Research Topics
Species | S L KiselevSummaryAffiliation: Institute of Cytology Country: Russia Publications
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Detail Information
Publications
Molecular cloning and characterization of the mouse tag7 gene encoding a novel cytokineS L Kiselev
Institute of Gene Biology, 34 5 Vavilova St, Moscow 117334, Russia
J Biol Chem 273:18633-9. 1998..The soluble form of Tag7 triggers apoptosis in mouse L929 cells in vitro and does not involve NF-kappaB activation. The relationship between Tag7 and tumor necrosis factor family of ligands is discussed...
[Cloning and study of novel mammalian genes with structural homology with phage lysozyme]I I Mirkina
Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia
Genetika 36:1492-500. 2000..Sequence analysis suggested the possible membrane localization of the gene, whereas the specific expression pointed to the role of this gene in the immune system. Both genes, tag7 and tagL, were localized in the human chromosome 19...
[tag7 Gene and gene therapy of cancer]S L Kiselev
Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia
Genetika 36:1431-5. 2000..The results of comparative analysis of the Tag7 protein antitumor activity are presented. This evidence clearly shows that Tag7 is a promising agent for anticancer therapy...
Phosphorylation of MAK-V protein kinase in mammalian cellsI V Korobko
Institute of Gene Biology, Russian Academy of Sciences, ul. Vavilova 34/5, Moscow 119334, Russia
Dokl Biochem Biophys 412:37-9. 2007
Molecular cloning of a new mouse gene tagL containing a lysozyme-like domainA V Kibardin
Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia
Dokl Biochem 372:103-5. 2000
Dimerization properties of Rabaptin-5 and its isoformsE V Korobko
Institute of Gene Biology, Russian Academy of Sciences, Moscow, 119334, Russia
Biochemistry (Mosc) 71:1307-11. 2006..In this study, we have investigated dimerization properties of delta and gamma isoforms of Rabaptin-5. In addition, we have provided the first direct evidence for Rabaptin-5 dimerization in cells...
[Cloning of the tag7 gene expressed in metastatic mouse tumors]O S Kustikova
Genetika 32:621-8. 1996..The full-length tag7 cDNA was cloned and its nucleotide sequence was determined. No homology between the tag7 gene and known sequences was revealed. tag7 gene transcription was studied in some tumors, cell lines, and normal mouse organs...
Phase I/II trial of gene therapy with autologous tumor cells modified with tag7/PGRP-S gene in patients with disseminated solid tumors: miscellaneous tumorsV M Moiseyenko
N.N. Petrov Research Institute of Oncology, St Petersburg, Russian Federation
Ann Oncol 16:162-8. 2005..Further studies are required to determine whether promising effects on immune activation will result in an actual clinical benefit for patients with malignant melanoma and renal cell carcinoma...
[Transcription and mRNA splicing of the human lactoferrin gene controlled by the regulatory region of the bovine alphaS1 casein gene in the mammary gland of transgenic mice and in mouse embryonic stem cells]E S Zakharova
Institute of Gene Biology, Russian Academy of Sciences, Moscow, 117334 Russia
Genetika 41:299-306. 2005..However, a recombinant transcript was found in RNAs isolated from mammary glands of transgenic females during lactation and from transfected ESC lines...
Gene transfer approaches in cancer immunotherapyS S Larin
Institute of Gene Biology Russian Academy of Sciences, Moscow, Russia
Gene Ther 11:S18-25. 2004....
HSP70 forms a stable cytotoxic complex with Tag7/PGRP-SYu V Shatalov
Institute of Gene Biology, Russian Academy of Sciences, Moscow
Dokl Biol Sci 395:169-72. 2004
[Variants of adenovirus type 5 with deletions in early genes: ability for selective replication in p53-defective human tumor cells]A V Kachko
Institute of Molecular Biology, Vector State Research Center of Virology and Biotechnology, Kol tsovo, Novosibirsk Region, 630559 Russia
Mol Biol (Mosk) 37:868-75. 2003..On intratumor injection, Adel2 dramatically suppressed the growth of human epidermoid carcinoma (A431) in nude mice. Adel2 is thus a promising model for designing therapeutic agents against p53-deficient human tumors...
[The use of the two-hybrid cloning in yeast for functional characterization of protein kinase MAK-V]I V Korobko
Institute of Gene Biology, Russian Academy of Sciences, Moscow, 117334 Russia
Mol Biol (Mosk) 36:491-5. 2002..Based on the partner properties, MAK-V/Hunk was assumed to play a role in tumorigenesis and tumor progression. With the previous results of two-hybrid cloning, MAK-V/Hunk was shown to participate in vesicular transport...
Cerd4, third member of the d4 gene family: expression and organization of genomic locusN N Ninkina
Department of Preclinical Veterinary Sciences, University of Edinburgh, Summerhall, Edinburgh, EH9 1QH, Scotland, UK
Mamm Genome 12:862-6. 2001..The intron/exon structure of human Cerd4 gene is similar to that of neuro-d4 and ubi-d4/Requiem genes, but most introns of Cerd4 gene are much larger than the corresponding introns of the other two genes...
The MAK-V protein kinase regulates endocytosis in mouseI V Korobko
Institute of Gene Biology, Russian Academy of Sciences, Moscow
Mol Gen Genet 264:411-8. 2000..We also constructed a human mak-v cDNA and localized the human mak-v gene at 21q22.11. Its chromosomal location suggests that mak-v could be involved in disorders of the nervous system, development or in malignancies...
[Identification of the new protein kinase specifically transcribed in mouse tumors with high metastatic potential]I V Korobko
Dokl Akad Nauk 354:554-6. 1997
Mobile genetic elements in Drosophila melanogaster (recent experiments)G P Georgiev
Department of Nucleic Acid Biosynthesis, Engelhardt Institute of Molecular Biology, Academy of Sciences of the USSR, Moscow
Genome 31:920-8. 1989..Several novel genes were detected using mobilized Stalker. They include a modifier of mdg4 and six enhancers of yellow mutations...
A novel transposition system in Drosophila melanogaster depending on the Stalker mobile genetic elementP G Georgiev
Vavilov Institute of General Genetics, USSR Academy of Sciences, Moscow
EMBO J 9:2037-44. 1990..Many known and novel mutations have been obtained. Comparison of their genetic localization with Stalker distribution suggests that the majority of them have been induced by the Stalker insertion...
Differential splicing creates a diversity of transcripts from a neurospecific developmentally regulated gene encoding a protein with new zinc-finger motifsV L Buchman
Engelhardt Institute of Molecular Biology, Moscow, Russia
Nucleic Acids Res 20:5579-85. 1992..Several differential splicing variants were found, each of which influences the structure of the encoded protein...
