L P Ovchinnikov

Summary

Country: Russia

Publications

  1. pmc Interplay between Y-box-binding protein 1 (YB-1) and poly(A) binding protein (PABP) in specific regulation of YB-1 mRNA translation
    Dmitry N Lyabin
    Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region, Russian Federation
    RNA Biol 8:883-92. 2011
  2. ncbi request reprint Novel findings on endoribonuclease activity of proteasomes
    Alexey V Sorokin
    Russian Academy of Sciences Moscow, Russia
    Cell Cycle 9:1025-30. 2010
  3. pmc Formation of amyloid-like fibrils by Y-box binding protein 1 (YB-1) is mediated by its cold shock domain and modulated by disordered terminal domains
    Sergey G Guryanov
    Group of Protein Biosynthesis Regulation, Institute of Protein Research, Russian Academy of Sciences, Pushchino, Russia
    PLoS ONE 7:e36969. 2012
  4. pmc YB-1 synthesis is regulated by mTOR signaling pathway
    Dmitry N Lyabin
    Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region, Russian Federation
    PLoS ONE 7:e52527. 2012
  5. ncbi request reprint Poly(A)-binding protein positively affects YB-1 mRNA translation through specific interaction with YB-1 mRNA
    Olga V Skabkina
    Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region 142290, Russian Federation
    J Biol Chem 278:18191-8. 2003
  6. ncbi request reprint The mRNA-binding protein YB-1 (p50) prevents association of the eukaryotic initiation factor eIF4G with mRNA and inhibits protein synthesis at the initiation stage
    Maxim P Nekrasov
    Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region, 142290 Russian Federation, Russia
    J Biol Chem 278:13936-43. 2003
  7. doi request reprint The proteolytic YB-1 fragment interacts with DNA repair machinery and enhances survival during DNA damaging stress
    Ekaterina R Kim
    Institute of Protein Research Russian Academy of Sciences Pushchino, Moscow Region, Russian Federation
    Cell Cycle 12:3791-803. 2013
  8. pmc YB-1 promotes microtubule assembly in vitro through interaction with tubulin and microtubules
    Konstantin G Chernov
    Laboratoire Structure Activité des Biomolécules Normales et Pathologiques, INSERM UEVE U829 Evry, 91025 France
    BMC Biochem 9:23. 2008
  9. ncbi request reprint [Major mRNP proteins in the structural organization and function of mRNA in eukaryotic cells]
    L P Ovchinnikov
    Mol Biol (Mosk) 35:548-58. 2001
  10. ncbi request reprint The major messenger ribonucleoprotein particle protein p50 (YB-1) promotes nucleic acid strand annealing
    M A Skabkin
    Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region 142290, Russia
    J Biol Chem 276:44841-7. 2001

Collaborators

  • A V Sorokin
  • Valentina Evdokimova
  • A S Sitikov
  • I A Eliseeva
  • D N Lyabin
  • Dmitry N Lyabin
  • M A Skabkin
  • Olga V Skabkina
  • Konstantin G Chernov
  • Ekaterina R Kim
  • Sergey G Guryanov
  • Irina A Eliseeva
  • S G Guryanov
  • O M Selivanova
  • Nadezhda V Popova
  • O V Skabkina
  • Maxim P Nekrasov
  • O A Zasedateleva
  • A N Doronin
  • L F Nigmatullina
  • Anastasia A Selyutina
  • Ilya A Buldakov
  • Dmitry A Kretov
  • Gennady A Enin
  • Alexey D Nikulin
  • Bogdan S Melnik
  • Olga M Selivanova
  • Igor N Serdyuk
  • E R Kim
  • G A Enin
  • I N Serdyuk
  • Sonia Baconnais
  • Nina A Shanina
  • David Pastre
  • P V Ruzanov
  • Elena S Nadezhdina
  • Anne Tarrade
  • Vandana Joshi
  • Patrick A Curmi
  • Alain Mechulam
  • Flavio Toma
  • Judith Melki
  • Victor D Vasiliev
  • Luiz O Penalva
  • John W B Hershey
  • Elizaveta A Kovrigina
  • Maxim A Skabkin
  • Adri A M Thomas
  • Maria P Ivshina
  • D V Prokopenko
  • A Kolchinsky
  • A D Mirzabekov
  • A S Krylov
  • A A Thomas
  • N L Korneeva
  • J W Hershey
  • A N Fedorov

Detail Information

Publications21

  1. pmc Interplay between Y-box-binding protein 1 (YB-1) and poly(A) binding protein (PABP) in specific regulation of YB-1 mRNA translation
    Dmitry N Lyabin
    Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region, Russian Federation
    RNA Biol 8:883-92. 2011
    ..Together, these results unambiguously prove direct inhibitory action of YB-1 on its mRNA translation, while the positive effect of PABP is realized through displacing YB-1 from the regulatory element...
  2. ncbi request reprint Novel findings on endoribonuclease activity of proteasomes
    Alexey V Sorokin
    Russian Academy of Sciences Moscow, Russia
    Cell Cycle 9:1025-30. 2010
    ..Comment on: Kulichkova VA, et al. Cell Cycle 2010; 9:840-9...
  3. pmc Formation of amyloid-like fibrils by Y-box binding protein 1 (YB-1) is mediated by its cold shock domain and modulated by disordered terminal domains
    Sergey G Guryanov
    Group of Protein Biosynthesis Regulation, Institute of Protein Research, Russian Academy of Sciences, Pushchino, Russia
    PLoS ONE 7:e36969. 2012
    ..We demonstrate that YB-1 fibrils have amyloid-like features, including affinity for specific dyes and a typical X-ray diffraction pattern, and that in contrast to most of amyloids, they disassemble under nearly physiological conditions...
  4. pmc YB-1 synthesis is regulated by mTOR signaling pathway
    Dmitry N Lyabin
    Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region, Russian Federation
    PLoS ONE 7:e52527. 2012
    ....
  5. ncbi request reprint Poly(A)-binding protein positively affects YB-1 mRNA translation through specific interaction with YB-1 mRNA
    Olga V Skabkina
    Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region 142290, Russian Federation
    J Biol Chem 278:18191-8. 2003
    ..Thus, PABP is capable of positively affecting YB-1 mRNA translation in a poly(A) tail-independent manner...
  6. ncbi request reprint The mRNA-binding protein YB-1 (p50) prevents association of the eukaryotic initiation factor eIF4G with mRNA and inhibits protein synthesis at the initiation stage
    Maxim P Nekrasov
    Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region, 142290 Russian Federation, Russia
    J Biol Chem 278:13936-43. 2003
    ..The accumulation is accompanied by eukaryotic initiation factor eIF4G dissociation from mRNA. The C-terminal domain of YB-1 is responsible for inhibition of translation as well as the disruption of mRNA interaction with eIF4G...
  7. doi request reprint The proteolytic YB-1 fragment interacts with DNA repair machinery and enhances survival during DNA damaging stress
    Ekaterina R Kim
    Institute of Protein Research Russian Academy of Sciences Pushchino, Moscow Region, Russian Federation
    Cell Cycle 12:3791-803. 2013
    ..We conclude that both full-length and truncated YB-1 are capable of protecting cells against DNA damaging agents, and the truncated form may have an additional function in DNA repair. ..
  8. pmc YB-1 promotes microtubule assembly in vitro through interaction with tubulin and microtubules
    Konstantin G Chernov
    Laboratoire Structure Activité des Biomolécules Normales et Pathologiques, INSERM UEVE U829 Evry, 91025 France
    BMC Biochem 9:23. 2008
    ..YB-1 is a major regulator of gene expression in eukaryotic cells. In addition to its role in transcription, YB-1 plays a key role in translation and stabilization of mRNAs...
  9. ncbi request reprint [Major mRNP proteins in the structural organization and function of mRNA in eukaryotic cells]
    L P Ovchinnikov
    Mol Biol (Mosk) 35:548-58. 2001
    ..The parts these mRNP proteins play in translation regulation, stability, and localization of mRNA are described, and the the possible mechanisms of their function are discussed...
  10. ncbi request reprint The major messenger ribonucleoprotein particle protein p50 (YB-1) promotes nucleic acid strand annealing
    M A Skabkin
    Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region 142290, Russia
    J Biol Chem 276:44841-7. 2001
    ..Our results suggest that the alteration of nucleic acid conformation is a basic mechanism of the p50-dependent regulation of gene expression...
  11. ncbi request reprint Interaction of the universal mRNA-binding protein, p50, with actin: a possible link between mRNA and microfilaments
    P V Ruzanov
    Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region, Russian Federation
    J Cell Sci 112:3487-96. 1999
    ..Together, these findings support the view that p50 may play an important role in mRNA transport, anchoring, and localization on actin filaments in the cell...
  12. doi request reprint Identification of proteins specifically interacting with YB-1 mRNA 3' UTR and the effect of hnRNP Q on YB-1 mRNA translation
    D N Lyabin
    Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia
    Biochemistry (Mosc) 78:651-9. 2013
    ....
  13. doi request reprint Y-box-binding protein 1 (YB-1) and its functions
    I A Eliseeva
    Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region, Russia
    Biochemistry (Mosc) 76:1402-33. 2011
    ..Both the oncogenic and antioncogenic activities of YB-1 are reviewed. The potential use of YB-1 in diagnostics and therapy as an early cancer marker and a molecular target is discussed...
  14. ncbi request reprint P50/YB-1, a major protein of cytoplasmic mRNPs, regulates its own synthesis
    O V Skabkina
    Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Oblast, 142290 Russia
    Dokl Biochem Biophys 395:93-5. 2004
  15. ncbi request reprint YB-1 is capable of forming extended nanofibrils
    O M Selivanova
    Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia
    Biochemistry (Mosc) 75:115-20. 2010
    ..They possess polarity and tend to associate with one another to give structures of a higher order, like ribbons or bundles. The YB-1 fibrillar architecture has a distinct periodicity with a repeat unit of about 52 nm...
  16. ncbi request reprint Interaction of eukaryotic threonyl-tRNA synthetase with high-Mr RNAs and tRNA(Thr)
    A N Fedorov
    Institute of Protein Research, Academy of Sciences of the USSR, Pushchino
    Eur J Biochem 169:185-91. 1987
    ..In the extract of rabbit reticulocytes about one-third of the threonyl-tRNA synthetase molecules are in association with cognate tRNA(Thr) and thus are unable to interact with high-Mr RNAs...
  17. ncbi request reprint The major protein of messenger ribonucleoprotein particles in somatic cells is a member of the Y-box binding transcription factor family
    V M Evdokimova
    Institute of Protein Research, Russian Academy of Sciences, Puschino, Moscow Region
    J Biol Chem 270:3186-92. 1995
    ..Highly purified p50 forms large 18 S homomultimeric complexes with a molecular mass of about 800 kilodaltons and melts RNA secondary structure. This suggests that p50 may affect translation by changing the overall structure of the mRNA...
  18. ncbi request reprint Specificity of mammalian Y-box binding protein p50 in interaction with ss and ds DNA analyzed with generic oligonucleotide microchip
    O A Zasedateleva
    Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 Vavilov Street, 119991 Moscow, Russian Federation
    J Mol Biol 324:73-87. 2002
    ....
  19. doi request reprint Poly(A)-binding proteins: structure, domain organization, and activity regulation
    I A Eliseeva
    Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia
    Biochemistry (Mosc) 78:1377-91. 2013
    ..This review presents modern notions of the role of PABPs in mRNA-dependent events; peculiarities of regulation of PABP amount in the cell and activities are also discussed. ..
  20. ncbi request reprint Proteasome system of protein degradation and processing
    A V Sorokin
    Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region, Russia
    Biochemistry (Mosc) 74:1411-42. 2009
    ..Data on damages of the proteasome system that lead to the development of different diseases are given separately...
  21. ncbi request reprint Nucleocytoplasmic transport of proteins
    A V Sorokin
    Institute of Protein Research, Russian Academy of Sciences, 142290 Pushchino, Moscow Region, Russia
    Biochemistry (Mosc) 72:1439-57. 2007
    ....