A A Mokrushin

Summary

Affiliation: Medical School
Country: Russia

Publications

  1. doi request reprint Anti-ictogenic effects of the corticotropin-releasing factor-like peptide in the pentylenetetrazole model of seizure in brain slices
    Anatoly A Mokrushin
    I P Pavlov Institute of Physiology, Russian Academy of Science, Nab Makarova, 6, Saint Petersburg 199034, Russia Electronic address
    Epilepsy Res 108:587-91. 2014
  2. doi request reprint Corticotropin-releasing factor-like peptide modifies the AMPA-, NMDA-dependent and GABAB-ergic properties of synaptic transmissions in vitro
    Anatoly A Mokrushin
    I P Pavlov Institute of Physiology, Russian Academy of Science, nab Makarova 6, Saint Petersburg 199034, Russia Electronic address
    Regul Pept 188:1-4. 2014
  3. ncbi request reprint Neuroprotective effects of heptapeptide mystixin
    A A Mokrushin
    I P Pavlov Institute of Physiology of the Russian Academy of Sciences, Saint Petersburg, Russia
    Bull Exp Biol Med 156:59-62. 2013
  4. ncbi request reprint Effects of exogenous application of corticotropin-releasing hormone to slices of the olfactory cortex from rats with an active strategy of adaptive behavior on the water-immersion model of depression
    A A Mokrushin
    I P Pavlov Institute of Physiology, Russian Academy of Sciences, St Petersburg, Russia
    Bull Exp Biol Med 147:277-80. 2009
  5. ncbi request reprint Effects of long-term exposure of nerve cells to autoblood in in vitro model of hemorrhagic stroke
    A A Mokrushin
    I P Pavlov Institute of Physiology, Russian Academy of Sciences, St Petersburg, Russia
    Bull Exp Biol Med 146:379-81. 2008
  6. ncbi request reprint Electrophysiological characteristics of depressive states in rats with passive strategies of adaptive behavior
    A A Mokrushin
    I P Pavlov Institute of Physiology, Russian Academy of Sciences, 6 Makarov Bank, 199034, St Petersburg, Russia
    Neurosci Behav Physiol 39:275-80. 2009
  7. ncbi request reprint Heat shock protein HSP70 increases the resistance of cortical cells to glutamate excitotoxicity
    A A Mokrushin
    I P Pavlov Institute of Physiology, Russian Academy of Sciences B P Konstantinov St Petersburg Institute of Nuclear Researches, Russian Academy of Sciences, Gatchina
    Bull Exp Biol Med 140:1-5. 2005
  8. ncbi request reprint Effects of exogenous heat shock protein (Hsp70) on glutaminergic synaptic transmission in rat olfactory cortex in vitro
    A A Mokrushin
    Pavlov Institute of Physiology, Russian Academy of Sciences, St Petersburg
    Dokl Biol Sci 395:118-20. 2004
  9. ncbi request reprint Corticoliberin protects neurons from the negative influences of "dysfunctins" in living olfactory cortex slices
    V G Shalyapina
    I P Pavlov Institute of Physiology, Russian Academy of Sciences, 6 Makarov Bank, 199034 St Petersburg, Russia
    Neurosci Behav Physiol 33:711-6. 2003
  10. ncbi request reprint Modification of redox sites of N-methyl-D-aspartate receptors affects anoxia-induced changes in the bioelectrical activity of rat brain olfactory cortex slices
    M O Samoilov
    Laboratory for the Regulation of Brain Neuron Function, I P Pavlov Institute of Physiology, Russian Academy of Sciences, 6 Makarov Bank, 199034 St Petersburg, Russia
    Neurosci Behav Physiol 33:601-5. 2003

Collaborators

  • V G Shalyapina
  • K N Dudkin
  • M O Samoilov
  • L I Pavlinova
  • A Kh Khama-Murad
  • A X Khama-Murad
  • V G Shaliapina
  • D G Semenov
  • G S Belyaeva
  • E V Lazarevich
  • D Yu Romanovskii
  • E I Tyul'kova
  • E A Milyakova
  • A I Erofeev
  • N N Nesterov
  • E I Tiul'kova
  • D Iu RomanovskiÄ­
  • E A Miliakova

Detail Information

Publications22

  1. doi request reprint Anti-ictogenic effects of the corticotropin-releasing factor-like peptide in the pentylenetetrazole model of seizure in brain slices
    Anatoly A Mokrushin
    I P Pavlov Institute of Physiology, Russian Academy of Science, Nab Makarova, 6, Saint Petersburg 199034, Russia Electronic address
    Epilepsy Res 108:587-91. 2014
    ..These findings indicate that the MTX mini-peptide has pronounced anti-ictogenic properties. ..
  2. doi request reprint Corticotropin-releasing factor-like peptide modifies the AMPA-, NMDA-dependent and GABAB-ergic properties of synaptic transmissions in vitro
    Anatoly A Mokrushin
    I P Pavlov Institute of Physiology, Russian Academy of Science, nab Makarova 6, Saint Petersburg 199034, Russia Electronic address
    Regul Pept 188:1-4. 2014
    ....
  3. ncbi request reprint Neuroprotective effects of heptapeptide mystixin
    A A Mokrushin
    I P Pavlov Institute of Physiology of the Russian Academy of Sciences, Saint Petersburg, Russia
    Bull Exp Biol Med 156:59-62. 2013
    ..The peptide in a dose of 250 mg/ml suppressed epileptic discharges induced by chemical convulsive agent pentylenetetrazole. Thus, heptapeptide mystixin exhibited significant neuroprotective properties. ..
  4. ncbi request reprint Effects of exogenous application of corticotropin-releasing hormone to slices of the olfactory cortex from rats with an active strategy of adaptive behavior on the water-immersion model of depression
    A A Mokrushin
    I P Pavlov Institute of Physiology, Russian Academy of Sciences, St Petersburg, Russia
    Bull Exp Biol Med 147:277-80. 2009
    ..Our results indicate that the depressive state of behaviorally active animals due to exposure to unavoidable stress is not necessarily mediated by the corticoliberinergic mechanisms in cortical structures...
  5. ncbi request reprint Effects of long-term exposure of nerve cells to autoblood in in vitro model of hemorrhagic stroke
    A A Mokrushin
    I P Pavlov Institute of Physiology, Russian Academy of Sciences, St Petersburg, Russia
    Bull Exp Biol Med 146:379-81. 2008
    ..Delayed effects of autoblood were detected, manifesting in the progress in disorders of nerve cell activity with prolongation of exposure in the blood, and the period after which they could be restored was determined...
  6. ncbi request reprint Electrophysiological characteristics of depressive states in rats with passive strategies of adaptive behavior
    A A Mokrushin
    I P Pavlov Institute of Physiology, Russian Academy of Sciences, 6 Makarov Bank, 199034, St Petersburg, Russia
    Neurosci Behav Physiol 39:275-80. 2009
    ..Thus, activation of corticoliberinergic mechanisms in cortical structures does not promote recovery from depressive states in rats with the passive behavioral strategy induced by unavoidable stress...
  7. ncbi request reprint Heat shock protein HSP70 increases the resistance of cortical cells to glutamate excitotoxicity
    A A Mokrushin
    I P Pavlov Institute of Physiology, Russian Academy of Sciences B P Konstantinov St Petersburg Institute of Nuclear Researches, Russian Academy of Sciences, Gatchina
    Bull Exp Biol Med 140:1-5. 2005
    ..It was hypothesized that heat shock protein protects AMPA and NMDA receptor-mediated processes...
  8. ncbi request reprint Effects of exogenous heat shock protein (Hsp70) on glutaminergic synaptic transmission in rat olfactory cortex in vitro
    A A Mokrushin
    Pavlov Institute of Physiology, Russian Academy of Sciences, St Petersburg
    Dokl Biol Sci 395:118-20. 2004
  9. ncbi request reprint Corticoliberin protects neurons from the negative influences of "dysfunctins" in living olfactory cortex slices
    V G Shalyapina
    I P Pavlov Institute of Physiology, Russian Academy of Sciences, 6 Makarov Bank, 199034 St Petersburg, Russia
    Neurosci Behav Physiol 33:711-6. 2003
    ..quot; It is suggested that corticoliberin can induce its protective effects either via its own specific receptors or non-specifically via glutamate receptors. It is also possible that both of these mechanisms act in combination...
  10. ncbi request reprint Modification of redox sites of N-methyl-D-aspartate receptors affects anoxia-induced changes in the bioelectrical activity of rat brain olfactory cortex slices
    M O Samoilov
    Laboratory for the Regulation of Brain Neuron Function, I P Pavlov Institute of Physiology, Russian Academy of Sciences, 6 Makarov Bank, 199034 St Petersburg, Russia
    Neurosci Behav Physiol 33:601-5. 2003
    ..The possible role of changes in the state of modulatory redox sites of NMDA receptors in the mechanisms of functional damage and increases in neuron resistance due to hypoxia is discussed...
  11. ncbi request reprint Effects of corticoliberin on synaptic transmission in rat olfactory cortex slices in a water immersion model of depression
    V G Shalyapina
    I P Pavlov Institute of Physiology, Russian Academy of Sciences, 6 Makarov Bank, 199034, St Petersburg, Russia
    Neurosci Behav Physiol 39:701-7. 2009
    ..These data support the involvement of corticoliberin in the development of depression...
  12. doi request reprint Neuroprotective properties of l-carnosine in the brain slices exposed to autoblood in the hemorrhagic stroke model in vitro
    A Kh Khama-Murad
    Pavlov Institute Physiology, Russian Academy Sciences, Saint Petersburg, Russia
    Regul Pept 167:65-9. 2011
    ..This model of hemorrhagic stroke may provide a perspective for investigating the mechanisms of neuroprotection...
  13. ncbi request reprint [Adaptive effects of hypoxic preconditioning in brain neurons]
    M O Samoilov
    I P Pavlov Institute of Physiology, Russian Acad Sci, 199034, St Petersburg, Nab Makarova, 6
    Ross Fiziol Zh Im I M Sechenova 87:714-29. 2001
    ....
  14. ncbi request reprint Neurophysiological effects of corticotropin-releasing factor in living slices of the olfactory area of the rat cortex
    A A Mokrushin
    I P Pavlov Institute of Physiology, Russian Academy of Sciences, St Petersburg
    Neurosci Behav Physiol 34:1-4. 2004
    ..These data provide evidence that CRF has marked activatory properties and influences the glutamatergic and GABAergic systems...
  15. ncbi request reprint Effects of heparin on synaptic activity in the hemorrhagic stroke model in vitro
    A A Mokrushin
    I P Pavlov Institute of Physiology, Russian Academy of Sciences, St Petersburg, Russia
    Bull Exp Biol Med 152:684-7. 2012
    ..Administration of heparin (2 mg/ml) before autoblood treatment had a protective effect on ionotropic glutamatergic and GABAergic receptors, whose activity was inhibited by the blood...
  16. ncbi request reprint Heat-shock protein (Hsp70) protects glutamatergic synaptic transmission in cells of the rat olfactory cortex against acute anoxia in vitro
    A A Mokrushin
    Pavlov Institute of Physiology, Russian Academy of Sciences, nab Makarova 6, St Petersburg, 199034 Russia
    Dokl Biol Sci 394:12-5. 2004
  17. ncbi request reprint Neurotropic effect of exogenous L-carnosine in cultured slices of the olfactory cortex from rat brain
    A X Khama-Murad
    I P Pavlov Institute of Physiology, Russian Academy of Sciences, St Petersburg, Russia
    Bull Exp Biol Med 146:1-3. 2008
    ..The effect of L-carnosine is mediated by its effect on AMPA- and NMDA-related glutamatergic receptors and on inhibitory GABAB receptors...
  18. ncbi request reprint Heat-shock protein (HSP70) as a mediator of volume signal transmission in the olfactory cerebral cortex of rats
    A A Mokrushin
    Pavlov Institute of Physiology, Russian Academy of Sciences, nab Makarova 6, St Petersburg, 199034, Russia
    Dokl Biol Sci 401:81-4. 2005
  19. ncbi request reprint [Corticoliberin protects the olfactory cortex slices against the negative effect of "dysfunctins"]
    V G Shaliapina
    I P Pavlov Institute of Physiology, Russian Acad Sci, St Petersburg, 199034, Nab Makarova, 6
    Ross Fiziol Zh Im I M Sechenova 88:332-9. 2002
    ..Corticoliberin may induce protective effects via its specific receptors or unspecifically by means of the glutamate receptors. A combined action of these mechanisms is also possible...
  20. ncbi request reprint The adaptive effects of hypoxic preconditioning of brain neurons
    M O Samoilov
    I P Pavlov Institute of Physiology, Russian Academy of Sciences, 6 Makarov Bank, 199034 St Petersburg, Russia
    Neurosci Behav Physiol 33:1-11. 2003
    ....
  21. ncbi request reprint Effects of brain peptides on instrumental learning in monkeys Macaca fascicularis
    G S Belyaeva
    Pavlov Institute of Physiology, Russian Academy of Sciences, nab Makarova 6, St Petersburg, 199034 Russia
    Dokl Biol Sci 387:491-4. 2002
  22. ncbi request reprint [Modification of redox sites of N-methyl-D-aspartate receptors affects changes in bioelectrical activity of olfactory cortex slices induced by anoxia in rats]
    M O Samoilov
    I P Pavlov Institute of Physiology, Russian Acad Sci, St Petersburg, 199034, Nab Makarova, 6
    Ross Fiziol Zh Im I M Sechenova 88:176-83. 2002
    ..A possible role of changes of the NMDA receptor modulatory redox sites in mechanisms of functional disturbances and increasing neuronal resistance induced by hypoxic influences, is discussed...