Research Topics
| N N LermontovaSummaryCountry: Russia Publications
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Detail Information
Publications
Dimebon and tacrine inhibit neurotoxic action of beta-amyloid in culture and block L-type Ca(2+) channelsN N Lermontova
Department of Biological Research, Institute of Physiologically Active Substances, Russian Academy of Sciences, Chernogolovka, Moscow Region
Bull Exp Biol Med 132:1079-83. 2001..It was assumed that the neuroprotective effect of dimebon and tacrine against Abeta25-35 partially depends on inhibition of potential-dependent Ca(2+) entry...
Comparison of the effect of NT-0409 and antidementia drugs on learning and memory in rats with chronic cerebral cholinergic deficiencyN N Lermontova
Laboratory of Neurochemistry, Institute of Physiologically Active Substances, Russian Academy of Sciences, Chernogolovka
Bull Exp Biol Med 135:48-51. 2003..NT-0409 is close to memantine by the effect on learning and, in contrast to cholinomimetic arisept, ensures longer retention of the developed habit...
Autoantibodies to beta-amyloid and neurotransmitters in patients with Alzheimer's disease and senile dementia of the Alzheimer typeM A Myagkova
Laboratory of Neurochemistry, Institute of Physiologically Active Substances, Russian Academy of Sciences, Chernogolovka, Moscow Region, Russia
Bull Exp Biol Med 131:127-9. 2001..These results can be used for the development of a biochemical method for differential diagnosis of Alzheimer dementias...
The effects of estrogens on learning in rats with chronic brain cholinergic deficiency in a Morris water test. Identification of the "passive swimming" componentT V Mukhina
Neurochemistry Laboratory, Institute of Physiologically Active Substances, Russian Academy of Sciences, Chernogolovka
Neurosci Behav Physiol 34:213-9. 2004..The new parameters (especially trajectory straightness) allowed the ability to learn to be discriminated from decreases in mobility, including mobility losses due to study agents, in the Morris water test...
[Effects of estrogens on learning of rats with chronic brain cholinergic deficit in Morris water maze]T V Mukhina
Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, Moscow Oblast
Zh Vyssh Nerv Deiat Im I P Pavlova 53:208-14. 2003....
Versatile computerized system for tracking and analysis of water maze testsT V Mukhina
Laboratory of Neurochemistry, Institute of Physiologically Active Compounds, Russian Academy of Sciences, 142432, Chernogolovka, Moscow, Russia
Behav Res Methods Instrum Comput 33:371-80. 2001..The effectiveness of this system was demonstrated in two experiments with neurochemically lesioned and drug-treated rats...
Content of autoantibodies to bradykinin and beta-amyloid(1-42) as a criterion for biochemical differences between Alzheimer's dementiasM A Myagkova
Department of Biochemical Assays, Institute of Physiologically Active Substances, Russian Academy of Sciences, Chernogolovka
Bull Exp Biol Med 136:49-52. 2003..Our results can be used for the development of a new biochemical method for differential diagnostics of dementias of the Alzheimer type...
Development of neuronal ganglion xenografts from gastropoda in rat brainE V Loseva
Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Science, Moscow
Bull Exp Biol Med 132:689-94. 2001..Rapid enlargement of the xenograft was due to cell reactive processes in the ganglion. Deep penetration of large vessels from xenografts to rat brain was observed...
Comparison of reactive processes in the rat brain elicited by xenotransplantation of nervous tissues of chicken or pulmonate snailE V Loseva
Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Butlerova 5A, GSP-7, 117485, Moscow, Russia
Brain Res 915:125-32. 2001..Putative snail vessels grew into the rat brain from the place of snail tissue transplantation serving the humoral integration of the XG and the host brain. Migration of molluscan glial cells was observed in the brain of recipients...
