E E Zvartau

Summary

Affiliation: Institute of Cytology
Country: Russia

Publications

  1. ncbi request reprint Marinobufagenin (MBG) suppression of ethanol-seeking behavior is associated with inhibition of brain cortex Na/K-ATPase in mice
    Vladimir A Kashkin
    Department of Psychopharmacology, Valdman Institute of Pharmacology, Pavlov Medical University, 6 8 Lev Tolstoy Street, St Petersburg 197089, Russia
    Eur Neuropsychopharmacol 12:217-23. 2002
  2. ncbi request reprint Caffeine place conditioning in rats: comparison with cocaine and ethanol
    N A Patkina
    Department of Psychopharmacology, Valdman Institute of Pharmacology, Pavlov Medical University, St Petersburg, Russia
    Eur Neuropsychopharmacol 8:287-91. 1998
  3. ncbi request reprint Analgesic effect of olipiphate on mouse model of chemical stimulation of peritoneum
    E E Zvartau
    I P Pavlov Medical University, St Petersburg
    Bull Exp Biol Med 131:254-6. 2001
  4. ncbi request reprint Effects of NMDA receptor antagonists on cocaine-conditioned motor activity in rats
    A Y Bespalov
    Laboratory of Behavioral Pharmacology, Department of Psychopharmacology, Institute of Pharmacology, Pavlov Medical University, 6 8 Lev Tolstoy St, St Petersburg, Russia
    Eur J Pharmacol 390:303-11. 2000
  5. ncbi request reprint Effects of the NMDA receptor antagonist, D-CPPene, on sensitization to the operant decrement produced by naloxone in morphine-treated rats
    A Y Bespalov
    Department of Psychopharmacology, Valdman Institute of Pharmacology, Pavlov Medical University, St Petersburg, Russia
    Behav Pharmacol 12:135-42. 2001
  6. ncbi request reprint Opioid-NMDA receptor interactions may clarify conditioned (associative) components of opioid analgesic tolerance
    A Y Bespalov
    Department of Psychopharmacology, Valdman Institute of Pharmacology, Pavlov Medical University, 6 8 Lev Tolstoy Str, St Petersburg 197089, Russia
    Neurosci Biobehav Rev 25:343-53. 2001
  7. ncbi request reprint Caffeine withdrawal syndrome in social interaction test in mice: effects of the NMDA receptor channel blockers, memantine and neramexane
    I A Sukhotina
    Laboratory of Behavioral Pharmacology, Department of Psychopharmacology, Institute of Pharmacology, Pavlov Medical University, St Petersburg 197089, Russia
    Behav Pharmacol 15:207-14. 2004
  8. ncbi request reprint Effects of mGlu1 receptor blockade on working memory, time estimation, and impulsivity in rats
    Irina A Sukhotina
    Laboratory of Behavioral Pharmacology, Institute of Pharmacology, Pavlov Medical University, 6 8 Leo Tolstoy Str, St Petersburg, 197089, Russia
    Psychopharmacology (Berl) 196:211-20. 2008
  9. ncbi request reprint mGlu1 receptor blockade attenuates cue- and nicotine-induced reinstatement of extinguished nicotine self-administration behavior in rats
    Olga A Dravolina
    Laboratory of Behavioral Pharmacology, Institute of Pharmacology, Pavlov Medical University, 6 8 Lev Tolstoy Street, St Petersburg 197089, Russia
    Neuropharmacology 52:263-9. 2007
  10. doi request reprint Interaction of blockers of ionotropic NMDA receptors and metabotropic glutamate receptors in a working memory test in rats
    Y A Novitskaya
    Department of Psychopharmacology, Valdman Institute of Pharmacology, Pavlov St Petersburg State Medical University, St Petersburg, Russia
    Neurosci Behav Physiol 40:807-11. 2010

Research Grants

  1. HIV/AIDS and Opportunistic Infections in IDU
    Edwin Zvartau; Fiscal Year: 2002
  2. INTRAVENOUS SELF-ADMINISTRATION IN DRUG-NAIVE MICE
    Edwin Zvartau; Fiscal Year: 2003

Collaborators

  • O Yu Vekovischeva
  • Anton Bespalov
  • Wojciech Danysz
  • P M Beardsley
  • I A Sukhotina
  • J H Krystal
  • Elena A Blokhina
  • Olga A Dravolina
  • Y A Novitskaya
  • Vladimir A Kashkin
  • Evgeny M Krupitsky
  • E M Kruptisky
  • Ivan O Medvedev
  • Olga N Neznanova
  • O A Dravolina
  • T Y Slavina
  • Tatyana Y Slavina
  • M V Tsoy
  • Olga Neznanova
  • Elena V Shekunova
  • V Y Egorova
  • Alexander A Grinenko
  • Marina Tsoy
  • Ismene L Petrakis
  • Dimitry Masalov
  • A Y Grinenko
  • Brian Pittman
  • A M Burakov
  • Ralitza Gueorguieva
  • G E Woody
  • Andrey M Burakov
  • Tatyana Didenko
  • Tatyana Romanova
  • Elena S Zakharova
  • N A Patkina
  • Andrey A Malyshkin
  • Kamal Aliev
  • Natalia Y Sevostianova
  • Robert L Balster
  • Chris G Parsons
  • Irina V Belozertseva
  • Olga V Fedorova
  • Yakov Y Bagrov
  • Natalia I Agalakova
  • Alexei Y Bagrov
  • Nadezhda A Patkina

Detail Information

Publications18

  1. ncbi request reprint Marinobufagenin (MBG) suppression of ethanol-seeking behavior is associated with inhibition of brain cortex Na/K-ATPase in mice
    Vladimir A Kashkin
    Department of Psychopharmacology, Valdman Institute of Pharmacology, Pavlov Medical University, 6 8 Lev Tolstoy Street, St Petersburg 197089, Russia
    Eur Neuropsychopharmacol 12:217-23. 2002
    ..We hypothesize that endogenous digitalis-like factors could modulate the reinforcing effect of ethanol...
  2. ncbi request reprint Caffeine place conditioning in rats: comparison with cocaine and ethanol
    N A Patkina
    Department of Psychopharmacology, Valdman Institute of Pharmacology, Pavlov Medical University, St Petersburg, Russia
    Eur Neuropsychopharmacol 8:287-91. 1998
    ..The proposed modification of conditioned place preference procedure may be useful for the comparison of rewarding values of different drugs with presumed addictive potential...
  3. ncbi request reprint Analgesic effect of olipiphate on mouse model of chemical stimulation of peritoneum
    E E Zvartau
    I P Pavlov Medical University, St Petersburg
    Bull Exp Biol Med 131:254-6. 2001
    ..Both agents dose-dependently decreased the number of motor reactions caused by the irritant. Olipiphate possessed analgesic activity and efficiency comparable with those of paracetamol, but produced a more long-lasting effect...
  4. ncbi request reprint Effects of NMDA receptor antagonists on cocaine-conditioned motor activity in rats
    A Y Bespalov
    Laboratory of Behavioral Pharmacology, Department of Psychopharmacology, Institute of Pharmacology, Pavlov Medical University, 6 8 Lev Tolstoy St, St Petersburg, Russia
    Eur J Pharmacol 390:303-11. 2000
    ..These results show that cocaine-conditioned behaviors can be selectively modulated by some, but not all, NMDA receptor antagonists...
  5. ncbi request reprint Effects of the NMDA receptor antagonist, D-CPPene, on sensitization to the operant decrement produced by naloxone in morphine-treated rats
    A Y Bespalov
    Department of Psychopharmacology, Valdman Institute of Pharmacology, Pavlov Medical University, St Petersburg, Russia
    Behav Pharmacol 12:135-42. 2001
    ..Thus, these results suggest that agonist-induced sensitization to behavioral effects of opioid antagonists may be insensitive to NMDA receptor blockade...
  6. ncbi request reprint Opioid-NMDA receptor interactions may clarify conditioned (associative) components of opioid analgesic tolerance
    A Y Bespalov
    Department of Psychopharmacology, Valdman Institute of Pharmacology, Pavlov Medical University, 6 8 Lev Tolstoy Str, St Petersburg 197089, Russia
    Neurosci Biobehav Rev 25:343-53. 2001
    ..Such 'intra-drug' conditioning hypothesis is well in line with the current experimental evidence but further studies will be needed to verify it directly...
  7. ncbi request reprint Caffeine withdrawal syndrome in social interaction test in mice: effects of the NMDA receptor channel blockers, memantine and neramexane
    I A Sukhotina
    Laboratory of Behavioral Pharmacology, Department of Psychopharmacology, Institute of Pharmacology, Pavlov Medical University, St Petersburg 197089, Russia
    Behav Pharmacol 15:207-14. 2004
    ..Both compounds dose-dependently reduced the expression of defensive behaviours while increasing motor activity. These data suggest that NMDA receptor blockade may counteract the acute behavioural effects of caffeine withdrawal...
  8. ncbi request reprint Effects of mGlu1 receptor blockade on working memory, time estimation, and impulsivity in rats
    Irina A Sukhotina
    Laboratory of Behavioral Pharmacology, Institute of Pharmacology, Pavlov Medical University, 6 8 Leo Tolstoy Str, St Petersburg, 197089, Russia
    Psychopharmacology (Berl) 196:211-20. 2008
    ..Metabotropic glutamate 1 (mGlu1) receptor antagonists were reported to induce cognitive deficits in several animal models using aversive learning procedures...
  9. ncbi request reprint mGlu1 receptor blockade attenuates cue- and nicotine-induced reinstatement of extinguished nicotine self-administration behavior in rats
    Olga A Dravolina
    Laboratory of Behavioral Pharmacology, Institute of Pharmacology, Pavlov Medical University, 6 8 Lev Tolstoy Street, St Petersburg 197089, Russia
    Neuropharmacology 52:263-9. 2007
    ..Taken together with the previous reports, the present findings further suggest that blockade of mGlu1 receptors may be beneficial for preventing relapse to tobacco smoking in nicotine-dependent individuals...
  10. doi request reprint Interaction of blockers of ionotropic NMDA receptors and metabotropic glutamate receptors in a working memory test in rats
    Y A Novitskaya
    Department of Psychopharmacology, Valdman Institute of Pharmacology, Pavlov St Petersburg State Medical University, St Petersburg, Russia
    Neurosci Behav Physiol 40:807-11. 2010
    ..Administration of MTEP (5.0 mg/kg) combined with both solvent and with MK-801 had no significant effects, demonstrating the small or nonexistent involvement of mGlu5 receptors in the mechanisms of working memory...
  11. ncbi request reprint Effects of N-methyl-D-aspartate receptor antagonists on reinstatement of cocaine-seeking behavior by priming injections of cocaine or exposures to cocaine-associated cues in rats
    A Y Bespalov
    Department of Psychopharmacology, Institute of Pharmacology, Pavlov Medical University, St Petersburg, Russia
    Behav Pharmacol 11:37-44. 2000
    ..These data help define the boundaries within which N-methyl-D-aspartate receptor antagonists can prevent reinstatement of cocaine-seeking behavior (e.g. type of antagonist used and reinstatement procedure)...
  12. ncbi request reprint Overcoming opioid blockade from depot naltrexone (Prodetoxon)
    E M Kruptisky
    St Petersburg Regional Center in Addiction and Psychopharmacology affiliated with Pavlov State Medical University, St Petersburg, Russia
    Addiction 102:1164-5. 2007
    ..To describe a situation in which an opioid-dependent patient overcame naltrexone blockade. DESIGN, CASE REPORT, SETTING: Addiction treatment center in St Petersburg, Russia...
  13. ncbi request reprint Effects of morphine and cocaine in mice with stable high aggressive and nonaggressive behavioral strategy
    Olga Yu Vekovischeva
    Department of Psychopharmacology, Valdman Institute of Pharmacology, Pavlov State Medical University, Lev Tolstoy str, 6 8, 197089, St Petersburg, Russia
    Pharmacol Biochem Behav 77:235-43. 2004
    ..Our results illustrate that social experience in a stable group alter mouse sensitivity to the rewarding properties of drugs of abuse and social state should be taken into account in the experiments when social interactions are present...
  14. ncbi request reprint Effects of nicotinic and NMDA receptor channel blockers on intravenous cocaine and nicotine self-administration in mice
    Elena A Blokhina
    Department of Psychopharmacology, Institute of Pharmacology, Pavlov Medical University, 6 8 Lev Tolstoy Street, St Petersburg 197089, Russia
    Eur Neuropsychopharmacol 15:219-25. 2005
    ..Taken together with the previous reports, these results indicate that nicotinic receptor blockers antagonize acute reinforcing effects of cocaine while NMDA receptor blockade may have limited effectiveness...
  15. ncbi request reprint Behavioral analysis of the saccharin deprivation effect in rats
    Olga N Neznanova
    Laboratory of Behavioral Pharmacology, Institute of Pharmacology, Pavlov Medical University, St Petersburg, Russia
    Behav Neurosci 116:747-56. 2002
    ..Thus, DE procedures may be useful for studying the effects of continued exposure to stimuli associated with various primary reinforcers such as drugs of abuse...
  16. ncbi request reprint Effects of low-affinity NMDA receptor channel blockers in two rat models of chronic pain
    Ivan O Medvedev
    Institute of Pharmacology, Pavlov Medical University, 6 8 Lev Tolstoy Street, 197089 St Petersburg, Russia
    Neuropharmacology 47:175-83. 2004
    ..Thus, studies on the prevention and management of chronic pain should focus on preemptive or long-term administration of NMDA receptor antagonists...
  17. ncbi request reprint Effect of memantine on cue-induced alcohol craving in recovering alcohol-dependent patients
    Evgeny M Krupitsky
    Pavlov State Medical University, St Petersburg, Russia
    Am J Psychiatry 164:519-23. 2007
    ..The authors assessed whether the NMDA receptor antagonist memantine reduces cue-induced alcohol craving and produces ethanol-like subjective effects...
  18. ncbi request reprint Intravenous self-administration of abused solvents and anesthetics in mice
    Elena A Blokhina
    Department of Psychopharmacology, Institute of Pharmacology, Pavlov Medical University, 6 8 Leo Tolstoy Street, St Petersburg 197089, Russia
    Eur J Pharmacol 485:211-8. 2004
    ..These data suggest that the reinforcing effects of abused inhalants can be studied using i.v. self-administration procedures...

Research Grants2

  1. HIV/AIDS and Opportunistic Infections in IDU
    Edwin Zvartau; Fiscal Year: 2002
    ..Multidisciplinary approach will provide the necessary grounds for development of an application for CIPRA U01 Grant. ..
  2. INTRAVENOUS SELF-ADMINISTRATION IN DRUG-NAIVE MICE
    Edwin Zvartau; Fiscal Year: 2003
    ....