Sergey Korotkov

Summary

Affiliation: Sechenov Institute of Evolutionary Physiology and Biochemistry, the Russian Academy of Sciences
Location: St. Petersburg, Russian Federation
Summary:
mitochondria: bioenergetic, ionic transport, the inner membrane potential and SH content, heavy metals, xenobiotics and pharmacological agents

Publications

  1. Korotkov S, Saris N. Influence of Tl(+) on mitochondrial permeability transition pore in Ca(2+)-loaded rat liver mitochondria. J Bioenerg Biomembr. 2011;43:149-62 pubmed publisher
    ..We discuss the possible participation of Ca(2+)-binding sites, located near the respiratory complex I and the adenine nucleotide translocase, in inducing opening of the MPTP. ..
  2. request reprint
    Korotkov S, Glazunov V, Nikitina E. [Respiration and ion permeability of the inner membrane in rat "sodium" liver mitochondria]. Tsitologiia. 1997;39:1046-54 pubmed
    ....
  3. request reprint
    Korotkov S, Nesterov V, Ryabchikov N. Study of the mechanism of action of diazoxide on rat heart mitochondria under calcium loading. Dokl Biochem Biophys. 2006;408:133-7 pubmed
  4. request reprint
    Korotkov S, Glazunov V, Rozengart E, Suvorov A, Nikitina E. Effects of Cd2+ and two cadmium organic complexes on isolated rat liver mitochondria. J Biochem Mol Toxicol. 1999;13:149-57 pubmed
    ..These results indicate that the cadmium organic complexes affect respiration and perturb ion permeability significantly stronger than Cd2+. ..
  5. request reprint
    Korotkov S, Brailovskaya I. Tl+ increases the permeability of the inner membranes of rat liver mitochondria for monovalent cations. Dokl Biochem Biophys. 2001;378:145-9 pubmed
  6. request reprint
    Korotkov S, Lapin A. Thallium induces opening of the mitochondrial permeability transition pore in the inner membrane of rat liver mitochondria. Dokl Biochem Biophys. 2003;392:247-52 pubmed
  7. request reprint
    Korotkov S, Skul skiĭ I. [Changes in the effect of Cd2+ on the respiration of isolated rat liver mitochondria after their preincubation with Ca2+, Sr2+, Ba2+, Mn2+ and ruthenium red]. Tsitologiia. 1996;38:500-9 pubmed
    ....
  8. Belyaeva E, Korotkov S, Saris N. In vitro modulation of heavy metal-induced rat liver mitochondria dysfunction: a comparison of copper and mercury with cadmium. J Trace Elem Med Biol. 2011;25 Suppl 1:S63-73 pubmed publisher
    ..Sequence of events manifested in the mitochondrial dysfunction produced by the metals under test was elucidated. ..
  9. request reprint
    Savina M, Emel yanova L, Korotkov S, Brailovskaya I, Nadeev A. Bioenergetics of mitochondria of the liver with biliary atresia during prolonged starvation. Dokl Biochem Biophys. 2009;425:80-3 pubmed
  10. request reprint
    Korotkov S, Nesterov V, Ryabchikov N. Study of the effect of SH-groups on respiration and swelling of rat heart mitochondria. Dokl Biochem Biophys. 2008;421:171-5 pubmed

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Collaborators

Detail Information

Publications33

  1. Korotkov S, Saris N. Influence of Tl(+) on mitochondrial permeability transition pore in Ca(2+)-loaded rat liver mitochondria. J Bioenerg Biomembr. 2011;43:149-62 pubmed publisher
    ..We discuss the possible participation of Ca(2+)-binding sites, located near the respiratory complex I and the adenine nucleotide translocase, in inducing opening of the MPTP. ..
  2. request reprint
    Korotkov S, Glazunov V, Nikitina E. [Respiration and ion permeability of the inner membrane in rat "sodium" liver mitochondria]. Tsitologiia. 1997;39:1046-54 pubmed
    ....
  3. request reprint
    Korotkov S, Nesterov V, Ryabchikov N. Study of the mechanism of action of diazoxide on rat heart mitochondria under calcium loading. Dokl Biochem Biophys. 2006;408:133-7 pubmed
  4. request reprint
    Korotkov S, Glazunov V, Rozengart E, Suvorov A, Nikitina E. Effects of Cd2+ and two cadmium organic complexes on isolated rat liver mitochondria. J Biochem Mol Toxicol. 1999;13:149-57 pubmed
    ..These results indicate that the cadmium organic complexes affect respiration and perturb ion permeability significantly stronger than Cd2+. ..
  5. request reprint
    Korotkov S, Brailovskaya I. Tl+ increases the permeability of the inner membranes of rat liver mitochondria for monovalent cations. Dokl Biochem Biophys. 2001;378:145-9 pubmed
  6. request reprint
    Korotkov S, Lapin A. Thallium induces opening of the mitochondrial permeability transition pore in the inner membrane of rat liver mitochondria. Dokl Biochem Biophys. 2003;392:247-52 pubmed
  7. request reprint
    Korotkov S, Skul skiĭ I. [Changes in the effect of Cd2+ on the respiration of isolated rat liver mitochondria after their preincubation with Ca2+, Sr2+, Ba2+, Mn2+ and ruthenium red]. Tsitologiia. 1996;38:500-9 pubmed
    ....
  8. Belyaeva E, Korotkov S, Saris N. In vitro modulation of heavy metal-induced rat liver mitochondria dysfunction: a comparison of copper and mercury with cadmium. J Trace Elem Med Biol. 2011;25 Suppl 1:S63-73 pubmed publisher
    ..Sequence of events manifested in the mitochondrial dysfunction produced by the metals under test was elucidated. ..
  9. request reprint
    Savina M, Emel yanova L, Korotkov S, Brailovskaya I, Nadeev A. Bioenergetics of mitochondria of the liver with biliary atresia during prolonged starvation. Dokl Biochem Biophys. 2009;425:80-3 pubmed
  10. request reprint
    Korotkov S, Nesterov V, Ryabchikov N. Study of the effect of SH-groups on respiration and swelling of rat heart mitochondria. Dokl Biochem Biophys. 2008;421:171-5 pubmed
  11. request reprint
    Brailovskaya I, Korotkov S, Emel yanova L, Mokhova E. Stimulation by cytochrome c of the external pathway of NADH oxidation and ascorbate oxidation in the presence of TMPD. Dokl Biochem Biophys. 2006;408:123-6 pubmed
  12. request reprint
    Korotkov S, Nikitina E, Glazunov V, Iagodina O. Effect of thallium ions on isolated mitochondria of rat liver in the presence of nonactin. Dokl Biochem Biophys. 2005;401:97-103 pubmed
  13. request reprint
    Skul skiĭ I, Korotkov S, Glazunov V, Ivanova T, Savina M. [Effect of cadmium ions on the respiration, cation transport and morphology of the liver mitochondria in the rat and the lamprey]. Tsitologiia. 1988;30:956-62 pubmed
    ..The effect of Cd2+ on the lamprey liver mitochondria is more pronounced than in the case of rats. ..
  14. request reprint
    Korotkov S, Nesterov V, Schaefer S. On the effect of diazoxide on isolated mitochondria from rat myocardium. Dokl Biochem Biophys. 2002;387:306-9 pubmed
  15. request reprint
    Korotkov S, Glazunov V, Rozengart E, Suvorov A. [The action of organic cadmium complexes of different degrees of hydrophobicity on rat liver mitochondria]. Tsitologiia. 1996;38:1075-83 pubmed
    ..It is assumed that transport of Cd(ANB) in mitochondria, opposite to that of Cd(CBG), is not carried out across hydrophobic domains of the mitochondrial membrane. ..
  16. request reprint
    Belyaeva E, Glazunov V, Korotkov S. Cyclosporin A-sensitive permeability transition pore is involved in Cd(2+)-induced dysfunction of isolated rat liver mitochondria: doubts no more. Arch Biochem Biophys. 2002;405:252-64 pubmed
    ..Cd(2+) effects are discussed in terms of comparison with those of Zn(2+) and PhAsO. ..
  17. request reprint
    Belyaeva E, Glazunov V, Nikitina E, Korotkov S. Bivalent metal ions modulate Cd2+ effects on isolated rat liver mitochondria. J Bioenerg Biomembr. 2001;33:303-18 pubmed
    ..The observations are interpreted in terms of a dual effect of cadmium on respiratory chain activity and permeability transition. ..
  18. request reprint
    Korotkov S, Skulskii I, Glazunov V. Cd2+ effects on respiration and swelling of rat liver mitochondria were modified by monovalent cations. J Inorg Biochem. 1998;70:17-23 pubmed
    ....
  19. request reprint
    Korotkov S, Skul skiĭ I. [The effect of Cd2+ on the respiration and swelling of isolated rat liver mitochondria in incubation media of different compositions]. Tsitologiia. 1996;38:1191-202 pubmed
    ....
  20. request reprint
    Belyaeva E, Glazunov V, Korotkov S. Cd2+ -promoted mitochondrial permeability transition: a comparison with other heavy metals. Acta Biochim Pol. 2004;51:545-51 pubmed
    ..Dithiothreitol induced a basal respiration release if added after high [Cd(2+)] and [Hg(2+)], and the stimulation was CsA-insensitive. ..
  21. request reprint
    Korotkov S, Nesterov V, Rudenko I, Brailovskaya I. Effects of lithium on isolated rat heart mitochondria. Dokl Biochem Biophys. 2010;430:45-9 pubmed
  22. Korotkov S. Effects of Tl(+) on ion permeability, membrane potential and respiration of isolated rat liver mitochondria. J Bioenerg Biomembr. 2009;41:277-87 pubmed publisher
    ..The observed decrease of state 3 and DNP-stimulated respiration in the nitrate media resulted from the mitochondrial swelling rather than from an inhibition of respiratory enzymes as is the case with the bivalent heavy metals. ..
  23. request reprint
    Prikhodko E, Brailovskaya I, Korotkov S, Mokhova E. Features of mitochondrial energetics in living unicellular eukaryote Tetrahymena pyriformis. A model for study of mammalian intracellular adaptation. Biochemistry (Mosc). 2009;74:371-6 pubmed
    ..pyriformis stained with the Delta psi-sensitive probe MitoTracker Red. These data suggest that T. pyriformis cells are useful as a model for study of mitochondrial role in adaptation at the intracellular level. ..
  24. request reprint
    Korotkov S, Nesterov V, Demina I. Effect of sodium load of the matrix on properties of isolated rat heart mitochondria. Dokl Biochem Biophys. 2009;424:56-60 pubmed
  25. request reprint
    Glazunov V, Korotkov S. [Respiration and swelling of isolated rat liver mitochondria, modified by replacing potassium for sodium in their matrix]. Dokl Akad Nauk. 1997;356:551-4 pubmed
  26. Korotkov S, Emel yanova L, Yagodina O. Inorganic phosphate stimulates the toxic effects of Tl+ in rat liver mitochondria. J Biochem Mol Toxicol. 2008;22:148-57 pubmed publisher
    ....
  27. request reprint
    Korotkov S, Nesterov V, Emel yanova L, Ryabchikov N. Involvement of SH-groups during interaction of diazoxide with the inner membrane of rat heart mitochondria. Dokl Biochem Biophys. 2007;415:206-10 pubmed
  28. request reprint
    Korotkov S, Nesterov V, Demina I, Ryabchikov N. Effect of diazoxide and Ca2+ on rat heart mitochondria loaded with Na+. Dokl Biochem Biophys. 2007;414:141-5 pubmed
  29. request reprint
    Korotkov S, Glazunov V, Yagodina O. Increase in the toxic effects of Tl+ on isolated rat liver mitochondria in the presence of nonactin. J Biochem Mol Toxicol. 2007;21:81-91 pubmed
    ....
  30. request reprint
    Belyaeva E, Glazunov V, Korotkov S. Cd2+ versus Ca2+-produced mitochondrial membrane permeabilization: a proposed direct participation of respiratory complexes I and III. Chem Biol Interact. 2004;150:253-70 pubmed
    ..A possible involvement of respiratory chain components, namely complex I (P-site) and complex III (S-site) in Cd2+ and/or Ca2+-produced MMP was discussed...
  31. request reprint
    Belyaeva E, Korotkov S. Mechanism of primary Cd2+-induced rat liver mitochondria dysfunction: discrete modes of Cd2+ action on calcium and thiol-dependent domains. Toxicol Appl Pharmacol. 2003;192:56-68 pubmed
    ..Suppositions about possible localization of separate sites of direct Cd2+ effects on mitochondrial function were made. ..
  32. Korotkov S, Konovalova S, Brailovskaya I, Saris N. To involvement the conformation of the adenine nucleotide translocase in opening the Tl(+)-induced permeability transition pore in Ca(2+)-loaded rat liver mitochondria. Toxicol In Vitro. 2016;32:320-32 pubmed publisher
    ..Using the Tl(+)-induced MPTP model is discussed in terms finding new transition pore inhibitors and inducers among different chemical and natural compounds. ..
  33. Korotkov S, Konovalova S, Nesterov V, Brailovskaya I. Mersalyl prevents the Tl+-induced permeability transition pore opening in the inner membrane of Ca2+-loaded rat liver mitochondria. Biochem Biophys Res Commun. 2018;495:1716-1721 pubmed publisher
    ..High MSL concentrations attenuated the ability of ADP to inhibit the MPTP. Our data suggest that the PiC can participate in the Tl+-induced MPTP opening in the inner membrane of Ca2+-loaded rat liver mitochondria. ..