Chetana Sachidanandan

Summary

Publications

  1. Muthukumarasamy K, Handore K, Kakade D, Shinde M, Ranjan S, Kumar N, et al. Identification of noreremophilane-based inhibitors of angiogenesis using zebrafish assays. Org Biomol Chem. 2016;14:1569-78 pubmed publisher
    ..We synthesized several derivatives of this class of noreremophilanes and performed structure-activity relationship studies in zebrafish to identify more potent and less toxic analogs of the original structure. ..
  2. Babu A, Kamaraj M, Basu M, Mukherjee D, Kapoor S, Ranjan S, et al. Chemical and genetic rescue of an ep300 knockdown model for Rubinstein Taybi Syndrome in zebrafish. Biochim Biophys Acta Mol Basis Dis. 2018;1864:1203-1215 pubmed publisher
    ..Thus, modeling rare human genetic disorders in zebrafish allows for functional understanding of the genes involved and can also yield small molecule candidates towards therapeutic goals. ..
  3. Asad Z, Pandey A, Babu A, Sun Y, Shevade K, Kapoor S, et al. Rescue of neural crest-derived phenotypes in a zebrafish CHARGE model by Sox10 downregulation. Hum Mol Genet. 2016;25:3539-3554 pubmed publisher
    ..migration, fate choice and differentiation and we suggest that sox10 deregulation is an important driver of the neural crest-derived aspects of Chd7 dependent CHARGE syndrome. ..