CB2 0QQ, UK
    J Neurol Neurosurg Psychiatry 81:286-9. 2010
    ..Biomechanical assessment of carotid plaques using high-resolution MRI can help examine the relationship between the timing of carotid plaque symptomology and maximum simulated plaque stress concentration...
  50. ncbi request reprint Estimation of physiologic ability and surgical stress (E-PASS) as a predictor of immediate outcome after elective abdominal aortic aneurysm surgery
    Tjun Tang
    Vascular Unit, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK
    Am J Surg 194:176-82. 2007
    ..The aim of this study was to assess its value in predicting mortality and morbidity after open elective abdominal aortic aneurysm (AAA) repair...
  51. doi request reprint Great saphenous vein harvesting: a systematic review and meta-analysis of open versus endoscopic techniques
    Rosemary Anne Cadwallader
    Cambridge Vascular Unit, Cambridge University Hospitals NHS Foundation Trust, UK
    Vasc Endovascular Surg 43:561-6. 2009
    ..We undertook a systematic review and meta-analysis to compare morbidity associated with these 2 techniques...
  52. ncbi request reprint Endovascular repair of infrarenal abdominal aortic aneurysms
    Umar Sadat
    Cambridge Vascular Unit, Cambridge CB2 0QQ, UK
    Br J Hosp Med (Lond) 70:151-3. 2009
    ..This article summarizes the key aspects of endovascular aneurysm repair and different techniques of endovascular stenting...
  53. doi request reprint Carotid stenosis assessment with multi-detector CT angiography: comparison between manual and automatic segmentation methods
    Chengcheng Zhu
    Department of Radiology, Cambridge University Hospitals Foundation Trust, University of Cambridge, Box 218, Cambridge CB2 0QQ, UK
    Int J Cardiovasc Imaging 29:899-905. 2013
    ..82) and MIP (ICC = 0.86) images. Carotid stenosis quantification using an automatic segmentation method has higher reproducibility compared with manual methods...
  54. doi request reprint Remote ischemic preconditioning in major vascular surgery
    Stewart R Walsh
    Cambridge Vascular Unit, Addenbrooke s Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom
    J Vasc Surg 49:240-3. 2009
    ..Remote ischemic preconditioning is easily performed and likely to prove highly cost-effective. large-scale trials of the technique are warranted in patients undergoing major vascular surgery...
  55. doi request reprint Three-dimensional volumetric analysis of atherosclerotic plaques: a magnetic resonance imaging-based study of patients with moderate stenosis carotid artery disease
    Umar Sadat
    University Department of Radiology, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
    Int J Cardiovasc Imaging 26:897-904. 2010
    ..PH, which is prevalent and consistent in such plaques, may be a better indicator of plaque vulnerability during that period...
  56. doi request reprint Early laparoscopy versus active observation in acute abdominal pain: systematic review and meta-analysis
    Adam Q Maggio
    Department of General Surgery, Addenbrooke s Hospital, Cambridge, UK
    Int J Surg 6:400-3. 2008
    ..Traditionally, such patients were managed by active observation and repeated clinical assessment over a period of time. More recently, the use of early laparoscopy has been advocated...
  57. doi request reprint Partially or completely absorbable versus nonabsorbable mesh repair for inguinal hernia: a systematic review and meta-analysis
    Sheraz R Markar
    Department of General Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
    Surg Laparosc Endosc Percutan Tech 20:213-9. 2010
    ..The long-term complications after implantation of a prosthetic mesh in inguinal hernia repair remain a concern. Recent development of new mesh materials has resulted in meshes with lower weight (LW) and with better biocompatibility...
  58. doi request reprint Arterial luminal curvature and fibrous-cap thickness affect critical stress conditions within atherosclerotic plaque: an in vivo MRI-based 2D finite-element study
    Zhongzhao Teng
    University Department of Radiology, University of Cambridge, Level 5, Box 218, Addenbrooke s Hospital, Hills Road, Cambridge CB20QQ, UK
    Ann Biomed Eng 38:3096-101. 2010
    ..Stress analysis at FC(MIN) and LC(MAX) should be used for a refined mechanical risk assessment of atherosclerotic plaques, since material failure at either site may result in rupture...
  59. doi request reprint Non-uniform shrinkage for obtaining computational start shape for in-vivo MRI-based plaque vulnerability assessment
    Yuan Huang
    University Department of Radiology, University of Cambridge, Cambridge, UK
    J Biomech 44:2316-9. 2011
    ..However, in order to make accurate predictions, the computational model must be based on the loading-free geometry. A shrinkage procedure can be used to obtain the computational start shape...
  60. doi request reprint Biomechanical structural stresses of atherosclerotic plaques
    Umar Sadat
    University Department of Radiology, University of Cambridge, Addenbrooke s Hospital, Hills Road, Cambridge, UK
    Expert Rev Cardiovasc Ther 8:1469-81. 2010
    ..Parameter studies investigating the effect of morphologic factors on the critical biomechanical stresses and limitations of current simulation models are also reviewed...
  61. ncbi request reprint Mycotic pseudoaneurysm of the superficial femoral artery in a patient with Cushing disease: case report and literature review
    David J Bowden
    Department of Radiology, Cambridge Vascular Unit, Addenbrooke s Hospital, Cambridge University Teaching Hospitals NHS Foundation Trust, Cambridge, UK
    Vascular 17:163-7. 2009
    ..This unusual case highlights the potential for serious adverse cardiovascular sequelae of Cushing disease and the need for awareness of such complications in this patient group...
  62. doi request reprint Iron oxide particles for atheroma imaging
    Tjun Y Tang
    University Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, UK
    Arterioscler Thromb Vasc Biol 29:1001-8. 2009
    ....
  63. pmc Role of carotid duplex imaging in carotid screening programmes - an overview
    Muhammad A Saleem
    Cambridge Vascular Unit, Addenbrooke s Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
    Cardiovasc Ultrasound 6:34. 2008
    ..Each year more than 110,000 people in England suffer from a stroke which costs the National Health Service (NHS) over GBP2.8 billion. Thus, it is imperative that patients at risk be screened for underlying carotid artery atherosclerosis...
  64. ncbi request reprint Mitral valve repair versus replacement in the elderly population
    Sheraz R Markar
    Department of Cardiothoracic Surgery, Papworth Hospital, Cambridge, UK
    J Heart Valve Dis 20:265-71. 2011
    ..The study aim was to evaluate the available literature comparing mitral valve repair (MVRep) versus mitral valve replacement (MVR) in the elderly population, and to provide a pooled analysis regarding this issue...
  65. doi request reprint Management of the left subclavian artery during endovascular repair of the thoracic aorta
    Nadim Noor
    Cambridge Vascular Unit, Cambridge University Hospitals, Addenbrookes NHS Foundation Trust, Cambridge, UK
    J Endovasc Ther 15:168-76. 2008
    ....
  66. doi request reprint Diffusion-weighted magnetic resonance imaging for the detection of lipid-rich necrotic core in carotid atheroma in vivo
    Victoria Eleanor Young
    University Department of Radiology, Addenbrooke s Hospital, Box 218, Hills Road, Cambridge, CB2 0QQ, UK
    Neuroradiology 52:929-36. 2010
    ..Previous magnetic resonance (MR) ex vivo studies have shown that diffusion-weighted imaging (DWI) can detect lipid-rich necrotic core (LR/NC) and fibrous cap. This study aims to establish if this is achievable in vivo...
  67. ncbi request reprint Endovascular repair of a penetrating thoracic aortic ulcer presenting with left recurrent laryngeal nerve palsy
    Umar Sadat
    Cambridge Vascular Unit, Addenbrooke s Hospital, Cambridge, United Kingdom
    Vasc Endovascular Surg 41:556-8. 2007
    ..Successful repair of the pseudoaneurysm was undertaken by endovascular technique with marked resolution of hoarseness after 1 year of follow-up...
  68. ncbi request reprint Preoperative glomerular filtration rate and outcome following open abdominal aortic aneurysm repair
    Stewart R Walsh
    Cambridge Vascular Unit, Addenbrooke s Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom
    Vasc Endovascular Surg 41:225-9. 2007
    ..It should replace serum creatinine as the standard index of renal function before open abdominal aortic aneurysm repair...
  69. doi request reprint Neurological complications after left subclavian artery coverage during thoracic endovascular aortic repair: a systematic review and meta-analysis
    David G Cooper
    Cambridge Vascular Unit, Cambridge University Hospitals NHS Trust, Addenbrooke s Hospital, Cambridge, United Kingdom
    J Vasc Surg 49:1594-601. 2009
    ..We assessed this increased risk and the role of revascularization by undertaking a systematic review and meta-analysis of the literature...
  70. pmc Continuous wound infusion of local anaesthetic agents following colorectal surgery: systematic review and meta-analysis
    Alan Karthikesalingam
    Department of General Surgery, Addenbrooke s Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB22QQ, United Kingdom
    World J Gastroenterol 14:5301-5. 2008
    ..To provide a specific review and meta-analysis of the available evidence for continuous wound infusion of local anaesthetic agents following midline laparotomy for major colorectal surgery...
  71. doi request reprint Cerebral hemodynamic changes following carotid endarterectomy: 'cerebral hyperperfusion syndrome'
    Ayesha Noorani
    Cambridge Vascular Unit, Addenbrooke s Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
    Expert Rev Neurother 10:217-23. 2010
    ..This review concentrates on the mechanism, current management and identification of risk factors that can predispose to this rare but potentially life threatening complication...
  72. ncbi request reprint Endovascular repair of nonruptured thoracic aortic aneurysms: systematic review
    Syed T Mustafa
    Academic Vascular Department, Sheffield University, Sheffield, United Kingdom
    Vascular 18:28-33. 2010
    ..9%. The 12-month mortality rate was 14.2%. Endovascular repair shows encouraging short-term results. It is associated with significantly less mortality and morbidity, but long-term results need to be further investigated...
  73. doi request reprint Images in vascular medicine. Management of giant cavernous renal arteriovenous malformation
    Jagjeeth Naik
    Cambridge Vascular Unit, Department of Vascular Surgery, Addenbrooke s Hospital, Cambridge, UK
    Vasc Med 13:175-6. 2008
  74. doi request reprint Internal iliac artery branch graft for common iliac artery aneurysm following previous open abdominal aortic aneurysm repair
    J Naik
    Regional Vascular Unit, Cambridge University Hospitals NHS Trust, Box 201, Addenbrooke s Hospital, Hills Road, Cambridge CB2 2QQ, UK
    Eur J Vasc Endovasc Surg 35:436-8. 2008
    ....
  75. doi request reprint An emergency EVAR service reduces mortality in ruptured abdominal aortic aneurysms
    U Sadat
    Cambridge Vascular Unit, Addenbrooke s Hospital, Hills Road, Cambridge, UK
    Eur J Vasc Endovasc Surg 37:189-93. 2009
    ..The aim of this study was to compare all in-hospital mortality for ruptured abdominal aortic aneurysms (rAAAs) before and after the establishment of an emergency EVAR (eEVAR) service...
  76. doi request reprint Abdominal aortic aneurysm surgery in renal, cardiac and hepatic transplant recipients
    U Sadat
    Cambridge Vascular Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK
    Eur J Vasc Endovasc Surg 40:443-9. 2010
    ..In addition to these surgical techniques, various aspects of medical management for renal, cardiac and hepatic transplant recipients undergoing AAA repair are discussed...
  77. ncbi request reprint Comparison of risk-scoring methods in predicting the immediate outcome after elective open abdominal aortic aneurysm surgery
    T Y Tang
    Cambridge Vascular Unit, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK
    Eur J Vasc Endovasc Surg 34:505-13. 2007
    ....
  78. pmc Assessment of pre-operative delays in the management of elective abdominal aortic aneurysms
    U Sadat
    Cambridge Vascular Unit, Addenbrooke s Hospital NHS Foundation Trust, Cambridge, UK
    Ann R Coll Surg Engl 90:65-8. 2008
    ..This process may delay surgery and some aneurysms may rupture prior to intervention. The aim of this study was to quantify these delays...
  79. ncbi request reprint Physiotherapy as a cause of hypothenar hammer syndrome
    Umar Sadat
    J Hand Surg Eur Vol 32:715-6. 2007