Myoung Gwi Ryou

Summary

Publications

  1. pmc Pyruvate minimizes rtPA toxicity from in vitro oxygen-glucose deprivation and reoxygenation
    Myoung Gwi Ryou
    Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, 3500 Camp Bowie Boulevard, Fort Worth, TX, 76107 2699 USA
    Brain Res 1530:66-75. 2013
  2. ncbi request reprint Pyruvate-fortified cardioplegia suppresses oxidative stress and enhances phosphorylation potential of arrested myocardium
    E Marty Knott
    Department of Integrative Physiology, University of North Texas Health Science Center, 3500 Camp Bowie Blvd, Fort Worth, TX 76107 2699, USA
    Am J Physiol Heart Circ Physiol 289:H1123-30. 2005
  3. ncbi request reprint Pyruvate mitigates oxidative stress during reperfusion of cardioplegia-arrested myocardium
    E Marty Knott
    Department of Integrative Physiology, University of North Texas Health Science Center, Fort Worth, Texas 76107 2699, USA
    Ann Thorac Surg 81:928-34. 2006
  4. pmc Reversing the Warburg effect as a treatment for glioblastoma
    Ethan Poteet
    Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    J Biol Chem 288:9153-64. 2013
  5. ncbi request reprint Beta1-Adrenergic receptor antagonism abrogates cardioprotective effects of intermittent hypoxia
    Robert T Mallet
    Department of Integrative Physiology, University of North Texas Health Science Center, 3500 Camp Bowie Boulevard, Fort Worth, TX 76107 2699, USA
    Basic Res Cardiol 101:436-46. 2006
  6. ncbi request reprint In vitro protection by pyruvate against cadmium-induced cytotoxicity in hippocampal HT-22 cells
    Ethan Poteet
    Department of Pharmacology and Neuroscience, University of North Texas Health Science Center at Fort Worth, Fort Worth, TX, USA
    J Appl Toxicol 34:903-13. 2014
  7. pmc Pyruvate protects the brain against ischemia-reperfusion injury by activating the erythropoietin signaling pathway
    Myoung Gwi Ryou
    Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, 3500 Camp Bowie Boulevard, Fort Worth, TX 76107 2699, USA
    Stroke 43:1101-7. 2012
  8. doi request reprint Pyruvate-enriched cardioplegia suppresses cardiopulmonary bypass-induced myocardial inflammation
    Myoung Gwi Ryou
    Department of Integrative Physiology, University of North Texas Health Science Center, Fort Worth, Texas 76107 2699, USA
    Ann Thorac Surg 90:1529-35. 2010
  9. pmc Involvement of p38 MAPK in reactive astrogliosis induced by ischemic stroke
    Gourav Roy Choudhury
    Department of Pharmacology and Neuroscience, University of North Texas Health Science Center at Fort Worth, 3500 Camp Bowie Blvd, Fort Worth, TX 76107, USA
    Brain Res 1551:45-58. 2014
  10. doi request reprint Hypoxic conditioning suppresses nitric oxide production upon myocardial reperfusion
    Myoung Gwi Ryou
    Department of Integrative Physiology, University of North Texas Health Science Center, 3500 Camp Bowie Boulevard, Fort Worth, TX 76107 2699, USA
    Exp Biol Med (Maywood) 233:766-74. 2008

Collaborators

Detail Information

Publications11

  1. pmc Pyruvate minimizes rtPA toxicity from in vitro oxygen-glucose deprivation and reoxygenation
    Myoung Gwi Ryou
    Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, 3500 Camp Bowie Boulevard, Fort Worth, TX, 76107 2699 USA
    Brain Res 1530:66-75. 2013
    ..These results support the proposed use of pyruvate as an adjuvant to dampen the side effects of rtPA treatment, thereby extending rtPA's therapeutic window. ..
  2. ncbi request reprint Pyruvate-fortified cardioplegia suppresses oxidative stress and enhances phosphorylation potential of arrested myocardium
    E Marty Knott
    Department of Integrative Physiology, University of North Texas Health Science Center, 3500 Camp Bowie Blvd, Fort Worth, TX 76107 2699, USA
    Am J Physiol Heart Circ Physiol 289:H1123-30. 2005
    ..Pyruvate cardioplegia doubled [PCr]/([Cr][P(i)]) versus control and lactate cardioplegia after reperfusion. Pyruvate cardioplegia mitigates oxidative stress during cardioplegic arrest and enhances myocardial energy state on reperfusion...
  3. ncbi request reprint Pyruvate mitigates oxidative stress during reperfusion of cardioplegia-arrested myocardium
    E Marty Knott
    Department of Integrative Physiology, University of North Texas Health Science Center, Fort Worth, Texas 76107 2699, USA
    Ann Thorac Surg 81:928-34. 2006
    ....
  4. pmc Reversing the Warburg effect as a treatment for glioblastoma
    Ethan Poteet
    Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    J Biol Chem 288:9153-64. 2013
    ..In summary, the current study provides the first in vitro proof of concept that reversal of Warburg effect might be a novel therapy for GBM...
  5. ncbi request reprint Beta1-Adrenergic receptor antagonism abrogates cardioprotective effects of intermittent hypoxia
    Robert T Mallet
    Department of Integrative Physiology, University of North Texas Health Science Center, 3500 Camp Bowie Boulevard, Fort Worth, TX 76107 2699, USA
    Basic Res Cardiol 101:436-46. 2006
    ..Thus, episodic beta1-adrenergic activation during IHC evokes progressive development of powerful resistance to myocardial ischemia...
  6. ncbi request reprint In vitro protection by pyruvate against cadmium-induced cytotoxicity in hippocampal HT-22 cells
    Ethan Poteet
    Department of Pharmacology and Neuroscience, University of North Texas Health Science Center at Fort Worth, Fort Worth, TX, USA
    J Appl Toxicol 34:903-13. 2014
    ..Our study provides the first evidence that pyruvate might offer promising therapy for cadmium poisoning. Copyright © 2013 John Wiley & Sons, Ltd. ..
  7. pmc Pyruvate protects the brain against ischemia-reperfusion injury by activating the erythropoietin signaling pathway
    Myoung Gwi Ryou
    Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, 3500 Camp Bowie Boulevard, Fort Worth, TX 76107 2699, USA
    Stroke 43:1101-7. 2012
    ..We tested the hypothesis that pyruvate protects the brain against ischemia-reperfusion injury by inducing endogenous erythropoietin (EPO) expression...
  8. doi request reprint Pyruvate-enriched cardioplegia suppresses cardiopulmonary bypass-induced myocardial inflammation
    Myoung Gwi Ryou
    Department of Integrative Physiology, University of North Texas Health Science Center, Fort Worth, Texas 76107 2699, USA
    Ann Thorac Surg 90:1529-35. 2010
    ..This study tested whether cardioplegia enriched with the intermediary metabolite and antioxidant pyruvate dampens postbypass myocardial inflammation...
  9. pmc Involvement of p38 MAPK in reactive astrogliosis induced by ischemic stroke
    Gourav Roy Choudhury
    Department of Pharmacology and Neuroscience, University of North Texas Health Science Center at Fort Worth, 3500 Camp Bowie Blvd, Fort Worth, TX 76107, USA
    Brain Res 1551:45-58. 2014
    ..Our findings suggest that p38 MAPK signaling pathway plays an important role in the ischemic stroke-induced astrogliosis and thus may serve as a novel target to control glial scar formation. ..
  10. doi request reprint Hypoxic conditioning suppresses nitric oxide production upon myocardial reperfusion
    Myoung Gwi Ryou
    Department of Integrative Physiology, University of North Texas Health Science Center, 3500 Camp Bowie Boulevard, Fort Worth, TX 76107 2699, USA
    Exp Biol Med (Maywood) 233:766-74. 2008
    ..Attenuation of the NOS/NO system may contribute to IHC-induced protection of myocardium from ischemia-reperfusion injury...
  11. pmc Involvement of estrogen receptor β5 in the progression of glioma
    Wenjun Li
    Department of Pharmacology and Neuroscience, Institute for Alzheimer s Disease and Aging Research, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    Brain Res 1503:97-107. 2013
    ..Our findings suggest hypoxia induced ERβ5 expression in glioma as a self-protective mechanism against tumor proliferation and that ERβ5 might serve as a therapeutic target for the treatment of glioma...