Ye V Parfyonova

Summary

Affiliation: Institute of Experimental Cardiology
Country: Russia

Publications

  1. ncbi request reprint Plasminogen activators in vascular remodeling and angiogenesis
    Ye V Parfyonova
    Russian Cardiology Research Center, Ministry of Health of the Russian Federation, 3 ya Cherepovskaya ul 15a, Moscow, 121552, Russia
    Biochemistry (Mosc) 67:119-34. 2002
  2. ncbi request reprint T-cadherin GPI-anchor is insufficient for apical targeting in MDCK cells
    Farida Goubaeva
    Department of Anesthesiology, Columbia University P and S, 630 West 168th Street, New York, NY 10032, USA
    Biochem Biophys Res Commun 329:624-31. 2005
  3. ncbi request reprint Urokinase plasminogen activator augments cell proliferation and neointima formation in injured arteries via proteolytic mechanisms
    O Plekhanova
    Molecular Endocrinology Laboratory, Institute of Experimental Cardiology, Cardiology Research Center, 121552, Moscow, Russia
    Atherosclerosis 159:297-306. 2001
  4. doi request reprint Oligonucleotide microarrays reveal regulated genes related to inward arterial remodeling induced by urokinase plasminogen activator
    Olga Plekhanova
    Molecular Endocrinology Laboratory, Institute of Experimental Cardiology, Cardiology Research Center, Moscow, Russia
    J Vasc Res 46:177-87. 2009
  5. ncbi request reprint Urokinase plasminogen activator in injured adventitia increases the number of myofibroblasts and augments early proliferation
    Olga S Plekhanova
    Cardiology Research Centre, Moscow, Russia
    J Vasc Res 43:437-46. 2006
  6. doi request reprint Regulation of arterial remodeling and angiogenesis by urokinase-type plasminogen activator
    Vsevolod A Tkachuk
    Cardiology Research Centre, Laboratory of Molecular Endocrinology, Moscow 121552, Russia
    Can J Physiol Pharmacol 87:231-51. 2009
  7. ncbi request reprint Urokinase increases the content and activity of matrix metalloproteinases 2 and 9 during in vivo constrictive arterial remodeling
    M A Solomatina
    Russian Research and Production Center of Cardiology, Moscow
    Bull Exp Biol Med 139:283-6. 2005
  8. ncbi request reprint Contrasting effects of urokinase and tissue-type plasminogen activators on neointima formation and vessel remodelling after arterial injury
    Yelena Parfyonova
    Molecular Endocrinology Laboratory, Institute of Experimental Cardiology, Cardiology Research Center, Moscow, Russia
    J Vasc Res 41:268-76. 2004
  9. ncbi request reprint Polyelectrolyte nanoparticles mediate vascular gene delivery
    Sergey Zaitsev
    Franz Volhard Clinic, HELIOS Klinikum Berlin at the Max Delbrück Center for Molecular Medicine, D 13125 Berlin Buch, Germany
    Pharm Res 21:1656-61. 2004
  10. ncbi request reprint T-cadherin suppresses angiogenesis in vivo by inhibiting migration of endothelial cells
    Kseniya Rubina
    Department of Biological and Medical Chemistry, Faculty of Fundamental Medicine, Lomonosov Moscow State University, 31 5, Lomonosovsky av, Moscow, 119192, Russia
    Angiogenesis 10:183-95. 2007

Collaborators

  • Alex Bobik
  • B C Berk
  • Abd Al Roof Higazi
  • Hua Cai
  • M Y Menshikov
  • Maria Philippova
  • Vsevolod A Tkachuk
  • Vsevolod Tkachuk
  • Olga S Plekhanova
  • Olga Plekhanova
  • Victoria Stepanova
  • Kseniya Rubina
  • Farida Goubaeva
  • M A Solomatina
  • Sergey Zaitsev
  • Elena Kudrjashova
  • O Plekhanova
  • Andrew I Brooks
  • Pavel Bashtrykov
  • Alice Kuo
  • Sergei Zaitsev
  • Inna Dumler
  • Douglas B Cines
  • Serge Yarovoi
  • Sergei Tkachuk
  • Khalil Bdeir
  • Michael S Marks
  • Tatiana Lebedeva
  • Alexei Poliakov
  • David G Wilkinson
  • Natalia Kalinina
  • Alexandra Potekhina
  • Ekaterina Semina
  • Anastasia Efimenko
  • Victoria V Stepanova
  • Elizaveta I Ratner
  • V A Tkachuk
  • Jay Yang
  • M Yu Men'shikova
  • E I Ratner
  • E V Parfenova
  • O S Plekhanova
  • Kevin Yiu
  • Sarah Giardina
  • Michael Böttger
  • Bernd Reiner Paulke
  • Regis Cartier
  • Oleg Vyborov
  • Annekathrin Haberland
  • Gleb Sukhorukov
  • Danila Ivanov
  • Paul Erne
  • Pavel Bashtrikov
  • Olga Iljinskaya
  • Julia Antropova
  • Therese J Resink
  • Valery Bochkov
  • Eduard Tararak
  • A Agrotis
  • S Domogatskii
  • D C Gulba
  • V Tkachuk
  • R Bibilashvily
  • V Stepanova

Detail Information

Publications14

  1. ncbi request reprint Plasminogen activators in vascular remodeling and angiogenesis
    Ye V Parfyonova
    Russian Cardiology Research Center, Ministry of Health of the Russian Federation, 3 ya Cherepovskaya ul 15a, Moscow, 121552, Russia
    Biochemistry (Mosc) 67:119-34. 2002
    ..The role of plasminogen activators in vascular remodeling in atherosclerosis, restenosis, and angiogenesis is discussed...
  2. ncbi request reprint T-cadherin GPI-anchor is insufficient for apical targeting in MDCK cells
    Farida Goubaeva
    Department of Anesthesiology, Columbia University P and S, 630 West 168th Street, New York, NY 10032, USA
    Biochem Biophys Res Commun 329:624-31. 2005
    ..Therefore, T-cadherin is an example of another rare GPI-anchored protein where the anchor itself is not sufficient for apical targeting in MDCK cells...
  3. ncbi request reprint Urokinase plasminogen activator augments cell proliferation and neointima formation in injured arteries via proteolytic mechanisms
    O Plekhanova
    Molecular Endocrinology Laboratory, Institute of Experimental Cardiology, Cardiology Research Center, 121552, Moscow, Russia
    Atherosclerosis 159:297-306. 2001
    ....
  4. doi request reprint Oligonucleotide microarrays reveal regulated genes related to inward arterial remodeling induced by urokinase plasminogen activator
    Olga Plekhanova
    Molecular Endocrinology Laboratory, Institute of Experimental Cardiology, Cardiology Research Center, Moscow, Russia
    J Vasc Res 46:177-87. 2009
    ..We conclude that uPA likely promotes inward arterial remodeling by regulating oxidative stress and inflammation after arterial injury...
  5. ncbi request reprint Urokinase plasminogen activator in injured adventitia increases the number of myofibroblasts and augments early proliferation
    Olga S Plekhanova
    Cardiology Research Centre, Moscow, Russia
    J Vasc Res 43:437-46. 2006
    ....
  6. doi request reprint Regulation of arterial remodeling and angiogenesis by urokinase-type plasminogen activator
    Vsevolod A Tkachuk
    Cardiology Research Centre, Laboratory of Molecular Endocrinology, Moscow 121552, Russia
    Can J Physiol Pharmacol 87:231-51. 2009
    ..The role of domain specificity of urokinase in these processes is also discussed...
  7. ncbi request reprint Urokinase increases the content and activity of matrix metalloproteinases 2 and 9 during in vivo constrictive arterial remodeling
    M A Solomatina
    Russian Research and Production Center of Cardiology, Moscow
    Bull Exp Biol Med 139:283-6. 2005
    ..Application of recombinant tissue plasminogen produced no such changes. It was demonstrated that urokinase stimulates expression of matrix metalloproteinases in vivo...
  8. ncbi request reprint Contrasting effects of urokinase and tissue-type plasminogen activators on neointima formation and vessel remodelling after arterial injury
    Yelena Parfyonova
    Molecular Endocrinology Laboratory, Institute of Experimental Cardiology, Cardiology Research Center, Moscow, Russia
    J Vasc Res 41:268-76. 2004
    ..We conclude that the ability to stimulate neointima formation and inward arterial remodelling is a specific property for urokinase plasminogen activator that could not be mimicked by tissue-type plasminogen activator...
  9. ncbi request reprint Polyelectrolyte nanoparticles mediate vascular gene delivery
    Sergey Zaitsev
    Franz Volhard Clinic, HELIOS Klinikum Berlin at the Max Delbrück Center for Molecular Medicine, D 13125 Berlin Buch, Germany
    Pharm Res 21:1656-61. 2004
    ..The system should be used to transfect cardiovascular tissues...
  10. ncbi request reprint T-cadherin suppresses angiogenesis in vivo by inhibiting migration of endothelial cells
    Kseniya Rubina
    Department of Biological and Medical Chemistry, Faculty of Fundamental Medicine, Lomonosov Moscow State University, 31 5, Lomonosovsky av, Moscow, 119192, Russia
    Angiogenesis 10:183-95. 2007
    ..These data suggest that T-cadherin expressed in the stroma could act as a negative guidance cue for the ingrowing blood vessels and thus could have an important potential therapeutic application...
  11. ncbi request reprint Urokinase induces matrix metalloproteinase-9/gelatinase B expression in THP-1 monocytes via ERK1/2 and cytosolic phospholipase A2 activation and eicosanoid production
    Mikhail Menshikov
    Institute of Experimental Cardiology, Cardiology Research Center, Moscow, Russia
    J Vasc Res 43:482-90. 2006
    ..We characterized the mechanisms by which uPA regulates matrix metalloproteinase-9 (MMP9) function in THP-1 monocytes...
  12. ncbi request reprint Expression of adhesion molecule T-cadherin is increased during neointima formation in experimental restenosis
    Elena Kudrjashova
    Laboratory for Molecular Endocrinology, Institute of Experimental Cardiology, 121552 Moscow, Russia
    Histochem Cell Biol 118:281-90. 2002
    ..In colchicine-treated cultures of rat aortic SMCs T-cadherin expression is increased in dividing M-phase cells but decreased in non-dividing cells. Together the data support an association between T-cadherin expression and SMC phenotype...
  13. pmc Nuclear translocation of urokinase-type plasminogen activator
    Victoria Stepanova
    Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia 19104, USA
    Blood 112:100-10. 2008
    ..These data reveal a novel pathway by which uPA is rapidly translocated to the nucleus where it might participate in regulating gene expression...
  14. ncbi request reprint Urokinase plasminogen activator stimulates vascular smooth muscle cell proliferation via redox-dependent pathways
    Mikhail Menshikov
    Cardiology Research Center, Moscow, Russia
    Arterioscler Thromb Vasc Biol 26:801-7. 2006
    ..Because increases in VSMC reactive oxygen species (ROS) contribute to VSMC proliferation, we hypothesized that uPA increases ROS generation by regulating expression or activity of cellular oxidases...