Research Topics
Genomes and Genes | N K PopovaSummaryAffiliation: Institute of Cytology and Genetics Country: Russia Publications
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Publications
Ameliorative effect of BDNF on prenatal ethanol and stress exposure-induced behavioral disordersNina K Popova
Department of Behavioral Neurogenomics, Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Lavrentyeva av 10, 630090 Novosibirsk, Russia
Neurosci Lett 505:82-6. 2011..The results provide the first evidence that BDNF improves epigenetic impairment of behavior and may have profound implications in the treatment of neurologic disorders induced by early environmental challenges...
From genes to aggressive behavior: the role of serotonergic systemNina K Popova
Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia
Bioessays 28:495-503. 2006....
5-HT(1A) receptor antagonist p-MPPI attenuates acute ethanol effects in mice and ratsNina K Popova
Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Lavrentyeva 10, 630090 Novosibirsk, Russia
Neurosci Lett 322:1-4. 2002..It was concluded that 5-HT(1A) receptors were involved in the mechanisms of the ethanol-induced hypothermia and sleep, and that 5-HT(1A) antagonist increased acute ethanol tolerance...
Immobility and hyperthermia in the tail suspension test: association with the Porsolt test and the reflex startle reaction in 11 inbred mouse strains and the effects of genetic knockout of MAO AN K Popova
Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Novosibirsk, Russia
Neurosci Behav Physiol 40:489-94. 2010..These data provide grounds for using the TST as a "dry" Porsolt test and identify TST-induced hyperthermia as a model for reactions to unavoidable stress...
5-HT2A and 5-HT2C serotonin receptors differentially modulate mouse sexual arousal and the hypothalamo-pituitary-testicular response to the presence of a femaleNina K Popova
Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia
Neuroendocrinology 76:28-34. 2002..05). The present findings suggest that 5-HT2A/5-HT2C receptors may be involved in the neural control of male sexual motivation and arousal, presumably by exerting reciprocal facilitative (5-HT2A) or suppressive (5-HT2C) influences...
Functional characteristics of serotonin 5-HT2A and 5-HT2C receptors in the brain and the expression of the 5-HT2A and 5-HT2C receptor genes in aggressive and non-aggressive ratsN K Popova
Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Novosibirsk, Russia
Neurosci Behav Physiol 40:357-61. 2010....
Effect of monoamine oxidase gene knockout on dopamine metabolism in mouse brain structuresN K Popova
Laboratory for Neurogenomics of Behavior, Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk
Bull Exp Biol Med 137:382-4. 2004..Our results suggest that monoamine oxidases A and B and catechol-O-methyltransferase play different roles in dopamine metabolism in various brain structures...
Hypothermic effect of 5-HT1A receptor agonist: comparison of intranasal, intraperitoneal, and subcutaneous routes of administrationN K Popova
Laboratory of Behavioral Neurogenomics, Institute of Cytology and Genetics, Siberian Division of Russian Academy of Sciences, Novosibirsk, Russia
Bull Exp Biol Med 146:433-5. 2008..No genotypic differences in the effects of 5-HT1A receptor agonist administered by different routes were detected in four inbred mouse strains...
Reduction in 5-HT1A receptor density, 5-HT1A mRNA expression, and functional correlates for 5-HT1A receptors in genetically defined aggressive ratsNina K Popova
Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia
J Neurosci Res 80:286-92. 2005....
MAO A knockout attenuates adrenocortical response to various kinds of stressNina K Popova
Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Pr Lavrentieva 10, Novosibirsk 630090, Russia
Psychoneuroendocrinology 31:179-86. 2006....
Involvement of brain serotonin 5-HT1A receptors in genetic predisposition to aggressive behaviorN K Popova
Behavioral Neurogenetics Laboratory, Institute of Cytology and Genetics, Siberian Division, Russian Academy of Sciences, Novosibirsk
Neurosci Behav Physiol 37:631-5. 2007..These results led to the conclusion that 5-HT(1A) receptors play a significant role in the mechanisms of genetic predisposition to aggressive behavior...
Targeting tryptophan hydroxylase 2 in affective disorderNina K Popova
Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia
Expert Opin Ther Targets 14:1259-71. 2010..Serotonin (5-HT) has been implicated in several psychiatric disorders including schizophrenia, depressive disorder and suicide. The key and rate limiting enzyme of 5-HT synthesis is tryptophan hydroxylase 2 (TPH2)...
Regional serotonin metabolism in the brain of transgenic mice lacking monoamine oxidase AN K Popova
Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia
J Neurosci Res 66:423-7. 2001....
Involvement of the 5-HT(1A) and 5-HT(1B) serotonergic receptor subtypes in sexual arousal in male miceN K Popova
Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Pr Lavrentjeva 10, Novosibirsk, 630090, Russia
Psychoneuroendocrinology 27:609-18. 2002....
Altered behavior and alcohol tolerance in transgenic mice lacking MAO A: a comparison with effects of MAO A inhibitor clorgylineN K Popova
Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Lavrentieva 10, 630090 Novosibirsk 90, Russia
Pharmacol Biochem Behav 67:719-27. 2000..Other effects on behavior were different, suggesting the influence of long-lasting action of MAO A knockout and the involvement of a compensatory mechanism in Tg8 mice...
[Effect of four mutations (Cr,S,S(H),h) in genes for mink coat color on brain monoamine oxidase]N N Voitenko
Institute of Cytology and Genetics, Siberian Division, Russian Academy of Sciences, Novosibirsk, 630090 Russia
Genetika 37:638-42. 2001....
Behavioral characteristics of mice with genetic knockout of monoamine oxidase type AN K Popova
Laboratory of Behavioral Phenogenetics, Institute of Cytology and Genetics, Siberian Division, Russian Academy of Sciences, Novosibirsk Centre National de la Recherche Scientifique, Institute Curie, Orsay, France
Neurosci Behav Physiol 31:597-602. 2001..Knockout of the gene had no effect on movement activity on behavior in an elevated cross-shaped maze or in the test for predisposition to catalepsy...
Association between Tph2 gene polymorphism, brain tryptophan hydroxylase activity and aggressiveness in mouse strainsA V Kulikov
Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, ave Lavryentyev 10, 630090 Novosibirsk, Russia
Genes Brain Behav 4:482-5. 2005..The results support a link between the C1473G polymorphism in Tph2 gene, tryptophan hydroxylase activity and intensity of intermale aggression...
Brain serotonin metabolism during water deprivation and hydration in ratsN K Popova
Institute of Cytology and Genetics, Siberian Division, Russian Academy of Sciences, Novosibirsk
Neurosci Behav Physiol 31:327-32. 2001..including mechanisms specific for the regulation of water-electrolyte homeostasis and non-specific stress mechanisms (vasopressin and corticoliberin secretion)...
Correlation between cataleptic freezing and prepulse inhibition of the startle reflex in ratsN N Barykina
Institute of Cytology and Genetics, Siberian Division, Russian Academy of Sciences, 10 Academician Lavrent'ev Prospekt, 630090 Novosibirsk, Russia
Neurosci Behav Physiol 34:413-6. 2004....
A pharmacological evidence of positive association between mouse intermale aggression and brain serotonin metabolismA V Kulikov
Department of Behavioral Neurogenomics, Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Science, Lavrentyeva av 10, Novosibirsk 630090, Russia
Behav Brain Res 233:113-9. 2012..This result indicated that the intensity of intermale aggression, but not the threshold of aggressive reaction is positively dependent on 5-HT metabolism in mouse brain...
Effect of monoamine oxidase A knockout on resistance to long-term exposure to ethanolE A Ivanova
Laboratory of Phenogenetics of Behavior, Institute of Cytology and Genetics, Siberian Department of the Russian Academy of Sciences, Novosibirsk
Bull Exp Biol Med 133:603-5. 2002..After 30-day ethanol treatment the duration of narcotic sleep sharply decreased in C3H mice and increased in Tg8 mice, which attested to their decreased tolerance to ethanol...
Chronic administration of imipramine decreases freezing time in rats genetically predisposed to catalepsyA V Kulikov
Laboratory for Neurogenomics of Behavior, Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk
Bull Exp Biol Med 138:401-3. 2004..We recorded the time over which the rats remained in a vertical position they were placed. As differentiated from acute treatment, chronic administration of imipramine dose-dependently decreased the time of freezing in GC rats...
Effect of monoamine oxidease A knockout on the expression of 5-HTlA receptorsV S Naumenko
Institute of Cytology and Genetics, Siberian Division, Russian Academy of Sciences, pr Lavrent'eva 10, Novosibirsk, 630060 Russia
Dokl Biol Sci 402:205-7. 2005
Some physiological manifestations of the activity of the gene controlling the predisposition to pendulum-like movements in ratsV G Kolpakov
Institute of Cytology and Genetics, Siberian Division, Russian Academy of Sciences, Novosibirsk
Neurosci Behav Physiol 31:311-6. 2001..The interaction between PM and the predisposition to catalepsy is biphasic in nature and is described by a curve in the form of an inverted U...
Effect of mouse chromosome 13 terminal fragment on liability to catalepsy and expression of tryptophane hydroxylase-2, serotonin transporter, and 5-HT1A receptor genes in the brainA V Kulikov
Laboratory of Behavioral Neurogenomics, Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia
Bull Exp Biol Med 147:621-4. 2009..The recipient strain genome enhanced the expression of 5-HT(1A) receptor gene in the brain without modulating the expression of catalepsy gene...
Genetic structure of hereditary catalepsy in miceA V Kulikov
Institute of Cytology and Genetics, Siberian Division of Russian Academy of Sciences, Novosibirsk, Russia
Genes Brain Behav 7:506-12. 2008....
Role of various types of serotonin receptors in regulation of drinking behavior and salt appetite in vasopressin-deficient brattleboro ratsK S Naumenko
Institute of Cytology and Genetics, Siberian Division, Russian Academy of Sciences, Novosibirsk. naumenko@ bionet.nsc.ru
Bull Exp Biol Med 131:424-6. 2001..Presumably, vasopressin regulates thirst and salt appetite by modulating sensitivity/density of various types of 5-HT receptors...
Effect of imipramine on the behavior and cerebral 5-HT1A serotonin receptors in mice genetically predisposed to catalepsyM A Tikhonova
Laboratory of Behavioral Neurogenetics, Institute of Cytology and Genetics, Siberian Division of Russian Academy of Sciences, Novosibirsk
Bull Exp Biol Med 141:48-50. 2006..NPK mice can be a convenient model for studies of the effects of antidepressant...
Selective breeding for catalepsy changes the distribution of microsatellite D13Mit76 alleles linked to the 5-HT serotonin receptor gene in miceE M Kondaurova
Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia
Genes Brain Behav 5:596-601. 2006..Mice of the S12 showed CBA-like receptor activity. These findings indicate that selective breeding for behavior can involve selection of polymorphic variants of the 5-HT(1A) receptor gene...
[Participation of various types of serotonin receptors in the regulation of drinking behavior and salt appetite in rats]K S Naumenko
Institute of Cytology and Genetics, Russian Acad. Sci, Siberian Branch, Russia, 630090, Novocibirsk, Pr. Lavrentyeva, 10
Ross Fiziol Zh Im I M Sechenova 87:360-8. 2001..Only three of the receptors under study seem to regulate salt intake by inhibiting the salt appetite...
Effect of brain-derived neurotrophic factor on behavior and key members of the brain serotonin system in genetically predisposed to behavioral disorders mouse strainsV S Naumenko
Department of Behavioral Neurogenetics, Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Science, Novosibirsk, Russia
Neuroscience 214:59-67. 2012....
From gene to aggressive behavior: the role of brain serotoninN K Popova
Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, 10 Lavrent ev Prospekt, Novosibirsk, Russia
Neurosci Behav Physiol 38:471-5. 2008....
The roles of different types of serotonin receptors in activation of the hypophyseal-testicular complex induced in mice by the presence of a femaleT G Amstislavskaya
Institute of Cytology and Genetics, Siberian Division, Russian Academy of Sciences, Novosibirsk
Neurosci Behav Physiol 34:833-7. 2004..Blockade of HHTC activation induced by the presence of females appears to involve 5-HT1A and 5-HT2C receptors, while activation involves 5-HT2A and 5-HT3 receptors...
Association of glycoprotein gp130 with hereditary catalepsy in miceA V Kulikov
Laboratory of Behavioral Neurogenomics, Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia
Genes Brain Behav 9:997-1003. 2010..CBA-D13Mit76 mice and (3) the involvement of gp130 in the mechanism of LPS-induced alteration of behavior...
Effects of chronic fluoxetine treatment on catalepsy and the immune response in mice with a genetic predisposition to freezing reactions: the roles of types 1A and 2A serotonin receptors and the tph2 and SERT genesM A Tikhonova
Behavioral Neurogenomics Laboratory, Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Siberia, Russia
Neurosci Behav Physiol 40:521-7. 2010..The possibility that the actions of fluoxetine on catalepsy and the immune response in mice with depression-like states are mediated via other serotoninergic mechanisms is discussed...
Receptor-genes cross-talk: effect of chronic 5-HT(1A) agonist 8-hydroxy-2-(di-n-propylamino) tetralin treatment on the expression of key genes in brain serotonin system and on behaviorN K Popova
Department of Behavioral Neurogenomics, Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Science, Lavrentyeva Avenue 10, Novosibirsk 630090, Russia
Neuroscience 169:229-35. 2010..The results provide the first evidence of receptor-key genes interaction in brain 5-HT system and may have profound implications in understanding the functioning of the brain neurotransmitter systems...
[Correlation between cataleptic freezing and prestimulation inhibition of the startle reflex in rats]N N Barykina
Institute of Cytology and Genetics of the Russian Acad. Sci, Siberian Branch, 10 Pr. Lavrentyeva, Novosibirsk 630090, Russia
Ross Fiziol Zh Im I M Sechenova 88:1388-93. 2002..Since impairment of the PPI and habituation of the startle reflex is considered to be characteristic of schizophrenia, it is believed than cataleptic freezing in the GC rats may be used as a model of schizophrenic psychopathology...
Effect of 5-HT2C receptor antagonist RS 102221 on mouse behaviorE G Kuznetsova
Institute of Cytology and Genetics, Siberian Division of Russian Academy of Sciences, Novosibirsk
Bull Exp Biol Med 142:76-9. 2006..Hence, RS 102221 is characterized by selective anxiolytic activity, and 5-HT2C receptors are involved in the mechanisms of anxiety and startle reflex formation...
Chronic actions of thyroxine on behavior and serotonin receptors in mouse strains with contrasting predispositions to catalepsyE A Zubkov
Novosibirsk State University, Novosibirsk, Russia
Neurosci Behav Physiol 39:909-14. 2009..These results suggest that 5-HT(2A) receptors are involved in the cataleptogenic while 5-HT(1A) receptors are involved in the anticataleptic effects of the hormone in mice...
The C1473G polymorphism in the tryptophan hydroxylase-2 gene and intermale aggression in miceA V Kulikov
Institute of Cytology and Genetics, Siberian Division, Russian Academy of Sciences, pr Lavrent'eva 10, Novosibirsk, 630090 Russia
Dokl Biol Sci 402:208-10. 2005
Distribution of the C1473G polymorphism in tryptophan hydroxylase 2 gene in laboratory and wild miceD V Osipova
Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia
Genes Brain Behav 9:537-43. 2010..According to these results, the frequency of the 1473G allele in natural populations does not exceed 0.5%, and the C1473G polymorphism is in fact a rare mutation that is possibly eliminated by the forces of natural selection...
Intracerebral administration of brain-derived neurotrophic factor (BDNF) reduces severity of cataleptic freezing in mice with genetic predisposition to catalepsyM A Tikhonova
Laboratory of Behavioral Neurogenomics, Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia
Bull Exp Biol Med 148:889-91. 2009..These findings indicate that BDNF can appear as a promising antidepressant of new generation and that ASC mice can be used as an adequate model for investigations of the mechanisms of behavior modification by BDNF...
[Analysis of possibility of genotypic correlation between fear and anxiety]M V Khrapova
Institute of Cytology and Genetics, Russian Academy of Sciences, Siberian Branch, Novosibirsk
Zh Vyssh Nerv Deiat Im I P Pavlova 51:324-8. 2001..The data indicates that the fear-induced acoustic startle response and anxious behavior in the elevated plus maze (agoraphobia) are not genetically related...
[Effect of chronic stress in prepubertal period on sexual arousal in the male rats]V V Bulygina
Institute of Cytology and Genetics, Russian Acad. Sci, Siberian Branch, Russia, 630090, Novosibirsk, Pr. Lavrentyeva, 10
Ross Fiziol Zh Im I M Sechenova 87:945-52. 2001..No long-lasting effects of pre-pubertal stress on the plasma corticosterone level in males under sexual arousal were observed...
[Serotonin metabolism in the brain during sexual motivation and activation of the murine hypothalamo-hypophyseal-testicular system]T G Amstislavskaia
Institute of Cytology and Genetics, Russian Academy of Sciences, Siberian Branch, Novosibirsk
Zh Vyssh Nerv Deiat Im I P Pavlova 51:592-7. 2001..Thus, for the first time, two stages were distinguished in male sexual arousal. They were determined according to the response of the pituitary-testicular system and involvement of serotonin in different brain regions...
Hypothalamic tryptophan hydroxylase and the hypothalamic-pituitary-adrenocortical response to water deprivation and hydration in vasopressin-deficient and normal ratsN K Popova
Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, 630090, Novosibirsk, Russia
Pflugers Arch 444:372-7. 2002..The observations show that AVP is involved in the activation of TPH induced by water deprivation. This suggests that AVP modulates the metabolism of 5-HT and the response of the 5-HT-ergic system to water deprivation...
Effects of experimental increases and decreases in thyroxine levels on the extent of cataleptic freezing reactions in ratsA V Kulikov
Institute of Cytology and Genetics, Siberian Division, Russian Academy of Sciences, 10 Lavrent ev Prospekt, 630090 Novosibirsk, Russia
Neurosci Behav Physiol 35:763-7. 2005..It is concluded that both insufficiency and excess of thyroid hormones have cataleptogenic actions, but enhance different types of catalepsy...
The effect of thyroidectomy on the expression of the mRNA of 5-HT2A serotonin receptors in the rat frontal cortexA V Kulikov
Institute of Cytology and Genetics, Siberian Division, Russian Academy of Sciences, pr. Akademika Lavrent'eva 10, Novosibirsk, 630090 Russia
Dokl Biochem Biophys 383:116-8. 2002
Dopaminergic brain system in the quaking mutant mouseE M Nikulina
Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk
Pharmacol Biochem Behav 50:333-7. 1995..5 mg/kg). The alterations found in the brain dopaminergic system of qk/qk mice may be responsible for the behavioral expression of this neurologic mutation...
[Participation of 5-HT1A-receptors in regulating various types of aggressive behavior]G B Vishnivetskaia
Institute of Cytology and Genetics, Russian Academy of Sciences, Siberian Branch, Novosibirsk
Zh Vyssh Nerv Deiat Im I P Pavlova 51:704-8. 2001..The results are discussed in terms of interaction between the well-known anxiolytic effects of 5-HT1A agonists and their antiaggressive properties...
Expression of serotonin transporter gene and startle response in rats with genetically determined fear-induced aggressionV S Naumenko
Institute of Cytology and Genetics, Siberian Division of Russian Academy of Sciences, Novosibirsk, Russia
Bull Exp Biol Med 147:81-3. 2009..The authors conclude that 5-HTT is involved in the regulation of genetically determined fear-induced aggression...
Influence of neonatal short-term reduction in brainstem alpha2A-adrenergic receptors on receptor ontogenesis, acoustic startle reflex, and prepulse inhibition in ratsGalina T Shishkina
Institute of Cytology and Genetics, Novosibirsk, Russia
Behav Neurosci 118:1285-92. 2004..Transient increases in hippocampal and amygdalar alpha2-ARs were accompanied by attenuation of acoustic startle response and impairment of PPI...
On the role of brain serotonin in expression of genetic predisposition to catalepsy in animal modelsN K Popova
Laboratory of Behavioral Phenogenetics, Russian Academy of Sciences, Siberian Branch, Novosibirsk
Am J Med Genet 60:214-20. 1995..It is suggested that hereditary catalepsy may be resulted from genetic changes in the regulation of serotonin metabolism in striatum...
The brain 5-HT1A receptor gene expression in hibernationV S Naumenko
Institute of Cytology and Genetics, Siberian Division of Russian Academy of Sciences, Novosibirsk, Russia
Genes Brain Behav 7:300-5. 2008....
Effect of chronic administration of imipramine on 2A-serotonin receptor mRNA in brain cortex of rats predisposed and resistant to catalepsyA V Kulikov
Laboratory of Behaviour Phenogenetics, Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk
Bull Exp Biol Med 134:168-70. 2002..001) and did not change this parameter in Wistar rats. These results prompted us to revise current notion on the mechanisms of chronic effect of imipramine on 2A-serotonin receptors...
Immediate and long-lasting effects of chronic stress in the prepubertal age on the startle reflexLarissa N Maslova
Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk 630090, Russia
Physiol Behav 75:217-25. 2002..Evidence was obtained indicating that genetic and environmental background in childhood may contribute to the truncation of the startle response...
Female-induced sexual arousal in male mice and rats: behavioral and testosterone responseTamara G Amstislavskaya
Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk State University, Novosibirsk, Russia
Horm Behav 46:544-50. 2004....
Serotonin transporter, 5-HT1A receptor, and behavior in DBA/2J mice in comparison with four inbred mouse strainsNina K Popova
Department of Behavioral Neurogenomics, Institute of Cytology and Genetics, Siberian Division of Russian Academy of Science, Novosibirsk, Russia
J Neurosci Res 87:3649-57. 2009....
Effect of MAO A deficiency on different kinds of aggression and social investigation in miceGalina B Vishnivetskaya
Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia
Aggress Behav 33:1-6. 2007..Thus, MAO A deficiency in Tg8 mice is accompanied by increased expression of different kinds of aggression, as well as by disruption of normal pattern of social interaction...
Central 5-HT3 receptor-induced hypothermia in mice: interstrain differences and comparison with hypothermia mediated via 5-HT1A receptorVladimir S Naumenko
Department of Behavioral Neurogenomics, Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Science, Lavrentieva av 10, Novosibirsk 630090, Russia
Neurosci Lett 465:50-4. 2009..p.) diminished hypothermia produced by centrally administered m-CPBG (40 nmol i.c.v.). The data suggest the cross-talk between 5-HT(1A) and 5-HT(3) receptors in the mechanism of 5-HT-related hypothermia...
Cross-fostering effects on weight, exploratory activity, acoustic startle reflex and corticosterone stress response in Norway gray rats selected for elimination and for enhancement of aggressiveness towards humanIrina Z Plyusnina
Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia
Behav Genet 39:202-12. 2009..e. these effects of cross-fostering were dependent on ratling genotype...
[Introduction of the human recombinant angiogenin at the early stages of postnatal development inhibits the growth of mice]N P Mertvetsov
Institute of Cytology and Genetics, Russian Academy of Sciences, pr. Lavrent'eva 10, Novosibirsk, 630090 Russia
Ontogenez 33:461-4. 2002..The effect we described as related, in al likelihood, to the known inhibitory effect of angiogenin on protein synthesis...
C1473G polymorphism in mouse tph2 gene is linked to tryptophan hydroxylase-2 activity in the brain, intermale aggression, and depressive-like behavior in the forced swim testDaria V Osipova
Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia
J Neurosci Res 87:1168-74. 2009..The B6-1473C and B6-1473G mice represent a valuable experimental model for investigating molecular mechanisms of serotonin-related behavior...
Effects of sexual experience on sexual motivation in copulatory behavior in male ratsT G Amstislavskaya
Behavioral Neurogenomics Laboratory, Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, 10 Lavrentiev Prospekt, 630090, Novosibirsk, Russia
Neurosci Behav Physiol 41:506-11. 2011..There was also an increase in the proportion of males demonstrating elements of copulatory behavior in relation to partners of predominantly social significance...
Effect of chronic thyroxine treatment on catalepsy in ratsAlexander V Kulikov
Institute of Cytology and Genetics, Russian Academy of Sciences, Lavrentyeva, 10, 630090, Novosibirsk, Russia
Neurosci Lett 330:207-9. 2002..The results are evidence of the involvement of T4 in the regulation of cataleptic freezing and suggest that predisposition to catalepsy may be caused or enhanced by a deficit of thyroid hormone...
On association between cortical 5-HT2A receptors and behavior in rats with experimental thyroid disturbancesMaria A Tikhonova
Laboratory of Behavioral Neurogenomics, Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, 10 Lavrentyev Avenue, Novosibirsk, 630090, Russia
Pharmacol Biochem Behav 82:506-14. 2005..The data attract particular attention to undesirable effects of PTU and L-thyroxine treatment on behavior...
Novel approach to the study of fur cleaning in inbred mice: effects of genotype, stress, and lipopolysaccharideAlexander V Kulikov
Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Lavrentiev Avenue 10, Novosibirsk 630090, Russia
ILAR J 51:e11-6. 2010..The described technique is fairly simple and sensitive enough to estimate the effects of both stress and LPS treatment. It can be applied to study vulnerability (or resistance) to stressors, pathogenic organisms, and toxic substances...
Quantitative RT-PCR assay of 5-HT1A and 5-HT2A serotonin receptor mRNAs using genomic DNA as an external standardAlexander V Kulikov
Institute of Cytology and Genetics, Russian Academy of Sciences, Avenue Lavrentyev, 10 630090 Novosibirsk, Russia
J Neurosci Methods 141:97-101. 2005..This presented technique is reliable, simple and can be easily set up in any neurobiological laboratory...
Association of verbal and figural creative achievement with polymorphism in the human serotonin transporter geneNina V Volf
Institute of Physiology of Siberian Branch of Russian Academy of Medical Sciences, Novosibirsk, Russia
Neurosci Lett 463:154-7. 2009..As the 5-HTTLPR polymorphism is associated with genetically defined alteration in the brain serotonergic neurotransmission our result provides an evidence of the involvement of the central serotonin system in creativity regulation...
