Research Topics
| Andrey AnisimovSummaryAffiliation: State Research Center for Applied Microbiology and Biotechnology Location: Obolensk, Russia Publications
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Detail Information
Publications
Amino acid and structural variability of Yersinia pestis LcrV proteinAndrey P Anisimov
State Research Center for Applied Microbiology and Biotechnology, 142279 Obolensk, Moscow Region, Russia
Infect Genet Evol 10:137-45. 2010..The polymorphisms at positions 18, 72 and 273 were accountable for differences in the oligomerization of LcrV...
Revision of the O-polysaccharide structure of Yersinia pseudotuberculosis O:1a; confirmation of the function of WbyM as paratosyltransferaseAnna N Kondakova
N D Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia
Carbohydr Res 350:98-102. 2012..S. Bioorg. Khim.1984, 10, 232-237). A comparative study by high-resolution ESI MS of the short-chain lipopolysaccharides from strain PB1 and a wbyM mutant thereof confirmed the function of wbyM as the paratosyltransferase gene...
Structure of the O-polysaccharide of Yersinia pseudotuberculosis O:2bAnna N Kondakova
N D Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia
Carbohydr Res 344:405-7. 2009..The following structure of the polysaccharide was established: alpha-Abep. 1-->3. -->2) alpha-D-Manp-(1-->3)-alpha-L-Fucp-(1-->3)-beta-D-GalpNAc-(1-->. where Abe stands for 3,6-dideoxy-D-xylo-hexose (abequose)...
The subcutaneous inoculation of pH 6 antigen mutants of Yersinia pestis does not affect virulence and immune response in miceAndrey P Anisimov
State Research Center for Applied Microbiology and Biotechnology, 142279 Obolensk, Serpukhov District, Moscow Region, Russia
J Med Microbiol 58:26-36. 2009..It was shown that the loss of synthesis or constitutive production of pH 6 antigen did not influence Y. pestis virulence or the average survival time of subcutaneously inoculated BALB/c naïve mice or animals immunized with this antigen...
Structure of the O-antigen of Yersinia pseudotuberculosis O:4bAnna N Kondakova
N D Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia
Carbohydr Res 344:152-4. 2009....
Reinvestigation of the O-antigens of Yersinia pseudotuberculosis: revision of the O2c and confirmation of the O3 antigen structuresAnna N Kondakova
N D Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia
Carbohydr Res 343:2486-8. 2008..The structure of the Y. pseudotuberculosis O3 antigen reported earlier was confirmed...
Insight into microevolution of Yersinia pestis by clustered regularly interspaced short palindromic repeatsYujun Cui
State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Beijing, China
PLoS ONE 3:e2652. 2008..pestis from 26 natural plague foci of China, the former Soviet Union and Mongolia were analyzed, for validating CRISPR-based genotyping method and better understanding adaptive microevolution of Y. pestis...
Structural diversity and endotoxic activity of the lipopolysaccharide of Yersinia pestisS V Dentovskaya
State Research Center for Applied Microbiology and Biotechnology, Obolensk, Moscow Region, Russia
Biochemistry (Mosc) 73:192-9. 2008..No correlation was found between the lethal toxicity of the LPS in vivo and its ability to induce TNF-alpha production in vitro...
Analysis of the three Yersinia pestis CRISPR loci provides new tools for phylogenetic studies and possibly for the investigation of ancient DNAGilles Vergnaud
Universite Paris Sud, Institut de Genetique et Microbiologie, Orsay, France
Adv Exp Med Biol 603:327-38. 2007..In addition, the assay can be run in any laboratory. Interpretation of the data is not dependent on accurate sequence data...
Relationship of the lipopolysaccharide structure of Yersinia pestis to resistance to antimicrobial factorsYuriy A Knirel
N D Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia
Adv Exp Med Biol 603:88-96. 2007..Resistance to polymyxin B also requires a high content of the cationic sugar, 4-amino-4-deoxy-L-arabinose, in lipid A...
Variability of the protein sequences of lcrV between epidemic and atypical rhamnose-positive strains of Yersinia pestisAndrey P Anisimov
Department of Infectious Diseases, State Research Center for Applied Microbiology and Biotechnology, Obolensk, Moscow Region, Russia
Adv Exp Med Biol 603:23-7. 2007..One possible explanation for polymorphism in amino acid sequences of LcrV among different strains is that strain-specific variation resulted from adaptation of the plague pathogen to different rodent and lagomorph hosts...
Structure of the O-antigen of Yersinia pseudotuberculosis O:4a revisedAnna N Kondakova
N D Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
Carbohydr Res 344:531-4. 2009..The structure of the Y. pseudotuberculosis O:4a antigen resembles that of Y. pseudotuberculosis O:2c, which differs in the presence of abequose (3,6-dideoxy-D-xylo-hexose) in place of tyvelose only...
Pleiotropic effects of the lpxM mutation in Yersinia pestis resulting in modification of the biosynthesis of major immunoreactive antigensV A Feodorova
Russian State Anti Plague Research Institute Microbe, 46, Universitetskaya Street, Saratov, 410005, Russia
Vaccine 27:2240-50. 2009..These findings indicate that the effects of the lpxM mutation on reduced virulence and enhanced immunity of the Y. pestis EV DeltalpxM is also associated with these pleiotropic changes and not just to changes in the lipid A acylation...
Reflectron MALDI TOF and MALDI TOF/TOF mass spectrometry reveal novel structural details of native lipooligosaccharidesLuisa Sturiale
CNR Istituto per la Chimica e la Tecnologia dei Polimeri, via P Gaifami 18, 95126 Catania, Italy
J Mass Spectrom 46:1135-42. 2011..These findings constitute a significant advancement in the analysis of such an important biomolecule by MALDI MS...
Functional characterization and biological significance of Yersinia pestis lipopolysaccharide biosynthesis genesS V Dentovskaya
State Research Center for Applied Microbiology and Biotechnology, Obolensk, Moscow Region, Russia
Biochemistry (Mosc) 76:808-22. 2011....
Low structural diversity of the O-polysaccharides of Photorhabdus asymbiotica subspp. asymbiotica and australis and their similarity to the O-polysaccharides of taxonomically remote bacteria including Francisella tularensisAnna N Kondakova
N D Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia
Carbohydr Res 346:1951-5. 2011....
Identification of the lipopolysaccharide core of Yersinia pestis and Yersinia pseudotuberculosis as the receptor for bacteriophage φA1122Saija Kiljunen
Department of Medical Biochemistry and Molecular Biology, Institute of Biomedicine, University of Turku, Turku, Finland
J Bacteriol 193:4963-72. 2011..e., also missing the Kdo/Ko region, was fully φA1122 resistant. Our data thus conclusively demonstrated that the φA1122 receptor is the Hep/Glc-Kdo/Ko region of the LPS core, a common structure in Y. pestis and Y. pseudotuberculosis...
Temperature-induced changes in the lipopolysaccharide of Yersinia pestis affect plasminogen activation by the pla surface proteaseMarjo Suomalainen
Department of Biosciences, FIN 00014 University of Helsinki, Helsinki, Finland
Infect Immun 78:2644-52. 2010..The temperature-induced changes in LPS are known to help Y. pestis to avoid innate immune responses, and our results strongly suggest that they also potentiate Pla-mediated proteolysis...
Tetraacylated lipopolysaccharide of Yersinia pestis can inhibit multiple Toll-like receptor-mediated signaling pathways in human dendritic cellsMaxim V Telepnev
Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA
J Infect Dis 200:1694-702. 2009....
Revision of the O-polysaccharide structure of Yersinia pseudotuberculosis O:1bAnna N Kondakova
N D Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia
Carbohydr Res 344:2421-3. 2009..M.; de Castro, C.; Kenyon, J.; Parrilli, M.; Reeves, P. R.; Molinaro, A.; Holst, O.; Skurnik, M. Carbohydr. Res.2009, 344, 1533-1540]...
Genotyping and phylogenetic analysis of Yersinia pestis by MLVA: insights into the worldwide expansion of Central Asia plague fociYanjun Li
Laboratory of Analytical Microbiology, State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Beijing, China
PLoS ONE 4:e6000. 2009....
A Yersinia pestis lpxM-mutant live vaccine induces enhanced immunity against bubonic plague in mice and guinea pigsV A Feodorova
Russian State Anti Plague Research Institute Microbe, 46 Universitetskaya Street, Saratov 410005, Russia
Vaccine 25:7620-8. 2007..5 x 10(4) CFU) of this vaccine. A subcutaneous challenge with 2000 median lethal doses (equal to 20,000 CFU) of fully virulent Y. pestis 231 strain, is a 6-10-fold higher dose than that which the EV NIIEG itself can protect against...
Effect of deletion of the lpxM gene on virulence and vaccine potential of Yersinia pestis in miceAndrey P Anisimov
State Research Center for Applied Microbiology and Biotechnology, Obolensk 142279, Moscow Region, Russia
J Med Microbiol 56:443-53. 2007..These studies suggest there is little impact from lipid A modifications on the virulence of Y. pestis strains but there are potential improvements in the protective properties in attenuated vaccine strains...
Treatment of plague: promising alternatives to antibioticsAndrey P Anisimov
Laboratory for Plague Microbiology, Department of Infectious Diseases, State Research Center for Applied Microbiology and Biotechnology, 142279 Obolensk, Serpukhov District, Moscow Region, Russia
J Med Microbiol 55:1461-75. 2006..The alternative therapies reported in this review should be further investigated by comprehensive studies of their clinical application for the treatment of plague...
The core structure of the lipopolysaccharide from the causative agent of plague, Yersinia pestisEvgeny V Vinogradov
N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospekt 47, Moscow 119991, Russia
Carbohydr Res 337:775-7. 2002..A minority of the LPS molecules lacks GlcNAc...
Structural features and structural variability of the lipopolysaccharide of Yersinia pestis, the cause of plagueYuriy A Knirel
N D Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia
J Endotoxin Res 12:3-9. 2006..A correlation between the LPS structure and properties of the LPS and bacterial cultures as well as the LPS biosynthesis control are briefly discussed...
Intraspecies and temperature-dependent variations in susceptibility of Yersinia pestis to the bactericidal action of serum and to polymyxin BAndrey P Anisimov
State Research Center for Applied Microbiology, Obolensk, Moscow Region 142279, Russia
Infect Immun 73:7324-31. 2005..The NHS resistance correlated with an elevated content of N-acetylglucosamine in the LPS. Structural variation in the LPS of Y. pestis correlates with the organism's ability to resist innate immunity in both fleas and mammals...
Cold temperature-induced modifications to the composition and structure of the lipopolysaccharide of Yersinia pestisYuriy A Knirel
N D Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow 119991, Russia
Carbohydr Res 340:1625-30. 2005..The data obtained suggest that cold temperature switches on an alternative mechanism of control of the synthesis of Y. pestis LPS...
Temperature-dependent variations and intraspecies diversity of the structure of the lipopolysaccharide of Yersinia pestisYuriy A Knirel
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow 119991, Russia
Biochemistry 44:1731-43. 2005..pestis and epidemiologic means to detect, classify, control and respond to Y. pestis infections...
Intraspecific diversity of Yersinia pestisAndrey P Anisimov
Department of Infectious Diseases, State Research Center for Applied Microbiology, 142279 Obolensk, Serpukhov District, Moscow Region, Russia
Clin Microbiol Rev 17:434-64. 2004..pestis strains based on genetic and phenotypic variation and show that there is a high level of diversity in these strains not reflected by ones obtained from sylvatic areas and patients in the Americas...
A recombinant prototrophic Yersinia pestis strain over-produces F1 antigen with enhanced serological activitySvetlana V Dentovskaya
State Research Center for Applied Microbiology, Obolensk, Moscow Region, Russia
Adv Exp Med Biol 529:419-21. 2003
The core structure of the lipopolysaccharide of Yersinia pestis strain KM218. Influence of growth temperatureEvgeny V Vinogradov
State Research Center for Applied Microbiology, Obolensk, Moscow Region, Russia
Adv Exp Med Biol 529:229-31. 2003
