Nikolai Khlebtsov

Summary

Affiliation: Institute of Biochemistry and Physiology of Plants and Microorganisms
Country: Russia

Publications

  1. ncbi request reprint A method for studying insoluble immune complexes
    Boris N Khlebtsov
    Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, 13 Pr Entuziastov, Saratov 410049, Russia
    Biochim Biophys Acta 1670:199-207. 2004
  2. ncbi request reprint Can the light scattering depolarization ratio of small particles be greater than 1/3?
    Nikolai G Khlebtsov
    Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, 13 Pr Entuziastov, Saratov 410049, Russia
    J Phys Chem B 109:13578-84. 2005
  3. ncbi request reprint Gold nanoshell photomodification under a single-nanosecond laser pulse accompanied by color-shifting and bubble formation phenomena
    Garif Akchurin
    Saratov State University, 83 Ulitsa Astrakhanskaya, Saratov 410012, Russia
    Nanotechnology 19:015701. 2008
  4. ncbi request reprint Mutagenic effect of gold nanoparticles in the micronucleus assay
    D S Jumagazieva
    V I Razumovsky Saratov State Medical University, Saratov, Russia
    Bull Exp Biol Med 151:731-3. 2011
  5. doi request reprint Plasmonic nanopowders for photothermal therapy of tumors
    Boris N Khlebtsov
    Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, 13 Prospekt Entuziastov, Saratov 410049, Russia
    Langmuir 28:8994-9002. 2012
  6. doi request reprint Nanocomposites containing silica-coated gold-silver nanocages and Yb-2,4-dimethoxyhematoporphyrin: multifunctional capability of IR-luminescence detection, photosensitization, and photothermolysis
    Boris Khlebtsov
    Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, 13 Prospekt Entuziastov, Saratov 410049, Russia
    ACS Nano 5:7077-89. 2011
  7. doi request reprint Quantitative cell bioimaging using gold-nanoshell conjugates and phage antibodies
    Vitaly A Khanadeev
    Department of Biophysics, Saratov State University, 83 Ulitsa Astrakhanskaya, Saratov 410012, Russia
    J Biophotonics 4:74-83. 2011
  8. doi request reprint Circulation and distribution of gold nanoparticles and induced alterations of tissue morphology at intravenous particle delivery
    Georgy S Terentyuk
    Saratov State University, 83 Astrakhanskaya, 410012 Saratov, Russia
    J Biophotonics 2:292-302. 2009
  9. doi request reprint Extinction and extra-high depolarized light scattering spectra of gold nanorods with improved purity and dimension tunability: direct and inverse problems
    Boris N Khlebtsov
    Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, 13 Prospekt Entuziastov, Saratov 410049, Russia
    Phys Chem Chem Phys 16:5710-22. 2014
  10. pmc SERS substrates formed by gold nanorods deposited on colloidal silica films
    Mikhail Yu Tsvetkov
    Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, 13 Prospekt Entuziastov, Saratov 410049, Russia
    Nanoscale Res Lett 8:250. 2013

Collaborators

  • Boris Khlebtsov
  • Valery V Tuchin
  • Lev A Dykman
  • Vitaly A Khanadeev
  • Vladimir A Bogatyrev
  • Mikhail Yu Tsvetkov
  • Lev Dykman
  • L A Dykman
  • D S Jumagazieva
  • Georgy S Terentyuk
  • Garif Akchurin
  • Anna V Alekseeva
  • Mikhail I Samoylovich
  • Peter S Timashev
  • Victor N Bagratashvili
  • A B Bucharskaya
  • Alexander A Skaptsov
  • G N Maslyakova
  • L V Suleymanova
  • S S Firsova
  • G S Terentyuk
  • S M Kong
  • Ekaterina S Ileneva
  • Sergey A Staroverov
  • Irina V Vidyasheva
  • Boris Ya Kogan
  • Irina L Maksimova
  • Alexander V Shantrocha
  • Galina N Maslyakova
  • Leyla V Suleymanova
  • Garif G Akchurin
  • Georgy Akchurin
  • Vladimir Zharov
  • Lyubov A Trachuk
  • Andrei G Melnikov

Detail Information

Publications22

  1. ncbi request reprint A method for studying insoluble immune complexes
    Boris N Khlebtsov
    Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, 13 Pr Entuziastov, Saratov 410049, Russia
    Biochim Biophys Acta 1670:199-207. 2004
    ..We have found that IICP can be modeled by incompact porous particles that contain about 30% of biopolymer substance and 70% of buffer...
  2. ncbi request reprint Can the light scattering depolarization ratio of small particles be greater than 1/3?
    Nikolai G Khlebtsov
    Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, 13 Pr Entuziastov, Saratov 410049, Russia
    J Phys Chem B 109:13578-84. 2005
    ..The measured depolarization ratios of nanospheres (0.07-0.16) and nanorods (0.3-0.48) are in good agreement with theoretical calculations based on estimations of the average particle size and shape...
  3. ncbi request reprint Gold nanoshell photomodification under a single-nanosecond laser pulse accompanied by color-shifting and bubble formation phenomena
    Garif Akchurin
    Saratov State University, 83 Ulitsa Astrakhanskaya, Saratov 410012, Russia
    Nanotechnology 19:015701. 2008
    ..5 ns scale at 0.2 J cm(-2)). Application of the observed phenomena to medical applications is discussed, including a simple visual color test for laser-nanoparticle interaction...
  4. ncbi request reprint Mutagenic effect of gold nanoparticles in the micronucleus assay
    D S Jumagazieva
    V I Razumovsky Saratov State Medical University, Saratov, Russia
    Bull Exp Biol Med 151:731-3. 2011
    ....
  5. doi request reprint Plasmonic nanopowders for photothermal therapy of tumors
    Boris N Khlebtsov
    Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, 13 Prospekt Entuziastov, Saratov 410049, Russia
    Langmuir 28:8994-9002. 2012
    ..Particle biodistribution was measured by atomic absorption spectroscopy, and tumor hyperthermia effects were studied under laser NIR irradiation. Significant tumor damage was observed only at the higher dose of the nanorods...
  6. doi request reprint Nanocomposites containing silica-coated gold-silver nanocages and Yb-2,4-dimethoxyhematoporphyrin: multifunctional capability of IR-luminescence detection, photosensitization, and photothermolysis
    Boris Khlebtsov
    Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, 13 Prospekt Entuziastov, Saratov 410049, Russia
    ACS Nano 5:7077-89. 2011
    ..Thus, these multifunctional nanocomposites seem an attractive theranostic platform for simultaneous IR-luminescence diagnostic and photodynamic therapy owing to Yb-HP and for plasmonic photothermal therapy owing to Au-Ag nanocages...
  7. doi request reprint Quantitative cell bioimaging using gold-nanoshell conjugates and phage antibodies
    Vitaly A Khanadeev
    Department of Biophysics, Saratov State University, 83 Ulitsa Astrakhanskaya, Saratov 410012, Russia
    J Biophotonics 4:74-83. 2011
    ..In terms of the LEF, a distinct difference was found between intact, nonspecifically labeled, and biospecifically labeled cells...
  8. doi request reprint Circulation and distribution of gold nanoparticles and induced alterations of tissue morphology at intravenous particle delivery
    Georgy S Terentyuk
    Saratov State University, 83 Astrakhanskaya, 410012 Saratov, Russia
    J Biophotonics 2:292-302. 2009
    ..We report also preliminary data on the light microscopy and TEM histological examination that allows evaluation of the changes in biotissues after gold NPs treatment...
  9. doi request reprint Extinction and extra-high depolarized light scattering spectra of gold nanorods with improved purity and dimension tunability: direct and inverse problems
    Boris N Khlebtsov
    Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, 13 Prospekt Entuziastov, Saratov 410049, Russia
    Phys Chem Chem Phys 16:5710-22. 2014
    ....
  10. pmc SERS substrates formed by gold nanorods deposited on colloidal silica films
    Mikhail Yu Tsvetkov
    Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, 13 Prospekt Entuziastov, Saratov 410049, Russia
    Nanoscale Res Lett 8:250. 2013
    ..Several ways to further optimize the strategy suggested are discussed...
  11. doi request reprint Enhanced photoinactivation of Staphylococcus aureus with nanocomposites containing plasmonic particles and hematoporphyrin
    Boris N Khlebtsov
    Institute of Biochemistry and Physiology of Plants and Micro organisms, RAS, 13 Prospekt Entuziastov, Saratov 410049, Russia
    J Biophotonics 6:338-51. 2013
    ..By using fluorescence microscopy and spectroscopy, we explain the enhanced antimicrobial effect of hematoporphyrin-doped nanocomposites by their selective accumulation in the vicinity of the bacteria...
  12. pmc Analytical and theranostic applications of gold nanoparticles and multifunctional nanocomposites
    Nikolai Khlebtsov
    Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences IBPPM RAS, Russian Federation
    Theranostics 3:167-80. 2013
    ....
  13. pmc Gold nanoparticles in biology and medicine: recent advances and prospects
    L A Dykman
    Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences
    Acta Naturae 3:34-55. 2011
    ..Keeping in mind the huge volume and high speed of the data update rate, 2/3 of our reference list (certainly restricted to 250 Refs.) includes publications encompassing the past 5 years...
  14. doi request reprint Determination of size and concentration of gold nanoparticles from extinction spectra
    Nikolai G Khlebtsov
    Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, 13 Prospekt Entuziastov, Saratov 410049, Russia
    Anal Chem 80:6620-5. 2008
    ....
  15. doi request reprint Biodistribution and toxicity of engineered gold nanoparticles: a review of in vitro and in vivo studies
    Nikolai Khlebtsov
    Institute of Biochemistry and Physiology of Plants and Microorganisms, RAS, 13 Pr Entuziastov, Saratov 410049, Russian Federation
    Chem Soc Rev 40:1647-71. 2011
    ....
  16. ncbi request reprint Ultrasharp light-scattering resonances of structured nanospheres: effects of size-dependent dielectric functions
    Boris Khlebtsov
    Russian Academy of Sciences, Institute of Biochemistry and Physiology of Plants and Microorganisms, 13 Pr Entuziastov, Saratov 410049, Russia
    J Biomed Opt 11:044002. 2006
    ..Furthermore, contrary to the data of Chen et al., we did not find any significant advantages of three-layer structures, as compared with the usual silica/metal nanoshells...
  17. doi request reprint Tunable depolarized light scattering from gold and gold/silver nanorods
    Boris Khlebtsov
    Institute of Biochemistry and Physiology of Plants and Microorganisms, RAS, 13 Pr Entuziastov, Saratov 410049, Russian Federation
    Phys Chem Chem Phys 12:3210-8. 2010
    ....
  18. ncbi request reprint Preparation and optical scattering characterization of gold nanorods and their application to a dot-immunogold assay
    Anna V Alekseeva
    Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, 13 Prospekt Entuziastov, Saratov 410049, Russia
    Appl Opt 44:6285-95. 2005
    ..Finally, we discuss the application of NR-protein A conjugates to a dot-immunogold assay with the example of biospecific staining of human IgG molecules adsorbed onto small membrane spots...
  19. doi request reprint Gold nanoparticles in biomedical applications: recent advances and perspectives
    Lev Dykman
    Institute of Biochemistry and Physiology of Plants and Microorganisms, RAS, 13 Pr Entuziastov, Saratov 410049, Russian Federation
    Chem Soc Rev 41:2256-82. 2012
    ..Distinct from other published reviews, we present a summary of the immunological properties of GNPs. For each of the above topics, the basic principles, recent advances, and current challenges are discussed (508 references)...
  20. ncbi request reprint Enhanced solid-phase immunoassay using gold nanoshells: effect of nanoparticle optical properties
    Boris Khlebtsov
    Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, 13 Prospekt Entuziastov, Saratov 410049, Russia
    Nanotechnology 19:435703. 2008
    ..5-1 ng for 100/15 and 140/15 GNs. By using the theory developed, we explained the dependences of the low detection limit, the maximal-color intensity and the probe-load saturation limit on the particle parameters...
  21. doi request reprint Determination of the size, concentration, and refractive index of silica nanoparticles from turbidity spectra
    Boris N Khlebtsov
    Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, 13 Prospekt Entuziastov, Saratov, Russia
    Langmuir 24:8964-70. 2008
    ..005. Finally, we exemplify our method by determining the particle size and concentration for 10 samples and compare the results with transmission electron microscopy (TEM), atomic force microscopy (AFM), and dynamic light scattering data...
  22. ncbi request reprint A protein assay based on colloidal gold conjugates with trypsin
    Lev A Dykman
    Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, 13 Prospekt Entuziastov, Saratov 410049, Russia
    Anal Biochem 341:16-21. 2005
    ..The changes in the extinction spectra are presumed to be related to aggregation of gold nanoparticles caused by polyvalent binding of protein molecules to the trypsin molecules of the conjugates...