Svetlana Strukova

Summary

Country: Russia

Publications

  1. ncbi Effect of enteropeptidase on survival of cultured hippocampal neurons under conditions of glutamate toxicity
    A M Makarova
    Faculty of Biology, Lomonosov Moscow State University, Moscow, 119991, Russia
    Biochemistry (Mosc) 75:1153-9. 2010
  2. doi Activated protein C prevents glutamate- and thrombin-induced activation of nuclear factor-kappaB in cultured hippocampal neurons
    L Gorbacheva
    Lomonosov Moscow State University, Department of Human and Animal Physiology, Moscow, Russia
    Neuroscience 165:1138-46. 2010
  3. doi The impact of duration of antibiotic exposure on bacterial resistance predictions using in vitro dynamic models
    Maria V Smirnova
    Department of Pharmacokinetics and Pharmacodynamics, Gause Institute of New Antibiotics, Russian Academy of Medical Sciences, 11 Bolshaya Pirogovskaya Street, Moscow, 119021 Russia
    J Antimicrob Chemother 64:815-20. 2009
  4. ncbi Thrombin as a regulator of inflammation and reparative processes in tissues
    S M Strukova
    Department of Human and Animal Physiology, School of Biology, Lomonosov Moscow State University, Moscow, 119899 Russia
    Biochemistry (Mosc) 66:8-18. 2001
  5. ncbi Immobilized thrombin receptor agonist peptide accelerates wound healing in mice
    S M Strukova
    Faculty of Biology, Lomonosov Moscow State University, Russia
    Clin Appl Thromb Hemost 7:325-9. 2001
  6. ncbi Role of platelets and serine proteinases in coupling of blood coagulation and inflammation
    S M Strukova
    Faculty of Biology, Lomonosov Moscow State University, Moscow 119992, Russia
    Biochemistry (Mosc) 69:1067-81. 2004
  7. ncbi Blood coagulation-dependent inflammation. Coagulation-dependent inflammation and inflammation-dependent thrombosis
    Svetlana Strukova
    Department of Human and Animal Physiology, Faculty of Biology, Lomonosov Moscow State University, Moscow, 119992, Russia
    Front Biosci 11:59-80. 2006
  8. doi NF-κB-dependent and -independent pathways in the protective effects of activated protein C in hippocampal and cortical neurons at excitotoxicity
    Lubov Gorbacheva
    Lomonosov Moscow State University, Department of Human and Animal Physiology, 119991 Moscow, Russia
    Neurochem Int 63:101-11. 2013
  9. ncbi [The role of PAR family receptors in activation of mast cells in the norm and in acute inflammation in rats]
    E V Kiseleva
    M. V. Lomonossov State University, 119899, Vorobievy Gory, Moscow, Russia
    Ross Fiziol Zh Im I M Sechenova 87:1527-33. 2001
  10. ncbi Effect of synthetic peptide thrombin receptor agonist encapsulated in microparticles based on lactic and glycolic acid copolymer on healing of experimental skin wounds in mice
    T N Dugina
    Biological Faculty, M V Lomonosov Moscow State University, Moscow, Russia
    Bull Exp Biol Med 138:463-6. 2004

Collaborators

  • S Ishiwata
  • O P Balezina
  • T N Dugina
  • E Glusa
  • T Aoki
  • L R Gorbacheva
  • V G Pinelis
  • Lubov Gorbacheva
  • Vsevolod Pinelis
  • Georg Reiser
  • L Gorbacheva
  • A M Makarova
  • Lyubov Gorbacheva
  • Maria V Smirnova
  • Kira Stashevskaya
  • T P Storozhevykh
  • J Ide
  • Rolf Stricker
  • E V Kiseleva
  • G Reiser
  • A G Mikhailova
  • L D Rumsh
  • V Pinelis
  • I V Savinkova
  • Elena V Strukova
  • Stephen H Zinner
  • Svetlana A Dovzhenko
  • Michael B Kobrin
  • Elena Sokolova
  • Yury A Portnoy
  • Olga Davidova
  • Sergey N Vostrov
  • Alexander A Firsov
  • O N Davydova
  • Igor Prudchenko
  • Vitaly Zubov
  • Christian Grandfils
  • Elena Markvicheva
  • S Ishivata
  • E Gluza

Detail Information

Publications18

  1. ncbi Effect of enteropeptidase on survival of cultured hippocampal neurons under conditions of glutamate toxicity
    A M Makarova
    Faculty of Biology, Lomonosov Moscow State University, Moscow, 119991, Russia
    Biochemistry (Mosc) 75:1153-9. 2010
    ..High concentrations of BEK and L-HEP caused the death of neurons mainly through necrosis...
  2. doi Activated protein C prevents glutamate- and thrombin-induced activation of nuclear factor-kappaB in cultured hippocampal neurons
    L Gorbacheva
    Lomonosov Moscow State University, Department of Human and Animal Physiology, Moscow, Russia
    Neuroscience 165:1138-46. 2010
    ..APC induces the reduction of the nuclear level of NF-kappaB p65 in hippocampal neurons at glutamate-induced excitotoxicity via binding to EPCR and subsequent PAR-1 activation and signaling...
  3. doi The impact of duration of antibiotic exposure on bacterial resistance predictions using in vitro dynamic models
    Maria V Smirnova
    Department of Pharmacokinetics and Pharmacodynamics, Gause Institute of New Antibiotics, Russian Academy of Medical Sciences, 11 Bolshaya Pirogovskaya Street, Moscow, 119021 Russia
    J Antimicrob Chemother 64:815-20. 2009
    ....
  4. ncbi Thrombin as a regulator of inflammation and reparative processes in tissues
    S M Strukova
    Department of Human and Animal Physiology, School of Biology, Lomonosov Moscow State University, Moscow, 119899 Russia
    Biochemistry (Mosc) 66:8-18. 2001
    ..Mechanisms of regulatory effects of thrombin on mast cells associated with nitric oxide release are discussed...
  5. ncbi Immobilized thrombin receptor agonist peptide accelerates wound healing in mice
    S M Strukova
    Faculty of Biology, Lomonosov Moscow State University, Russia
    Clin Appl Thromb Hemost 7:325-9. 2001
    ..The encapsulated TRAP is suggested to accelerate wound healing due to the anti-inflammatory effects and earlier development of the proliferative phase of wound healing...
  6. ncbi Role of platelets and serine proteinases in coupling of blood coagulation and inflammation
    S M Strukova
    Faculty of Biology, Lomonosov Moscow State University, Moscow 119992, Russia
    Biochemistry (Mosc) 69:1067-81. 2004
    ....
  7. ncbi Blood coagulation-dependent inflammation. Coagulation-dependent inflammation and inflammation-dependent thrombosis
    Svetlana Strukova
    Department of Human and Animal Physiology, Faculty of Biology, Lomonosov Moscow State University, Moscow, 119992, Russia
    Front Biosci 11:59-80. 2006
    ....
  8. doi NF-κB-dependent and -independent pathways in the protective effects of activated protein C in hippocampal and cortical neurons at excitotoxicity
    Lubov Gorbacheva
    Lomonosov Moscow State University, Department of Human and Animal Physiology, 119991 Moscow, Russia
    Neurochem Int 63:101-11. 2013
    ..Our findings demonstrate that, in the protective effect of APC in neurons at excitotoxicity, the NF-κB pathway is an important, but not the only pathway, and is significantly connected with neuronal survival at excitotoxicity...
  9. ncbi [The role of PAR family receptors in activation of mast cells in the norm and in acute inflammation in rats]
    E V Kiseleva
    M. V. Lomonossov State University, 119899, Vorobievy Gory, Moscow, Russia
    Ross Fiziol Zh Im I M Sechenova 87:1527-33. 2001
    ..Acceleration of the mast cell mediator secretion by the Xa factor and PAR-2 agonist, was revealed. An increase in the mast cell release induced by thrombin and TRAP-6 was shown in the acute peritonitis model...
  10. ncbi Effect of synthetic peptide thrombin receptor agonist encapsulated in microparticles based on lactic and glycolic acid copolymer on healing of experimental skin wounds in mice
    T N Dugina
    Biological Faculty, M V Lomonosov Moscow State University, Moscow, Russia
    Bull Exp Biol Med 138:463-6. 2004
    ..On day 7 the best healing parameters were also observed in wounds treated with PAR1-AP microparticles, which attests to shortening of the proliferation phase and acceleration of wound healing...
  11. ncbi Study of neurotrophic activity of thrombin on the model of regenerating mouse nerve
    O P Balezina
    Department of Human and Animal Physiology, Biological Faculty, M V Lomonosov Moscow State University, Moscow, Russia
    Bull Exp Biol Med 139:4-6. 2005
    ..The maximum neurotrophic effect was observed at low concentrations of thrombin (10 nM) and TRAP6 (10 microM)...
  12. ncbi Effect of PAR1 agonist on acetylcholine secretion in a newly formed neuromuscular synapse in mice
    O P Balezina
    Department of Human and Animal Physiology, Biological Faculty, M V Lomonosov Moscow State University
    Bull Exp Biol Med 144:653-6. 2007
    ..Protein kinase C inhibition was associated with reversal of the object of PARI agonist: transmission inhibition instead of facilitation...
  13. ncbi Receptors of the PAR family as a link between blood coagulation and inflammation
    T N Dugina
    Department of Human and Animal Physiology, School of Biology, Lomonosov Moscow State University, Moscow, 119899, Russia
    Biochemistry (Mosc) 67:65-74. 2002
    ..The presence of PAR receptors on mast cells is responsible for their reactivity to thrombin and factor Xa and defines their contribution to the association of inflammation and blood clotting processes...
  14. ncbi Thrombin receptor agonist peptide entrapped in poly(D,L)-lactide-co-glycolide microparticles: preparation and characterization
    Kira Stashevskaya
    Russian Academy of Sciences, Polymers for Biology Laboratory, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia
    J Microencapsul 24:129-42. 2007
    ..The results can allow one to optimize the microencapsulation procedure and to encounter a new promising approach to development of biodegradable polymer drug delivery systems for wound healing...
  15. ncbi Proteinase-activated receptor agonists stimulate the increase in intracellular Ca2+ in cardiomyocytes and proliferation of cardiac fibroblasts from chick embryos
    J Ide
    Department of Human and Animal Physiology, Biological Faculty, M V Lomonosov Moscow State University, Moscow
    Bull Exp Biol Med 144:760-3. 2007
    ..PAR2 agonists trypsin and peptide SLIGRL stimulated proliferation of cardiac fibroblasts. Our results indicate that cardiomyocytes and cardiac fibroblasts from chick embryos have at least two types of PAR (types 1 and 2)...
  16. ncbi Activated protein C via PAR1 receptor regulates survival of neurons under conditions of glutamate excitotoxicity
    L R Gorbacheva
    Biology Faculty, Lomonosov Moscow State University, Moscow, 119899, Russia
    Biochemistry (Mosc) 73:717-24. 2008
    ..1 nM APC on glutamate-induced cytotoxicity in the hippocampal neurons. Thus, APC at low concentrations, activating PAR1, prevents the death of hippocampal and cortical neurons under conditions of glutamate excitotoxicity...
  17. doi Endothelial protein C receptor is expressed in rat cortical and hippocampal neurons and is necessary for protective effect of activated protein C at glutamate excitotoxicity
    Lyubov Gorbacheva
    Department of Human and Animal Physiology, Lomonosov Moscow State University, Moscow, Russia
    J Neurochem 111:967-75. 2009
    ..Thus, we suggest that binding of APC to EPCR on neurons and subsequent activation of protease-activated receptor-1 by the complex of APC-EPCR promotes survival mechanisms after exposure of neurons to damaging factors...
  18. ncbi Modulation of hippocampal neuron survival by thrombin and factor Xa
    L R Gorbacheva
    Department of Human and Animal Physiology, Biological Faculty, Lomonosov Moscow State University, Moscow, 119899, Russia
    Biochemistry (Mosc) 71:1082-9. 2006
    ..Both of the serine proteases improved the recovery of neuronal Ca2+ homeostasis after glutamate treatment...